UCSF

Tyrosine-protein Kinase SRC, Mouse (23 Compounds)

Swissprot:
SRC_MOUSE
Stitch:
SRC_MOUSE
UniProt:
P05480
ChEMBL:
CHEMBL3074
Reactome:
REACT_259068
REACT_224600
REACT_204081
REACT_261568
REACT_248291
REACT_230639
REACT_243212
REACT_243590
REACT_258158
REACT_243939
REACT_257656
REACT_241951
REACT_196487
REACT_206286
REACT_245546
REACT_238268
REACT_246176
REACT_237796
REACT_253341
REACT_240371
REACT_207601
REACT_257923
REACT_227425
REACT_215628
REACT_242976
REACT_188191
REACT_188578
REACT_198526
REACT_220322
REACT_257088
REACT_245086
PDB:
Src

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 23 1 0 0
Binding ≤ 1μM 18 1 0 0

Reactome Network (31)

Reactome ID Description Species
REACT_259068 ADP signalling through P2Y purinoceptor 1 Mus musculus
REACT_224600 c-src mediated regulation of Cx43 function and closure of gap junctions Mus musculus
REACT_204081 CD28 co-stimulation Mus musculus
REACT_261568 CTLA4 inhibitory signaling Mus musculus
REACT_248291 DCC mediated attractive signaling Mus musculus
REACT_230639 Downstream signal transduction Mus musculus
REACT_243212 DSCAM interactions Mus musculus
REACT_243590 EPH-ephrin mediated repulsion of cells Mus musculus
REACT_258158 EPH-Ephrin signaling Mus musculus
REACT_243939 EPHA-mediated growth cone collapse Mus musculus
REACT_257656 EPHB-mediated forward signaling Mus musculus
REACT_241951 Ephrin signaling Mus musculus
REACT_196487 FCGR activation Mus musculus
REACT_206286 GAB1 signalosome Mus musculus
REACT_245546 GP1b-IX-V activation signalling Mus musculus
REACT_238268 GRB2:SOS provides linkage to MAPK signaling for Integrins Mus musculus
REACT_246176 Integrin alphaIIb beta3 signaling Mus musculus
REACT_237796 NCAM signaling for neurite out-growth Mus musculus
REACT_253341 Netrin mediated repulsion signals Mus musculus
REACT_240371 p130Cas linkage to MAPK signaling for integrins Mus musculus
REACT_207601 p38MAPK events Mus musculus
REACT_257923 Recycling pathway of L1 Mus musculus
REACT_227425 Regulation of KIT signaling Mus musculus
REACT_215628 Signal regulatory protein (SIRP) family interactions Mus musculus
REACT_242976 Signaling by EGFR Mus musculus
REACT_188191 Signaling by ERBB2 Mus musculus
REACT_188578 Signaling by SCF-KIT Mus musculus
REACT_198526 Spry regulation of FGF signaling Mus musculus
REACT_220322 Thrombin signalling through proteinase activated receptors (PARs) Mus musculus
REACT_257088 VEGFA-VEGFR2 Pathway Mus musculus
REACT_245086 VEGFR2 mediated cell proliferation Mus musculus
Uniprot Swissprot Chembl Description Number Shared
PGFRA_MOUSE P26618 CHEMBL3466 Platelet-derived Growth Factor Receptor Alpha, Mouse 23

GAB1 signalosome

Uniprot Swissprot Chembl Description Number Shared
CSK_MOUSE P41241 CHEMBL2333 Tyrosine-protein Kinase CSK, Mouse 1

Integrin alphaIIb beta3 signaling

Uniprot Swissprot Chembl Description Number Shared
CSK_MOUSE P41241 CHEMBL2333 Tyrosine-protein Kinase CSK, Mouse 1

NCAM signaling for neurite out-growth

Uniprot Swissprot Chembl Description Number Shared
FGFR1_MOUSE P16092 CHEMBL3960 Fibroblast Growth Factor Receptor 1, Mouse 21
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
SRC_CHICK P00523 CHEMBL3655 Tyrosine-protein Kinase SRC, Chick 195 15 1 5
SRC_HUMAN P12931 CHEMBL267 Tyrosine-protein Kinase SRC, Human 2,170 106 20 63
SRC_RAT Q9WUD9 CHEMBL3014 Tyrosine-protein Kinase SRC, Rat 28 1 1 0

Clustered By Gene (0)

Clustered By Organism (2)

Code Description Substances Purchasable Natural In Man
SRC-1-E Tyrosine-protein Kinase SRC (cluster #1 Of 3), Eukaryotic 2,249 107 20 50
SRC-2-E Tyrosine-protein Kinase SRC (cluster #2 Of 3), Eukaryotic 14 3 0 5
SRC-3-E Tyrosine-protein Kinase SRC (cluster #3 Of 3), Eukaryotic 93 1 1 9
Uniprot Swissprot Chembl Description Number Shared
PGFRA_MOUSE P26618 CHEMBL3466 Platelet-derived Growth Factor Receptor Alpha, Mouse 23
PGFRB_MOUSE P05622 CHEMBL2749 Platelet-derived Growth Factor Receptor Beta, Mouse 23
FGFR1_MOUSE P16092 CHEMBL3960 Fibroblast Growth Factor Receptor 1, Mouse 21
FGFR2_MOUSE P21803 CHEMBL3648 Fibroblast Growth Factor Receptor 2, Mouse 21
FGFR3_MOUSE Q61851 CHEMBL4066 Fibroblast Growth Factor Receptor 3, Mouse 21
FGFR4_MOUSE Q03142 CHEMBL3839 Fibroblast Growth Factor Receptor 4, Mouse 21
PGFRA_RAT P20786 CHEMBL2513 Platelet-derived Growth Factor Receptor Alpha, Rat 5
PGFRB_RAT Q05030 CHEMBL4125 Platelet-derived Growth Factor Receptor Beta, Rat 5
FGFR1_HUMAN P11362 CHEMBL3650 Fibroblast Growth Factor Receptor 1, Human 3
SRC_CHICK P00523 CHEMBL3655 Tyrosine-protein Kinase SRC, Chick 3
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 2
FGFR2_HUMAN P21802 CHEMBL4142 Fibroblast Growth Factor Receptor 2, Human 2
FGFR3_HUMAN P22607 CHEMBL2742 Fibroblast Growth Factor Receptor 3, Human 2
FGFR4_HUMAN P22455 CHEMBL3973 Fibroblast Growth Factor Receptor 4, Human 2
SRC_HUMAN P12931 CHEMBL267 Tyrosine-protein Kinase SRC, Human 2
CSK_MOUSE P41241 CHEMBL2333 Tyrosine-protein Kinase CSK, Mouse 1
WEE1_HUMAN P30291 CHEMBL5491 Serine/threonine-protein Kinase WEE1, Human 1