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Identity
99%
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Substructure
5,6-dihydro-4H-pyrrolo[2,1-e]pyrazole
PubMed
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SMILES:
Ring Information
Rings
Ring Systems
Atoms
Carbons
Nitrogens
Oxygens
Sulfurs
2
1
8
6
2
0
0
Subset Information
Substances
Natural
Purchasable
Annotated
BB
In Man
Last Updated
View
0
0
18
0
0
2012-03-22
Parents (
2 Total
)
1H-pyrazole
1-pyrroline
Children (
8 Total
)
5-[2-(2-pyridyl)-5,6-dihydro-4H-…
6-[2-(2-pyridyl)-5,6-dihydro-4H-…
5-[2-(2-pyridyl)-5,6-dihydro-4H-…
6-[2-(2-pyridyl)-5,6-dihydro-4H-…
1-(3-piperidinopropyl)-6-[2-(2-p…
5-[2-(2-pyridyl)-5,6-dihydro-4H-…
7-(2-piperazinoethoxy)-4-[2-(2-p…
7-(3-piperazinopropoxy)-4-[2-(2-…
Most Common Targets
Name
(Uniprot)
Swissprot
ChEMBL
Description
Size
Browse
Download
(Annotations)
TGFR1_HUMAN
P36897
CHEMBL4439
TGF-beta Receptor Type I, Human
18
Annotations
Catalogs
SMILES
SDF
Mol2
Flexibase
TGFR1_HUMAN
P36897
CHEMBL4439
TGF-beta Receptor Type I, Human
14
Annotations
Catalogs
SMILES
SDF
Mol2
Flexibase
TGFR2_HUMAN
P37173
CHEMBL4267
TGF-beta Receptor Type II, Human
12
Annotations
Catalogs
SMILES
SDF
Mol2
Flexibase
TGFR1_HUMAN
P36897
CHEMBL4439
TGF-beta Receptor Type I, Human
10
Annotations
Catalogs
SMILES
SDF
Mol2
Flexibase
TGFR2_HUMAN
P37173
CHEMBL4267
TGF-beta Receptor Type II, Human
5
Annotations
Catalogs
SMILES
SDF
Mol2
Flexibase
MLTK_HUMAN
Q9NYL2
CHEMBL3886
Mixed Lineage Kinase 7, Human
4
Annotations
Catalogs
SMILES
SDF
Mol2
Flexibase
TGFR2_HUMAN
P37173
CHEMBL4267
TGF-beta Receptor Type II, Human
3
Annotations
Catalogs
SMILES
SDF
Mol2
Flexibase
Z50594
Z50594
CHEMBL375
Mus Musculus
2
Annotations
Catalogs
SMILES
SDF
Mol2
Flexibase
Z80951
Z80951
CHEMBL614822
NIH3T3 (Fibroblasts)
2
Annotations
Catalogs
SMILES
SDF
Mol2
Flexibase
MLTK_HUMAN
Q9NYL2
CHEMBL3886
Mixed Lineage Kinase 7, Human
1
Annotations
Catalogs
SMILES
SDF
Mol2
Flexibase
![Image of 5,6-dihydro-4H-pyrrolo[2,1-e]pyrazole](http://zinc12.docking.org/img/rings/139240.gif)
![5-[2-(2-pyridyl)-5,6-dihydro-4H-pyrrolo[2,1-e]pyrazol-3-yl]-1H-benzimidazole](http://zinc12.docking.org/img/rings/226413.gif)
![6-[2-(2-pyridyl)-5,6-dihydro-4H-pyrrolo[2,1-e]pyrazol-3-yl]-1H-benzimidazole](http://zinc12.docking.org/img/rings/226422.gif)
![5-[2-(2-pyridyl)-5,6-dihydro-4H-pyrrolo[2,1-e]pyrazol-3-yl]-1H-indole](http://zinc12.docking.org/img/rings/226401.gif)
![6-[2-(2-pyridyl)-5,6-dihydro-4H-pyrrolo[2,1-e]pyrazol-3-yl]-1-(3-pyrrolidinopropyl)benzimidazole](http://zinc12.docking.org/img/rings/226439.gif)
![1-(3-piperidinopropyl)-6-[2-(2-pyridyl)-5,6-dihydro-4H-pyrrolo[2,1-e]pyrazol-3-yl]benzimidazole](http://zinc12.docking.org/img/rings/226434.gif)
![5-[2-(2-pyridyl)-5,6-dihydro-4H-pyrrolo[2,1-e]pyrazol-3-yl]-1-(3-tetrahydropyran-2-yloxypropyl)benzimidazole](http://zinc12.docking.org/img/rings/226449.gif)
![7-(2-piperazinoethoxy)-4-[2-(2-pyridyl)-5,6-dihydro-4H-pyrrolo[2,1-e]pyrazol-3-yl]quinoline](http://zinc12.docking.org/img/rings/139242.gif)
![7-(3-piperazinopropoxy)-4-[2-(2-pyridyl)-5,6-dihydro-4H-pyrrolo[2,1-e]pyrazol-3-yl]quinoline](http://zinc12.docking.org/img/rings/139238.gif)