UCSF

Somatostatin Receptor 2, Human (305 Compounds)

Swissprot:
SSR2_HUMAN
Stitch:
SSR2_HUMAN
UniProt:
P30874
ChEMBL:
CHEMBL1804
Reactome:
REACT_19231
REACT_14819
PDB:
SSTR2

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 305 0 0 0
Binding ≤ 1μM 248 0 0 0
Functional ≤ 10μM 31 1 1 1

Reactome Network (2)

Reactome ID Description Species
REACT_19231 G alpha (i) signalling events Homo sapiens
REACT_14819 Peptide ligand-binding receptors Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
SSR1_HUMAN P30872 CHEMBL1917 Somatostatin Receptor 1, Human 74
SSR3_HUMAN P32745 CHEMBL2028 Somatostatin Receptor 3, Human 81
SSR4_HUMAN P31391 CHEMBL1853 Somatostatin Receptor 4, Human 97
SSR5_HUMAN P35346 CHEMBL1792 Somatostatin Receptor 5, Human 94

Peptide ligand-binding receptors

Uniprot Swissprot Chembl Description Number Shared
SSR1_HUMAN P30872 CHEMBL1917 Somatostatin Receptor 1, Human 74
SSR3_HUMAN P32745 CHEMBL2028 Somatostatin Receptor 3, Human 81
SSR4_HUMAN P31391 CHEMBL1853 Somatostatin Receptor 4, Human 97
SSR5_HUMAN P35346 CHEMBL1792 Somatostatin Receptor 5, Human 94
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
SSR2_MOUSE P30875 CHEMBL3207 Somatostatin Receptor 2, Mouse 11 0 0 0
SSR2_RAT P30680 CHEMBL2978 Somatostatin Receptor 2, Rat 4 0 0 0
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
SSR1_HUMAN P30872 CHEMBL1917 Somatostatin Receptor 1, Human 93 0 0 0
SSR3_HUMAN P32745 CHEMBL2028 Somatostatin Receptor 3, Human 143 0 0 0
SSR4_HUMAN P31391 CHEMBL1853 Somatostatin Receptor 4, Human 116 1 0 0
SSR5_HUMAN P35346 CHEMBL1792 Somatostatin Receptor 5, Human 219 1 1 1

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
SSR4_HUMAN P31391 CHEMBL1853 Somatostatin Receptor 4, Human 97
SSR5_HUMAN P35346 CHEMBL1792 Somatostatin Receptor 5, Human 94
SSR3_HUMAN P32745 CHEMBL2028 Somatostatin Receptor 3, Human 81
SSR1_HUMAN P30872 CHEMBL1917 Somatostatin Receptor 1, Human 74
SSR1_MOUSE P30873 CHEMBL4242 Somatostatin Receptor 1, Mouse 5
SSR2_MOUSE P30875 CHEMBL3207 Somatostatin Receptor 2, Mouse 5
SSR3_MOUSE P30935 CHEMBL2238 Somatostatin Receptor 3, Mouse 5
SSR4_MOUSE P49660 CHEMBL4397 Somatostatin Receptor 4, Mouse 5
SSR5_MOUSE O08858 CHEMBL2733 Somatostatin Receptor 5, Mouse 5
Z81011 Z81011 CHEMBL614840 Human Cell Lines 3
ADRB2_HUMAN P07550 CHEMBL210 Beta-2 Adrenergic Receptor, Human 2
NK1R_HUMAN P25103 CHEMBL249 Neurokinin 1 Receptor, Human 2
CHK1_HUMAN O14757 CHEMBL4630 Serine/threonine-protein Kinase Chk1, Human 1
SSR1_RAT P28646 CHEMBL4652 Somatostatin Receptor 1, Rat 1
SSR2_RAT P30680 CHEMBL2978 Somatostatin Receptor 2, Rat 1
SSR4_RAT P30937 CHEMBL4560 Somatostatin Receptor 4, Rat 1
SSR5_RAT P30938 CHEMBL4318 Somatostatin Receptor 5, Rat 1
TOP1_HUMAN P11387 CHEMBL1781 DNA Topoisomerase I, Human 1
TOP1_MOUSE Q04750 CHEMBL2814 DNA Topoisomerase I, Mouse 1
TOP2A_HUMAN P11388 CHEMBL1806 DNA Topoisomerase II Alpha, Human 1
TOP2A_MOUSE Q01320 CHEMBL3586 DNA Topoisomerase II Alpha, Mouse 1
TOP2B_HUMAN Q02880 CHEMBL3396 DNA Topoisomerase II Beta, Human 1
TOP2B_MOUSE Q64511 CHEMBL5564 DNA Topoisomerase II Beta, Mouse 1
Z100501 Z100501 CHEMBL613290 Lu1 (Lung Carcinoma Cells) 1
Z100733 Z100733 CHEMBL613866 CT26 (Colon Carcinoma Cells) 1
Z100752 Z100752 CHEMBL612568 Renca (Renal Carcinoma Cells) 1
Z103205 Z103205 CHEMBL1075390 A431 1
Z103408 Z103408 CHEMBL1075593 SW626 1
Z103413 Z103413 CHEMBL1075598 SW948 1
Z50425 Z50425 CHEMBL364 Plasmodium Falciparum 1
Z80012 Z80012 CHEMBL614512 A 172 (Glioblastoma Cells) 1
Z80019 Z80019 CHEMBL614515 A-427 (Lung Carcinoma Cells) 1
Z80026 Z80026 CHEMBL613860 AGS (Gastric Adenocarcinoma Cells) 1
Z80054 Z80054 CHEMBL614058 Caco-2 (Colon Adenocarcinoma Cells) 1
Z80056 Z80056 CHEMBL613852 CAKI-2 (Renal Carcinoma Cells) 1
Z80064 Z80064 CHEMBL382 CCRF-CEM (T-cell Leukemia) 1
Z80068 Z80068 CHEMBL614542 CCRF-SB (Lymphoblastic Leukemia Cells) 1
Z80099 Z80099 CHEMBL614561 COLO 205 (Colon Adenocarcinoma Cells) 1
Z80115 Z80115 CHEMBL612702 DC3F 1
Z80120 Z80120 CHEMBL614285 DLD-1 (Colon Adenocarcinoma Cells) 1
Z80125 Z80125 CHEMBL613508 DU-145 (Prostate Carcinoma) 1
Z80145 Z80145 CHEMBL614045 H69 1
Z80152 Z80152 CHEMBL613510 HCT-8 (Ileocecal Adenocarcinoma) 1
Z80156 Z80156 CHEMBL383 HL-60 (Promyeloblast Leukemia Cells) 1
Z80164 Z80164 CHEMBL614580 HT-1080 (Fibrosarcoma Cells) 1
Z80166 Z80166 CHEMBL384 HT-29 (Colon Adenocarcinoma Cells) 1
Z80186 Z80186 CHEMBL385 K562 (Erythroleukemia Cells) 1
Z80188 Z80188 CHEMBL614590 KB 3-1 (Cervical Epithelial Carcinoma Cells) 1
Z80193 Z80193 CHEMBL386 L1210 (Lymphocytic Leukemia Cells) 1
Z80211 Z80211 CHEMBL614721 LoVo (Colon Adenocarcinoma Cells) 1
Z80224 Z80224 CHEMBL387 MCF7 (Breast Carcinoma Cells) 1
Z80269 Z80269 CHEMBL614354 MKN-45 (Gastric Adenocarcinoma Cells) 1
Z80295 Z80295 CHEMBL388 MT4 (Lymphocytes) 1
Z80316 Z80316 CHEMBL614771 NCI-H128 1
Z80362 Z80362 CHEMBL389 P388 (Lymphoma Cells) 1
Z80372 Z80372 CHEMBL614224 P388CPT5 1
Z80390 Z80390 CHEMBL390 PC-3 (Prostate Carcinoma Cells) 1
Z80414 Z80414 CHEMBL614628 Raji (B-lymphoblastic Cells) 1
Z80466 Z80466 CHEMBL614907 SF268 1
Z80475 Z80475 CHEMBL613834 SK-BR-3 (Breast Adenocarcinoma) 1
Z80482 Z80482 CHEMBL614917 SK-MEL-2 (Melanoma Cells) 1
Z80485 Z80485 CHEMBL614919 SK-MEL-28 (Melanoma Cells) 1
Z80493 Z80493 CHEMBL614925 SK-OV-3 (Ovarian Carcinoma Cells) 1
Z80495 Z80495 CHEMBL614927 SK-VLB 1
Z80532 Z80532 CHEMBL614774 T-24 (Bladder Carcinoma Cells) 1
Z80548 Z80548 CHEMBL614245 THP-1 (Acute Monocytic Leukemia Cells) 1
Z80623 Z80623 CHEMBL612911 Panel (56 Tumour Cell Lines) 1
Z80647 Z80647 CHEMBL613103 833K Cell Line 1
Z80682 Z80682 CHEMBL392 A549 (Lung Carcinoma Cells) 1
Z80697 Z80697 CHEMBL614279 Bel-7402 (Hepatoma Cells) 1
Z80712 Z80712 CHEMBL614361 T47D (Breast Carcinoma Cells) 1
Z80751 Z80751 CHEMBL614379 Caov-3 Cell Line 1
Z80784 Z80784 CHEMBL614462 Col2 (Colon Carcinoma Cells) 1
Z80799 Z80799 CHEMBL612517 RPMI 8402 (Pre-T-lymphoblastoid Cells) 1
Z80874 Z80874 CHEMBL393 CEM (T-cell Leukemia) 1
Z80898 Z80898 CHEMBL614785 NCI-H928 1
Z80928 Z80928 CHEMBL394 HCT-116 (Colon Carcinoma Cells) 1
Z80930 Z80930 CHEMBL614817 HEC-1B Cell Line 1
Z81017 Z81017 CHEMBL614647 WiDr (Colon Adenocarcinoma Cells) 1
Z81020 Z81020 CHEMBL395 HepG2 (Hepatoblastoma Cells) 1
Z81024 Z81024 CHEMBL396 NCI-H460 (Non-small Cell Lung Carcinoma) 1
Z81034 Z81034 CHEMBL614004 A2780 (Ovarian Carcinoma Cells) 1
Z81054 Z81054 CHEMBL613977 SF-268 (Glioblastoma Cells) 1
Z81072 Z81072 CHEMBL397 Jurkat (Acute Leukemic T-cells) 1
Z81080 Z81080 CHEMBL613991 KATO-III Cell Line 1
Z81084 Z81084 CHEMBL613992 KB VCR R 1
Z81115 Z81115 CHEMBL398 KB (Squamous Cell Carcinoma) 1
Z81134 Z81134 CHEMBL614650 L2987 (Lung Adenocarcinoma Cells) 1
Z81160 Z81160 CHEMBL614088 Lewis Lung Carcinoma Cell Line 1
Z81164 Z81164 CHEMBL614091 LL Cell Line 1
Z81170 Z81170 CHEMBL612518 LNCaP (Prostate Carcinoma) 1
Z81184 Z81184 CHEMBL614096 LOX IMVI (Melanoma Cells) 1
Z81245 Z81245 CHEMBL614697 MDA-MB-435 (Breast Carcinoma Cells) 1
Z81247 Z81247 CHEMBL399 HeLa (Cervical Adenocarcinoma Cells) 1
Z81252 Z81252 CHEMBL400 MDA-MB-231 (Breast Adenocarcinoma Cells) 1
Z81331 Z81331 CHEMBL612262 SW-620 (Colon Adenocarcinoma Cells) 1
Z81335 Z81335 CHEMBL612263 HCT-15 (Colon Adenocarcinoma Cells) 1