UCSF

Cyclin A2, Human (650 Compounds)

Swissprot:
CCNA2_HUMAN
Stitch:
CCNA2_HUMAN
UniProt:
P20248
ChEMBL:
CHEMBL2582
Reactome:
REACT_1857
REACT_9029
REACT_169185
REACT_111214
REACT_1915
REACT_1156
REACT_6362
REACT_6837
REACT_9003
REACT_169168
PDB:
1E9H (DOCK)
1FIN (DOCK)
1FVV (DOCK)
1GY3 (DOCK)
1H1P (DOCK)
1H1Q (DOCK)
1H1R (DOCK)
1H1S (DOCK)
1H24 (DOCK)
1H25 (DOCK)
1H26 (DOCK)
1H27 (DOCK)
1H28 (DOCK)
1JST (DOCK)
1JSU (DOCK)
1OGU (DOCK)
1OI9 (DOCK)
1OIU (DOCK)
1OIY (DOCK)
1OKV (DOCK)
1OKW (DOCK)
1OL1 (DOCK)
1OL2 (DOCK)
1P5E (DOCK)
1PKD (DOCK)
1QMZ (DOCK)
1URC (DOCK)
1VYW (DOCK)
2BKZ (DOCK)
2BPM (DOCK)
2C4G (DOCK)
2C5N (DOCK)
2C5O (DOCK)
2C5V (DOCK)
2C5X (DOCK)
2C6T (DOCK)
2CCH (DOCK)
2CCI (DOCK)
2CJM (DOCK)
2I40 (DOCK)
2IW6 (DOCK)
2IW8 (DOCK)
2IW9 (DOCK)
2UUE (DOCK)
2UZB (DOCK)
2UZD (DOCK)
2UZE (DOCK)
2UZL (DOCK)
2V22 (DOCK)
2WEV (DOCK)
2WFY (DOCK)
2WHB (DOCK)
2WIH (DOCK)
2WIP (DOCK)
2WMA (DOCK)
2WMB (DOCK)
2WPA (DOCK)
2WXV (DOCK)
2X1N (DOCK)
3EID (DOCK)
3EJ1 (DOCK)
3EOC (DOCK)
3F5X (DOCK)
CCNA2

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 650 26 6 23
Binding ≤ 1μM 456 17 3 17

Reactome Network (10)

Reactome ID Description Species
REACT_1857 Cyclin A/B1 associated events during G2/M transition Homo sapiens
REACT_9029 Cyclin A:Cdk2-associated events at S phase entry Homo sapiens
REACT_169185 DNA Damage/Telomere Stress Induced Senescence Homo sapiens
REACT_111214 G0 and Early G1 Homo sapiens
REACT_1915 G2 Phase Homo sapiens
REACT_1156 Orc1 removal from chromatin Homo sapiens
REACT_6362 Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 com Homo sapiens
REACT_6837 Regulation of APC/C activators between G1/S and early anaphase Homo sapiens
REACT_9003 SCF(Skp2)-mediated degradation of p27/p21 Homo sapiens
REACT_169168 Senescence-Associated Secretory Phenotype (SASP) Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
CCNA1_HUMAN P78396 CHEMBL3609 Cyclin A1, Human 539
CCNB1_HUMAN P14635 CHEMBL2412 G2/mitotic-specific Cyclin B1, Human 71
CCNB2_HUMAN O95067 CHEMBL3723 G2/mitotic-specific Cyclin B2, Human 70
CCNH_HUMAN P51946 CHEMBL2165 Cyclin H, Human 4
CDK1_HUMAN P06493 CHEMBL308 Cyclin-dependent Kinase 1, Human 73
CDK2_HUMAN P24941 CHEMBL301 Cyclin-dependent Kinase 2, Human 650
CDK7_HUMAN P50613 CHEMBL3055 Cyclin-dependent Kinase 7, Human 5
MAT1_HUMAN P51948 CHEMBL5053 CDK-activating Kinase Assembly Factor MAT1, Human 2
PLK1_HUMAN P53350 CHEMBL3024 Serine/threonine-protein Kinase PLK1, Human 47
WEE1_HUMAN P30291 CHEMBL5491 Serine/threonine-protein Kinase WEE1, Human 1

Cyclin A:Cdk2-associated events at S phase entry

Uniprot Swissprot Chembl Description Number Shared
CCNA1_HUMAN P78396 CHEMBL3609 Cyclin A1, Human 539
CCNH_HUMAN P51946 CHEMBL2165 Cyclin H, Human 4
CDK2_HUMAN P24941 CHEMBL301 Cyclin-dependent Kinase 2, Human 650
CDK7_HUMAN P50613 CHEMBL3055 Cyclin-dependent Kinase 7, Human 5
MAT1_HUMAN P51948 CHEMBL5053 CDK-activating Kinase Assembly Factor MAT1, Human 2
WEE1_HUMAN P30291 CHEMBL5491 Serine/threonine-protein Kinase WEE1, Human 1

DNA Damage/Telomere Stress Induced Senescence

Uniprot Swissprot Chembl Description Number Shared
CCNA1_HUMAN P78396 CHEMBL3609 Cyclin A1, Human 539
CCNE1_HUMAN P24864 CHEMBL3617 G1/S-specific Cyclin E1, Human 111
CCNE2_HUMAN O96020 CHEMBL2884 G1/S-specific Cyclin E2, Human 110
CDK2_HUMAN P24941 CHEMBL301 Cyclin-dependent Kinase 2, Human 650

G0 and Early G1

Uniprot Swissprot Chembl Description Number Shared
CCNA1_HUMAN P78396 CHEMBL3609 Cyclin A1, Human 539
CCNE1_HUMAN P24864 CHEMBL3617 G1/S-specific Cyclin E1, Human 111
CCNE2_HUMAN O96020 CHEMBL2884 G1/S-specific Cyclin E2, Human 110
CDK1_HUMAN P06493 CHEMBL308 Cyclin-dependent Kinase 1, Human 73
CDK2_HUMAN P24941 CHEMBL301 Cyclin-dependent Kinase 2, Human 650
DYR1A_HUMAN Q13627 CHEMBL2292 Dual-specificity Tyrosine-phosphorylation Regulated Kinase 1A, Human 3

G2 Phase

Uniprot Swissprot Chembl Description Number Shared
CCNA1_HUMAN P78396 CHEMBL3609 Cyclin A1, Human 539
CDK2_HUMAN P24941 CHEMBL301 Cyclin-dependent Kinase 2, Human 650

Orc1 removal from chromatin

Uniprot Swissprot Chembl Description Number Shared
CCNA1_HUMAN P78396 CHEMBL3609 Cyclin A1, Human 539
CDK2_HUMAN P24941 CHEMBL301 Cyclin-dependent Kinase 2, Human 650

Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 com

Uniprot Swissprot Chembl Description Number Shared
CCNA1_HUMAN P78396 CHEMBL3609 Cyclin A1, Human 539
CDK1_HUMAN P06493 CHEMBL308 Cyclin-dependent Kinase 1, Human 73

Regulation of APC/C activators between G1/S and early anaphase

Uniprot Swissprot Chembl Description Number Shared
CCNA1_HUMAN P78396 CHEMBL3609 Cyclin A1, Human 539
CCNB1_HUMAN P14635 CHEMBL2412 G2/mitotic-specific Cyclin B1, Human 71
CDK1_HUMAN P06493 CHEMBL308 Cyclin-dependent Kinase 1, Human 73
CDK2_HUMAN P24941 CHEMBL301 Cyclin-dependent Kinase 2, Human 650

SCF(Skp2)-mediated degradation of p27/p21

Uniprot Swissprot Chembl Description Number Shared
CCNA1_HUMAN P78396 CHEMBL3609 Cyclin A1, Human 539
CCNE1_HUMAN P24864 CHEMBL3617 G1/S-specific Cyclin E1, Human 111
CCNE2_HUMAN O96020 CHEMBL2884 G1/S-specific Cyclin E2, Human 110
CDK2_HUMAN P24941 CHEMBL301 Cyclin-dependent Kinase 2, Human 650

Senescence-Associated Secretory Phenotype (SASP)

Uniprot Swissprot Chembl Description Number Shared
CCNA1_HUMAN P78396 CHEMBL3609 Cyclin A1, Human 539
CDK2_HUMAN P24941 CHEMBL301 Cyclin-dependent Kinase 2, Human 650
CDK4_HUMAN P11802 CHEMBL331 Cyclin-dependent Kinase 4, Human 47
CDK6_HUMAN Q00534 CHEMBL2508 Cyclin-dependent Kinase 6, Human 5
KS6A1_HUMAN Q15418 CHEMBL2553 Ribosomal Protein S6 Kinase Alpha 1, Human 2
KS6A2_HUMAN Q15349 CHEMBL3906 Ribosomal Protein S6 Kinase Alpha 2, Human 3
KS6A3_HUMAN P51812 CHEMBL2345 Ribosomal Protein S6 Kinase Alpha 3, Human 3
MK01_HUMAN P28482 CHEMBL4040 MAP Kinase ERK2, Human 4
MK03_HUMAN P27361 CHEMBL3385 MAP Kinase ERK1, Human 2
MK07_HUMAN Q13164 CHEMBL5332 Mitogen-activated Protein Kinase 7, Human 2
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
CCNA1_HUMAN P78396 CHEMBL3609 Cyclin A1, Human 597 21 4 15

Clustered By Gene (0)

Clustered By Organism (2)

Code Description Substances Purchasable Natural In Man
CCNA2-1-E Cyclin A2 (cluster #1 Of 3), Eukaryotic 616 24 6 17
CCNA2-2-E Cyclin A2 (cluster #2 Of 3), Eukaryotic 22 0 0 0
CCNA2-3-E Cyclin A2 (cluster #3 Of 3), Eukaryotic 26 2 0 6
Uniprot Swissprot Chembl Description Number Shared
CDK2_HUMAN P24941 CHEMBL301 Cyclin-dependent Kinase 2, Human 650
CCNA1_HUMAN P78396 CHEMBL3609 Cyclin A1, Human 539
CCNE1_HUMAN P24864 CHEMBL3617 G1/S-specific Cyclin E1, Human 111
CCNE2_HUMAN O96020 CHEMBL2884 G1/S-specific Cyclin E2, Human 110
CHK1_HUMAN O14757 CHEMBL4630 Serine/threonine-protein Kinase Chk1, Human 80
CDK1_HUMAN P06493 CHEMBL308 Cyclin-dependent Kinase 1, Human 73
CCNB1_HUMAN P14635 CHEMBL2412 G2/mitotic-specific Cyclin B1, Human 71
CCNB2_HUMAN O95067 CHEMBL3723 G2/mitotic-specific Cyclin B2, Human 70
CCNB3_HUMAN Q8WWL7 CHEMBL3606 G2/mitotic-specific Cyclin B3, Human 69
CDK4_HUMAN P11802 CHEMBL331 Cyclin-dependent Kinase 4, Human 47
PLK1_HUMAN P53350 CHEMBL3024 Serine/threonine-protein Kinase PLK1, Human 47
CCND2_HUMAN P30279 CHEMBL3613 G1/S-specific Cyclin D2, Human 38
AURKA_HUMAN O14965 CHEMBL4722 Serine/threonine-protein Kinase Aurora-A, Human 37
Z104294 Z104294 CHEMBL1907600 Cyclin-dependent Kinase 5/CDK5 Activator 1 36
Z104295 Z104295 CHEMBL1907601 Cyclin-dependent Kinase 4/cyclin D1 36
CCND3_HUMAN P30281 CHEMBL2422 G1/S-specific Cyclin D3, Human 33
CCND1_HUMAN P24385 CHEMBL3610 G1/S-specific Cyclin D1, Human 30
GSK3B_HUMAN P49841 CHEMBL262 Glycogen Synthase Kinase-3 Beta, Human 30
Z104296 Z104296 CHEMBL1907602 Cyclin-dependent Kinase 1/cyclin B1 29
PLK3_HUMAN Q9H4B4 CHEMBL4897 Serine/threonine-protein Kinase PLK3, Human 24
PLK2_HUMAN Q9NYY3 CHEMBL5938 Serine/threonine-protein Kinase PLK2, Human 23
CDK9_HUMAN P50750 CHEMBL3116 Cyclin-dependent Kinase 9, Human 22
CCNT1_HUMAN O60563 CHEMBL2108 Cyclin T1, Human 21
DYR1A_RAT Q63470 CHEMBL5508 Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1A, Rat 13
FGFR2_HUMAN P21802 CHEMBL4142 Fibroblast Growth Factor Receptor 2, Human 12
FGFR1_HUMAN P11362 CHEMBL3650 Fibroblast Growth Factor Receptor 1, Human 11
GSK3A_HUMAN P49840 CHEMBL2850 Glycogen Synthase Kinase-3 Alpha, Human 11
CDK5_HUMAN Q00535 CHEMBL4036 Cyclin-dependent Kinase 5, Human 10
FGFR3_HUMAN P22607 CHEMBL2742 Fibroblast Growth Factor Receptor 3, Human 10
TTK_HUMAN P33981 CHEMBL3983 Dual Specificity Protein Kinase TTK, Human 10
FGFR4_HUMAN P22455 CHEMBL3973 Fibroblast Growth Factor Receptor 4, Human 9
VGFR2_HUMAN P35968 CHEMBL279 Vascular Endothelial Growth Factor Receptor 2, Human 8
PGFRB_HUMAN P09619 CHEMBL1913 Platelet-derived Growth Factor Receptor Beta, Human 7
CDK6_HUMAN Q00534 CHEMBL2508 Cyclin-dependent Kinase 6, Human 5
CDK7_HUMAN P50613 CHEMBL3055 Cyclin-dependent Kinase 7, Human 5
GSK3B_RAT P18266 CHEMBL3669 Glycogen Synthase Kinase-3 Beta, Rat 5
KAPCA_HUMAN P17612 CHEMBL4101 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Human 5
KAPCB_HUMAN P22694 CHEMBL2918 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Human 5
KAPCG_HUMAN P22612 CHEMBL2743 CAMP-dependent Protein Kinase, Gamma Catalytic Subunit, Human 5
KC1E_HUMAN P49674 CHEMBL4937 Casein Kinase I Epsilon, Human 5
KC1G1_HUMAN Q9HCP0 CHEMBL2426 Casein Kinase I Gamma 1, Human 5
KC1G2_HUMAN P78368 CHEMBL2543 Casein Kinase I Gamma 2, Human 5
KPCB_HUMAN P05771 CHEMBL3045 Protein Kinase C Beta, Human 5
MK10_HUMAN P53779 CHEMBL2637 C-Jun N-terminal Kinase 3, Human 5
NTRK1_HUMAN P04629 CHEMBL2815 Nerve Growth Factor Receptor Trk-A, Human 5
CCNH_HUMAN P51946 CHEMBL2165 Cyclin H, Human 4
E2AK2_HUMAN P19525 CHEMBL5785 Interferon-induced, Double-stranded RNA-activated Protein Kinase, Human 4
FLT3_HUMAN P36888 CHEMBL1974 Tyrosine-protein Kinase Receptor FLT3, Human 4
INSR_HUMAN P06213 CHEMBL1981 Insulin Receptor, Human 4
KC1D_HUMAN P48730 CHEMBL2828 Casein Kinase I Delta, Human 4
KIT_HUMAN P10721 CHEMBL1936 Stem Cell Growth Factor Receptor, Human 4
KPCD_HUMAN Q05655 CHEMBL2996 Protein Kinase C Delta, Human 4
MK01_HUMAN P28482 CHEMBL4040 MAP Kinase ERK2, Human 4
MK08_HUMAN P45983 CHEMBL2276 C-Jun N-terminal Kinase 1, Human 4
PLK4_HUMAN O00444 CHEMBL3788 Serine/threonine-protein Kinase PLK4, Human 4
VGFR2_MOUSE P35918 CHEMBL3337 Vascular Endothelial Growth Factor Receptor 2, Mouse 4
VGFR3_HUMAN P35916 CHEMBL1955 Vascular Endothelial Growth Factor Receptor 3, Human 4
ABL1_HUMAN P00519 CHEMBL1862 Tyrosine-protein Kinase ABL, Human 3
ALK_HUMAN Q9UM73 CHEMBL4247 ALK Tyrosine Kinase Receptor, Human 3
CCNB_MARGL P15206 CHEMBL4260 G2/mitotic-specific Cyclin B, Margl 3
CDK16_HUMAN Q00536 CHEMBL4597 Serine/threonine-protein Kinase PCTAIRE-1, Human 3
CDK1_YEAST P00546 CHEMBL5213 Cell Division Control Protein 28, Yeast 3
CLK1_HUMAN P49759 CHEMBL4224 Dual Specificty Protein Kinase CLK1, Human 3
CLK2_HUMAN P49760 CHEMBL4225 Dual Specificity Protein Kinase CLK2, Human 3
DYR1A_HUMAN Q13627 CHEMBL2292 Dual-specificity Tyrosine-phosphorylation Regulated Kinase 1A, Human 3
FAK1_HUMAN Q05397 CHEMBL2695 Focal Adhesion Kinase 1, Human 3
KC1A_HUMAN P48729 CHEMBL2793 Casein Kinase I Alpha, Human 3
KPCA_HUMAN P17252 CHEMBL299 Protein Kinase C Alpha, Human 3
KPCE_HUMAN Q02156 CHEMBL3582 Protein Kinase C Epsilon, Human 3
KPCL_HUMAN P24723 CHEMBL3616 Protein Kinase C Eta, Human 3
KPCT_HUMAN Q04759 CHEMBL3920 Protein Kinase C Theta, Human 3
KPCZ_HUMAN Q05513 CHEMBL3438 Protein Kinase C Zeta, Human 3
KS6A2_HUMAN Q15349 CHEMBL3906 Ribosomal Protein S6 Kinase Alpha 2, Human 3
KS6A3_HUMAN P51812 CHEMBL2345 Ribosomal Protein S6 Kinase Alpha 3, Human 3
MK09_HUMAN P45984 CHEMBL4179 C-Jun N-terminal Kinase 2, Human 3
PAK4_HUMAN O96013 CHEMBL4482 Serine/threonine-protein Kinase PAK 4, Human 3
PDPK1_HUMAN O15530 CHEMBL2534 3-phosphoinositide Dependent Protein Kinase-1, Human 3
PGFRA_HUMAN P16234 CHEMBL2007 Platelet-derived Growth Factor Receptor Alpha, Human 3
SRC_HUMAN P12931 CHEMBL267 Tyrosine-protein Kinase SRC, Human 3
UFO_HUMAN P30530 CHEMBL4895 Tyrosine-protein Kinase Receptor UFO, Human 3
VGFR1_HUMAN P17948 CHEMBL1868 Vascular Endothelial Growth Factor Receptor 1, Human 3
Z104300 Z104300 CHEMBL1907606 Mitogen-activated Protein Kinase; ERK1/ERK2 3
AAK1_HUMAN Q2M2I8 CHEMBL3830 Adaptor-associated Kinase, Human 2
AAPK1_HUMAN Q13131 CHEMBL4045 AMP-activated Protein Kinase, Alpha-1 Subunit, Human 2
ACVR1_HUMAN Q04771 CHEMBL5903 Activin Receptor Type-1, Human 2
AURKB_HUMAN Q96GD4 CHEMBL2185 Serine/threonine-protein Kinase Aurora-B, Human 2
AVR2B_HUMAN Q13705 CHEMBL5466 Activin Receptor Type-2B, Human 2
CCNT2_HUMAN O60583 CHEMBL1293321 Cyclin-T2, Human 2
CDC7_HUMAN O00311 CHEMBL5443 Cell Division Cycle 7-related Protein Kinase, Human 2
CDK14_HUMAN O94921 CHEMBL6162 Serine/threonine-protein Kinase PFTAIRE-1, Human 2
CDK17_HUMAN Q00537 CHEMBL5790 Serine/threonine-protein Kinase PCTAIRE-2, Human 2
CDK18_HUMAN Q07002 CHEMBL5316 Serine/threonine-protein Kinase PCTAIRE-3, Human 2
CDK3_HUMAN Q00526 CHEMBL4442 Cyclin-dependent Kinase 3, Human 2
CLK3_HUMAN P49761 CHEMBL4226 Dual Specificity Protein Kinase CLK3, Human 2
CLK4_HUMAN Q9HAZ1 CHEMBL4203 Dual Specificity Protein Kinase CLK4, Human 2
CSF1R_HUMAN P07333 CHEMBL1844 Macrophage Colony Stimulating Factor Receptor, Human 2
CSK22_HUMAN P19784 CHEMBL4070 Casein Kinase II Alpha (prime), Human 2
DCLK1_HUMAN O15075 CHEMBL5683 Serine/threonine-protein Kinase DCLK1, Human 2
DCLK3_HUMAN Q9C098 CHEMBL6123 Serine/threonine-protein Kinase DCLK3, Human 2
DMPK_HUMAN Q09013 CHEMBL5320 Myotonin-protein Kinase, Human 2
DYR1B_HUMAN Q9Y463 CHEMBL5543 Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1B, Human 2
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 2
FGFR1_MOUSE P16092 CHEMBL3960 Fibroblast Growth Factor Receptor 1, Mouse 2
GAK_HUMAN O14976 CHEMBL4355 Serine/threonine-protein Kinase GAK, Human 2
IKKB_HUMAN O14920 CHEMBL1991 Inhibitor Of Nuclear Factor Kappa B Kinase Beta Subunit, Human 2
IKKE_HUMAN Q14164 CHEMBL3529 Inhibitor Of Nuclear Factor Kappa B Kinase Epsilon Subunit, Human 2
JAK1_HUMAN P23458 CHEMBL2835 Tyrosine-protein Kinase JAK1, Human 2
JAK2_HUMAN O60674 CHEMBL2971 Tyrosine-protein Kinase JAK2, Human 2
JAK3_HUMAN P52333 CHEMBL2148 Tyrosine-protein Kinase JAK3, Human 2
KC1G3_HUMAN Q9Y6M4 CHEMBL5084 Casein Kinase I Isoform Gamma-3, Human 2
KCC2A_HUMAN Q9UQM7 CHEMBL4147 CaM Kinase II Alpha, Human 2
KCC2B_HUMAN Q13554 CHEMBL4121 CaM Kinase II Beta, Human 2
KKCC1_HUMAN Q8N5S9 CHEMBL5256 CaM-kinase Kinase Alpha, Human 2
KKCC2_HUMAN Q96RR4 CHEMBL5284 CaM-kinase Kinase Beta, Human 2
KPCD1_HUMAN Q15139 CHEMBL3863 Protein Kinase C Mu, Human 2
KPCD3_HUMAN O94806 CHEMBL2595 Protein Kinase C Nu, Human 2
KPCG_HUMAN P05129 CHEMBL2938 Protein Kinase C Gamma, Human 2
KS6A1_HUMAN Q15418 CHEMBL2553 Ribosomal Protein S6 Kinase Alpha 1, Human 2
KS6A4_HUMAN O75676 CHEMBL3125 Ribosomal Protein S6 Kinase Alpha 4, Human 2
KS6A5_HUMAN O75582 CHEMBL4237 Ribosomal Protein S6 Kinase Alpha 5, Human 2
LCK_HUMAN P06239 CHEMBL258 Tyrosine-protein Kinase LCK, Human 2
M3K9_HUMAN P80192 CHEMBL2872 Mitogen-activated Protein Kinase Kinase Kinase 9, Human 2
M4K1_HUMAN Q92918 CHEMBL5749 Mitogen-activated Protein Kinase Kinase Kinase Kinase 1, Human 2
M4K3_HUMAN Q8IVH8 CHEMBL5432 Mitogen-activated Protein Kinase Kinase Kinase Kinase 3, Human 2
MAT1_HUMAN P51948 CHEMBL5053 CDK-activating Kinase Assembly Factor MAT1, Human 2
MERTK_HUMAN Q12866 CHEMBL5331 Proto-oncogene Tyrosine-protein Kinase MER, Human 2
MK03_HUMAN P27361 CHEMBL3385 MAP Kinase ERK1, Human 2
MK07_HUMAN Q13164 CHEMBL5332 Mitogen-activated Protein Kinase 7, Human 2
MK15_HUMAN Q8TD08 CHEMBL5198 Mitogen-activated Protein Kinase 15, Human 2
MP2K1_HUMAN Q02750 CHEMBL3587 Dual Specificity Mitogen-activated Protein Kinase Kinase 1, Human 2
MP2K6_HUMAN P52564 CHEMBL2171 Dual Specificity Mitogen-activated Protein Kinase Kinase 6, Human 2
NUAK2_HUMAN Q9H093 CHEMBL5698 NUAK Family SNF1-like Kinase 2, Human 2
PDK1_HUMAN Q15118 CHEMBL4766 Pyruvate Dehydrogenase Kinase Isoform 1, Human 2
PGFRA_RAT P20786 CHEMBL2513 Platelet-derived Growth Factor Receptor Alpha, Rat 2
PHKG1_HUMAN Q16816 CHEMBL4004 Phosphorylase Kinase Gamma Subunit 1, Human 2
PHKG2_HUMAN P15735 CHEMBL2349 Phosphorylase Kinase Gamma Subunit 2, Human 2
PIM1_HUMAN P11309 CHEMBL2147 Serine/threonine-protein Kinase PIM1, Human 2
PIM3_HUMAN Q86V86 CHEMBL5407 Serine/threonine-protein Kinase PIM3, Human 2
Q17066_ASTPE Q17066 CHEMBL5124 Cdc2, Astpe 2
Q95J97_RABIT Q95J97 CHEMBL4885 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Rabit 2
ROCK2_HUMAN O75116 CHEMBL2973 Rho-associated Protein Kinase 2, Human 2
SGK1_HUMAN O00141 CHEMBL2343 Serine/threonine-protein Kinase Sgk1, Human 2
STK3_HUMAN Q13188 CHEMBL4708 Serine/threonine-protein Kinase MST2, Human 2
TIE2_HUMAN Q02763 CHEMBL4128 Tyrosine-protein Kinase TIE-2, Human 2
TNI3K_HUMAN Q59H18 CHEMBL5260 Serine/threonine-protein Kinase TNNI3K, Human 2
Z104299 Z104299 CHEMBL1907605 Cyclin-dependent Kinase 2/cyclin E1 2
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 1
5HT2B_HUMAN P41595 CHEMBL1833 Serotonin 2b (5-HT2b) Receptor, Human 1
AAPK2_HUMAN P54646 CHEMBL2116 AMP-activated Protein Kinase, Alpha-2 Subunit, Human 1
ACVL1_HUMAN P37023 CHEMBL5311 Serine/threonine-protein Kinase Receptor R3, Human 1
ADCK3_HUMAN Q8NI60 CHEMBL5550 Chaperone Activity Of Bc1 Complex-like, Mitochondrial, Human 1
ANKK1_HUMAN Q8NFD2 CHEMBL5547 Ankyrin Repeat And Protein Kinase Domain-containing Protein 1, Human 1
AURKC_HUMAN Q9UQB9 CHEMBL3935 Serine/threonine-protein Kinase Aurora-C, Human 1
AVR2A_HUMAN P27037 CHEMBL5616 Activin Receptor Type-2A, Human 1
BLK_HUMAN P51451 CHEMBL2250 Tyrosine-protein Kinase BLK, Human 1
BMP2K_HUMAN Q9NSY1 CHEMBL4522 BMP-2-inducible Protein Kinase, Human 1
BMPR2_HUMAN Q13873 CHEMBL5467 Bone Morphogenetic Protein Receptor Type-2, Human 1
BMX_HUMAN P51813 CHEMBL3834 Tyrosine-protein Kinase BMX, Human 1
BRSK1_HUMAN Q8TDC3 CHEMBL5650 BR Serine/threonine-protein Kinase 1, Human 1
BRSK2_HUMAN Q8IWQ3 CHEMBL4574 BR Serine/threonine-protein Kinase 2, Human 1
CD11A_HUMAN Q9UQ88 CHEMBL5416 PITSLRE Serine/threonine-protein Kinase CDC2L2, Human 1
CD11B_HUMAN P21127 CHEMBL5808 PITSLRE Serine/threonine-protein Kinase CDC2L1, Human 1
CD5R1_HUMAN Q15078 CHEMBL2783 Cyclin-dependent Kinase 5 Regulatory Subunit 1, Human 1
CDK19_HUMAN Q9BWU1 CHEMBL6002 Cell Division Cycle 2-like Protein Kinase 6, Human 1
CDK8_HUMAN P49336 CHEMBL5719 Cell Division Protein Kinase 8, Human 1
CFTR_HUMAN P13569 CHEMBL4051 Cystic Fibrosis Transmembrane Conductance Regulator, Human 1
CSK21_HUMAN P68400 CHEMBL3629 Casein Kinase II Alpha, Human 1
CSK2B_HUMAN P67870 CHEMBL2358 Casein Kinase II Beta, Human 1
CTRO_HUMAN O14578 CHEMBL5579 Citron Rho-interacting Kinase, Human 1
DAPK3_HUMAN O43293 CHEMBL2468 Death-associated Protein Kinase 3, Human 1
DCLK2_HUMAN Q8N568 CHEMBL5519 Serine/threonine-protein Kinase DCLK2, Human 1
DYR1A_MOUSE Q61214 CHEMBL4750 Dual-specificity Tyrosine-phosphorylation Regulated Kinase 1A, Mouse 1
DYRK2_HUMAN Q92630 CHEMBL4376 Dual-specificity Tyrosine-phosphorylation Regulated Kinase 2, Human 1
E2AK4_HUMAN Q9P2K8 CHEMBL5358 Eukaryotic Translation Initiation Factor 2-alpha Kinase 4, Human 1
EPHA2_HUMAN P29317 CHEMBL2068 Ephrin Type-A Receptor 2, Human 1
EPHA3_HUMAN P29320 CHEMBL4954 Ephrin Type-A Receptor 3, Human 1
EPHA5_HUMAN P54756 CHEMBL3987 Ephrin Type-A Receptor 5, Human 1
EPHA7_HUMAN Q15375 CHEMBL4602 Ephrin Type-A Receptor 7, Human 1
EPHB1_HUMAN P54762 CHEMBL5072 Ephrin Type-B Receptor 1, Human 1
EPHB4_HUMAN P54760 CHEMBL5147 Ephrin Type-B Receptor 4, Human 1
FGR_HUMAN P09769 CHEMBL4454 Tyrosine-protein Kinase FGR, Human 1
FYN_HUMAN P06241 CHEMBL1841 Tyrosine-protein Kinase FYN, Human 1
IGF1R_HUMAN P08069 CHEMBL1957 Insulin-like Growth Factor I Receptor, Human 1
IRAK3_HUMAN Q9Y616 CHEMBL5081 Interleukin-1 Receptor-associated Kinase 3, Human 1
ITK_HUMAN Q08881 CHEMBL2959 Tyrosine-protein Kinase ITK/TSK, Human 1
KAP2_BOVIN P00515 CHEMBL3654 CAMP-dependent Protein Kinase Type II-alpha Regulatory Subunit, Bovin 1
KCC2D_HUMAN Q13557 CHEMBL2801 CaM Kinase II Delta, Human 1
KCC2G_HUMAN Q13555 CHEMBL3829 CaM Kinase II Gamma, Human 1
KCC4_HUMAN Q16566 CHEMBL2494 CaM Kinase IV, Human 1
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 1
KGP1_HUMAN Q13976 CHEMBL4273 CGMP-dependent Protein Kinase 1 Beta, Human 1
KGP2_HUMAN Q13237 CHEMBL2896 CGMP-dependent Protein Kinase 2, Human 1
KPBB_HUMAN Q93100 CHEMBL3844 Phosphorylase Kinase Beta Subunit, Human 1
KPCD2_HUMAN Q9BZL6 CHEMBL4900 Serine/threonine-protein Kinase D2, Human 1
KPCI_HUMAN P41743 CHEMBL2598 Protein Kinase C Iota, Human 1
KS6A6_HUMAN Q9UK32 CHEMBL4924 Ribosomal Protein S6 Kinase Alpha 6, Human 1
KSYK_HUMAN P43405 CHEMBL2599 Tyrosine-protein Kinase SYK, Human 1
LIMK1_HUMAN P53667 CHEMBL3836 LIM Domain Kinase 1, Human 1
LIMK2_HUMAN P53671 CHEMBL5932 LIM Domain Kinase 2, Human 1
LTK_HUMAN P29376 CHEMBL5627 Leukocyte Tyrosine Kinase Receptor, Human 1
LYN_HUMAN P07948 CHEMBL3905 Tyrosine-protein Kinase Lyn, Human 1
M3K10_HUMAN Q02779 CHEMBL2873 Mitogen-activated Protein Kinase Kinase Kinase 10, Human 1
M4K5_HUMAN Q9Y4K4 CHEMBL4852 Mitogen-activated Protein Kinase Kinase Kinase Kinase 5, Human 1
MARK1_HUMAN Q9P0L2 CHEMBL5940 Serine/threonine-protein Kinase MARK1, Human 1
MARK2_HUMAN Q7KZI7 CHEMBL3831 MAP/microtubule Affinity-regulating Kinase 2, Human 1
MARK3_HUMAN P27448 CHEMBL5600 Serine/threonine-protein Kinase C-TAK1, Human 1
MARK4_HUMAN Q96L34 CHEMBL5754 MAP/microtubule Affinity-regulating Kinase 4, Human 1
MET_HUMAN P08581 CHEMBL3717 Hepatocyte Growth Factor Receptor, Human 1
MK04_HUMAN P31152 CHEMBL5759 Mitogen-activated Protein Kinase 4, Human 1
MK06_HUMAN Q16659 CHEMBL5121 Mitogen-activated Protein Kinase 6, Human 1
MK10_RAT P49187 CHEMBL4092 C-Jun N-terminal Kinase 3, Rat 1
MK14_HUMAN Q16539 CHEMBL260 MAP Kinase P38 Alpha, Human 1
MKNK2_HUMAN Q9HBH9 CHEMBL4204 MAP Kinase Signal-integrating Kinase 2, Human 1
MP2K2_HUMAN P36507 CHEMBL2964 Dual Specificity Mitogen-activated Protein Kinase Kinase 2, Human 1
MP2K3_HUMAN P46734 CHEMBL2109 Dual Specificity Mitogen-activated Protein Kinase Kinase 3, Human 1
MP2K4_HUMAN P45985 CHEMBL2897 Dual Specificity Mitogen-activated Protein Kinase Kinase 4, Human 1
MRCKA_HUMAN Q5VT25 CHEMBL4516 Serine/threonine-protein Kinase MRCK-A, Human 1
MRCKB_HUMAN Q9Y5S2 CHEMBL5052 Serine/threonine-protein Kinase MRCK Beta, Human 1
MST4_HUMAN Q9P289 CHEMBL5941 Serine/threonine-protein Kinase MST4, Human 1
MYLK_HUMAN Q15746 CHEMBL2428 Myosin Light Chain Kinase, Smooth Muscle, Human 1
NEK2_HUMAN P51955 CHEMBL3835 Serine/threonine-protein Kinase NEK2, Human 1
NUAK1_HUMAN O60285 CHEMBL5784 NUAK Family SNF1-like Kinase 1, Human 1
P90584_PLAFA P90584 CHEMBL4090 Protein Kinase Pfmrk, Plafa 1
PAK3_HUMAN O75914 CHEMBL2999 Serine/threonine-protein Kinase PAK 3, Human 1
PAK6_HUMAN Q9NQU5 CHEMBL4311 Serine/threonine-protein Kinase PAK6, Human 1
PAK7_HUMAN Q9P286 CHEMBL4524 Serine/threonine-protein Kinase PAK7, Human 1
PI42B_HUMAN P78356 CHEMBL5667 Phosphatidylinositol-5-phosphate 4-kinase Type-2 Beta, Human 1
PI51A_HUMAN Q99755 CHEMBL5969 Phosphatidylinositol-4-phosphate 5-kinase Type-1 Alpha, Human 1
PIM2_HUMAN Q9P1W9 CHEMBL4523 Serine/threonine-protein Kinase PIM2, Human 1
PKN1_HUMAN Q16512 CHEMBL3384 Protein Kinase N1, Human 1
PKN2_HUMAN Q16513 CHEMBL3032 Protein Kinase N2, Human 1
PYGM_HUMAN P11217 CHEMBL3526 Muscle Glycogen Phosphorylase, Human 1
Q8MMZ8_EIMTE Q8MMZ8 CHEMBL5036 CGMP-dependent Protein Kinase, Eimte 1
RAF1_HUMAN P04049 CHEMBL1906 Serine/threonine-protein Kinase RAF, Human 1
RET_HUMAN P07949 CHEMBL2041 Tyrosine-protein Kinase Receptor RET, Human 1
RIOK1_HUMAN Q9BRS2 CHEMBL5975 Serine/threonine-protein Kinase RIO1, Human 1
RIOK3_HUMAN O14730 CHEMBL5659 Serine/threonine-protein Kinase RIO3, Human 1
RIPK1_HUMAN Q13546 CHEMBL5464 Receptor-interacting Serine/threonine-protein Kinase 1, Human 1
SC6A3_HUMAN Q01959 CHEMBL238 Dopamine Transporter, Human 1
SIK1_HUMAN P57059 CHEMBL6082 Serine/threonine-protein Kinase SIK1, Human 1
SIK2_HUMAN Q9H0K1 CHEMBL5699 Serine/threonine-protein Kinase SIK2, Human 1
SLK_HUMAN Q9H2G2 CHEMBL4202 Serine/threonine-protein Kinase 2, Human 1
SRMS_HUMAN Q9H3Y6 CHEMBL5703 Tyrosine-protein Kinase Srms, Human 1
SRPK1_HUMAN Q96SB4 CHEMBL4375 Serine/threonine-protein Kinase SRPK1, Human 1
ST17A_HUMAN Q9UEE5 CHEMBL4525 Serine/threonine-protein Kinase 17A, Human 1
ST17B_HUMAN O94768 CHEMBL3980 Serine/threonine-protein Kinase 17B, Human 1
STK10_HUMAN O94804 CHEMBL3981 Serine/threonine-protein Kinase 10, Human 1
STK16_HUMAN O75716 CHEMBL3938 Serine/threonine-protein Kinase 16, Human 1
STK24_HUMAN Q9Y6E0 CHEMBL5082 Serine/threonine-protein Kinase 24, Human 1
STK25_HUMAN O00506 CHEMBL5552 Serine/threonine-protein Kinase 25, Human 1
STK33_HUMAN Q9BYT3 CHEMBL6005 Serine/threonine-protein Kinase 33, Human 1
STK4_HUMAN Q13043 CHEMBL4598 Serine/threonine-protein Kinase MST1, Human 1
TAOK1_HUMAN Q7L7X3 CHEMBL5261 Serine/threonine-protein Kinase TAO1, Human 1
TEC_HUMAN P42680 CHEMBL4246 Tyrosine-protein Kinase TEC, Human 1
TESK1_HUMAN Q15569 CHEMBL5604 Dual Specificity Testis-specific Protein Kinase 1, Human 1
TGFR2_HUMAN P37173 CHEMBL4267 TGF-beta Receptor Type II, Human 1
TIE1_HUMAN P35590 CHEMBL5274 Tyrosine-protein Kinase Receptor Tie-1, Human 1
TLK1_HUMAN Q9UKI8 CHEMBL5388 Serine/threonine-protein Kinase Tousled-like 1, Human 1
TLK2_HUMAN Q86UE8 CHEMBL5404 Serine/threonine-protein Kinase Tousled-like 2, Human 1
TYK2_HUMAN P29597 CHEMBL3553 Tyrosine-protein Kinase TYK2, Human 1
WEE1_HUMAN P30291 CHEMBL5491 Serine/threonine-protein Kinase WEE1, Human 1

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