UCSF

Tyrosine-protein Kinase CSK, Mouse (69 Compounds)

Swissprot:
CSK_MOUSE
Stitch:
CSK_MOUSE
UniProt:
P41241
ChEMBL:
CHEMBL2333
Reactome:
REACT_206286
REACT_246176
REACT_263643
REACT_216080
PDB:
1JEG (DOCK)
Csk

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 69 1 0 0
Binding ≤ 1μM 59 1 0 0

Reactome Network (4)

Reactome ID Description Species
REACT_206286 GAB1 signalosome Mus musculus
REACT_246176 Integrin alphaIIb beta3 signaling Mus musculus
REACT_263643 PD-1 signaling Mus musculus
REACT_216080 Phosphorylation of CD3 and TCR zeta chains Mus musculus
Uniprot Swissprot Chembl Description Number Shared
SRC_MOUSE P05480 CHEMBL3074 Tyrosine-protein Kinase SRC, Mouse 1

Integrin alphaIIb beta3 signaling

Uniprot Swissprot Chembl Description Number Shared
SRC_MOUSE P05480 CHEMBL3074 Tyrosine-protein Kinase SRC, Mouse 1

PD-1 signaling

Uniprot Swissprot Chembl Description Number Shared
LCK_MOUSE P06240 CHEMBL2480 Tyrosine-protein Kinase LCK, Mouse 13

Phosphorylation of CD3 and TCR zeta chains

Uniprot Swissprot Chembl Description Number Shared
LCK_MOUSE P06240 CHEMBL2480 Tyrosine-protein Kinase LCK, Mouse 13
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
CSK_HUMAN P41240 CHEMBL2634 Tyrosine-protein Kinase CSK, Human 30 17 8 11
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
CSK21_MOUSE Q60737 CHEMBL3537 Casein Kinase II Alpha, Mouse 6 0 0 0

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
SRC_HUMAN P12931 CHEMBL267 Tyrosine-protein Kinase SRC, Human 69
WEE1_HUMAN P30291 CHEMBL5491 Serine/threonine-protein Kinase WEE1, Human 40
TIE2_HUMAN Q02763 CHEMBL4128 Tyrosine-protein Kinase TIE-2, Human 17
VGFR2_HUMAN P35968 CHEMBL279 Vascular Endothelial Growth Factor Receptor 2, Human 17
LCK_HUMAN P06239 CHEMBL258 Tyrosine-protein Kinase LCK, Human 14
LCK_MOUSE P06240 CHEMBL2480 Tyrosine-protein Kinase LCK, Mouse 13
FGFR1_HUMAN P11362 CHEMBL3650 Fibroblast Growth Factor Receptor 1, Human 4
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 3
INSR_HUMAN P06213 CHEMBL1981 Insulin Receptor, Human 3
PGFRA_HUMAN P16234 CHEMBL2007 Platelet-derived Growth Factor Receptor Alpha, Human 3
PGFRB_HUMAN P09619 CHEMBL1913 Platelet-derived Growth Factor Receptor Beta, Human 3
PGFRB_MOUSE P05622 CHEMBL2749 Platelet-derived Growth Factor Receptor Beta, Mouse 3
SRC_CHICK P00523 CHEMBL3655 Tyrosine-protein Kinase SRC, Chick 3
FGFR1_MOUSE P16092 CHEMBL3960 Fibroblast Growth Factor Receptor 1, Mouse 2
FGFR2_HUMAN P21802 CHEMBL4142 Fibroblast Growth Factor Receptor 2, Human 2
FGFR3_HUMAN P22607 CHEMBL2742 Fibroblast Growth Factor Receptor 3, Human 2
FGFR4_HUMAN P22455 CHEMBL3973 Fibroblast Growth Factor Receptor 4, Human 2
PGFRA_MOUSE P26618 CHEMBL3466 Platelet-derived Growth Factor Receptor Alpha, Mouse 2
CSF1R_HUMAN P07333 CHEMBL1844 Macrophage Colony Stimulating Factor Receptor, Human 1
FGFR2_MOUSE P21803 CHEMBL3648 Fibroblast Growth Factor Receptor 2, Mouse 1
FGFR3_MOUSE Q61851 CHEMBL4066 Fibroblast Growth Factor Receptor 3, Mouse 1
FGFR4_MOUSE Q03142 CHEMBL3839 Fibroblast Growth Factor Receptor 4, Mouse 1
PGFRA_RAT P20786 CHEMBL2513 Platelet-derived Growth Factor Receptor Alpha, Rat 1
PGFRB_RAT Q05030 CHEMBL4125 Platelet-derived Growth Factor Receptor Beta, Rat 1
SRC_MOUSE P05480 CHEMBL3074 Tyrosine-protein Kinase SRC, Mouse 1