UCSF

TGF-beta Receptor Type II, Human (18 Compounds)

Swissprot:
TGFR2_HUMAN
Stitch:
TGFR2_HUMAN
UniProt:
P37173
ChEMBL:
CHEMBL4267
Reactome:
REACT_120727
REACT_169165
REACT_169103
REACT_120850
REACT_120726
REACT_169263
REACT_169445
REACT_169440
REACT_169192
PDB:
1KTZ (DOCK)
1M9Z (DOCK)
1PLO (DOCK)
2PJY (DOCK)
3KFD (DOCK)
TGFBR2

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 18 7 3 5
Binding ≤ 1μM 7 2 1 2
Functional ≤ 10μM 17 1 0 1

Reactome Network (9)

Reactome ID Description Species
REACT_120727 Downregulation of TGF-beta receptor signaling Homo sapiens
REACT_169165 SMAD2/3 MH2 Domain Mutants in Cancer Homo sapiens
REACT_169103 SMAD2/3 Phosphorylation Motif Mutants in Cancer Homo sapiens
REACT_120850 TGF-beta receptor signaling activates SMADs Homo sapiens
REACT_120726 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) Homo sapiens
REACT_169263 TGFBR1 KD Mutants in Cancer Homo sapiens
REACT_169445 TGFBR1 LBD Mutants in Cancer Homo sapiens
REACT_169440 TGFBR2 Kinase Domain Mutants in Cancer Homo sapiens
REACT_169192 TGFBR2 MSI Frameshift Mutants in Cancer Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
TGFR1_HUMAN P36897 CHEMBL4439 TGF-beta Receptor Type I, Human 21

SMAD2/3 MH2 Domain Mutants in Cancer

Uniprot Swissprot Chembl Description Number Shared
TGFR1_HUMAN P36897 CHEMBL4439 TGF-beta Receptor Type I, Human 21

SMAD2/3 Phosphorylation Motif Mutants in Cancer

Uniprot Swissprot Chembl Description Number Shared
TGFR1_HUMAN P36897 CHEMBL4439 TGF-beta Receptor Type I, Human 21

TGF-beta receptor signaling activates SMADs

Uniprot Swissprot Chembl Description Number Shared
TGFR1_HUMAN P36897 CHEMBL4439 TGF-beta Receptor Type I, Human 21

TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)

Uniprot Swissprot Chembl Description Number Shared
KPCZ_HUMAN Q05513 CHEMBL3438 Protein Kinase C Zeta, Human 1
TGFR1_HUMAN P36897 CHEMBL4439 TGF-beta Receptor Type I, Human 21

TGFBR1 KD Mutants in Cancer

Uniprot Swissprot Chembl Description Number Shared
TGFR1_HUMAN P36897 CHEMBL4439 TGF-beta Receptor Type I, Human 21

TGFBR1 LBD Mutants in Cancer

Uniprot Swissprot Chembl Description Number Shared
TGFR1_HUMAN P36897 CHEMBL4439 TGF-beta Receptor Type I, Human 21

TGFBR2 Kinase Domain Mutants in Cancer

Uniprot Swissprot Chembl Description Number Shared
TGFR1_HUMAN P36897 CHEMBL4439 TGF-beta Receptor Type I, Human 21
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
TGFR1_HUMAN P36897 CHEMBL4439 TGF-beta Receptor Type I, Human 402 22 3 9

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
TGFR1_HUMAN P36897 CHEMBL4439 TGF-beta Receptor Type I, Human 21
MLTK_HUMAN Q9NYL2 CHEMBL3886 Mixed Lineage Kinase 7, Human 10
GAK_HUMAN O14976 CHEMBL4355 Serine/threonine-protein Kinase GAK, Human 7
GSK3B_HUMAN P49841 CHEMBL262 Glycogen Synthase Kinase-3 Beta, Human 7
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 6
STK36_HUMAN Q9NRP7 CHEMBL4312 Serine/threonine-protein Kinase 36, Human 6
TNI3K_HUMAN Q59H18 CHEMBL5260 Serine/threonine-protein Kinase TNNI3K, Human 6
CDK2_HUMAN P24941 CHEMBL301 Cyclin-dependent Kinase 2, Human 5
CTRO_HUMAN O14578 CHEMBL5579 Citron Rho-interacting Kinase, Human 5
DDR1_HUMAN Q08345 CHEMBL5319 Epithelial Discoidin Domain-containing Receptor 1, Human 5
EPHB2_HUMAN P29323 CHEMBL3290 Ephrin Type-B Receptor 2, Human 5
FLT3_HUMAN P36888 CHEMBL1974 Tyrosine-protein Kinase Receptor FLT3, Human 5
FRK_HUMAN P42685 CHEMBL4223 Tyrosine-protein Kinase FRK, Human 5
KC1E_HUMAN P49674 CHEMBL4937 Casein Kinase I Epsilon, Human 5
LCK_HUMAN P06239 CHEMBL258 Tyrosine-protein Kinase LCK, Human 5
MK10_HUMAN P53779 CHEMBL2637 C-Jun N-terminal Kinase 3, Human 5
MK14_HUMAN Q16539 CHEMBL260 MAP Kinase P38 Alpha, Human 5
RAF1_HUMAN P04049 CHEMBL1906 Serine/threonine-protein Kinase RAF, Human 5
RIPK2_HUMAN O43353 CHEMBL5014 Serine/threonine-protein Kinase RIPK2, Human 5
SLK_HUMAN Q9H2G2 CHEMBL4202 Serine/threonine-protein Kinase 2, Human 5
SRC_HUMAN P12931 CHEMBL267 Tyrosine-protein Kinase SRC, Human 5
ABL2_HUMAN P42684 CHEMBL4014 Tyrosine-protein Kinase ABL2, Human 4
BRAF_HUMAN P15056 CHEMBL5145 Serine/threonine-protein Kinase B-raf, Human 4
CDK4_HUMAN P11802 CHEMBL331 Cyclin-dependent Kinase 4, Human 4
DDR2_HUMAN Q16832 CHEMBL5122 Discoidin Domain-containing Receptor 2, Human 4
EPHA3_HUMAN P29320 CHEMBL4954 Ephrin Type-A Receptor 3, Human 4
EPHA5_HUMAN P54756 CHEMBL3987 Ephrin Type-A Receptor 5, Human 4
EPHA6_HUMAN Q9UF33 CHEMBL4526 Ephrin Type-A Receptor 6, Human 4
EPHB1_HUMAN P54762 CHEMBL5072 Ephrin Type-B Receptor 1, Human 4
GSK3A_HUMAN P49840 CHEMBL2850 Glycogen Synthase Kinase-3 Alpha, Human 4
KC1D_HUMAN P48730 CHEMBL2828 Casein Kinase I Delta, Human 4
KIT_HUMAN P10721 CHEMBL1936 Stem Cell Growth Factor Receptor, Human 4
KPCB_HUMAN P05771 CHEMBL3045 Protein Kinase C Beta, Human 4
KS6A1_HUMAN Q15418 CHEMBL2553 Ribosomal Protein S6 Kinase Alpha 1, Human 4
KS6A6_HUMAN Q9UK32 CHEMBL4924 Ribosomal Protein S6 Kinase Alpha 6, Human 4
M4K4_HUMAN O95819 CHEMBL6166 Mitogen-activated Protein Kinase Kinase Kinase Kinase 4, Human 4
MK09_HUMAN P45984 CHEMBL4179 C-Jun N-terminal Kinase 2, Human 4
MK11_HUMAN Q15759 CHEMBL3961 MAP Kinase P38 Beta, Human 4
MK12_HUMAN P53778 CHEMBL4674 MAP Kinase P38 Gamma, Human 4
MP2K2_HUMAN P36507 CHEMBL2964 Dual Specificity Mitogen-activated Protein Kinase Kinase 2, Human 4
MRCKA_HUMAN Q5VT25 CHEMBL4516 Serine/threonine-protein Kinase MRCK-A, Human 4
MRCKB_HUMAN Q9Y5S2 CHEMBL5052 Serine/threonine-protein Kinase MRCK Beta, Human 4
NLK_HUMAN Q9UBE8 CHEMBL5364 Serine/threonine Protein Kinase NLK, Human 4
PTK6_HUMAN Q13882 CHEMBL4601 Tyrosine-protein Kinase BRK, Human 4
SRMS_HUMAN Q9H3Y6 CHEMBL5703 Tyrosine-protein Kinase Srms, Human 4
TNIK_HUMAN Q9UKE5 CHEMBL4527 TRAF2- And NCK-interacting Kinase, Human 4
TXK_HUMAN P42681 CHEMBL4367 Tyrosine-protein Kinase TXK, Human 4
ABL1_HUMAN P00519 CHEMBL1862 Tyrosine-protein Kinase ABL, Human 3
ACV1B_HUMAN P36896 CHEMBL5310 Activin Receptor Type-1B, Human 3
ACVR1_HUMAN Q04771 CHEMBL5903 Activin Receptor Type-1, Human 3
ADCK4_HUMAN Q96D53 CHEMBL5753 Uncharacterized AarF Domain-containing Protein Kinase 4, Human 3
BLK_HUMAN P51451 CHEMBL2250 Tyrosine-protein Kinase BLK, Human 3
CDK14_HUMAN O94921 CHEMBL6162 Serine/threonine-protein Kinase PFTAIRE-1, Human 3
CDK16_HUMAN Q00536 CHEMBL4597 Serine/threonine-protein Kinase PCTAIRE-1, Human 3
CDK17_HUMAN Q00537 CHEMBL5790 Serine/threonine-protein Kinase PCTAIRE-2, Human 3
CDK18_HUMAN Q07002 CHEMBL5316 Serine/threonine-protein Kinase PCTAIRE-3, Human 3
CDK19_HUMAN Q9BWU1 CHEMBL6002 Cell Division Cycle 2-like Protein Kinase 6, Human 3
CDK3_HUMAN Q00526 CHEMBL4442 Cyclin-dependent Kinase 3, Human 3
CDK5_HUMAN Q00535 CHEMBL4036 Cyclin-dependent Kinase 5, Human 3
CDK7_HUMAN P50613 CHEMBL3055 Cyclin-dependent Kinase 7, Human 3
CDK8_HUMAN P49336 CHEMBL5719 Cell Division Protein Kinase 8, Human 3
CDK9_HUMAN P50750 CHEMBL3116 Cyclin-dependent Kinase 9, Human 3
CLK1_HUMAN P49759 CHEMBL4224 Dual Specificty Protein Kinase CLK1, Human 3
CLK2_HUMAN P49760 CHEMBL4225 Dual Specificity Protein Kinase CLK2, Human 3
CSF1R_HUMAN P07333 CHEMBL1844 Macrophage Colony Stimulating Factor Receptor, Human 3
CSK_HUMAN P41240 CHEMBL2634 Tyrosine-protein Kinase CSK, Human 3
EPHA2_HUMAN P29317 CHEMBL2068 Ephrin Type-A Receptor 2, Human 3
EPHA4_HUMAN P54764 CHEMBL3988 Ephrin Type-A Receptor 4, Human 3
EPHA8_HUMAN P29322 CHEMBL4134 Ephrin Type-A Receptor 8, Human 3
FGR_HUMAN P09769 CHEMBL4454 Tyrosine-protein Kinase FGR, Human 3
HCK_HUMAN P08631 CHEMBL3234 Tyrosine-protein Kinase HCK, Human 3
KPCD1_HUMAN Q15139 CHEMBL3863 Protein Kinase C Mu, Human 3
KPCD2_HUMAN Q9BZL6 CHEMBL4900 Serine/threonine-protein Kinase D2, Human 3
KPCD3_HUMAN O94806 CHEMBL2595 Protein Kinase C Nu, Human 3
LYN_HUMAN P07948 CHEMBL3905 Tyrosine-protein Kinase Lyn, Human 3
M4K1_HUMAN Q92918 CHEMBL5749 Mitogen-activated Protein Kinase Kinase Kinase Kinase 1, Human 3
M4K3_HUMAN Q8IVH8 CHEMBL5432 Mitogen-activated Protein Kinase Kinase Kinase Kinase 3, Human 3
M4K5_HUMAN Q9Y4K4 CHEMBL4852 Mitogen-activated Protein Kinase Kinase Kinase Kinase 5, Human 3
MK08_HUMAN P45983 CHEMBL2276 C-Jun N-terminal Kinase 1, Human 3
MK13_HUMAN O15264 CHEMBL2939 MAP Kinase P38 Delta, Human 3
MK15_HUMAN Q8TD08 CHEMBL5198 Mitogen-activated Protein Kinase 15, Human 3
MKNK1_HUMAN Q9BUB5 CHEMBL4718 MAP Kinase-interacting Serine/threonine-protein Kinase MNK1, Human 3
MKNK2_HUMAN Q9HBH9 CHEMBL4204 MAP Kinase Signal-integrating Kinase 2, Human 3
MRCKG_HUMAN Q6DT37 CHEMBL5615 Serine/threonine-protein Kinase MRCK Gamma, Human 3
PGFRA_HUMAN P16234 CHEMBL2007 Platelet-derived Growth Factor Receptor Alpha, Human 3
PGFRB_HUMAN P09619 CHEMBL1913 Platelet-derived Growth Factor Receptor Beta, Human 3
RET_HUMAN P07949 CHEMBL2041 Tyrosine-protein Kinase Receptor RET, Human 3
STK10_HUMAN O94804 CHEMBL3981 Serine/threonine-protein Kinase 10, Human 3
TESK1_HUMAN Q15569 CHEMBL5604 Dual Specificity Testis-specific Protein Kinase 1, Human 3
TTK_HUMAN P33981 CHEMBL3983 Dual Specificity Protein Kinase TTK, Human 3
UFO_HUMAN P30530 CHEMBL4895 Tyrosine-protein Kinase Receptor UFO, Human 3
YES_HUMAN P07947 CHEMBL2073 Tyrosine-protein Kinase YES, Human 3
AAPK1_HUMAN Q13131 CHEMBL4045 AMP-activated Protein Kinase, Alpha-1 Subunit, Human 2
ADCK3_HUMAN Q8NI60 CHEMBL5550 Chaperone Activity Of Bc1 Complex-like, Mitochondrial, Human 2
ALK_HUMAN Q9UM73 CHEMBL4247 ALK Tyrosine Kinase Receptor, Human 2
AURKB_HUMAN Q96GD4 CHEMBL2185 Serine/threonine-protein Kinase Aurora-B, Human 2
AURKC_HUMAN Q9UQB9 CHEMBL3935 Serine/threonine-protein Kinase Aurora-C, Human 2
AVR2B_HUMAN Q13705 CHEMBL5466 Activin Receptor Type-2B, Human 2
BMX_HUMAN P51813 CHEMBL3834 Tyrosine-protein Kinase BMX, Human 2
BTK_HUMAN Q06187 CHEMBL5251 Tyrosine-protein Kinase BTK, Human 2
CCNB1_HUMAN P14635 CHEMBL2412 G2/mitotic-specific Cyclin B1, Human 2
CCNB2_HUMAN O95067 CHEMBL3723 G2/mitotic-specific Cyclin B2, Human 2
CCNB3_HUMAN Q8WWL7 CHEMBL3606 G2/mitotic-specific Cyclin B3, Human 2
CCND1_HUMAN P24385 CHEMBL3610 G1/S-specific Cyclin D1, Human 2
CCND2_HUMAN P30279 CHEMBL3613 G1/S-specific Cyclin D2, Human 2
CCND3_HUMAN P30281 CHEMBL2422 G1/S-specific Cyclin D3, Human 2
CCNE1_HUMAN P24864 CHEMBL3617 G1/S-specific Cyclin E1, Human 2
CCNE2_HUMAN O96020 CHEMBL2884 G1/S-specific Cyclin E2, Human 2
CD11A_HUMAN Q9UQ88 CHEMBL5416 PITSLRE Serine/threonine-protein Kinase CDC2L2, Human 2
CD11B_HUMAN P21127 CHEMBL5808 PITSLRE Serine/threonine-protein Kinase CDC2L1, Human 2
CDK1_HUMAN P06493 CHEMBL308 Cyclin-dependent Kinase 1, Human 2
CLK4_HUMAN Q9HAZ1 CHEMBL4203 Dual Specificity Protein Kinase CLK4, Human 2
DCLK1_HUMAN O15075 CHEMBL5683 Serine/threonine-protein Kinase DCLK1, Human 2
DCLK3_HUMAN Q9C098 CHEMBL6123 Serine/threonine-protein Kinase DCLK3, Human 2
DMPK_HUMAN Q09013 CHEMBL5320 Myotonin-protein Kinase, Human 2
DYR1B_HUMAN Q9Y463 CHEMBL5543 Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1B, Human 2
E2AK2_HUMAN P19525 CHEMBL5785 Interferon-induced, Double-stranded RNA-activated Protein Kinase, Human 2
EPHA1_HUMAN P21709 CHEMBL5810 Ephrin Type-A Receptor 1, Human 2
EPHA7_HUMAN Q15375 CHEMBL4602 Ephrin Type-A Receptor 7, Human 2
EPHB4_HUMAN P54760 CHEMBL5147 Ephrin Type-B Receptor 4, Human 2
ERBB2_HUMAN P04626 CHEMBL1824 Receptor Protein-tyrosine Kinase ErbB-2, Human 2
FGFR1_HUMAN P11362 CHEMBL3650 Fibroblast Growth Factor Receptor 1, Human 2
FGFR2_HUMAN P21802 CHEMBL4142 Fibroblast Growth Factor Receptor 2, Human 2
FYN_HUMAN P06241 CHEMBL1841 Tyrosine-protein Kinase FYN, Human 2
IRAK3_HUMAN Q9Y616 CHEMBL5081 Interleukin-1 Receptor-associated Kinase 3, Human 2
ITK_HUMAN Q08881 CHEMBL2959 Tyrosine-protein Kinase ITK/TSK, Human 2
JAK2_HUMAN O60674 CHEMBL2971 Tyrosine-protein Kinase JAK2, Human 2
JAK3_HUMAN P52333 CHEMBL2148 Tyrosine-protein Kinase JAK3, Human 2
KC1AL_HUMAN Q8N752 CHEMBL5520 Casein Kinase I Isoform Alpha-like, Human 2
KCC4_HUMAN Q16566 CHEMBL2494 CaM Kinase IV, Human 2
KKCC1_HUMAN Q8N5S9 CHEMBL5256 CaM-kinase Kinase Alpha, Human 2
KKCC2_HUMAN Q96RR4 CHEMBL5284 CaM-kinase Kinase Beta, Human 2
KPCT_HUMAN Q04759 CHEMBL3920 Protein Kinase C Theta, Human 2
KS6A2_HUMAN Q15349 CHEMBL3906 Ribosomal Protein S6 Kinase Alpha 2, Human 2
KS6A4_HUMAN O75676 CHEMBL3125 Ribosomal Protein S6 Kinase Alpha 4, Human 2
KS6A5_HUMAN O75582 CHEMBL4237 Ribosomal Protein S6 Kinase Alpha 5, Human 2
KSYK_HUMAN P43405 CHEMBL2599 Tyrosine-protein Kinase SYK, Human 2
LTK_HUMAN P29376 CHEMBL5627 Leukocyte Tyrosine Kinase Receptor, Human 2
M3K4_HUMAN Q9Y6R4 CHEMBL4853 Mitogen-activated Protein Kinase Kinase Kinase 4, Human 2
MELK_HUMAN Q14680 CHEMBL4578 Maternal Embryonic Leucine Zipper Kinase, Human 2
MERTK_HUMAN Q12866 CHEMBL5331 Proto-oncogene Tyrosine-protein Kinase MER, Human 2
MET_HUMAN P08581 CHEMBL3717 Hepatocyte Growth Factor Receptor, Human 2
MK06_HUMAN Q16659 CHEMBL5121 Mitogen-activated Protein Kinase 6, Human 2
MK07_HUMAN Q13164 CHEMBL5332 Mitogen-activated Protein Kinase 7, Human 2
MK14_MOUSE P47811 CHEMBL2336 MAP Kinase P38 Alpha, Mouse 2
MP2K1_HUMAN Q02750 CHEMBL3587 Dual Specificity Mitogen-activated Protein Kinase Kinase 1, Human 2
MYLK2_HUMAN Q9H1R3 CHEMBL2777 Myosin Light Chain Kinase 2, Human 2
NUAK2_HUMAN Q9H093 CHEMBL5698 NUAK Family SNF1-like Kinase 2, Human 2
PGH1_HUMAN P23219 CHEMBL221 Cyclooxygenase-1, Human 2
PHKG1_HUMAN Q16816 CHEMBL4004 Phosphorylase Kinase Gamma Subunit 1, Human 2
Q5SC61_TOXGO Q5SC61 CHEMBL6051 Mitogen-activated Protein Kinase 1, Toxgo 2
SIK1_HUMAN P57059 CHEMBL6082 Serine/threonine-protein Kinase SIK1, Human 2
SIK2_HUMAN Q9H0K1 CHEMBL5699 Serine/threonine-protein Kinase SIK2, Human 2
ST17A_HUMAN Q9UEE5 CHEMBL4525 Serine/threonine-protein Kinase 17A, Human 2
ST32B_HUMAN Q9NY57 CHEMBL5912 Serine/threonine-protein Kinase 32B, Human 2
STK33_HUMAN Q9BYT3 CHEMBL6005 Serine/threonine-protein Kinase 33, Human 2
STK3_HUMAN Q13188 CHEMBL4708 Serine/threonine-protein Kinase MST2, Human 2
TBA1A_RAT P68370 CHEMBL4139 Tubulin Alpha-1 Chain, Rat 2
TEC_HUMAN P42680 CHEMBL4246 Tyrosine-protein Kinase TEC, Human 2
TIE1_HUMAN P35590 CHEMBL5274 Tyrosine-protein Kinase Receptor Tie-1, Human 2
VGFR1_HUMAN P17948 CHEMBL1868 Vascular Endothelial Growth Factor Receptor 1, Human 2
VGFR2_HUMAN P35968 CHEMBL279 Vascular Endothelial Growth Factor Receptor 2, Human 2
AAK1_HUMAN Q2M2I8 CHEMBL3830 Adaptor-associated Kinase, Human 1
ACK1_HUMAN Q07912 CHEMBL4599 Tyrosine Kinase Non-receptor Protein 2, Human 1
ACVL1_HUMAN P37023 CHEMBL5311 Serine/threonine-protein Kinase Receptor R3, Human 1
ANKK1_HUMAN Q8NFD2 CHEMBL5547 Ankyrin Repeat And Protein Kinase Domain-containing Protein 1, Human 1
AURKA_HUMAN O14965 CHEMBL4722 Serine/threonine-protein Kinase Aurora-A, Human 1
AVR2A_HUMAN P27037 CHEMBL5616 Activin Receptor Type-2A, Human 1
BCR_HUMAN P11274 CHEMBL5146 Breakpoint Cluster Region Protein, Human 1
BLK_MOUSE P16277 CHEMBL3343 Tyrosine-protein Kinase BLK, Mouse 1
BMP2K_HUMAN Q9NSY1 CHEMBL4522 BMP-2-inducible Protein Kinase, Human 1
CCNA1_HUMAN P78396 CHEMBL3609 Cyclin A1, Human 1
CCNA2_HUMAN P20248 CHEMBL2582 Cyclin A2, Human 1
CCNB_MARGL P15206 CHEMBL4260 G2/mitotic-specific Cyclin B, Margl 1
CCNH_HUMAN P51946 CHEMBL2165 Cyclin H, Human 1
CDK6_HUMAN Q00534 CHEMBL2508 Cyclin-dependent Kinase 6, Human 1
CLK3_HUMAN P49761 CHEMBL4226 Dual Specificity Protein Kinase CLK3, Human 1
DAPK3_HUMAN O43293 CHEMBL2468 Death-associated Protein Kinase 3, Human 1
DCLK2_HUMAN Q8N568 CHEMBL5519 Serine/threonine-protein Kinase DCLK2, Human 1
E2AK4_HUMAN Q9P2K8 CHEMBL5358 Eukaryotic Translation Initiation Factor 2-alpha Kinase 4, Human 1
EPHB3_HUMAN P54753 CHEMBL4901 Ephrin Type-B Receptor 3, Human 1
ERBB4_HUMAN Q15303 CHEMBL3009 Receptor Protein-tyrosine Kinase ErbB-4, Human 1
FAK2_HUMAN Q14289 CHEMBL5469 Protein Tyrosine Kinase 2 Beta, Human 1
FER_HUMAN P16591 CHEMBL3982 Tyrosine-protein Kinase FER, Human 1
FES_HUMAN P07332 CHEMBL5455 Tyrosine-protein Kinase FES, Human 1
FGFR4_HUMAN P22455 CHEMBL3973 Fibroblast Growth Factor Receptor 4, Human 1
IKKE_HUMAN Q14164 CHEMBL3529 Inhibitor Of Nuclear Factor Kappa B Kinase Epsilon Subunit, Human 1
INSRR_HUMAN P14616 CHEMBL5483 Insulin Receptor-related Protein, Human 1
KAPCA_HUMAN P17612 CHEMBL4101 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Human 1
KAPCB_HUMAN P22694 CHEMBL2918 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Human 1
KC1A_HUMAN P48729 CHEMBL2793 Casein Kinase I Alpha, Human 1
KC1G2_HUMAN P78368 CHEMBL2543 Casein Kinase I Gamma 2, Human 1
KC1G3_HUMAN Q9Y6M4 CHEMBL5084 Casein Kinase I Isoform Gamma-3, Human 1
KCC1A_HUMAN Q14012 CHEMBL2493 CaM Kinase I Alpha, Human 1
KCC2A_HUMAN Q9UQM7 CHEMBL4147 CaM Kinase II Alpha, Human 1
KCC2B_HUMAN Q13554 CHEMBL4121 CaM Kinase II Beta, Human 1
KPCA_HUMAN P17252 CHEMBL299 Protein Kinase C Alpha, Human 1
KPCD_HUMAN Q05655 CHEMBL2996 Protein Kinase C Delta, Human 1
KPCE_HUMAN Q02156 CHEMBL3582 Protein Kinase C Epsilon, Human 1
KPCG_HUMAN P05129 CHEMBL2938 Protein Kinase C Gamma, Human 1
KPCI_HUMAN P41743 CHEMBL2598 Protein Kinase C Iota, Human 1
KPCL_HUMAN P24723 CHEMBL3616 Protein Kinase C Eta, Human 1
KPCZ_HUMAN Q05513 CHEMBL3438 Protein Kinase C Zeta, Human 1
LATS1_HUMAN O95835 CHEMBL6167 Serine/threonine-protein Kinase LATS1, Human 1
LATS2_HUMAN Q9NRM7 CHEMBL5907 Serine/threonine-protein Kinase LATS2, Human 1
LCK_MOUSE P06240 CHEMBL2480 Tyrosine-protein Kinase LCK, Mouse 1
LIMK1_HUMAN P53667 CHEMBL3836 LIM Domain Kinase 1, Human 1
LIMK2_HUMAN P53671 CHEMBL5932 LIM Domain Kinase 2, Human 1
M3K10_HUMAN Q02779 CHEMBL2873 Mitogen-activated Protein Kinase Kinase Kinase 10, Human 1
M3K9_HUMAN P80192 CHEMBL2872 Mitogen-activated Protein Kinase Kinase Kinase 9, Human 1
MK04_HUMAN P31152 CHEMBL5759 Mitogen-activated Protein Kinase 4, Human 1
MST4_HUMAN Q9P289 CHEMBL5941 Serine/threonine-protein Kinase MST4, Human 1
MTOR_HUMAN P42345 CHEMBL2842 FK506 Binding Protein 12, Human 1
MUSK_HUMAN O15146 CHEMBL5684 Muscle, Skeletal Receptor Tyrosine Protein Kinase, Human 1
MYLK_CHICK P11799 CHEMBL3062 Myosin Light Chain Kinase, Smooth Muscle, Chick 1
MYO3A_HUMAN Q8NEV4 CHEMBL5546 Myosin IIIA, Human 1
MYO3B_HUMAN Q8WXR4 CHEMBL5654 Myosin-IIIB, Human 1
NEK5_HUMAN Q6P3R8 CHEMBL5044 Serine/threonine-protein Kinase Nek5, Human 1
NTRK1_HUMAN P04629 CHEMBL2815 Nerve Growth Factor Receptor Trk-A, Human 1
NTRK2_HUMAN Q16620 CHEMBL4898 Neurotrophic Tyrosine Kinase Receptor Type 2, Human 1
NTRK3_HUMAN Q16288 CHEMBL5608 NT-3 Growth Factor Receptor, Human 1
PAK3_HUMAN O75914 CHEMBL2999 Serine/threonine-protein Kinase PAK 3, Human 1
PDK1_HUMAN Q15118 CHEMBL4766 Pyruvate Dehydrogenase Kinase Isoform 1, Human 1
PHKG2_HUMAN P15735 CHEMBL2349 Phosphorylase Kinase Gamma Subunit 2, Human 1
PIM1_HUMAN P11309 CHEMBL2147 Serine/threonine-protein Kinase PIM1, Human 1
PIM2_HUMAN Q9P1W9 CHEMBL4523 Serine/threonine-protein Kinase PIM2, Human 1
PIM3_HUMAN Q86V86 CHEMBL5407 Serine/threonine-protein Kinase PIM3, Human 1
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 1
PK3CB_HUMAN P42338 CHEMBL3145 PI3-kinase P110-beta Subunit, Human 1
PK3CD_HUMAN O00329 CHEMBL3130 PI3-kinase P110-delta Subunit, Human 1
PK3CG_HUMAN P48736 CHEMBL3267 PI3-kinase P110-gamma Subunit, Human 1
PKN1_HUMAN Q16512 CHEMBL3384 Protein Kinase N1, Human 1
PLK4_HUMAN O00444 CHEMBL3788 Serine/threonine-protein Kinase PLK4, Human 1
PMYT1_HUMAN Q99640 CHEMBL3984 Tyrosine- And Threonine-specific Cdc2-inhibitory Kinase, Human 1
PYGM_HUMAN P11217 CHEMBL3526 Muscle Glycogen Phosphorylase, Human 1
RIPK1_HUMAN Q13546 CHEMBL5464 Receptor-interacting Serine/threonine-protein Kinase 1, Human 1
ROS1_HUMAN P08922 CHEMBL5568 Proto-oncogene Tyrosine-protein Kinase ROS, Human 1
SRC_CHICK P00523 CHEMBL3655 Tyrosine-protein Kinase SRC, Chick 1
ST17B_HUMAN O94768 CHEMBL3980 Serine/threonine-protein Kinase 17B, Human 1
STK25_HUMAN O00506 CHEMBL5552 Serine/threonine-protein Kinase 25, Human 1
TIE2_HUMAN Q02763 CHEMBL4128 Tyrosine-protein Kinase TIE-2, Human 1
TNK1_HUMAN Q13470 CHEMBL5334 Non-receptor Tyrosine-protein Kinase TNK1, Human 1
TYK2_HUMAN P29597 CHEMBL3553 Tyrosine-protein Kinase TYK2, Human 1
TYRO3_HUMAN Q06418 CHEMBL5314 Tyrosine-protein Kinase Receptor TYRO3, Human 1
VGFR3_HUMAN P35916 CHEMBL1955 Vascular Endothelial Growth Factor Receptor 3, Human 1
WEE1_HUMAN P30291 CHEMBL5491 Serine/threonine-protein Kinase WEE1, Human 1
Z104294 Z104294 CHEMBL1907600 Cyclin-dependent Kinase 5/CDK5 Activator 1 1
Z104295 Z104295 CHEMBL1907601 Cyclin-dependent Kinase 4/cyclin D1 1
Z104296 Z104296 CHEMBL1907602 Cyclin-dependent Kinase 1/cyclin B1 1
Z80951 Z80951 CHEMBL614822 NIH3T3 (Fibroblasts) 1
Z81020 Z81020 CHEMBL395 HepG2 (Hepatoblastoma Cells) 1

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