UCSF

Platelet-derived Growth Factor Receptor Beta, Rat (18 Compounds)

Swissprot:
PGFRB_RAT
Stitch:
PGFRB_RAT
UniProt:
Q05030
ChEMBL:
CHEMBL4125
Reactome:
REACT_198729
REACT_206819
REACT_257653
REACT_212371
PDB:
Pdgfrb

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 18 5 0 0
Binding ≤ 1μM 12 3 0 0
Functional ≤ 10μM 53 11 1 1
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
PGFRB_HUMAN P09619 CHEMBL1913 Platelet-derived Growth Factor Receptor Beta, Human 796 66 25 38
PGFRB_MOUSE P05622 CHEMBL2749 Platelet-derived Growth Factor Receptor Beta, Mouse 323 44 2 3

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
PGFRA_RAT P20786 CHEMBL2513 Platelet-derived Growth Factor Receptor Alpha, Rat 45
FGFR1_HUMAN P11362 CHEMBL3650 Fibroblast Growth Factor Receptor 1, Human 28
FGFR2_HUMAN P21802 CHEMBL4142 Fibroblast Growth Factor Receptor 2, Human 26
FGFR3_HUMAN P22607 CHEMBL2742 Fibroblast Growth Factor Receptor 3, Human 26
FGFR4_HUMAN P22455 CHEMBL3973 Fibroblast Growth Factor Receptor 4, Human 26
Z80742 Z80742 CHEMBL614657 C6 (Glioma Cells) 26
PGFRB_MOUSE P05622 CHEMBL2749 Platelet-derived Growth Factor Receptor Beta, Mouse 21
Z81057 Z81057 CHEMBL613979 HUVEC (Umbilical Vein Endothelial Cells) 17
VGFR1_HUMAN P17948 CHEMBL1868 Vascular Endothelial Growth Factor Receptor 1, Human 14
VGFR2_HUMAN P35968 CHEMBL279 Vascular Endothelial Growth Factor Receptor 2, Human 14
VGFR3_HUMAN P35916 CHEMBL1955 Vascular Endothelial Growth Factor Receptor 3, Human 14
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 12
SRC_HUMAN P12931 CHEMBL267 Tyrosine-protein Kinase SRC, Human 10
PGFRA_MOUSE P26618 CHEMBL3466 Platelet-derived Growth Factor Receptor Alpha, Mouse 9
SRC_CHICK P00523 CHEMBL3655 Tyrosine-protein Kinase SRC, Chick 8
Z80951 Z80951 CHEMBL614822 NIH3T3 (Fibroblasts) 7
FGFR1_MOUSE P16092 CHEMBL3960 Fibroblast Growth Factor Receptor 1, Mouse 6
Z80166 Z80166 CHEMBL384 HT-29 (Colon Adenocarcinoma Cells) 6
FGFR2_MOUSE P21803 CHEMBL3648 Fibroblast Growth Factor Receptor 2, Mouse 5
FGFR3_MOUSE Q61851 CHEMBL4066 Fibroblast Growth Factor Receptor 3, Mouse 5
FGFR4_MOUSE Q03142 CHEMBL3839 Fibroblast Growth Factor Receptor 4, Mouse 5
SRC_MOUSE P05480 CHEMBL3074 Tyrosine-protein Kinase SRC, Mouse 5
MK01_HUMAN P28482 CHEMBL4040 MAP Kinase ERK2, Human 3
MP2K1_HUMAN Q02750 CHEMBL3587 Dual Specificity Mitogen-activated Protein Kinase Kinase 1, Human 3
Z80152 Z80152 CHEMBL613510 HCT-8 (Ileocecal Adenocarcinoma) 3
Z81331 Z81331 CHEMBL612262 SW-620 (Colon Adenocarcinoma Cells) 3
PGFRA_HUMAN P16234 CHEMBL2007 Platelet-derived Growth Factor Receptor Alpha, Human 2
PGFRB_HUMAN P09619 CHEMBL1913 Platelet-derived Growth Factor Receptor Beta, Human 2
ABL1_HUMAN P00519 CHEMBL1862 Tyrosine-protein Kinase ABL, Human 1
ABL2_HUMAN P42684 CHEMBL4014 Tyrosine-protein Kinase ABL2, Human 1
CSK_MOUSE P41241 CHEMBL2333 Tyrosine-protein Kinase CSK, Mouse 1
ERBB2_HUMAN P04626 CHEMBL1824 Receptor Protein-tyrosine Kinase ErbB-2, Human 1
FYN_HUMAN P06241 CHEMBL1841 Tyrosine-protein Kinase FYN, Human 1
WEE1_HUMAN P30291 CHEMBL5491 Serine/threonine-protein Kinase WEE1, Human 1
Z104300 Z104300 CHEMBL1907606 Mitogen-activated Protein Kinase; ERK1/ERK2 1
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 1
Z80036 Z80036 CHEMBL614524 BaF3 (IL-3-dependent Pro-B-cells) 1
Z80186 Z80186 CHEMBL385 K562 (Erythroleukemia Cells) 1
Z80416 Z80416 CHEMBL614630 Rat1 (Fibroblast Cells) 1
Z81020 Z81020 CHEMBL395 HepG2 (Hepatoblastoma Cells) 1
Z81037 Z81037 CHEMBL613967 Human Ovarian Carcinoma Cell Line 1
Z81125 Z81125 CHEMBL613997 KU812 Cell Line 1
Z81328 Z81328 CHEMBL614302 Src-transformed (Fibroblast Cells) 1