UCSF
Image of Pyrrolidine

Identity 99% 90% 80% 70% Substructure

Pyrrolidine

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Ring Information

Rings Ring Systems Atoms Carbons Nitrogens Oxygens Sulfurs
1 1 5 4 1 0 0

Subset Information

Substances Natural Purchasable Annotated BB In Man Last Updated
View 255 266,982 1,124 16,609 43 2012-03-06

Most Common Targets

Name (Uniprot) Swissprot ChEMBL Description Size Browse Download (Annotations)
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 86 Annotations Catalogs SMILES SDF Mol2 Flexibase
SC6A3_HUMAN Q01959 CHEMBL238 Dopamine Transporter, Human 68 Annotations Catalogs SMILES SDF Mol2 Flexibase
SC6A3_HUMAN Q01959 CHEMBL238 Dopamine Transporter, Human 59 Annotations Catalogs SMILES SDF Mol2 Flexibase
SC6A2_HUMAN P23975 CHEMBL222 Norepinephrine Transporter, Human 58 Annotations Catalogs SMILES SDF Mol2 Flexibase
SC6A4_HUMAN P31645 CHEMBL228 Serotonin Transporter, Human 55 Annotations Catalogs SMILES SDF Mol2 Flexibase
DPP4_HUMAN P27487 CHEMBL284 Dipeptidyl Peptidase IV, Human 53 Annotations Catalogs SMILES SDF Mol2 Flexibase
SC6A3_HUMAN Q01959 CHEMBL238 Dopamine Transporter, Human 53 Annotations Catalogs SMILES SDF Mol2 Flexibase
SC6A3_RAT P23977 CHEMBL338 Dopamine Transporter, Rat 52 Annotations Catalogs SMILES SDF Mol2 Flexibase
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 50 Annotations Catalogs SMILES SDF Mol2 Flexibase
SC6A3_RAT P23977 CHEMBL338 Dopamine Transporter, Rat 49 Annotations Catalogs SMILES SDF Mol2 Flexibase
DPP4_HUMAN P27487 CHEMBL284 Dipeptidyl Peptidase IV, Human 48 Annotations Catalogs SMILES SDF Mol2 Flexibase
SC6A2_HUMAN P23975 CHEMBL222 Norepinephrine Transporter, Human 47 Annotations Catalogs SMILES SDF Mol2 Flexibase
SC6A2_HUMAN P23975 CHEMBL222 Norepinephrine Transporter, Human 44 Annotations Catalogs SMILES SDF Mol2 Flexibase
SC6A4_HUMAN P31645 CHEMBL228 Serotonin Transporter, Human 43 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACES_HUMAN P22303 CHEMBL220 Acetylcholinesterase, Human 42 Annotations Catalogs SMILES SDF Mol2 Flexibase
HRH3_HUMAN Q9Y5N1 CHEMBL264 Histamine H3 Receptor, Human 42 Annotations Catalogs SMILES SDF Mol2 Flexibase
HRH3_HUMAN Q9Y5N1 CHEMBL264 Histamine H3 Receptor, Human 42 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRM_RAT P33535 CHEMBL270 Mu Opioid Receptor, Rat 42 Annotations Catalogs SMILES SDF Mol2 Flexibase
PCP_HUMAN P42785 CHEMBL2335 Lysosomal Pro-X Carboxypeptidase, Human 42 Annotations Catalogs SMILES SDF Mol2 Flexibase
NK1R_HUMAN P25103 CHEMBL249 Neurokinin 1 Receptor, Human 41 Annotations Catalogs SMILES SDF Mol2 Flexibase
NK1R_HUMAN P25103 CHEMBL249 Neurokinin 1 Receptor, Human 41 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCR2_HUMAN P41597 CHEMBL4015 C-C Chemokine Receptor Type 2, Human 40 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCR2_HUMAN P41597 CHEMBL4015 C-C Chemokine Receptor Type 2, Human 40 Annotations Catalogs SMILES SDF Mol2 Flexibase
HRH3_RAT Q9QYN8 CHEMBL4124 Histamine H3 Receptor, Rat 38 Annotations Catalogs SMILES SDF Mol2 Flexibase
HRH3_RAT Q9QYN8 CHEMBL4124 Histamine H3 Receptor, Rat 38 Annotations Catalogs SMILES SDF Mol2 Flexibase
PCP_HUMAN P42785 CHEMBL2335 Lysosomal Pro-X Carboxypeptidase, Human 37 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRK_HUMAN P41145 CHEMBL237 Kappa Opioid Receptor, Human 36 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50607 Z50607 CHEMBL378 Human Immunodeficiency Virus 1 33 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRM_RAT P33535 CHEMBL270 Mu Opioid Receptor, Rat 32 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRM_HUMAN P35372 CHEMBL233 Mu Opioid Receptor, Human 29 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT1D_HUMAN P28221 CHEMBL1983 Serotonin 1d (5-HT1d) Receptor, Human 27 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT1D_HUMAN P28221 CHEMBL1983 Serotonin 1d (5-HT1d) Receptor, Human 27 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT1B_HUMAN P28222 CHEMBL1898 Serotonin 1b (5-HT1b) Receptor, Human 26 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT1B_HUMAN P28222 CHEMBL1898 Serotonin 1b (5-HT1b) Receptor, Human 26 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRD_RAT P33533 CHEMBL269 Delta Opioid Receptor, Rat 26 Annotations Catalogs SMILES SDF Mol2 Flexibase
CASP3_HUMAN P42574 CHEMBL2334 Caspase-3, Human 24 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRK_HUMAN P41145 CHEMBL237 Kappa Opioid Receptor, Human 24 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADK_HUMAN P55263 CHEMBL3589 Adenosine Kinase, Human 23 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADK_HUMAN P55263 CHEMBL3589 Adenosine Kinase, Human 23 Annotations Catalogs SMILES SDF Mol2 Flexibase
CASP3_HUMAN P42574 CHEMBL2334 Caspase-3, Human 22 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRD_RAT P33533 CHEMBL269 Delta Opioid Receptor, Rat 22 Annotations Catalogs SMILES SDF Mol2 Flexibase
SC6A4_HUMAN P31645 CHEMBL228 Serotonin Transporter, Human 21 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCR5_HUMAN P51681 CHEMBL274 C-C Chemokine Receptor Type 5, Human 20 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCR5_HUMAN P51681 CHEMBL274 C-C Chemokine Receptor Type 5, Human 20 Annotations Catalogs SMILES SDF Mol2 Flexibase
DPP8_HUMAN Q6V1X1 CHEMBL4657 Dipeptidyl Peptidase VIII, Human 19 Annotations Catalogs SMILES SDF Mol2 Flexibase
MCHR1_HUMAN Q99705 CHEMBL344 Melanin-concentrating Hormone Receptor 1, Human 19 Annotations Catalogs SMILES SDF Mol2 Flexibase
MCHR1_HUMAN Q99705 CHEMBL344 Melanin-concentrating Hormone Receptor 1, Human 19 Annotations Catalogs SMILES SDF Mol2 Flexibase
TPP2_RAT Q64560 CHEMBL4675 Tripeptidyl Aminopeptidase, Rat 19 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80240 Z80240 CHEMBL614129 MDA-MB-361 19 Annotations Catalogs SMILES SDF Mol2 Flexibase
NPY5R_HUMAN Q15761 CHEMBL4561 Neuropeptide Y Receptor Type 5, Human 18 Annotations Catalogs SMILES SDF Mol2 Flexibase
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 17 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT1D_HUMAN P28221 CHEMBL1983 Serotonin 1d (5-HT1d) Receptor, Human 16 Annotations Catalogs SMILES SDF Mol2 Flexibase
MTOR_HUMAN P42345 CHEMBL2842 FK506 Binding Protein 12, Human 16 Annotations Catalogs SMILES SDF Mol2 Flexibase
MTOR_HUMAN P42345 CHEMBL2842 FK506 Binding Protein 12, Human 16 Annotations Catalogs SMILES SDF Mol2 Flexibase
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 16 Annotations Catalogs SMILES SDF Mol2 Flexibase
PK3CG_HUMAN P48736 CHEMBL3267 PI3-kinase P110-gamma Subunit, Human 16 Annotations Catalogs SMILES SDF Mol2 Flexibase
PK3CG_HUMAN P48736 CHEMBL3267 PI3-kinase P110-gamma Subunit, Human 16 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q8MMZ8_EIMTE Q8MMZ8 CHEMBL5036 CGMP-dependent Protein Kinase, Eimte 16 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q8MMZ8_EIMTE Q8MMZ8 CHEMBL5036 CGMP-dependent Protein Kinase, Eimte 16 Annotations Catalogs SMILES SDF Mol2 Flexibase
THRB_HUMAN P00734 CHEMBL204 Thrombin, Human 16 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80390 Z80390 CHEMBL390 PC-3 (Prostate Carcinoma Cells) 16 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACES_HUMAN P22303 CHEMBL220 Acetylcholinesterase, Human 15 Annotations Catalogs SMILES SDF Mol2 Flexibase
CASP7_HUMAN P55210 CHEMBL3468 Caspase-7, Human 15 Annotations Catalogs SMILES SDF Mol2 Flexibase
CASP7_HUMAN P55210 CHEMBL3468 Caspase-7, Human 15 Annotations Catalogs SMILES SDF Mol2 Flexibase
CP2D6_HUMAN P10635 CHEMBL289 Cytochrome P450 2D6, Human 15 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 15 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 15 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 15 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 15 Annotations Catalogs SMILES SDF Mol2 Flexibase
FA10_HUMAN P00742 CHEMBL244 Coagulation Factor X, Human 15 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRM_HUMAN P35372 CHEMBL233 Mu Opioid Receptor, Human 15 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACE_RAT P47820 CHEMBL2625 Angiotensin-converting Enzyme, Rat 14 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACE_RAT P47820 CHEMBL2625 Angiotensin-converting Enzyme, Rat 14 Annotations Catalogs SMILES SDF Mol2 Flexibase
FA10_HUMAN P00742 CHEMBL244 Coagulation Factor X, Human 14 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z104290 Z104290 CHEMBL1907596 Neuronal Acetylcholine Receptor; Alpha4/beta2 14 Annotations Catalogs SMILES SDF Mol2 Flexibase
CHLE_HUMAN P06276 CHEMBL1914 Butyrylcholinesterase, Human 13 Annotations Catalogs SMILES SDF Mol2 Flexibase
MTAP_HUMAN Q13126 CHEMBL4941 S-methyl-5-thioadenosine Phosphorylase, Human 13 Annotations Catalogs SMILES SDF Mol2 Flexibase
MTAP_HUMAN Q13126 CHEMBL4941 S-methyl-5-thioadenosine Phosphorylase, Human 13 Annotations Catalogs SMILES SDF Mol2 Flexibase
PCP_MOUSE Q7TMR0 CHEMBL1255149 Lysosomal Pro-X Carboxypeptidase, Mouse 13 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACM2_HUMAN P08172 CHEMBL211 Muscarinic Acetylcholine Receptor M2, Human 12 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACM2_RAT P10980 CHEMBL309 Muscarinic Acetylcholine Receptor M2, Rat 12 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACM2_RAT P10980 CHEMBL309 Muscarinic Acetylcholine Receptor M2, Rat 12 Annotations Catalogs SMILES SDF Mol2 Flexibase
PCP_MOUSE Q7TMR0 CHEMBL1255149 Lysosomal Pro-X Carboxypeptidase, Mouse 12 Annotations Catalogs SMILES SDF Mol2 Flexibase
SC6A4_RAT P31652 CHEMBL313 Serotonin Transporter, Rat 12 Annotations Catalogs SMILES SDF Mol2 Flexibase
THRB_HUMAN P00734 CHEMBL204 Thrombin, Human 12 Annotations Catalogs SMILES SDF Mol2 Flexibase
TPP2_RAT Q64560 CHEMBL4675 Tripeptidyl Aminopeptidase, Rat 12 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z104290 Z104290 CHEMBL1907596 Neuronal Acetylcholine Receptor; Alpha4/beta2 12 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50512 Z50512 CHEMBL369 Cavia Porcellus 12 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACM1_HUMAN P11229 CHEMBL216 Muscarinic Acetylcholine Receptor M1, Human 11 Annotations Catalogs SMILES SDF Mol2 Flexibase
AKT1_HUMAN P31749 CHEMBL4282 Serine/threonine-protein Kinase AKT, Human 11 Annotations Catalogs SMILES SDF Mol2 Flexibase
PPCE_RAT O70196 CHEMBL4035 Prolyl Endopeptidase, Rat 11 Annotations Catalogs SMILES SDF Mol2 Flexibase
SC6A4_RAT P31652 CHEMBL313 Serotonin Transporter, Rat 11 Annotations Catalogs SMILES SDF Mol2 Flexibase
SC6A9_HUMAN P48067 CHEMBL2337 Glycine Transporter 1, Human 11 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z104281 Z104281 CHEMBL1907587 Neuronal Acetylcholine Receptor; Alpha3/beta2 11 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z104286 Z104286 CHEMBL1907592 Neuronal Acetylcholine Receptor; Alpha2/beta2 11 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z104286 Z104286 CHEMBL1907592 Neuronal Acetylcholine Receptor; Alpha2/beta2 11 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z104289 Z104289 CHEMBL1907595 Neuronal Acetylcholine Receptor; Alpha4/beta4 11 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT3A_RAT P35563 CHEMBL2411 Serotonin 3a (5-HT3a) Receptor, Rat 10 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT3A_RAT P35563 CHEMBL2411 Serotonin 3a (5-HT3a) Receptor, Rat 10 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT3B_RAT Q9JJ16 CHEMBL3458 Serotonin 3b (5-HT3b) Receptor, Rat 10 Annotations Catalogs SMILES SDF Mol2 Flexibase