UCSF

Ghrelin Receptor, Human (641 Compounds)

Swissprot:
GHSR_HUMAN
Stitch:
GHSR_HUMAN
UniProt:
Q92847
ChEMBL:
CHEMBL4616
Reactome:
REACT_18283
REACT_14819
PDB:
GHSR

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 641 13 1 3
Binding ≤ 1μM 557 6 1 3
Functional ≤ 10μM 627 6 0 1

Reactome Network (2)

Reactome ID Description Species
REACT_18283 G alpha (q) signalling events Homo sapiens
REACT_14819 Peptide ligand-binding receptors Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
AGTR1_HUMAN P30556 CHEMBL227 Angiotensin II Type 1 Receptor, Human 1
NK1R_HUMAN P25103 CHEMBL249 Neurokinin 1 Receptor, Human 1
OXYR_HUMAN P30559 CHEMBL2049 Oxytocin Receptor, Human 1
V1AR_HUMAN P37288 CHEMBL1889 Vasopressin V1a Receptor, Human 1

Peptide ligand-binding receptors

Uniprot Swissprot Chembl Description Number Shared
AGTR1_HUMAN P30556 CHEMBL227 Angiotensin II Type 1 Receptor, Human 1
MC3R_HUMAN P41968 CHEMBL4644 Melanocortin Receptor 3, Human 6
MC4R_HUMAN P32245 CHEMBL259 Melanocortin Receptor 4, Human 7
MC5R_HUMAN P33032 CHEMBL4608 Melanocortin Receptor 5, Human 5
OPRK_HUMAN P41145 CHEMBL237 Kappa Opioid Receptor, Human 1
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
GHSR_MOUSE Q99P50 CHEMBL3428 Ghrelin Receptor, Mouse 56 1 0 0
GHSR_PIG Q95254 CHEMBL2224 Ghrelin Receptor, Pig 1 0 0 0
GHSR_RAT O08725 CHEMBL3278 Ghrelin Receptor, Rat 3 0 0 0

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
Z81011 Z81011 CHEMBL614840 Human Cell Lines 102
GHSR_MOUSE Q99P50 CHEMBL3428 Ghrelin Receptor, Mouse 56
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 43
MC4R_HUMAN P32245 CHEMBL259 Melanocortin Receptor 4, Human 7
GHSR_RAT O08725 CHEMBL3278 Ghrelin Receptor, Rat 5
MC3R_HUMAN P41968 CHEMBL4644 Melanocortin Receptor 3, Human 5
DYR_HUMAN P00374 CHEMBL202 Dihydrofolate Reductase, Human 4
GHRHR_RAT Q02644 CHEMBL3709 Growth Hormone-releasing Hormone Receptor, Rat 4
MC4R_MOUSE P56450 CHEMBL3719 Melanocortin Receptor 4, Mouse 4
MC5R_HUMAN P33032 CHEMBL4608 Melanocortin Receptor 5, Human 4
MC3R_MOUSE P33033 CHEMBL4774 Melanocortin Receptor 3, Mouse 3
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 2
MC3R_RAT P32244 CHEMBL4023 Melanocortin Receptor 3, Rat 2
MC4R_RAT P70596 CHEMBL2700 Melanocortin Receptor 4, Rat 2
Q8MHZ5_SHEEP Q8MHZ5 CHEMBL5015 Ghrelin Receptor, Sheep 2
ADRB3_HUMAN P13945 CHEMBL246 Beta-3 Adrenergic Receptor, Human 1
AGTR1_HUMAN P30556 CHEMBL227 Angiotensin II Type 1 Receptor, Human 1
GHSR_PIG Q95254 CHEMBL2224 Ghrelin Receptor, Pig 1
MSHR_MOUSE Q01727 CHEMBL4077 Melanocortin Receptor 1, Mouse 1
NK1R_HUMAN P25103 CHEMBL249 Neurokinin 1 Receptor, Human 1
OPRK_HUMAN P41145 CHEMBL237 Kappa Opioid Receptor, Human 1
OXYR_HUMAN P30559 CHEMBL2049 Oxytocin Receptor, Human 1
V1AR_HUMAN P37288 CHEMBL1889 Vasopressin V1a Receptor, Human 1

Most Common Rings