UCSF

Cyclin-dependent Kinase 2/cyclin E1 (92 Compounds)

Swissprot:
Z104299
Stitch:
Z104299
UniProt:
Z104299
ChEMBL:
CHEMBL1907605

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 92 6 0 1
Binding ≤ 1μM 70 5 0 1

Reactome Network (0)

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
CDK5_HUMAN Q00535 CHEMBL4036 Cyclin-dependent Kinase 5, Human 34
Z104296 Z104296 CHEMBL1907602 Cyclin-dependent Kinase 1/cyclin B1 23
CDK2_HUMAN P24941 CHEMBL301 Cyclin-dependent Kinase 2, Human 22
Z104295 Z104295 CHEMBL1907601 Cyclin-dependent Kinase 4/cyclin D1 22
CCNA1_HUMAN P78396 CHEMBL3609 Cyclin A1, Human 20
Z104294 Z104294 CHEMBL1907600 Cyclin-dependent Kinase 5/CDK5 Activator 1 13
CCNT1_HUMAN O60563 CHEMBL2108 Cyclin T1, Human 4
CDK9_HUMAN P50750 CHEMBL3116 Cyclin-dependent Kinase 9, Human 4
GSK3B_HUMAN P49841 CHEMBL262 Glycogen Synthase Kinase-3 Beta, Human 4
ITK_HUMAN Q08881 CHEMBL2959 Tyrosine-protein Kinase ITK/TSK, Human 4
CCNH_HUMAN P51946 CHEMBL2165 Cyclin H, Human 3
CDK7_HUMAN P50613 CHEMBL3055 Cyclin-dependent Kinase 7, Human 3
FLT3_HUMAN P36888 CHEMBL1974 Tyrosine-protein Kinase Receptor FLT3, Human 3
INSR_HUMAN P06213 CHEMBL1981 Insulin Receptor, Human 3
MAT1_HUMAN P51948 CHEMBL5053 CDK-activating Kinase Assembly Factor MAT1, Human 3
AURKA_HUMAN O14965 CHEMBL4722 Serine/threonine-protein Kinase Aurora-A, Human 2
CCNA2_HUMAN P20248 CHEMBL2582 Cyclin A2, Human 2
CDK4_HUMAN P11802 CHEMBL331 Cyclin-dependent Kinase 4, Human 2
DYR1A_HUMAN Q13627 CHEMBL2292 Dual-specificity Tyrosine-phosphorylation Regulated Kinase 1A, Human 2
FGFR3_HUMAN P22607 CHEMBL2742 Fibroblast Growth Factor Receptor 3, Human 2
JAK2_HUMAN O60674 CHEMBL2971 Tyrosine-protein Kinase JAK2, Human 2
JAK3_HUMAN P52333 CHEMBL2148 Tyrosine-protein Kinase JAK3, Human 2
LCK_HUMAN P06239 CHEMBL258 Tyrosine-protein Kinase LCK, Human 2
NTRK1_HUMAN P04629 CHEMBL2815 Nerve Growth Factor Receptor Trk-A, Human 2
RET_HUMAN P07949 CHEMBL2041 Tyrosine-protein Kinase Receptor RET, Human 2
SRC_HUMAN P12931 CHEMBL267 Tyrosine-protein Kinase SRC, Human 2
VGFR2_HUMAN P35968 CHEMBL279 Vascular Endothelial Growth Factor Receptor 2, Human 2
VGFR3_HUMAN P35916 CHEMBL1955 Vascular Endothelial Growth Factor Receptor 3, Human 2
ABL1_HUMAN P00519 CHEMBL1862 Tyrosine-protein Kinase ABL, Human 1
ALK_HUMAN Q9UM73 CHEMBL4247 ALK Tyrosine Kinase Receptor, Human 1
AURKB_HUMAN Q96GD4 CHEMBL2185 Serine/threonine-protein Kinase Aurora-B, Human 1
AURKC_HUMAN Q9UQB9 CHEMBL3935 Serine/threonine-protein Kinase Aurora-C, Human 1
BRAF_HUMAN P15056 CHEMBL5145 Serine/threonine-protein Kinase B-raf, Human 1
CCNB1_HUMAN P14635 CHEMBL2412 G2/mitotic-specific Cyclin B1, Human 1
CCNB2_HUMAN O95067 CHEMBL3723 G2/mitotic-specific Cyclin B2, Human 1
CCNB3_HUMAN Q8WWL7 CHEMBL3606 G2/mitotic-specific Cyclin B3, Human 1
CCNE1_HUMAN P24864 CHEMBL3617 G1/S-specific Cyclin E1, Human 1
CCNE2_HUMAN O96020 CHEMBL2884 G1/S-specific Cyclin E2, Human 1
CCNT2_HUMAN O60583 CHEMBL1293321 Cyclin-T2, Human 1
CDK16_HUMAN Q00536 CHEMBL4597 Serine/threonine-protein Kinase PCTAIRE-1, Human 1
CDK1_HUMAN P06493 CHEMBL308 Cyclin-dependent Kinase 1, Human 1
CLK1_HUMAN P49759 CHEMBL4224 Dual Specificty Protein Kinase CLK1, Human 1
CLK2_HUMAN P49760 CHEMBL4225 Dual Specificity Protein Kinase CLK2, Human 1
CLK4_HUMAN Q9HAZ1 CHEMBL4203 Dual Specificity Protein Kinase CLK4, Human 1
DYR1A_MOUSE Q61214 CHEMBL4750 Dual-specificity Tyrosine-phosphorylation Regulated Kinase 1A, Mouse 1
DYR1A_RAT Q63470 CHEMBL5508 Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1A, Rat 1
DYR1B_HUMAN Q9Y463 CHEMBL5543 Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1B, Human 1
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 1
EPHA2_HUMAN P29317 CHEMBL2068 Ephrin Type-A Receptor 2, Human 1
EPHA3_HUMAN P29320 CHEMBL4954 Ephrin Type-A Receptor 3, Human 1
EPHA7_HUMAN Q15375 CHEMBL4602 Ephrin Type-A Receptor 7, Human 1
FAK2_HUMAN Q14289 CHEMBL5469 Protein Tyrosine Kinase 2 Beta, Human 1
FGFR1_HUMAN P11362 CHEMBL3650 Fibroblast Growth Factor Receptor 1, Human 1
FGFR2_HUMAN P21802 CHEMBL4142 Fibroblast Growth Factor Receptor 2, Human 1
FGFR4_HUMAN P22455 CHEMBL3973 Fibroblast Growth Factor Receptor 4, Human 1
IKKB_HUMAN O14920 CHEMBL1991 Inhibitor Of Nuclear Factor Kappa B Kinase Beta Subunit, Human 1
INSRR_HUMAN P14616 CHEMBL5483 Insulin Receptor-related Protein, Human 1
JAK1_HUMAN P23458 CHEMBL2835 Tyrosine-protein Kinase JAK1, Human 1
KC1A_HUMAN P48729 CHEMBL2793 Casein Kinase I Alpha, Human 1
KC1D_HUMAN P48730 CHEMBL2828 Casein Kinase I Delta, Human 1
KC1E_HUMAN P49674 CHEMBL4937 Casein Kinase I Epsilon, Human 1
KC1G1_HUMAN Q9HCP0 CHEMBL2426 Casein Kinase I Gamma 1, Human 1
KC1G2_HUMAN P78368 CHEMBL2543 Casein Kinase I Gamma 2, Human 1
KC1G3_HUMAN Q9Y6M4 CHEMBL5084 Casein Kinase I Isoform Gamma-3, Human 1
KIT_HUMAN P10721 CHEMBL1936 Stem Cell Growth Factor Receptor, Human 1
KKCC2_HUMAN Q96RR4 CHEMBL5284 CaM-kinase Kinase Beta, Human 1
KS6A2_HUMAN Q15349 CHEMBL3906 Ribosomal Protein S6 Kinase Alpha 2, Human 1
KS6B1_HUMAN P23443 CHEMBL4501 Ribosomal Protein S6 Kinase 1, Human 1
LYN_HUMAN P07948 CHEMBL3905 Tyrosine-protein Kinase Lyn, Human 1
MK01_HUMAN P28482 CHEMBL4040 MAP Kinase ERK2, Human 1
MK03_HUMAN P27361 CHEMBL3385 MAP Kinase ERK1, Human 1
MK15_HUMAN Q8TD08 CHEMBL5198 Mitogen-activated Protein Kinase 15, Human 1
MUSK_HUMAN O15146 CHEMBL5684 Muscle, Skeletal Receptor Tyrosine Protein Kinase, Human 1
PAK4_HUMAN O96013 CHEMBL4482 Serine/threonine-protein Kinase PAK 4, Human 1
PGFRA_HUMAN P16234 CHEMBL2007 Platelet-derived Growth Factor Receptor Alpha, Human 1
PGFRB_HUMAN P09619 CHEMBL1913 Platelet-derived Growth Factor Receptor Beta, Human 1
PLK1_HUMAN P53350 CHEMBL3024 Serine/threonine-protein Kinase PLK1, Human 1
PLK2_HUMAN Q9NYY3 CHEMBL5938 Serine/threonine-protein Kinase PLK2, Human 1
PLK3_HUMAN Q9H4B4 CHEMBL4897 Serine/threonine-protein Kinase PLK3, Human 1
TIE2_HUMAN Q02763 CHEMBL4128 Tyrosine-protein Kinase TIE-2, Human 1
TTK_HUMAN P33981 CHEMBL3983 Dual Specificity Protein Kinase TTK, Human 1
VGFR1_HUMAN P17948 CHEMBL1868 Vascular Endothelial Growth Factor Receptor 1, Human 1

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