UCSF
Image of Isoxazole

Identity 99% 90% 80% 70% Substructure

Isoxazole

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Ring Information

Rings Ring Systems Atoms Carbons Nitrogens Oxygens Sulfurs
1 1 5 3 1 1 0

Subset Information

Substances Natural Purchasable Annotated BB In Man Last Updated
View 148 58,048 154 3,660 7 2012-03-06

Most Common Targets

Name (Uniprot) Swissprot ChEMBL Description Size Browse Download (Annotations)
NR1H4_HUMAN Q96RI1 CHEMBL2047 Bile Acid Receptor FXR, Human 24 Annotations Catalogs SMILES SDF Mol2 Flexibase
PPARG_HUMAN P37231 CHEMBL235 Peroxisome Proliferator-activated Receptor Gamma, Human 24 Annotations Catalogs SMILES SDF Mol2 Flexibase
NR1H4_HUMAN Q96RI1 CHEMBL2047 Bile Acid Receptor FXR, Human 19 Annotations Catalogs SMILES SDF Mol2 Flexibase
NR1H4_HUMAN Q96RI1 CHEMBL2047 Bile Acid Receptor FXR, Human 19 Annotations Catalogs SMILES SDF Mol2 Flexibase
PPARG_HUMAN P37231 CHEMBL235 Peroxisome Proliferator-activated Receptor Gamma, Human 16 Annotations Catalogs SMILES SDF Mol2 Flexibase
TRPV1_HUMAN Q8NER1 CHEMBL4794 Vanilloid Receptor, Human 16 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 11 Annotations Catalogs SMILES SDF Mol2 Flexibase
SOAT1_RAT O70536 CHEMBL285 Acyl Coenzyme A:cholesterol Acyltransferase 1, Rat 11 Annotations Catalogs SMILES SDF Mol2 Flexibase
SOAT1_RAT O70536 CHEMBL285 Acyl Coenzyme A:cholesterol Acyltransferase 1, Rat 11 Annotations Catalogs SMILES SDF Mol2 Flexibase
PPARA_HUMAN Q07869 CHEMBL239 Peroxisome Proliferator-activated Receptor Alpha, Human 8 Annotations Catalogs SMILES SDF Mol2 Flexibase
PPARD_HUMAN Q03181 CHEMBL3979 Peroxisome Proliferator-activated Receptor Delta, Human 8 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
PPARG_HUMAN P37231 CHEMBL235 Peroxisome Proliferator-activated Receptor Gamma, Human 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
PLK1_HUMAN P53350 CHEMBL3024 Serine/threonine-protein Kinase PLK1, Human 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
PLK1_HUMAN P53350 CHEMBL3024 Serine/threonine-protein Kinase PLK1, Human 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
FA10_HUMAN P00742 CHEMBL244 Coagulation Factor X, Human 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
FA10_HUMAN P00742 CHEMBL244 Coagulation Factor X, Human 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
KCNA5_HUMAN P22460 CHEMBL4306 Voltage-gated Potassium Channel Subunit Kv1.5, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
KCNA5_HUMAN P22460 CHEMBL4306 Voltage-gated Potassium Channel Subunit Kv1.5, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
MK14_HUMAN Q16539 CHEMBL260 MAP Kinase P38 Alpha, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
MK14_HUMAN Q16539 CHEMBL260 MAP Kinase P38 Alpha, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
PKD1_HUMAN P98161 CHEMBL5772 Polycystin-1, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
PKD1_HUMAN P98161 CHEMBL5772 Polycystin-1, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
VGFR2_HUMAN P35968 CHEMBL279 Vascular Endothelial Growth Factor Receptor 2, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
VGFR2_HUMAN P35968 CHEMBL279 Vascular Endothelial Growth Factor Receptor 2, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
VGFR2_HUMAN P35968 CHEMBL279 Vascular Endothelial Growth Factor Receptor 2, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50587 Z50587 CHEMBL372 Homo Sapiens 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
ALDR_BOVIN P16116 CHEMBL3081 Aldose Reductase, Bovin 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
EDNRA_RAT P26684 CHEMBL4566 Endothelin Receptor ET-A, Rat 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
EDNRA_RAT P26684 CHEMBL4566 Endothelin Receptor ET-A, Rat 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
ITA2B_HUMAN P08514 CHEMBL212 Integrin Alpha-IIb, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
ITA2B_HUMAN P08514 CHEMBL212 Integrin Alpha-IIb, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
ITB3_HUMAN P05106 CHEMBL207 Integrin Beta-3, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
ITB3_HUMAN P05106 CHEMBL207 Integrin Beta-3, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
MMP3_HUMAN P08254 CHEMBL283 Matrix Metalloproteinase 3, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
PLK2_HUMAN Q9NYY3 CHEMBL5938 Serine/threonine-protein Kinase PLK2, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
THRB_HUMAN P00734 CHEMBL204 Thrombin, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
THRB_HUMAN P00734 CHEMBL204 Thrombin, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50588 Z50588 CHEMBL373 Canis Familiaris 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
BACE1_HUMAN P56817 CHEMBL4822 Beta-secretase 1, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
CATD_HUMAN P07339 CHEMBL2581 Cathepsin D, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
CATD_HUMAN P07339 CHEMBL2581 Cathepsin D, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
DPP4_HUMAN P27487 CHEMBL284 Dipeptidyl Peptidase IV, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
DPP4_HUMAN P27487 CHEMBL284 Dipeptidyl Peptidase IV, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
MK11_HUMAN Q15759 CHEMBL3961 MAP Kinase P38 Beta, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
MK11_HUMAN Q15759 CHEMBL3961 MAP Kinase P38 Beta, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
MMP3_HUMAN P08254 CHEMBL283 Matrix Metalloproteinase 3, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
MMP8_HUMAN P22894 CHEMBL4588 Matrix Metalloproteinase 8, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
MMP8_HUMAN P22894 CHEMBL4588 Matrix Metalloproteinase 8, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
PLK2_HUMAN Q9NYY3 CHEMBL5938 Serine/threonine-protein Kinase PLK2, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
PLK3_HUMAN Q9H4B4 CHEMBL4897 Serine/threonine-protein Kinase PLK3, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q72547_9HIV1 Q72547 CHEMBL247 Human Immunodeficiency Virus Type 1 Reverse Transcriptase, 9hiv1 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
SOAT1_HUMAN P35610 CHEMBL2782 Acyl Coenzyme A:cholesterol Acyltransferase 1, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
SOAT1_HUMAN P35610 CHEMBL2782 Acyl Coenzyme A:cholesterol Acyltransferase 1, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z104293 Z104293 CHEMBL1907599 Integrin Alpha-4/beta-1 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z104293 Z104293 CHEMBL1907599 Integrin Alpha-4/beta-1 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
BACE1_HUMAN P56817 CHEMBL4822 Beta-secretase 1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
BRAF_HUMAN P15056 CHEMBL5145 Serine/threonine-protein Kinase B-raf, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
DPP2_HUMAN Q9UHL4 CHEMBL3976 Dipeptidyl Peptidase II, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD4_RAT P30729 CHEMBL3361 Dopamine D4 Receptor, Rat 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD4_RAT P30729 CHEMBL3361 Dopamine D4 Receptor, Rat 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
FNTA_HUMAN P49354 CHEMBL271 Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
FNTA_HUMAN P49354 CHEMBL271 Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
FNTB_HUMAN P49356 CHEMBL272 Protein Farnesyltransferase Beta Subunit, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
FNTB_HUMAN P49356 CHEMBL272 Protein Farnesyltransferase Beta Subunit, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
GHSR_HUMAN Q92847 CHEMBL4616 Ghrelin Receptor, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
GHSR_HUMAN Q92847 CHEMBL4616 Ghrelin Receptor, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
GHSR_HUMAN Q92847 CHEMBL4616 Ghrelin Receptor, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
GHSR_MOUSE Q99P50 CHEMBL3428 Ghrelin Receptor, Mouse 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
GHSR_MOUSE Q99P50 CHEMBL3428 Ghrelin Receptor, Mouse 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
GPR44_HUMAN Q9Y5Y4 CHEMBL5071 G Protein-coupled Receptor 44, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
GPR44_HUMAN Q9Y5Y4 CHEMBL5071 G Protein-coupled Receptor 44, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
GPR44_HUMAN Q9Y5Y4 CHEMBL5071 G Protein-coupled Receptor 44, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
ITK_HUMAN Q08881 CHEMBL2959 Tyrosine-protein Kinase ITK/TSK, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
ITK_HUMAN Q08881 CHEMBL2959 Tyrosine-protein Kinase ITK/TSK, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
MMP13_HUMAN P45452 CHEMBL280 Matrix Metalloproteinase 13, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
MMP13_HUMAN P45452 CHEMBL280 Matrix Metalloproteinase 13, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
MMP1_HUMAN P03956 CHEMBL332 Matrix Metalloproteinase-1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
MMP1_HUMAN P03956 CHEMBL332 Matrix Metalloproteinase-1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
MMP7_HUMAN P09237 CHEMBL4073 Matrix Metalloproteinase 7, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
MMP9_HUMAN P14780 CHEMBL321 Matrix Metalloproteinase 9, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
MMP9_HUMAN P14780 CHEMBL321 Matrix Metalloproteinase 9, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
O49150_SOLTU O49150 CHEMBL3317 5-lipoxygenase, Soltu 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PGH2_SHEEP P79208 CHEMBL4102 Cyclooxygenase-2, Sheep 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PLK3_HUMAN Q9H4B4 CHEMBL4897 Serine/threonine-protein Kinase PLK3, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PPARA_HUMAN Q07869 CHEMBL239 Peroxisome Proliferator-activated Receptor Alpha, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PPARA_HUMAN Q07869 CHEMBL239 Peroxisome Proliferator-activated Receptor Alpha, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PPARD_HUMAN Q03181 CHEMBL3979 Peroxisome Proliferator-activated Receptor Delta, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PPARD_HUMAN Q03181 CHEMBL3979 Peroxisome Proliferator-activated Receptor Delta, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q72547_9HIV1 Q72547 CHEMBL247 Human Immunodeficiency Virus Type 1 Reverse Transcriptase, 9hiv1 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q8JXU8_9HEPC Q8JXU8 CHEMBL5375 Hepatitis C Virus NS5B RNA-dependent RNA Polymerase, 9hepc 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q9ERV0_RAT Q9ERV0 CHEMBL1687686 Pkd1, Rat 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q9ERV0_RAT Q9ERV0 CHEMBL1687686 Pkd1, Rat 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
SC5A2_HUMAN P31639 CHEMBL3884 Sodium/glucose Cotransporter 2, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
SC5A2_HUMAN P31639 CHEMBL3884 Sodium/glucose Cotransporter 2, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z100081 Z100081 CHEMBL613107 PBMC (Peripheral Blood Mononuclear Cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z100750 Z100750 CHEMBL612548 Osteoclasts 1 Annotations Catalogs SMILES SDF Mol2 Flexibase