UCSF

Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1A, Rat (98 Compounds)

Swissprot:
DYR1A_RAT
Stitch:
DYR1A_RAT
UniProt:
Q63470
ChEMBL:
CHEMBL5508
Reactome:
REACT_199174
PDB:
Dyrk1a

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 98 1 2 2
Binding ≤ 1μM 62 1 2 2

Reactome Network (1)

Reactome ID Description Species
REACT_199174 G0 and Early G1 Rattus norvegicus
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
DYR1A_HUMAN Q13627 CHEMBL2292 Dual-specificity Tyrosine-phosphorylation Regulated Kinase 1A, Human 65 11 2 7
DYR1A_MOUSE Q61214 CHEMBL4750 Dual-specificity Tyrosine-phosphorylation Regulated Kinase 1A, Mouse 7 5 0 1

Clustered By Gene (0)

Clustered By Organism (2)

Code Description Substances Purchasable Natural In Man
DYR1A-1-E Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1A (cluster #1 Of 3), Eukaryotic 99 6 3 4
DYR1A-2-E Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1A (cluster #2 Of 3), Eukaryotic 2 2 0 2
DYR1A-3-E Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1A (cluster #3 Of 3), Eukaryotic 67 7 1 3
Uniprot Swissprot Chembl Description Number Shared
Z104294 Z104294 CHEMBL1907600 Cyclin-dependent Kinase 5/CDK5 Activator 1 56
CLK1_MOUSE P22518 CHEMBL1075280 Dual Specificity Protein Kinase CLK1, Mouse 35
DYRK2_HUMAN Q92630 CHEMBL4376 Dual-specificity Tyrosine-phosphorylation Regulated Kinase 2, Human 35
CLK1_HUMAN P49759 CHEMBL4224 Dual Specificty Protein Kinase CLK1, Human 32
PIM1_HUMAN P11309 CHEMBL2147 Serine/threonine-protein Kinase PIM1, Human 28
CLK3_MOUSE O35492 CHEMBL1075282 Dual Specificity Protein Kinase CLK3, Mouse 25
CCNA2_HUMAN P20248 CHEMBL2582 Cyclin A2, Human 13
CCNT1_HUMAN O60563 CHEMBL2108 Cyclin T1, Human 13
CDK2_HUMAN P24941 CHEMBL301 Cyclin-dependent Kinase 2, Human 13
CDK9_HUMAN P50750 CHEMBL3116 Cyclin-dependent Kinase 9, Human 13
MK01_RAT P63086 CHEMBL5233 Mitogen-activated Protein Kinase 1, Rat 8
FLT3_HUMAN P36888 CHEMBL1974 Tyrosine-protein Kinase Receptor FLT3, Human 3
GSK3B_HUMAN P49841 CHEMBL262 Glycogen Synthase Kinase-3 Beta, Human 3
CDK5_HUMAN Q00535 CHEMBL4036 Cyclin-dependent Kinase 5, Human 2
KAPCA_HUMAN P17612 CHEMBL4101 CAMP-dependent Protein Kinase Alpha-catalytic Subunit, Human 2
KAPCB_HUMAN P22694 CHEMBL2918 CAMP-dependent Protein Kinase Beta-1 Catalytic Subunit, Human 2
KAPCG_HUMAN P22612 CHEMBL2743 CAMP-dependent Protein Kinase, Gamma Catalytic Subunit, Human 2
KGP1_HUMAN Q13976 CHEMBL4273 CGMP-dependent Protein Kinase 1 Beta, Human 2
KGP2_HUMAN Q13237 CHEMBL2896 CGMP-dependent Protein Kinase 2, Human 2
CCNB1_HUMAN P14635 CHEMBL2412 G2/mitotic-specific Cyclin B1, Human 1
CCNB2_HUMAN O95067 CHEMBL3723 G2/mitotic-specific Cyclin B2, Human 1
CCNB3_HUMAN Q8WWL7 CHEMBL3606 G2/mitotic-specific Cyclin B3, Human 1
CDK1_HUMAN P06493 CHEMBL308 Cyclin-dependent Kinase 1, Human 1
GSK3A_HUMAN P49840 CHEMBL2850 Glycogen Synthase Kinase-3 Alpha, Human 1
Z104299 Z104299 CHEMBL1907605 Cyclin-dependent Kinase 2/cyclin E1 1