UCSF

Cystic Fibrosis Transmembrane Conductance Regulator, Human (83 Compounds)

Swissprot:
CFTR_HUMAN
Stitch:
CFTR_HUMAN
UniProt:
P13569
ChEMBL:
CHEMBL4051
Reactome:
REACT_15480
PDB:
1NBD (DOCK)
1XMI (DOCK)
1XMJ (DOCK)
2BBO (DOCK)
2BBS (DOCK)
2BBT (DOCK)
2PZE (DOCK)
2PZF (DOCK)
2PZG (DOCK)
3GD7 (DOCK)
3ISW (DOCK)
CFTR

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 83 50 0 1
Binding ≤ 1μM 29 10 0 1
Functional ≤ 10μM 87 2 0 0

Reactome Network (1)

Reactome ID Description Species
REACT_15480 ABC-family proteins mediated transport Homo sapiens

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
CFTR-1-E Cystic Fibrosis Transmembrane Conductance Regulator (cluster #1 Of 2), Eukaryotic 81 50 0 1
CFTR-2-E Cystic Fibrosis Transmembrane Conductance Regulator (cluster #2 Of 2), Eukaryotic 2 0 0 0
Uniprot Swissprot Chembl Description Number Shared
Z102279 Z102279 CHEMBL613579 Kidney 2
CCNA1_HUMAN P78396 CHEMBL3609 Cyclin A1, Human 1
CCNA2_HUMAN P20248 CHEMBL2582 Cyclin A2, Human 1
CCNB1_HUMAN P14635 CHEMBL2412 G2/mitotic-specific Cyclin B1, Human 1
CCNB2_HUMAN O95067 CHEMBL3723 G2/mitotic-specific Cyclin B2, Human 1
CCNB3_HUMAN Q8WWL7 CHEMBL3606 G2/mitotic-specific Cyclin B3, Human 1
CCNE1_HUMAN P24864 CHEMBL3617 G1/S-specific Cyclin E1, Human 1
CCNE2_HUMAN O96020 CHEMBL2884 G1/S-specific Cyclin E2, Human 1
CDK1_HUMAN P06493 CHEMBL308 Cyclin-dependent Kinase 1, Human 1
CDK1_YEAST P00546 CHEMBL5213 Cell Division Control Protein 28, Yeast 1
CDK2_HUMAN P24941 CHEMBL301 Cyclin-dependent Kinase 2, Human 1
CDK5_HUMAN Q00535 CHEMBL4036 Cyclin-dependent Kinase 5, Human 1
GSK3A_HUMAN P49840 CHEMBL2850 Glycogen Synthase Kinase-3 Alpha, Human 1
GSK3B_HUMAN P49841 CHEMBL262 Glycogen Synthase Kinase-3 Beta, Human 1
MK08_HUMAN P45983 CHEMBL2276 C-Jun N-terminal Kinase 1, Human 1
MK09_HUMAN P45984 CHEMBL4179 C-Jun N-terminal Kinase 2, Human 1
MK10_HUMAN P53779 CHEMBL2637 C-Jun N-terminal Kinase 3, Human 1
Z104294 Z104294 CHEMBL1907600 Cyclin-dependent Kinase 5/CDK5 Activator 1 1

Most Common Rings