UCSF

MDA-MB-453 (Breast Adenocarcinoma Cells) (45 Compounds)

Swissprot:
Z80243
Stitch:
Z80243
UniProt:
Z80243
ChEMBL:
CHEMBL614334

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Functional ≤ 10μM 45 22 5 3

Reactome Network (0)

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
ANDR_HUMAN P10275 CHEMBL1871 Androgen Receptor, Human 33
Z80244 Z80244 CHEMBL614335 MDA-MB-468 (Breast Adenocarcinoma) 4
Z81170 Z81170 CHEMBL612518 LNCaP (Prostate Carcinoma) 4
PRGR_HUMAN P06401 CHEMBL208 Progesterone Receptor, Human 3
Z80224 Z80224 CHEMBL387 MCF7 (Breast Carcinoma Cells) 3
Z80354 Z80354 CHEMBL614213 OVCAR-3 (Ovarian Adenocarcinoma Cells) 3
Z80482 Z80482 CHEMBL614917 SK-MEL-2 (Melanoma Cells) 3
Z80485 Z80485 CHEMBL614919 SK-MEL-28 (Melanoma Cells) 3
Z80682 Z80682 CHEMBL392 A549 (Lung Carcinoma Cells) 3
Z80712 Z80712 CHEMBL614361 T47D (Breast Carcinoma Cells) 3
Z80928 Z80928 CHEMBL394 HCT-116 (Colon Carcinoma Cells) 3
Z81020 Z81020 CHEMBL395 HepG2 (Hepatoblastoma Cells) 3
Z81252 Z81252 CHEMBL400 MDA-MB-231 (Breast Adenocarcinoma Cells) 3
TOP1_HUMAN P11387 CHEMBL1781 DNA Topoisomerase I, Human 2
TOP1_MOUSE Q04750 CHEMBL2814 DNA Topoisomerase I, Mouse 2
TOP2A_HUMAN P11388 CHEMBL1806 DNA Topoisomerase II Alpha, Human 2
TOP2A_MOUSE Q01320 CHEMBL3586 DNA Topoisomerase II Alpha, Mouse 2
TOP2B_HUMAN Q02880 CHEMBL3396 DNA Topoisomerase II Beta, Human 2
TOP2B_MOUSE Q64511 CHEMBL5564 DNA Topoisomerase II Beta, Mouse 2
Z103203 Z103203 CHEMBL1075388 A375 2
Z103205 Z103205 CHEMBL1075390 A431 2
Z103219 Z103219 CHEMBL1075404 Ca9-22 2
Z50347 Z50347 CHEMBL361 Saccharomyces Cerevisiae 2
Z50587 Z50587 CHEMBL372 Homo Sapiens 2
Z50643 Z50643 CHEMBL379 Hepatitis C Virus 2
Z80008 Z80008 CHEMBL612565 5637 (Epithelial Bladder Carcinoma Cells) 2
Z80017 Z80017 CHEMBL614023 A2780cisR (Cisplatin-resistant Ovarian Carcinoma Cells) 2
Z80018 Z80018 CHEMBL613859 A-375 (Malignant Melanoma Cells) 2
Z80021 Z80021 CHEMBL614516 A498 (Renal Carcinoma Cells) 2
Z80025 Z80025 CHEMBL614519 ACHN (Renal Adenocarcinoma Cells) 2
Z80026 Z80026 CHEMBL613860 AGS (Gastric Adenocarcinoma Cells) 2
Z80035 Z80035 CHEMBL381 B16 (Melanoma Cells) 2
Z80039 Z80039 CHEMBL614526 BGC-823 (Stomach Adenocarcinoma Cells) 2
Z80052 Z80052 CHEMBL614533 C8166 (Leukemic T-cells) 2
Z80054 Z80054 CHEMBL614058 Caco-2 (Colon Adenocarcinoma Cells) 2
Z80064 Z80064 CHEMBL382 CCRF-CEM (T-cell Leukemia) 2
Z80068 Z80068 CHEMBL614542 CCRF-SB (Lymphoblastic Leukemia Cells) 2
Z80088 Z80088 CHEMBL613853 CHO (Ovarian Cells) 2
Z80092 Z80092 CHEMBL614031 CHO-K1 (Ovarian Cells) 2
Z80105 Z80105 CHEMBL613854 COR-L23 (Lung Carcinoma Cells) 2
Z80114 Z80114 CHEMBL614281 Daudi (Burkitts Lymphoma Cells) 2
Z80125 Z80125 CHEMBL613508 DU-145 (Prostate Carcinoma) 2
Z80126 Z80126 CHEMBL614289 DuPro 2
Z80138 Z80138 CHEMBL614036 G-361 (Melanoma Cells) 2
Z80145 Z80145 CHEMBL614045 H69 2
Z80156 Z80156 CHEMBL383 HL-60 (Promyeloblast Leukemia Cells) 2
Z80164 Z80164 CHEMBL614580 HT-1080 (Fibrosarcoma Cells) 2
Z80166 Z80166 CHEMBL384 HT-29 (Colon Adenocarcinoma Cells) 2
Z80175 Z80175 CHEMBL614585 IMR-32 (Neuroblastoma Cells) 2
Z80186 Z80186 CHEMBL385 K562 (Erythroleukemia Cells) 2
Z80188 Z80188 CHEMBL614590 KB 3-1 (Cervical Epithelial Carcinoma Cells) 2
Z80193 Z80193 CHEMBL386 L1210 (Lymphocytic Leukemia Cells) 2
Z80211 Z80211 CHEMBL614721 LoVo (Colon Adenocarcinoma Cells) 2
Z80214 Z80214 CHEMBL614317 M14 (Melanoma Cells) 2
Z80227 Z80227 CHEMBL614324 MCF7-ADR (Breast Carcinoma Cells) 2
Z80240 Z80240 CHEMBL614129 MDA-MB-361 2
Z80254 Z80254 CHEMBL614343 MES-SA (Uterine Sarcoma Cells) 2
Z80255 Z80255 CHEMBL613827 MES-SA/DxS (Uterine Sarcoma Cells) 2
Z80267 Z80267 CHEMBL614352 MKN-1 2
Z80269 Z80269 CHEMBL614354 MKN-45 (Gastric Adenocarcinoma Cells) 2
Z80285 Z80285 CHEMBL614177 MOLT-4 (Acute T-lymphoblastic Leukemia Cells) 2
Z80291 Z80291 CHEMBL614181 MRC5 (Embryonic Lung Fibroblast Cells) 2
Z80295 Z80295 CHEMBL388 MT4 (Lymphocytes) 2
Z80322 Z80322 CHEMBL614135 NCI-H358 (Lung Carcinama Cells) 2
Z80330 Z80330 CHEMBL614197 NCI-N87 2
Z80362 Z80362 CHEMBL389 P388 (Lymphoma Cells) 2
Z80364 Z80364 CHEMBL614218 P388/ADR (Lymphoma Cells) 2
Z80367 Z80367 CHEMBL614220 P388/S 2
Z80389 Z80389 CHEMBL614140 PC-14 2
Z80390 Z80390 CHEMBL390 PC-3 (Prostate Carcinoma Cells) 2
Z80414 Z80414 CHEMBL614628 Raji (B-lymphoblastic Cells) 2
Z80433 Z80433 CHEMBL614882 RPMI-8226 (Multiple Myeloma Cells) 2
Z80441 Z80441 CHEMBL614889 RXF 944 2
Z80466 Z80466 CHEMBL614907 SF268 2
Z80468 Z80468 CHEMBL614908 SF-295 (Glioblastoma Cells) 2
Z80472 Z80472 CHEMBL612542 SiHa (Cervical Squamous Cell Carcinoma) 2
Z80475 Z80475 CHEMBL613834 SK-BR-3 (Breast Adenocarcinoma) 2
Z80477 Z80477 CHEMBL614912 SK_HEP1 (Hepatoma Cells) 2
Z80479 Z80479 CHEMBL614914 SK-MEL (Melanoma Cells) 2
Z80481 Z80481 CHEMBL614916 SK-MEL-1 (Metastatic Melanoma Cells) 2
Z80490 Z80490 CHEMBL614923 SK-MES-1 2
Z80491 Z80491 CHEMBL614163 SK-N-MC (Neuroepithelioma Cells) 2
Z80492 Z80492 CHEMBL614924 SK-N-SH (Neuroblastoma Cells) 2
Z80493 Z80493 CHEMBL614925 SK-OV-3 (Ovarian Carcinoma Cells) 2
Z80495 Z80495 CHEMBL614927 SK-VLB 2
Z80503 Z80503 CHEMBL614931 SNU1 2
Z80509 Z80509 CHEMBL614935 SNU-638 (Gastric Carcinoma Cells) 2
Z80526 Z80526 CHEMBL612544 SW480 (Colon Adenocarcinoma Cells) 2
Z80532 Z80532 CHEMBL614774 T-24 (Bladder Carcinoma Cells) 2
Z80559 Z80559 CHEMBL615021 U251 2
Z80560 Z80560 CHEMBL615022 U-251 (Glioma Cells) 2
Z80563 Z80563 CHEMBL615025 U-373 MG ( Glioblastoma Cells) 2
Z80565 Z80565 CHEMBL614247 U-87 MG (Glioblastoma Cells) 2
Z80574 Z80574 CHEMBL612799 UMUC3 2
Z80581 Z80581 CHEMBL614248 VA13 2
Z80583 Z80583 CHEMBL391 Vero (Kidney Cells) 2
Z80595 Z80595 CHEMBL612810 WIL2-NS (Lymphoblastoid Cells) 2
Z80600 Z80600 CHEMBL613533 XF498 (Glioma Cells) 2
Z80608 Z80608 CHEMBL614393 ZR-75-1 (Breast Carcinoma Cells) 2
Z80661 Z80661 CHEMBL614567 A704 (Renal Carcinoma Cells) 2
Z80697 Z80697 CHEMBL614279 Bel-7402 (Hepatoma Cells) 2
Z80726 Z80726 CHEMBL614367 TRAMP-C1A (Prostate Carcinoma Cells) 2
Z80730 Z80730 CHEMBL614368 C2D Cell Line 2
Z80731 Z80731 CHEMBL613541 C2G Cell Line 2
Z80732 Z80732 CHEMBL614369 TRAMP-C2H (Prostate Carcinoma Cells) 2
Z80735 Z80735 CHEMBL614739 C38 (Colon Carcinoma) 2
Z80768 Z80768 CHEMBL614455 CH1 (Ovarian Carcinoma Cells) 2
Z80784 Z80784 CHEMBL614462 Col2 (Colon Carcinoma Cells) 2
Z80801 Z80801 CHEMBL614151 CRL-7065 Cell Line 2
Z80819 Z80819 CHEMBL614484 J774.2 2
Z80846 Z80846 CHEMBL614493 F460pv8/eto Cell Line 2
Z80852 Z80852 CHEMBL614069 A-431 (Epidermoid Carcinoma Cells) 2
Z80874 Z80874 CHEMBL393 CEM (T-cell Leukemia) 2
Z80887 Z80887 CHEMBL614802 H2981 Cell Line 2
Z80889 Z80889 CHEMBL614803 NCI-H322M (Non-small Cell Lung Carcinoma Cells) 2
Z80896 Z80896 CHEMBL614805 NCI-H69 (Small Cell Lung Carcinoma Cells) 2
Z80936 Z80936 CHEMBL614818 HEK293 (Embryonic Kidney Fibroblasts) 2
Z80943 Z80943 CHEMBL614819 HEL 299 2
Z80945 Z80945 CHEMBL614735 HEp-2 (Laryngeal Carcinoma Cells) 2
Z81005 Z81005 CHEMBL614839 HTB-54 Cell Line 2
Z81006 Z81006 CHEMBL612259 Human Breast 401NL Tumor Cell Line 2
Z81017 Z81017 CHEMBL614647 WiDr (Colon Adenocarcinoma Cells) 2
Z81024 Z81024 CHEMBL396 NCI-H460 (Non-small Cell Lung Carcinoma) 2
Z81025 Z81025 CHEMBL613890 Human Lung LXF 529L Tumor Cell Line 2
Z81026 Z81026 CHEMBL614689 Human Lung LXF 629L Tumor Cell Line 2
Z81028 Z81028 CHEMBL613892 Human Melanoma Cell Line 2
Z81034 Z81034 CHEMBL614004 A2780 (Ovarian Carcinoma Cells) 2
Z81043 Z81043 CHEMBL613969 N592 2
Z81054 Z81054 CHEMBL613977 SF-268 (Glioblastoma Cells) 2
Z81072 Z81072 CHEMBL397 Jurkat (Acute Leukemic T-cells) 2
Z81101 Z81101 CHEMBL614010 KBM-3 Cell Line 2
Z81102 Z81102 CHEMBL613994 KBM-3/DOX Cell Line 2
Z81115 Z81115 CHEMBL398 KB (Squamous Cell Carcinoma) 2
Z81133 Z81133 CHEMBL614000 L1210 (1565) 2
Z81134 Z81134 CHEMBL614650 L2987 (Lung Adenocarcinoma Cells) 2
Z81160 Z81160 CHEMBL614088 Lewis Lung Carcinoma Cell Line 2
Z81164 Z81164 CHEMBL614091 LL Cell Line 2
Z81167 Z81167 CHEMBL614093 LLTC Cell Line 2
Z81184 Z81184 CHEMBL614096 LOX IMVI (Melanoma Cells) 2
Z81201 Z81201 CHEMBL614643 HOP-62 (Non-small Cell Lung Carcinoma Cells) 2
Z81211 Z81211 CHEMBL614109 LXFL529 Cell Line 2
Z81244 Z81244 CHEMBL614123 J774 (Macrophage Cells) 2
Z81245 Z81245 CHEMBL614697 MDA-MB-435 (Breast Carcinoma Cells) 2
Z81247 Z81247 CHEMBL399 HeLa (Cervical Adenocarcinoma Cells) 2
Z81257 Z81257 CHEMBL614732 MEL-AC Cell Line 2
Z81261 Z81261 CHEMBL614127 UACC-375 2
Z81277 Z81277 CHEMBL613287 NCI-N417 2
Z81280 Z81280 CHEMBL614740 NCI-H226 (Non-small Cell Lung Carcinoma Cells) 2
Z81284 Z81284 CHEMBL614999 NCI-H647 2
Z81331 Z81331 CHEMBL612262 SW-620 (Colon Adenocarcinoma Cells) 2
Z81335 Z81335 CHEMBL612263 HCT-15 (Colon Adenocarcinoma Cells) 2
Z81341 Z81341 CHEMBL614310 Tumor Cell Lines 2
ANDR_MOUSE P19091 CHEMBL3056 Androgen Receptor, Mouse 1
Z103196 Z103196 CHEMBL1075381 22RV1 1
Z103204 Z103204 CHEMBL1075389 A427 1
Z80427 Z80427 CHEMBL614879 RKO (Colon Carcinoma) 1
Z80453 Z80453 CHEMBL614897 SC-3 1
Z80488 Z80488 CHEMBL614922 SK-MEL-5 (Melanoma Cells) 1
Z80525 Z80525 CHEMBL614055 SW48 1
Z80640 Z80640 CHEMBL613102 786-0 (Renal Carcinoma Cells) 1

Most Common Rings