UCSF

SF268 (139 Compounds)

Swissprot:
Z80466
Stitch:
Z80466
UniProt:
Z80466
ChEMBL:
CHEMBL614907

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Functional ≤ 10μM 139 20 26 7
ADME/T ≤ 10μM 0 0 0 0

Reactome Network (0)

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
Z81024 Z81024 CHEMBL396 NCI-H460 (Non-small Cell Lung Carcinoma) 107
Z80186 Z80186 CHEMBL385 K562 (Erythroleukemia Cells) 60
Z80493 Z80493 CHEMBL614925 SK-OV-3 (Ovarian Carcinoma Cells) 58
Z80224 Z80224 CHEMBL387 MCF7 (Breast Carcinoma Cells) 54
Z81115 Z81115 CHEMBL398 KB (Squamous Cell Carcinoma) 53
Z80156 Z80156 CHEMBL383 HL-60 (Promyeloblast Leukemia Cells) 49
Z80485 Z80485 CHEMBL614919 SK-MEL-28 (Melanoma Cells) 43
Z80166 Z80166 CHEMBL384 HT-29 (Colon Adenocarcinoma Cells) 20
Z80928 Z80928 CHEMBL394 HCT-116 (Colon Carcinoma Cells) 18
Z80193 Z80193 CHEMBL386 L1210 (Lymphocytic Leukemia Cells) 16
Z80362 Z80362 CHEMBL389 P388 (Lymphoma Cells) 15
Z80390 Z80390 CHEMBL390 PC-3 (Prostate Carcinoma Cells) 15
Z81252 Z81252 CHEMBL400 MDA-MB-231 (Breast Adenocarcinoma Cells) 15
Z81335 Z81335 CHEMBL612263 HCT-15 (Colon Adenocarcinoma Cells) 15
Z80682 Z80682 CHEMBL392 A549 (Lung Carcinoma Cells) 14
Z50677 Z50677 CHEMBL613758 Human Immunodeficiency Virus 12
Z81072 Z81072 CHEMBL397 Jurkat (Acute Leukemic T-cells) 12
Z81247 Z81247 CHEMBL399 HeLa (Cervical Adenocarcinoma Cells) 11
Z80125 Z80125 CHEMBL613508 DU-145 (Prostate Carcinoma) 10
Z80354 Z80354 CHEMBL614213 OVCAR-3 (Ovarian Adenocarcinoma Cells) 10
Z80427 Z80427 CHEMBL614879 RKO (Colon Carcinoma) 9
Z81245 Z81245 CHEMBL614697 MDA-MB-435 (Breast Carcinoma Cells) 9
Z80712 Z80712 CHEMBL614361 T47D (Breast Carcinoma Cells) 8
Z81020 Z81020 CHEMBL395 HepG2 (Hepatoblastoma Cells) 8
Z81331 Z81331 CHEMBL612262 SW-620 (Colon Adenocarcinoma Cells) 8
Z80025 Z80025 CHEMBL614519 ACHN (Renal Adenocarcinoma Cells) 7
Z80526 Z80526 CHEMBL612544 SW480 (Colon Adenocarcinoma Cells) 7
Z81170 Z81170 CHEMBL612518 LNCaP (Prostate Carcinoma) 7
Z80214 Z80214 CHEMBL614317 M14 (Melanoma Cells) 6
Z80874 Z80874 CHEMBL393 CEM (T-cell Leukemia) 6
Z80889 Z80889 CHEMBL614803 NCI-H322M (Non-small Cell Lung Carcinoma Cells) 6
Z81034 Z81034 CHEMBL614004 A2780 (Ovarian Carcinoma Cells) 6
Z81281 Z81281 CHEMBL614997 NCI-H23 (Non-small Cell Lung Carcinoma Cells) 6
Z80035 Z80035 CHEMBL381 B16 (Melanoma Cells) 5
Z80064 Z80064 CHEMBL382 CCRF-CEM (T-cell Leukemia) 5
Z80164 Z80164 CHEMBL614580 HT-1080 (Fibrosarcoma Cells) 5
Z80188 Z80188 CHEMBL614590 KB 3-1 (Cervical Epithelial Carcinoma Cells) 5
Z80482 Z80482 CHEMBL614917 SK-MEL-2 (Melanoma Cells) 5
Z80559 Z80559 CHEMBL615021 U251 5
Z81054 Z81054 CHEMBL613977 SF-268 (Glioblastoma Cells) 5
Z81280 Z81280 CHEMBL614740 NCI-H226 (Non-small Cell Lung Carcinoma Cells) 5
Z81283 Z81283 CHEMBL614387 NCI-H522 (Non-small Cell Lung Carcinoma Cells) 5
Z103205 Z103205 CHEMBL1075390 A431 4
Z80021 Z80021 CHEMBL614516 A498 (Renal Carcinoma Cells) 4
Z80088 Z80088 CHEMBL613853 CHO (Ovarian Cells) 4
Z80192 Z80192 CHEMBL614709 KM12 (Colon Adenocarcinoma Cells) 4
Z80211 Z80211 CHEMBL614721 LoVo (Colon Adenocarcinoma Cells) 4
Z80244 Z80244 CHEMBL614335 MDA-MB-468 (Breast Adenocarcinoma) 4
Z80255 Z80255 CHEMBL613827 MES-SA/DxS (Uterine Sarcoma Cells) 4
Z80269 Z80269 CHEMBL614354 MKN-45 (Gastric Adenocarcinoma Cells) 4
Z80285 Z80285 CHEMBL614177 MOLT-4 (Acute T-lymphoblastic Leukemia Cells) 4
Z80364 Z80364 CHEMBL614218 P388/ADR (Lymphoma Cells) 4
Z80414 Z80414 CHEMBL614628 Raji (B-lymphoblastic Cells) 4
Z80475 Z80475 CHEMBL613834 SK-BR-3 (Breast Adenocarcinoma) 4
Z80498 Z80498 CHEMBL614054 SN12C (Renal Carcinoma Cells) 4
Z80532 Z80532 CHEMBL614774 T-24 (Bladder Carcinoma Cells) 4
Z81017 Z81017 CHEMBL614647 WiDr (Colon Adenocarcinoma Cells) 4
Z81248 Z81248 CHEMBL614021 Malme-3M (Melanoma Cells) 4
TBB1_HUMAN Q9H4B7 CHEMBL1915 Tubulin Beta-1 Chain, Human 3
TOP1_HUMAN P11387 CHEMBL1781 DNA Topoisomerase I, Human 3
TOP1_MOUSE Q04750 CHEMBL2814 DNA Topoisomerase I, Mouse 3
TOP2A_HUMAN P11388 CHEMBL1806 DNA Topoisomerase II Alpha, Human 3
TOP2A_MOUSE Q01320 CHEMBL3586 DNA Topoisomerase II Alpha, Mouse 3
TOP2B_HUMAN Q02880 CHEMBL3396 DNA Topoisomerase II Beta, Human 3
TOP2B_MOUSE Q64511 CHEMBL5564 DNA Topoisomerase II Beta, Mouse 3
Z103196 Z103196 CHEMBL1075381 22RV1 3
Z103203 Z103203 CHEMBL1075388 A375 3
Z50425 Z50425 CHEMBL364 Plasmodium Falciparum 3
Z50587 Z50587 CHEMBL372 Homo Sapiens 3
Z50643 Z50643 CHEMBL379 Hepatitis C Virus 3
Z80026 Z80026 CHEMBL613860 AGS (Gastric Adenocarcinoma Cells) 3
Z80054 Z80054 CHEMBL614058 Caco-2 (Colon Adenocarcinoma Cells) 3
Z80068 Z80068 CHEMBL614542 CCRF-SB (Lymphoblastic Leukemia Cells) 3
Z80145 Z80145 CHEMBL614045 H69 3
Z80227 Z80227 CHEMBL614324 MCF7-ADR (Breast Carcinoma Cells) 3
Z80240 Z80240 CHEMBL614129 MDA-MB-361 3
Z80254 Z80254 CHEMBL614343 MES-SA (Uterine Sarcoma Cells) 3
Z80295 Z80295 CHEMBL388 MT4 (Lymphocytes) 3
Z80488 Z80488 CHEMBL614922 SK-MEL-5 (Melanoma Cells) 3
Z80495 Z80495 CHEMBL614927 SK-VLB 3
Z80548 Z80548 CHEMBL614245 THP-1 (Acute Monocytic Leukemia Cells) 3
Z80561 Z80561 CHEMBL615023 U2OS (Osteosarcoma Cells) 3
Z80563 Z80563 CHEMBL615025 U-373 MG ( Glioblastoma Cells) 3
Z80583 Z80583 CHEMBL391 Vero (Kidney Cells) 3
Z80608 Z80608 CHEMBL614393 ZR-75-1 (Breast Carcinoma Cells) 3
Z80697 Z80697 CHEMBL614279 Bel-7402 (Hepatoma Cells) 3
Z80711 Z80711 CHEMBL613829 NCI/ADR-RES (Breast Carcinoma Cells) 3
Z80726 Z80726 CHEMBL614367 TRAMP-C1A (Prostate Carcinoma Cells) 3
Z80730 Z80730 CHEMBL614368 C2D Cell Line 3
Z80731 Z80731 CHEMBL613541 C2G Cell Line 3
Z80732 Z80732 CHEMBL614369 TRAMP-C2H (Prostate Carcinoma Cells) 3
Z80784 Z80784 CHEMBL614462 Col2 (Colon Carcinoma Cells) 3
Z80819 Z80819 CHEMBL614484 J774.2 3
Z80852 Z80852 CHEMBL614069 A-431 (Epidermoid Carcinoma Cells) 3
Z80896 Z80896 CHEMBL614805 NCI-H69 (Small Cell Lung Carcinoma Cells) 3
Z81133 Z81133 CHEMBL614000 L1210 (1565) 3
Z81134 Z81134 CHEMBL614650 L2987 (Lung Adenocarcinoma Cells) 3
Z81160 Z81160 CHEMBL614088 Lewis Lung Carcinoma Cell Line 3
Z81164 Z81164 CHEMBL614091 LL Cell Line 3
Z81184 Z81184 CHEMBL614096 LOX IMVI (Melanoma Cells) 3
Z81244 Z81244 CHEMBL614123 J774 (Macrophage Cells) 3
TBA1A_RAT P68370 CHEMBL4139 Tubulin Alpha-1 Chain, Rat 2
TBB3_HUMAN Q13509 CHEMBL2597 Tubulin Beta-3 Chain, Human 2
TBB4A_HUMAN P04350 CHEMBL3838 Tubulin Beta-4 Chain, Human 2
TBB4B_HUMAN P68371 CHEMBL1848 Tubulin Beta-2 Chain, Human 2
TBB8_HUMAN Q3ZCM7 CHEMBL4024 Tubulin Beta-8 Chain, Human 2
Z100733 Z100733 CHEMBL613866 CT26 (Colon Carcinoma Cells) 2
Z103219 Z103219 CHEMBL1075404 Ca9-22 2
Z50347 Z50347 CHEMBL361 Saccharomyces Cerevisiae 2
Z50590 Z50590 CHEMBL613488 Sus Scrofa 2
Z80008 Z80008 CHEMBL612565 5637 (Epithelial Bladder Carcinoma Cells) 2
Z80017 Z80017 CHEMBL614023 A2780cisR (Cisplatin-resistant Ovarian Carcinoma Cells) 2
Z80018 Z80018 CHEMBL613859 A-375 (Malignant Melanoma Cells) 2
Z80039 Z80039 CHEMBL614526 BGC-823 (Stomach Adenocarcinoma Cells) 2
Z80052 Z80052 CHEMBL614533 C8166 (Leukemic T-cells) 2
Z80092 Z80092 CHEMBL614031 CHO-K1 (Ovarian Cells) 2
Z80105 Z80105 CHEMBL613854 COR-L23 (Lung Carcinoma Cells) 2
Z80114 Z80114 CHEMBL614281 Daudi (Burkitts Lymphoma Cells) 2
Z80120 Z80120 CHEMBL614285 DLD-1 (Colon Adenocarcinoma Cells) 2
Z80126 Z80126 CHEMBL614289 DuPro 2
Z80138 Z80138 CHEMBL614036 G-361 (Melanoma Cells) 2
Z80175 Z80175 CHEMBL614585 IMR-32 (Neuroblastoma Cells) 2
Z80243 Z80243 CHEMBL614334 MDA-MB-453 (Breast Adenocarcinoma Cells) 2
Z80267 Z80267 CHEMBL614352 MKN-1 2
Z80291 Z80291 CHEMBL614181 MRC5 (Embryonic Lung Fibroblast Cells) 2
Z80322 Z80322 CHEMBL614135 NCI-H358 (Lung Carcinama Cells) 2
Z80330 Z80330 CHEMBL614197 NCI-N87 2
Z80367 Z80367 CHEMBL614220 P388/S 2
Z80389 Z80389 CHEMBL614140 PC-14 2
Z80433 Z80433 CHEMBL614882 RPMI-8226 (Multiple Myeloma Cells) 2
Z80441 Z80441 CHEMBL614889 RXF 944 2
Z80468 Z80468 CHEMBL614908 SF-295 (Glioblastoma Cells) 2
Z80472 Z80472 CHEMBL612542 SiHa (Cervical Squamous Cell Carcinoma) 2
Z80477 Z80477 CHEMBL614912 SK_HEP1 (Hepatoma Cells) 2
Z80479 Z80479 CHEMBL614914 SK-MEL (Melanoma Cells) 2
Z80481 Z80481 CHEMBL614916 SK-MEL-1 (Metastatic Melanoma Cells) 2
Z80490 Z80490 CHEMBL614923 SK-MES-1 2
Z80491 Z80491 CHEMBL614163 SK-N-MC (Neuroepithelioma Cells) 2
Z80492 Z80492 CHEMBL614924 SK-N-SH (Neuroblastoma Cells) 2
Z80503 Z80503 CHEMBL614931 SNU1 2
Z80509 Z80509 CHEMBL614935 SNU-638 (Gastric Carcinoma Cells) 2
Z80560 Z80560 CHEMBL615022 U-251 (Glioma Cells) 2
Z80565 Z80565 CHEMBL614247 U-87 MG (Glioblastoma Cells) 2
Z80574 Z80574 CHEMBL612799 UMUC3 2
Z80581 Z80581 CHEMBL614248 VA13 2
Z80595 Z80595 CHEMBL612810 WIL2-NS (Lymphoblastoid Cells) 2
Z80600 Z80600 CHEMBL613533 XF498 (Glioma Cells) 2
Z80640 Z80640 CHEMBL613102 786-0 (Renal Carcinoma Cells) 2
Z80661 Z80661 CHEMBL614567 A704 (Renal Carcinoma Cells) 2
Z80735 Z80735 CHEMBL614739 C38 (Colon Carcinoma) 2
Z80768 Z80768 CHEMBL614455 CH1 (Ovarian Carcinoma Cells) 2
Z80801 Z80801 CHEMBL614151 CRL-7065 Cell Line 2
Z80846 Z80846 CHEMBL614493 F460pv8/eto Cell Line 2
Z80887 Z80887 CHEMBL614802 H2981 Cell Line 2
Z80936 Z80936 CHEMBL614818 HEK293 (Embryonic Kidney Fibroblasts) 2
Z80943 Z80943 CHEMBL614819 HEL 299 2
Z80945 Z80945 CHEMBL614735 HEp-2 (Laryngeal Carcinoma Cells) 2
Z81005 Z81005 CHEMBL614839 HTB-54 Cell Line 2
Z81006 Z81006 CHEMBL612259 Human Breast 401NL Tumor Cell Line 2
Z81025 Z81025 CHEMBL613890 Human Lung LXF 529L Tumor Cell Line 2
Z81026 Z81026 CHEMBL614689 Human Lung LXF 629L Tumor Cell Line 2
Z81028 Z81028 CHEMBL613892 Human Melanoma Cell Line 2
Z81043 Z81043 CHEMBL613969 N592 2
Z81101 Z81101 CHEMBL614010 KBM-3 Cell Line 2
Z81102 Z81102 CHEMBL613994 KBM-3/DOX Cell Line 2
Z81167 Z81167 CHEMBL614093 LLTC Cell Line 2
Z81201 Z81201 CHEMBL614643 HOP-62 (Non-small Cell Lung Carcinoma Cells) 2
Z81211 Z81211 CHEMBL614109 LXFL529 Cell Line 2
Z81246 Z81246 CHEMBL614078 MDA-N (Breast Carcinoma Cells) 2
Z81257 Z81257 CHEMBL614732 MEL-AC Cell Line 2
Z81261 Z81261 CHEMBL614127 UACC-375 2
Z81277 Z81277 CHEMBL613287 NCI-N417 2
Z81284 Z81284 CHEMBL614999 NCI-H647 2
Z81341 Z81341 CHEMBL614310 Tumor Cell Lines 2
CHK1_HUMAN O14757 CHEMBL4630 Serine/threonine-protein Kinase Chk1, Human 1
Q862F3_BOVIN Q862F3 CHEMBL4262 Tubulin Alpha Chain, Bovin 1
Q862L2_BOVIN Q862L2 CHEMBL3752 Tubulin Alpha-1 Chain, Bovin 1
SSR1_HUMAN P30872 CHEMBL1917 Somatostatin Receptor 1, Human 1
SSR2_HUMAN P30874 CHEMBL1804 Somatostatin Receptor 2, Human 1
SSR3_HUMAN P32745 CHEMBL2028 Somatostatin Receptor 3, Human 1
SSR4_HUMAN P31391 CHEMBL1853 Somatostatin Receptor 4, Human 1
SSR5_HUMAN P35346 CHEMBL1792 Somatostatin Receptor 5, Human 1
TBA1A_PIG P02550 CHEMBL3658 Tubulin Alpha Chain, Pig 1
TBA4A_HUMAN P68366 CHEMBL2070 Tubulin Alpha-1 Chain, Human 1
TBB2B_BOVIN Q6B856 CHEMBL3394 Tubulin Beta Chain, Bovin 1
TBB5_HUMAN P07437 CHEMBL5444 Tubulin Beta-5 Chain, Human 1
Z100501 Z100501 CHEMBL613290 Lu1 (Lung Carcinoma Cells) 1
Z100515 Z100515 CHEMBL612595 HPAC (Pancreatic Adenocarcinoma) 1
Z100752 Z100752 CHEMBL612568 Renca (Renal Carcinoma Cells) 1
Z100757 Z100757 CHEMBL612570 SW1573 (Lung Carcinoma Cells) 1
Z101682 Z101682 CHEMBL613915 BK Polyomavirus 1
Z101973 Z101973 CHEMBL613240 Paracentrotus Lividus 1
Z103359 Z103359 CHEMBL1075544 NCI-H661 1
Z103393 Z103393 CHEMBL1075578 SK-N-AS 1
Z103407 Z103407 CHEMBL1075592 SW1990 1
Z103408 Z103408 CHEMBL1075593 SW626 1
Z103413 Z103413 CHEMBL1075598 SW948 1
Z50460 Z50460 CHEMBL612879 Leishmania Major 1
Z50515 Z50515 CHEMBL370 Human Herpesvirus 2 1
Z50602 Z50602 CHEMBL377 Human Herpesvirus 1 1
Z50607 Z50607 CHEMBL378 Human Immunodeficiency Virus 1 1
Z80002 Z80002 CHEMBL614075 1A9 (Ovarian Adenocarcinoma Cells) 1
Z80012 Z80012 CHEMBL614512 A 172 (Glioblastoma Cells) 1
Z80014 Z80014 CHEMBL614514 A204 (Rhabdomyosarcoma Cells) 1
Z80019 Z80019 CHEMBL614515 A-427 (Lung Carcinoma Cells) 1
Z80024 Z80024 CHEMBL614518 A9 (Fibroblast Cells) 1
Z80048 Z80048 CHEMBL614530 BXPC-3 (Pancreatic Adenocarcinoma Cells) 1
Z80056 Z80056 CHEMBL613852 CAKI-2 (Renal Carcinoma Cells) 1
Z80060 Z80060 CHEMBL614536 CAPAN-1 (Pancreatic Adenocarcinoma Cells) 1
Z80067 Z80067 CHEMBL614541 CCRF-HSB-2 (T-cell Leukemia Cells) 1
Z80076 Z80076 CHEMBL614548 CEM-SS (T-cell Leukemia) 1
Z80096 Z80096 CHEMBL614559 CHO-TAX 5-6 1
Z80097 Z80097 CHEMBL614560 CHO-VV 3-2 1
Z80099 Z80099 CHEMBL614561 COLO 205 (Colon Adenocarcinoma Cells) 1
Z80100 Z80100 CHEMBL614257 COLO 320 (Colon Adenocarcinoma Cells) 1
Z80115 Z80115 CHEMBL612702 DC3F 1
Z80132 Z80132 CHEMBL614293 EL4 (Thymoma Cells) 1
Z80134 Z80134 CHEMBL614295 EVSA-T 1
Z80152 Z80152 CHEMBL613510 HCT-8 (Ileocecal Adenocarcinoma) 1
Z80316 Z80316 CHEMBL614771 NCI-H128 1
Z80335 Z80335 CHEMBL614200 NHDF 1
Z80342 Z80342 CHEMBL612554 NSCLC (Non-small Cell Lung Carcinoma Cells) 1
Z80372 Z80372 CHEMBL614224 P388CPT5 1
Z80429 Z80429 CHEMBL614881 RPMI 6410 1
Z80457 Z80457 CHEMBL614901 SCC-25 1
Z80478 Z80478 CHEMBL614913 SK-LU-1 1
Z80500 Z80500 CHEMBL614930 SNB-7 1
Z80525 Z80525 CHEMBL614055 SW48 1
Z80566 Z80566 CHEMBL612794 U-937 (Histiocytic Lymphoma Cells) 1
Z80571 Z80571 CHEMBL612797 UCLA P-3 1
Z80585 Z80585 CHEMBL613532 WALKER 1
Z80606 Z80606 CHEMBL612816 YOSHIDA (Sarcoma Cells) 1
Z80623 Z80623 CHEMBL612911 Panel (56 Tumour Cell Lines) 1
Z80647 Z80647 CHEMBL613103 833K Cell Line 1
Z80678 Z80678 CHEMBL614270 AMML Cell Line 1
Z80702 Z80702 CHEMBL613537 BG-1 Cell Line 1
Z80720 Z80720 CHEMBL614365 Burkitts Lymphoma Cells 1
Z80742 Z80742 CHEMBL614657 C6 (Glioma Cells) 1
Z80751 Z80751 CHEMBL614379 Caov-3 Cell Line 1
Z80777 Z80777 CHEMBL614800 CML/BC Cell Line 1
Z80799 Z80799 CHEMBL612517 RPMI 8402 (Pre-T-lymphoblastoid Cells) 1
Z80898 Z80898 CHEMBL614785 NCI-H928 1
Z80930 Z80930 CHEMBL614817 HEC-1B Cell Line 1
Z80957 Z80957 CHEMBL614734 HMEC (Microvascular Endothelial Cells) 1
Z81077 Z81077 CHEMBL613989 KATO III Cell Line 1
Z81080 Z81080 CHEMBL613991 KATO-III Cell Line 1
Z81084 Z81084 CHEMBL613992 KB VCR R 1
Z81159 Z81159 CHEMBL614087 Lewis Cell Line 1
Z81166 Z81166 CHEMBL614092 LLC Cell Line 1
Z81187 Z81187 CHEMBL614098 LT12 Tumor Cell Line 1
Z81192 Z81192 CHEMBL614101 PC-8 1
Z81193 Z81193 CHEMBL614102 PC-9 1
Z81227 Z81227 CHEMBL614116 M-19 Cell Line 1

Most Common Rings