ZINC 12

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Quick Search ZINC ID or SMILES

Names
Compounds (44)
Reactome (0)
Related By:
Pathway (0)
Organism (-1)
Gene (-1)
Org. Clust. (-1)
ChEMBL (234)
Rings (5)

ZR-75-1 (Breast Carcinoma Cells) (44 Compounds)

Swissprot:: Z80608
Stitch:: Z80608
UniProt:: Z80608
ChEMBL:: CHEMBL614393

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Functional ≤ 10μM	44	20	11	10
ADME/T ≤ 10μM	7	2	2	1

Clustered By Gene (0)

Uniprot	Swissprot	Chembl	Description	Number Shared
Z80712	Z80712	CHEMBL614361	T47D (Breast Carcinoma Cells)	35
Z80224	Z80224	CHEMBL387	MCF7 (Breast Carcinoma Cells)	22
Z81252	Z81252	CHEMBL400	MDA-MB-231 (Breast Adenocarcinoma Cells)	21
Z80244	Z80244	CHEMBL614335	MDA-MB-468 (Breast Adenocarcinoma)	17
Z80475	Z80475	CHEMBL613834	SK-BR-3 (Breast Adenocarcinoma)	17
Z80682	Z80682	CHEMBL392	A549 (Lung Carcinoma Cells)	17
Z81024	Z81024	CHEMBL396	NCI-H460 (Non-small Cell Lung Carcinoma)	14
Z80928	Z80928	CHEMBL394	HCT-116 (Colon Carcinoma Cells)	13
Z81247	Z81247	CHEMBL399	HeLa (Cervical Adenocarcinoma Cells)	13
Z81284	Z81284	CHEMBL614999	NCI-H647	13
Z80322	Z80322	CHEMBL614135	NCI-H358 (Lung Carcinama Cells)	12
Z81280	Z81280	CHEMBL614740	NCI-H226 (Non-small Cell Lung Carcinoma Cells)	12
Z80120	Z80120	CHEMBL614285	DLD-1 (Colon Adenocarcinoma Cells)	11
Z80846	Z80846	CHEMBL614493	F460pv8/eto Cell Line	11
Z80889	Z80889	CHEMBL614803	NCI-H322M (Non-small Cell Lung Carcinoma Cells)	11
Z80156	Z80156	CHEMBL383	HL-60 (Promyeloblast Leukemia Cells)	9
Z80227	Z80227	CHEMBL614324	MCF7-ADR (Breast Carcinoma Cells)	9
Z80390	Z80390	CHEMBL390	PC-3 (Prostate Carcinoma Cells)	9
Z80166	Z80166	CHEMBL384	HT-29 (Colon Adenocarcinoma Cells)	8
Z80193	Z80193	CHEMBL386	L1210 (Lymphocytic Leukemia Cells)	8
Z103205	Z103205	CHEMBL1075390	A431	7
Z80025	Z80025	CHEMBL614519	ACHN (Renal Adenocarcinoma Cells)	7
Z80125	Z80125	CHEMBL613508	DU-145 (Prostate Carcinoma)	7
Z80164	Z80164	CHEMBL614580	HT-1080 (Fibrosarcoma Cells)	7
Z80211	Z80211	CHEMBL614721	LoVo (Colon Adenocarcinoma Cells)	7
Z81335	Z81335	CHEMBL612263	HCT-15 (Colon Adenocarcinoma Cells)	7
Z80354	Z80354	CHEMBL614213	OVCAR-3 (Ovarian Adenocarcinoma Cells)	6
Z80485	Z80485	CHEMBL614919	SK-MEL-28 (Melanoma Cells)	6
Z81072	Z81072	CHEMBL397	Jurkat (Acute Leukemic T-cells)	6
Z81170	Z81170	CHEMBL612518	LNCaP (Prostate Carcinoma)	6
Z50425	Z50425	CHEMBL364	Plasmodium Falciparum	5
Z80021	Z80021	CHEMBL614516	A498 (Renal Carcinoma Cells)	5
Z80186	Z80186	CHEMBL385	K562 (Erythroleukemia Cells)	5
Z80254	Z80254	CHEMBL614343	MES-SA (Uterine Sarcoma Cells)	5
Z80362	Z80362	CHEMBL389	P388 (Lymphoma Cells)	5
Z80493	Z80493	CHEMBL614925	SK-OV-3 (Ovarian Carcinoma Cells)	5
Z80532	Z80532	CHEMBL614774	T-24 (Bladder Carcinoma Cells)	5
Z80563	Z80563	CHEMBL615025	U-373 MG ( Glioblastoma Cells)	5
Z80565	Z80565	CHEMBL614247	U-87 MG (Glioblastoma Cells)	5
Z80661	Z80661	CHEMBL614567	A704 (Renal Carcinoma Cells)	5
Z80819	Z80819	CHEMBL614484	J774.2	5
Z81017	Z81017	CHEMBL614647	WiDr (Colon Adenocarcinoma Cells)	5
Z81244	Z81244	CHEMBL614123	J774 (Macrophage Cells)	5
TOP1_HUMAN	P11387	CHEMBL1781	DNA Topoisomerase I, Human	4
TOP1_MOUSE	Q04750	CHEMBL2814	DNA Topoisomerase I, Mouse	4
TOP2A_HUMAN	P11388	CHEMBL1806	DNA Topoisomerase II Alpha, Human	4
TOP2A_MOUSE	Q01320	CHEMBL3586	DNA Topoisomerase II Alpha, Mouse	4
TOP2B_HUMAN	Q02880	CHEMBL3396	DNA Topoisomerase II Beta, Human	4
TOP2B_MOUSE	Q64511	CHEMBL5564	DNA Topoisomerase II Beta, Mouse	4
Z103203	Z103203	CHEMBL1075388	A375	4
Z50587	Z50587	CHEMBL372	Homo Sapiens	4
Z80035	Z80035	CHEMBL381	B16 (Melanoma Cells)	4
Z80064	Z80064	CHEMBL382	CCRF-CEM (T-cell Leukemia)	4
Z80088	Z80088	CHEMBL613853	CHO (Ovarian Cells)	4
Z80269	Z80269	CHEMBL614354	MKN-45 (Gastric Adenocarcinoma Cells)	4
Z80640	Z80640	CHEMBL613102	786-0 (Renal Carcinoma Cells)	4
Z80852	Z80852	CHEMBL614069	A-431 (Epidermoid Carcinoma Cells)	4
Z80874	Z80874	CHEMBL393	CEM (T-cell Leukemia)	4
Z80991	Z80991	CHEMBL614645	Hs-578T (Breast Carcinoma Cells)	4
Z81020	Z81020	CHEMBL395	HepG2 (Hepatoblastoma Cells)	4
Z81054	Z81054	CHEMBL613977	SF-268 (Glioblastoma Cells)	4
Z81115	Z81115	CHEMBL398	KB (Squamous Cell Carcinoma)	4
Z81160	Z81160	CHEMBL614088	Lewis Lung Carcinoma Cell Line	4
Z80008	Z80008	CHEMBL612565	5637 (Epithelial Bladder Carcinoma Cells)	3
Z80014	Z80014	CHEMBL614514	A204 (Rhabdomyosarcoma Cells)	3
Z80019	Z80019	CHEMBL614515	A-427 (Lung Carcinoma Cells)	3
Z80026	Z80026	CHEMBL613860	AGS (Gastric Adenocarcinoma Cells)	3
Z80045	Z80045	CHEMBL613870	BT-20 (Breast Carcinoma Cells)	3
Z80048	Z80048	CHEMBL614530	BXPC-3 (Pancreatic Adenocarcinoma Cells)	3
Z80056	Z80056	CHEMBL613852	CAKI-2 (Renal Carcinoma Cells)	3
Z80068	Z80068	CHEMBL614542	CCRF-SB (Lymphoblastic Leukemia Cells)	3
Z80086	Z80086	CHEMBL613506	CFPAC-1 (Pancreatic Carcinoma Cells)	3
Z80188	Z80188	CHEMBL614590	KB 3-1 (Cervical Epithelial Carcinoma Cells)	3
Z80285	Z80285	CHEMBL614177	MOLT-4 (Acute T-lymphoblastic Leukemia Cells)	3
Z80295	Z80295	CHEMBL388	MT4 (Lymphocytes)	3
Z80381	Z80381	CHEMBL614139	PANC-1 (Pancreatic Carcinoma Cells)	3
Z80414	Z80414	CHEMBL614628	Raji (B-lymphoblastic Cells)	3
Z80466	Z80466	CHEMBL614907	SF268	3
Z80482	Z80482	CHEMBL614917	SK-MEL-2 (Melanoma Cells)	3
Z80490	Z80490	CHEMBL614923	SK-MES-1	3
Z80491	Z80491	CHEMBL614163	SK-N-MC (Neuroepithelioma Cells)	3
Z80526	Z80526	CHEMBL612544	SW480 (Colon Adenocarcinoma Cells)	3
Z80539	Z80539	CHEMBL614775	T98G (Glioblastoma Cells)	3
Z80559	Z80559	CHEMBL615021	U251	3
Z80583	Z80583	CHEMBL391	Vero (Kidney Cells)	3
Z80600	Z80600	CHEMBL613533	XF498 (Glioma Cells)	3
Z80697	Z80697	CHEMBL614279	Bel-7402 (Hepatoma Cells)	3
Z80800	Z80800	CHEMBL614725	MIA PaCa-2 (Pancreatic Carcinoma Cells)	3
Z80847	Z80847	CHEMBL612250	FaDu (Pharyngeal Carcinoma Cells)	3
Z80891	Z80891	CHEMBL614804	H4 (Hepatoma Cells)	3
Z80896	Z80896	CHEMBL614805	NCI-H69 (Small Cell Lung Carcinoma Cells)	3
Z80996	Z80996	CHEMBL614836	HT1197 (Bladder Carcinoma Cells)	3
Z81034	Z81034	CHEMBL614004	A2780 (Ovarian Carcinoma Cells)	3
Z81043	Z81043	CHEMBL613969	N592	3
Z81164	Z81164	CHEMBL614091	LL Cell Line	3
Z81167	Z81167	CHEMBL614093	LLTC Cell Line	3
Z81245	Z81245	CHEMBL614697	MDA-MB-435 (Breast Carcinoma Cells)	3
Z81248	Z81248	CHEMBL614021	Malme-3M (Melanoma Cells)	3
Z81331	Z81331	CHEMBL612262	SW-620 (Colon Adenocarcinoma Cells)	3
ESR1_HUMAN	P03372	CHEMBL206	Estrogen Receptor Alpha, Human	2
ESR2_HUMAN	Q92731	CHEMBL242	Estrogen Receptor Beta, Human	2
Z100733	Z100733	CHEMBL613866	CT26 (Colon Carcinoma Cells)	2
Z103219	Z103219	CHEMBL1075404	Ca9-22	2
Z50347	Z50347	CHEMBL361	Saccharomyces Cerevisiae	2
Z50643	Z50643	CHEMBL379	Hepatitis C Virus	2
Z80017	Z80017	CHEMBL614023	A2780cisR (Cisplatin-resistant Ovarian Carcinoma Cells)	2
Z80018	Z80018	CHEMBL613859	A-375 (Malignant Melanoma Cells)	2
Z80039	Z80039	CHEMBL614526	BGC-823 (Stomach Adenocarcinoma Cells)	2
Z80052	Z80052	CHEMBL614533	C8166 (Leukemic T-cells)	2
Z80054	Z80054	CHEMBL614058	Caco-2 (Colon Adenocarcinoma Cells)	2
Z80092	Z80092	CHEMBL614031	CHO-K1 (Ovarian Cells)	2
Z80105	Z80105	CHEMBL613854	COR-L23 (Lung Carcinoma Cells)	2
Z80114	Z80114	CHEMBL614281	Daudi (Burkitts Lymphoma Cells)	2
Z80126	Z80126	CHEMBL614289	DuPro	2
Z80138	Z80138	CHEMBL614036	G-361 (Melanoma Cells)	2
Z80145	Z80145	CHEMBL614045	H69	2
Z80175	Z80175	CHEMBL614585	IMR-32 (Neuroblastoma Cells)	2
Z80214	Z80214	CHEMBL614317	M14 (Melanoma Cells)	2
Z80240	Z80240	CHEMBL614129	MDA-MB-361	2
Z80243	Z80243	CHEMBL614334	MDA-MB-453 (Breast Adenocarcinoma Cells)	2
Z80255	Z80255	CHEMBL613827	MES-SA/DxS (Uterine Sarcoma Cells)	2
Z80267	Z80267	CHEMBL614352	MKN-1	2
Z80291	Z80291	CHEMBL614181	MRC5 (Embryonic Lung Fibroblast Cells)	2
Z80330	Z80330	CHEMBL614197	NCI-N87	2
Z80364	Z80364	CHEMBL614218	P388/ADR (Lymphoma Cells)	2
Z80367	Z80367	CHEMBL614220	P388/S	2
Z80389	Z80389	CHEMBL614140	PC-14	2
Z80433	Z80433	CHEMBL614882	RPMI-8226 (Multiple Myeloma Cells)	2
Z80441	Z80441	CHEMBL614889	RXF 944	2
Z80468	Z80468	CHEMBL614908	SF-295 (Glioblastoma Cells)	2
Z80472	Z80472	CHEMBL612542	SiHa (Cervical Squamous Cell Carcinoma)	2
Z80477	Z80477	CHEMBL614912	SK_HEP1 (Hepatoma Cells)	2
Z80479	Z80479	CHEMBL614914	SK-MEL (Melanoma Cells)	2
Z80481	Z80481	CHEMBL614916	SK-MEL-1 (Metastatic Melanoma Cells)	2
Z80492	Z80492	CHEMBL614924	SK-N-SH (Neuroblastoma Cells)	2
Z80495	Z80495	CHEMBL614927	SK-VLB	2
Z80503	Z80503	CHEMBL614931	SNU1	2
Z80509	Z80509	CHEMBL614935	SNU-638 (Gastric Carcinoma Cells)	2
Z80560	Z80560	CHEMBL615022	U-251 (Glioma Cells)	2
Z80574	Z80574	CHEMBL612799	UMUC3	2
Z80581	Z80581	CHEMBL614248	VA13	2
Z80595	Z80595	CHEMBL612810	WIL2-NS (Lymphoblastoid Cells)	2
Z80601	Z80601	CHEMBL614060	XRS6	2
Z80726	Z80726	CHEMBL614367	TRAMP-C1A (Prostate Carcinoma Cells)	2
Z80730	Z80730	CHEMBL614368	C2D Cell Line	2
Z80731	Z80731	CHEMBL613541	C2G Cell Line	2
Z80732	Z80732	CHEMBL614369	TRAMP-C2H (Prostate Carcinoma Cells)	2
Z80735	Z80735	CHEMBL614739	C38 (Colon Carcinoma)	2
Z80768	Z80768	CHEMBL614455	CH1 (Ovarian Carcinoma Cells)	2
Z80784	Z80784	CHEMBL614462	Col2 (Colon Carcinoma Cells)	2
Z80801	Z80801	CHEMBL614151	CRL-7065 Cell Line	2
Z80887	Z80887	CHEMBL614802	H2981 Cell Line	2
Z80936	Z80936	CHEMBL614818	HEK293 (Embryonic Kidney Fibroblasts)	2
Z80943	Z80943	CHEMBL614819	HEL 299	2
Z80945	Z80945	CHEMBL614735	HEp-2 (Laryngeal Carcinoma Cells)	2
Z81005	Z81005	CHEMBL614839	HTB-54 Cell Line	2
Z81006	Z81006	CHEMBL612259	Human Breast 401NL Tumor Cell Line	2
Z81025	Z81025	CHEMBL613890	Human Lung LXF 529L Tumor Cell Line	2
Z81026	Z81026	CHEMBL614689	Human Lung LXF 629L Tumor Cell Line	2
Z81028	Z81028	CHEMBL613892	Human Melanoma Cell Line	2
Z81101	Z81101	CHEMBL614010	KBM-3 Cell Line	2
Z81102	Z81102	CHEMBL613994	KBM-3/DOX Cell Line	2
Z81133	Z81133	CHEMBL614000	L1210 (1565)	2
Z81134	Z81134	CHEMBL614650	L2987 (Lung Adenocarcinoma Cells)	2
Z81184	Z81184	CHEMBL614096	LOX IMVI (Melanoma Cells)	2
Z81201	Z81201	CHEMBL614643	HOP-62 (Non-small Cell Lung Carcinoma Cells)	2
Z81211	Z81211	CHEMBL614109	LXFL529 Cell Line	2
Z81257	Z81257	CHEMBL614732	MEL-AC Cell Line	2
Z81261	Z81261	CHEMBL614127	UACC-375	2
Z81277	Z81277	CHEMBL613287	NCI-N417	2
Z81341	Z81341	CHEMBL614310	Tumor Cell Lines	2
EGFR_HUMAN	P00533	CHEMBL203	Epidermal Growth Factor Receptor ErbB1, Human	1
IGF1R_HUMAN	P08069	CHEMBL1957	Insulin-like Growth Factor I Receptor, Human	1
MPRI_HUMAN	P11717	CHEMBL3240	Insulin-like Growth Factor II Receptor, Human	1
Q862F3_BOVIN	Q862F3	CHEMBL4262	Tubulin Alpha Chain, Bovin	1
Q862L2_BOVIN	Q862L2	CHEMBL3752	Tubulin Alpha-1 Chain, Bovin	1
TBA1A_PIG	P02550	CHEMBL3658	Tubulin Alpha Chain, Pig	1
TBA1A_RAT	P68370	CHEMBL4139	Tubulin Alpha-1 Chain, Rat	1
TBA4A_HUMAN	P68366	CHEMBL2070	Tubulin Alpha-1 Chain, Human	1
TBB1_HUMAN	Q9H4B7	CHEMBL1915	Tubulin Beta-1 Chain, Human	1
TBB2B_BOVIN	Q6B856	CHEMBL3394	Tubulin Beta Chain, Bovin	1
TBB3_HUMAN	Q13509	CHEMBL2597	Tubulin Beta-3 Chain, Human	1
TBB4A_HUMAN	P04350	CHEMBL3838	Tubulin Beta-4 Chain, Human	1
TBB4B_HUMAN	P68371	CHEMBL1848	Tubulin Beta-2 Chain, Human	1
TBB5_HUMAN	P07437	CHEMBL5444	Tubulin Beta-5 Chain, Human	1
TBB8_HUMAN	Q3ZCM7	CHEMBL4024	Tubulin Beta-8 Chain, Human	1
Z100495	Z100495	CHEMBL613880	BMEC (Brain Microvessel Endothelial Cells)	1
Z100752	Z100752	CHEMBL612568	Renca (Renal Carcinoma Cells)	1
Z101682	Z101682	CHEMBL613915	BK Polyomavirus	1
Z103196	Z103196	CHEMBL1075381	22RV1	1
Z103204	Z103204	CHEMBL1075389	A427	1
Z103413	Z103413	CHEMBL1075598	SW948	1
Z50460	Z50460	CHEMBL612879	Leishmania Major	1
Z50590	Z50590	CHEMBL613488	Sus Scrofa	1
Z50607	Z50607	CHEMBL378	Human Immunodeficiency Virus 1	1
Z80002	Z80002	CHEMBL614075	1A9 (Ovarian Adenocarcinoma Cells)	1
Z80013	Z80013	CHEMBL614513	A10	1
Z80024	Z80024	CHEMBL614518	A9 (Fibroblast Cells)	1
Z80084	Z80084	CHEMBL614554	CEM-VLB (Vinblastine-resistant T-cell Leukemia Cells)	1
Z80085	Z80085	CHEMBL614030	CEM-VM1 (Etoposide-resistant T-cell Leukemia Cells)	1
Z80089	Z80089	CHEMBL614555	CHO-AA8	1
Z80096	Z80096	CHEMBL614559	CHO-TAX 5-6	1
Z80097	Z80097	CHEMBL614560	CHO-VV 3-2	1
Z80112	Z80112	CHEMBL614033	DAN-G	1
Z80115	Z80115	CHEMBL612702	DC3F	1
Z80117	Z80117	CHEMBL614283	DC3F/AD-II	1
Z80152	Z80152	CHEMBL613510	HCT-8 (Ileocecal Adenocarcinoma)	1
Z80179	Z80179	CHEMBL614586	J82 (Bladder Carcinoma Cells)	1
Z80284	Z80284	CHEMBL614176	MOLT-3 (T-lymphoblastic Leukemia Cells)	1
Z80288	Z80288	CHEMBL614133	MOVP-3	1
Z80310	Z80310	CHEMBL614191	NCH82	1
Z80316	Z80316	CHEMBL614771	NCI-H128	1
Z80427	Z80427	CHEMBL614879	RKO (Colon Carcinoma)	1
Z80435	Z80435	CHEMBL614145	RT-112	1
Z80436	Z80436	CHEMBL614884	RT-4	1
Z80473	Z80473	CHEMBL613527	SISO	1
Z80546	Z80546	CHEMBL615013	TERT-RPE1 (Retinal Pigmented Epithelial Cells)	1
Z80548	Z80548	CHEMBL614245	THP-1 (Acute Monocytic Leukemia Cells)	1
Z80566	Z80566	CHEMBL612794	U-937 (Histiocytic Lymphoma Cells)	1
Z80604	Z80604	CHEMBL612815	YAPC	1
Z80612	Z80612	CHEMBL612818	2008 (Ovarian Carcinoma Cells)	1
Z80711	Z80711	CHEMBL613829	NCI/ADR-RES (Breast Carcinoma Cells)	1
Z80720	Z80720	CHEMBL614365	Burkitts Lymphoma Cells	1
Z80866	Z80866	CHEMBL612707	GLC4 Cell Line	1
Z80878	Z80878	CHEMBL614783	NCI-H157 (Non-small Cell Lung Carcinoma Cells)	1
Z80897	Z80897	CHEMBL614806	H9 (T-lymphoid Cells)	1
Z80901	Z80901	CHEMBL614392	HaCaT (Keratinocytes)	1
Z81057	Z81057	CHEMBL613979	HUVEC (Umbilical Vein Endothelial Cells)	1
Z81065	Z81065	CHEMBL613984	IGROV-1 (Ovarian Adenocarcinoma Cells)	1
Z81126	Z81126	CHEMBL613998	KYSE-150 Cell Line	1
Z81128	Z81128	CHEMBL612701	KYSE-520 Cell Line	1
Z81130	Z81130	CHEMBL614012	KYSE-70 Cell Line	1
Z81281	Z81281	CHEMBL614997	NCI-H23 (Non-small Cell Lung Carcinoma Cells)	1
Z81283	Z81283	CHEMBL614387	NCI-H522 (Non-small Cell Lung Carcinoma Cells)	1