CCR2_HUMAN - C-C Chemokine Receptor Type 2, Human | ZINC Is Not Commercial - A database of commercially-available compounds

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	1,214	6	1	2
Binding ≤ 1μM	1,025	3	1	2
Functional ≤ 10μM	497	2	0	0

Reactome ID	Description	Species
REACT_115897	Beta defensins	Homo sapiens
REACT_15344	Chemokine receptors bind chemokines	Homo sapiens
REACT_19231	G alpha (i) signalling events	Homo sapiens

Uniprot	Swissprot	Chembl	Description	Number Shared
CCR1_HUMAN	P32246	CHEMBL2413	C-C Chemokine Receptor Type 1, Human	19
CCR3_HUMAN	P51677	CHEMBL3473	C-C Chemokine Receptor Type 3, Human	21
CCR4_HUMAN	P51679	CHEMBL2414	C-C Chemokine Receptor Type 4, Human	7
CCR5_HUMAN	P51681	CHEMBL274	C-C Chemokine Receptor Type 5, Human	38
CXCR1_HUMAN	P25024	CHEMBL4029	Interleukin-8 Receptor A, Human	2
CXCR2_HUMAN	P25025	CHEMBL2434	Interleukin-8 Receptor B, Human	2
CXCR4_HUMAN	P61073	CHEMBL2107	C-X-C Chemokine Receptor Type 4, Human	1

G alpha (i) signalling events

Uniprot	Swissprot	Chembl	Description	Number Shared
CCR1_HUMAN	P32246	CHEMBL2413	C-C Chemokine Receptor Type 1, Human	19
CCR3_HUMAN	P51677	CHEMBL3473	C-C Chemokine Receptor Type 3, Human	21
CCR4_HUMAN	P51679	CHEMBL2414	C-C Chemokine Receptor Type 4, Human	7
CCR5_HUMAN	P51681	CHEMBL274	C-C Chemokine Receptor Type 5, Human	38
CXCR1_HUMAN	P25024	CHEMBL4029	Interleukin-8 Receptor A, Human	2
CXCR2_HUMAN	P25025	CHEMBL2434	Interleukin-8 Receptor B, Human	2
CXCR4_HUMAN	P61073	CHEMBL2107	C-X-C Chemokine Receptor Type 4, Human	1
DRD2_HUMAN	P14416	CHEMBL217	Dopamine D2 Receptor, Human	2
DRD4_HUMAN	P21917	CHEMBL219	Dopamine D4 Receptor, Human	1

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
CCR2_MOUSE	P51683	CHEMBL5412	C-C Chemokine Receptor Type 2, Mouse	66	0	0	0
CCR2_RAT	O55193	CHEMBL1293204	C-C Chemokine Receptor Type 2, Rat	2	0	0	0

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
CCR1_HUMAN	P32246	CHEMBL2413	C-C Chemokine Receptor Type 1, Human	383	10	0	0
CCR3_HUMAN	P51677	CHEMBL3473	C-C Chemokine Receptor Type 3, Human	908	15	2	1
CCR4_HUMAN	P51679	CHEMBL2414	C-C Chemokine Receptor Type 4, Human	238	6	1	1
CCR5_HUMAN	P51681	CHEMBL274	C-C Chemokine Receptor Type 5, Human	1,843	7	2	4
CCR7_HUMAN	P32248	CHEMBL4594	C-C Chemokine Receptor Type 7, Human	1	0	0	0
CCR8_HUMAN	P51685	CHEMBL4596	C-C Chemokine Receptor Type 8, Human	68	3	0	0
CCR9_HUMAN	P51686	CHEMBL5815	C-C Chemokine Receptor Type 9, Human	1	0	0	0

Clustered By Gene (0)

Uniprot	Swissprot	Chembl	Description	Number Shared
KCNH2_HUMAN	Q12809	CHEMBL240	HERG, Human	81
CCR2_MOUSE	P51683	CHEMBL5412	C-C Chemokine Receptor Type 2, Mouse	70
CCR5_HUMAN	P51681	CHEMBL274	C-C Chemokine Receptor Type 5, Human	36
CCR3_HUMAN	P51677	CHEMBL3473	C-C Chemokine Receptor Type 3, Human	21
CCR1_HUMAN	P32246	CHEMBL2413	C-C Chemokine Receptor Type 1, Human	19
Z80548	Z80548	CHEMBL614245	THP-1 (Acute Monocytic Leukemia Cells)	9
NK1R_HUMAN	P25103	CHEMBL249	Neurokinin 1 Receptor, Human	4
CCR2_RAT	O55193	CHEMBL1293204	C-C Chemokine Receptor Type 2, Rat	3
CCR4_HUMAN	P51679	CHEMBL2414	C-C Chemokine Receptor Type 4, Human	3
5HT2A_BOVIN	Q75Z89	CHEMBL3446	Serotonin 2a (5-HT2a) Receptor, Bovin	2
5HT2A_HUMAN	P28223	CHEMBL224	Serotonin 2a (5-HT2a) Receptor, Human	2
5HT2C_HUMAN	P28335	CHEMBL225	Serotonin 2c (5-HT2c) Receptor, Human	2
5HT2C_RAT	P08909	CHEMBL324	Serotonin 2c (5-HT2c) Receptor, Rat	2
CCR3_MOUSE	P51678	CHEMBL3406	C-C Chemokine Receptor Type 3, Mouse	2
CCR3_RAT	O54814	CHEMBL3928	C-C Chemokine Receptor Type 3, Rat	2
CXCR1_HUMAN	P25024	CHEMBL4029	Interleukin-8 Receptor A, Human	2
CXCR2_HUMAN	P25025	CHEMBL2434	Interleukin-8 Receptor B, Human	2
DRD2_HUMAN	P14416	CHEMBL217	Dopamine D2 Receptor, Human	2
DRD2_RAT	P61169	CHEMBL339	Dopamine D2 Receptor, Rat	2
Q9WTR4_RAT	Q9WTR4	CHEMBL304	Norepinephrine Transporter, Rat	2
SC6A2_HUMAN	P23975	CHEMBL222	Norepinephrine Transporter, Human	2
SC6A3_BOVIN	P27922	CHEMBL2986	Dopamine Transporter, Bovin	2
SC6A3_HUMAN	Q01959	CHEMBL238	Dopamine Transporter, Human	2
SC6A4_HUMAN	P31645	CHEMBL228	Serotonin Transporter, Human	2
SC6A4_MOUSE	Q60857	CHEMBL4642	Serotonin Transporter, Mouse	2
5HT6R_HUMAN	P50406	CHEMBL3371	Serotonin 6 (5-HT6) Receptor, Human	1
CCR5_MOUSE	P51682	CHEMBL3676	C-C Chemokine Receptor Type 5, Mouse	1
CXCR4_HUMAN	P61073	CHEMBL2107	C-X-C Chemokine Receptor Type 4, Human	1
CXCR4_RAT	O08565	CHEMBL5556	C-X-C Chemokine Receptor Type 4, Rat	1
DRD4_HUMAN	P21917	CHEMBL219	Dopamine D4 Receptor, Human	1
Z100744	Z100744	CHEMBL613301	Monocytes	1
Z50587	Z50587	CHEMBL372	Homo Sapiens	1
Z50607	Z50607	CHEMBL378	Human Immunodeficiency Virus 1	1
Z80088	Z80088	CHEMBL613853	CHO (Ovarian Cells)	1
Z80107	Z80107	CHEMBL614564	COS-7 (Kidney Cells)	1
Z80285	Z80285	CHEMBL614177	MOLT-4 (Acute T-lymphoblastic Leukemia Cells)	1