ZINC 12

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Names
Compounds (0)
Reactome (0)
Related By:
Pathway (0)
Organism (-1)
Gene (-1)
Org. Clust. (-1)
ChEMBL (99)
Rings (17)

NIH3T3 (Fibroblasts) (510 Compounds)

Swissprot:: Z80951
Stitch:: Z80951
UniProt:: Z80951
ChEMBL:: CHEMBL614822

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	0	0	0	0
Binding ≤ 1μM	0	0	0	0
Functional ≤ 10μM	510	40	9	10
ADME/T ≤ 10μM	10	1	1	1

Clustered By Gene (0)

Uniprot	Swissprot	Chembl	Description	Number Shared
FNTA_MOUSE	Q61239	CHEMBL2153	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Mouse	76
FNTB_MOUSE	Q8K2I1	CHEMBL2631	Protein Farnesyltransferase Beta Subunit, Mouse	76
FNTA_HUMAN	P49354	CHEMBL271	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Human	62
FNTB_HUMAN	P49356	CHEMBL272	Protein Farnesyltransferase Beta Subunit, Human	62
EGFR_HUMAN	P00533	CHEMBL203	Epidermal Growth Factor Receptor ErbB1, Human	17
Z80166	Z80166	CHEMBL384	HT-29 (Colon Adenocarcinoma Cells)	17
Z81057	Z81057	CHEMBL613979	HUVEC (Umbilical Vein Endothelial Cells)	16
Z80224	Z80224	CHEMBL387	MCF7 (Breast Carcinoma Cells)	14
ERBB2_HUMAN	P04626	CHEMBL1824	Receptor Protein-tyrosine Kinase ErbB-2, Human	11
Z81247	Z81247	CHEMBL399	HeLa (Cervical Adenocarcinoma Cells)	11
PGFRA_RAT	P20786	CHEMBL2513	Platelet-derived Growth Factor Receptor Alpha, Rat	7
PGFRB_RAT	Q05030	CHEMBL4125	Platelet-derived Growth Factor Receptor Beta, Rat	7
Z50594	Z50594	CHEMBL375	Mus Musculus	7
Z80390	Z80390	CHEMBL390	PC-3 (Prostate Carcinoma Cells)	7
Z80742	Z80742	CHEMBL614657	C6 (Glioma Cells)	7
Z50425	Z50425	CHEMBL364	Plasmodium Falciparum	5
Z80152	Z80152	CHEMBL613510	HCT-8 (Ileocecal Adenocarcinoma)	5
Z81331	Z81331	CHEMBL612262	SW-620 (Colon Adenocarcinoma Cells)	5
PGFRA_MOUSE	P26618	CHEMBL3466	Platelet-derived Growth Factor Receptor Alpha, Mouse	4
PGFRB_MOUSE	P05622	CHEMBL2749	Platelet-derived Growth Factor Receptor Beta, Mouse	4
Z50587	Z50587	CHEMBL372	Homo Sapiens	4
APH1A_MOUSE	Q8BVF7	CHEMBL3787	Gamma-secretase Subunit APH-1A, Mouse	3
APH1B_MOUSE	Q8C7N7	CHEMBL3786	Gamma-secretase Subunit APH-1B, Mouse	3
NICA_MOUSE	P57716	CHEMBL4548	Nicastrin, Mouse	3
PEN2_MOUSE	Q9CQR7	CHEMBL4539	Gamma-secretase Subunit PEN-2, Mouse	3
PSN1_MOUSE	P49769	CHEMBL5128	Presenilin-1, Mouse	3
PSN2_MOUSE	Q61144	CHEMBL3483	Presenilin-2, Mouse	3
Z50466	Z50466	CHEMBL368	Trypanosoma Cruzi	3
Z80120	Z80120	CHEMBL614285	DLD-1 (Colon Adenocarcinoma Cells)	3
Z80125	Z80125	CHEMBL613508	DU-145 (Prostate Carcinoma)	3
Z80156	Z80156	CHEMBL383	HL-60 (Promyeloblast Leukemia Cells)	3
Z80193	Z80193	CHEMBL386	L1210 (Lymphocytic Leukemia Cells)	3
Z80682	Z80682	CHEMBL392	A549 (Lung Carcinoma Cells)	3
Z80852	Z80852	CHEMBL614069	A-431 (Epidermoid Carcinoma Cells)	3
ANDR_HUMAN	P10275	CHEMBL1871	Androgen Receptor, Human	2
GCR_MOUSE	P06537	CHEMBL3144	Glucocorticoid Receptor, Mouse	2
NMDE2_RAT	Q00960	CHEMBL311	Glutamate [NMDA] Receptor Subunit Epsilon 2, Rat	2
NMDZ1_RAT	P35439	CHEMBL330	Glutamate (NMDA) Receptor Subunit Zeta 1, Rat	2
PRGR_HUMAN	P06401	CHEMBL208	Progesterone Receptor, Human	2
RASH_HUMAN	P01112	CHEMBL2167	Transforming Protein P21/H-Ras-1, Human	2
Z80035	Z80035	CHEMBL381	B16 (Melanoma Cells)	2
Z80110	Z80110	CHEMBL613507	CV-1 (Kidney Cells)	2
Z80491	Z80491	CHEMBL614163	SK-N-MC (Neuroepithelioma Cells)	2
Z80565	Z80565	CHEMBL614247	U-87 MG (Glioblastoma Cells)	2
Z80936	Z80936	CHEMBL614818	HEK293 (Embryonic Kidney Fibroblasts)	2
Z81020	Z81020	CHEMBL395	HepG2 (Hepatoblastoma Cells)	2
Z81115	Z81115	CHEMBL398	KB (Squamous Cell Carcinoma)	2
A4_HUMAN	P05067	CHEMBL2487	Beta Amyloid A4 Protein, Human	1
ESR1_HUMAN	P03372	CHEMBL206	Estrogen Receptor Alpha, Human	1
ESR2_HUMAN	Q92731	CHEMBL242	Estrogen Receptor Beta, Human	1
GCR_HUMAN	P04150	CHEMBL2034	Glucocorticoid Receptor, Human	1
GCR_RAT	P06536	CHEMBL3368	Glucocorticoid Receptor, Rat	1
MCR_HUMAN	P08235	CHEMBL1994	Mineralocorticoid Receptor, Human	1
MDR1_HUMAN	P08183	CHEMBL4302	P-glycoprotein 1, Human	1
MDR1_MOUSE	P06795	CHEMBL3467	P-glycoprotein 1, Mouse	1
MDR3_MOUSE	P21447	CHEMBL2573	P-glycoprotein 3, Mouse	1
SRC_HUMAN	P12931	CHEMBL267	Tyrosine-protein Kinase SRC, Human	1
TGFR1_HUMAN	P36897	CHEMBL4439	TGF-beta Receptor Type I, Human	1
TGFR2_HUMAN	P37173	CHEMBL4267	TGF-beta Receptor Type II, Human	1
VP16_HHV11	P06492	CHEMBL4218	Alpha Trans-inducing Protein (VP16), Hhv11	1
Z50380	Z50380	CHEMBL613088	Mycobacterium Smegmatis	1
Z50426	Z50426	CHEMBL612856	Plasmodium Falciparum (isolate K1 / Thailand)	1
Z50597	Z50597	CHEMBL376	Rattus Norvegicus	1
Z80017	Z80017	CHEMBL614023	A2780cisR (Cisplatin-resistant Ovarian Carcinoma Cells)	1
Z80055	Z80055	CHEMBL614067	CAKI-1 (Kidney Carcinoma Cells)	1
Z80088	Z80088	CHEMBL613853	CHO (Ovarian Cells)	1
Z80089	Z80089	CHEMBL614555	CHO-AA8	1
Z80106	Z80106	CHEMBL614563	COS-1 (Kidney Cells)	1
Z80114	Z80114	CHEMBL614281	Daudi (Burkitts Lymphoma Cells)	1
Z80115	Z80115	CHEMBL612702	DC3F	1
Z80117	Z80117	CHEMBL614283	DC3F/AD-II	1
Z80164	Z80164	CHEMBL614580	HT-1080 (Fibrosarcoma Cells)	1
Z80186	Z80186	CHEMBL385	K562 (Erythroleukemia Cells)	1
Z80211	Z80211	CHEMBL614721	LoVo (Colon Adenocarcinoma Cells)	1
Z80244	Z80244	CHEMBL614335	MDA-MB-468 (Breast Adenocarcinoma)	1
Z80362	Z80362	CHEMBL389	P388 (Lymphoma Cells)	1
Z80364	Z80364	CHEMBL614218	P388/ADR (Lymphoma Cells)	1
Z80367	Z80367	CHEMBL614220	P388/S	1
Z80416	Z80416	CHEMBL614630	Rat1 (Fibroblast Cells)	1
Z80433	Z80433	CHEMBL614882	RPMI-8226 (Multiple Myeloma Cells)	1
Z80472	Z80472	CHEMBL612542	SiHa (Cervical Squamous Cell Carcinoma)	1
Z80475	Z80475	CHEMBL613834	SK-BR-3 (Breast Adenocarcinoma)	1
Z80493	Z80493	CHEMBL614925	SK-OV-3 (Ovarian Carcinoma Cells)	1
Z80526	Z80526	CHEMBL612544	SW480 (Colon Adenocarcinoma Cells)	1
Z80583	Z80583	CHEMBL391	Vero (Kidney Cells)	1
Z80647	Z80647	CHEMBL613103	833K Cell Line	1
Z80712	Z80712	CHEMBL614361	T47D (Breast Carcinoma Cells)	1
Z80768	Z80768	CHEMBL614455	CH1 (Ovarian Carcinoma Cells)	1
Z80776	Z80776	CHEMBL612246	Clone 62 Cell Line	1
Z80784	Z80784	CHEMBL614462	Col2 (Colon Carcinoma Cells)	1
Z80888	Z80888	CHEMBL614669	H2987 Cell Line	1
Z80928	Z80928	CHEMBL394	HCT-116 (Colon Carcinoma Cells)	1
Z80954	Z80954	CHEMBL614071	HFF (Foreskin Fibroblasts)	1
Z81017	Z81017	CHEMBL614647	WiDr (Colon Adenocarcinoma Cells)	1
Z81034	Z81034	CHEMBL614004	A2780 (Ovarian Carcinoma Cells)	1
Z81264	Z81264	CHEMBL614074	V79 (Lung Fibroblasts)	1
Z81285	Z81285	CHEMBL615000	NIH-H Cell Line	1
Z81286	Z81286	CHEMBL615001	NIH-K Cell Line	1
Z81335	Z81335	CHEMBL612263	HCT-15 (Colon Adenocarcinoma Cells)	1