UCSF

Cathepsin D, Human (748 Compounds)

Swissprot:
CATD_HUMAN
Stitch:
CATD_HUMAN
UniProt:
P07339
ChEMBL:
CHEMBL2581
Reactome:
REACT_150401
REACT_147707
REACT_121399
PDB:
1LYA (DOCK)
1LYB (DOCK)
1LYW (DOCK)
CTSD

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 748 1 0 0
Binding ≤ 1μM 370 0 0 0
Functional ≤ 10μM 11 0 0 0

Reactome Network (3)

Reactome ID Description Species
REACT_150401 Collagen degradation Homo sapiens
REACT_147707 Metabolism of Angiotensinogen to Angiotensins Homo sapiens
REACT_121399 MHC class II antigen presentation Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
ADAM9_HUMAN Q13443 CHEMBL5982 ADAM9, Human 1
CATB_HUMAN P07858 CHEMBL4072 Cathepsin B, Human 1
CATL1_HUMAN P07711 CHEMBL3837 Cathepsin L, Human 1

Metabolism of Angiotensinogen to Angiotensins

Uniprot Swissprot Chembl Description Number Shared
RENI_HUMAN P00797 CHEMBL286 Renin, Human 62

MHC class II antigen presentation

Uniprot Swissprot Chembl Description Number Shared
CATB_HUMAN P07858 CHEMBL4072 Cathepsin B, Human 1
CATE_HUMAN P14091 CHEMBL3092 Cathepsin E, Human 38
CATL1_HUMAN P07711 CHEMBL3837 Cathepsin L, Human 1
CATS_HUMAN P25774 CHEMBL2954 Cathepsin S, Human 2
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
CATD_BOVIN P80209 CHEMBL4106 Cathepsin D, Bovin 305 0 0 0

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
BACE1_HUMAN P56817 CHEMBL4822 Beta-secretase 1, Human 452
BACE2_HUMAN Q9Y5Z0 CHEMBL2525 Beta Secretase 2, Human 226
PLM2_PLAFA P46925 CHEMBL4414 Plasmepsin 2, Plafa 158
RENI_HUMAN P00797 CHEMBL286 Renin, Human 62
PEPC_HUMAN P20142 CHEMBL2136 Pepsinogen C, Human 39
PLM1_PLAFA P39898 CHEMBL4687 Plasmepsin 1, Plafa 39
CATE_HUMAN P14091 CHEMBL3092 Cathepsin E, Human 38
PEPA_HUMAN P00790 CHEMBL3295 Pepsin A, Human 34
PEPA_PIG P00791 CHEMBL2714 Pepsin A, Pig 25
Q72874_9HIV1 Q72874 CHEMBL243 Human Immunodeficiency Virus Type 1 Protease, 9hiv1 7
CATS_HUMAN P25774 CHEMBL2954 Cathepsin S, Human 2
Q4U254_9ENTO Q4U254 CHEMBL2857 Human Rhinovirus A Protease, 9ento 2
TP4A1_HUMAN Q93096 CHEMBL1075169 Protein Tyrosine Phosphatase Type IVA 1, Human 2
TP4A2_HUMAN Q12974 CHEMBL1075105 Protein Tyrosine Phosphatase Type IVA 2, Human 2
TP4A3_HUMAN O75365 CHEMBL4162 Protein-tyrosine Phosphatase 4A3, Human 2
ADAM9_HUMAN Q13443 CHEMBL5982 ADAM9, Human 1
CAN1_HUMAN P07384 CHEMBL3891 Calpain 1, Human 1
CATB_HUMAN P07858 CHEMBL4072 Cathepsin B, Human 1
CATD_BOVIN P80209 CHEMBL4106 Cathepsin D, Bovin 1
CATL1_HUMAN P07711 CHEMBL3837 Cathepsin L, Human 1
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 1
Q95WR6_LEIDO Q95WR6 CHEMBL4751 Cysteine Protease, Leido 1
Q9Y006_PLAFA Q9Y006 CHEMBL6075 HAP Protein (Putative Aspartic Proteinase), Plafa 1
RENI_RAT P08424 CHEMBL2322 Renin, Rat 1
Z50607 Z50607 CHEMBL378 Human Immunodeficiency Virus 1 1
Z80295 Z80295 CHEMBL388 MT4 (Lymphocytes) 1

Most Common Rings