UCSF

C-C Chemokine Receptor Type 4, Human (238 Compounds)

Swissprot:
CCR4_HUMAN
Stitch:
CCR4_HUMAN
UniProt:
P51679
ChEMBL:
CHEMBL2414
Reactome:
REACT_15344
REACT_19231
PDB:
CCR4

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 238 6 1 1
Binding ≤ 1μM 138 3 0 0
Functional ≤ 10μM 45 3 0 0

Reactome Network (2)

Reactome ID Description Species
REACT_15344 Chemokine receptors bind chemokines Homo sapiens
REACT_19231 G alpha (i) signalling events Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
CCR1_HUMAN P32246 CHEMBL2413 C-C Chemokine Receptor Type 1, Human 12
CCR2_HUMAN P41597 CHEMBL4015 C-C Chemokine Receptor Type 2, Human 7
CCR3_HUMAN P51677 CHEMBL3473 C-C Chemokine Receptor Type 3, Human 5
CCR5_HUMAN P51681 CHEMBL274 C-C Chemokine Receptor Type 5, Human 16
CCR7_HUMAN P32248 CHEMBL4594 C-C Chemokine Receptor Type 7, Human 1
CCR9_HUMAN P51686 CHEMBL5815 C-C Chemokine Receptor Type 9, Human 1
CXCR2_HUMAN P25025 CHEMBL2434 Interleukin-8 Receptor B, Human 1
CXCR4_HUMAN P61073 CHEMBL2107 C-X-C Chemokine Receptor Type 4, Human 1

G alpha (i) signalling events

Uniprot Swissprot Chembl Description Number Shared
CCR1_HUMAN P32246 CHEMBL2413 C-C Chemokine Receptor Type 1, Human 12
CCR2_HUMAN P41597 CHEMBL4015 C-C Chemokine Receptor Type 2, Human 7
CCR3_HUMAN P51677 CHEMBL3473 C-C Chemokine Receptor Type 3, Human 5
CCR5_HUMAN P51681 CHEMBL274 C-C Chemokine Receptor Type 5, Human 16
CCR7_HUMAN P32248 CHEMBL4594 C-C Chemokine Receptor Type 7, Human 1
CCR9_HUMAN P51686 CHEMBL5815 C-C Chemokine Receptor Type 9, Human 1
CXCR2_HUMAN P25025 CHEMBL2434 Interleukin-8 Receptor B, Human 1
CXCR4_HUMAN P61073 CHEMBL2107 C-X-C Chemokine Receptor Type 4, Human 1
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
CCR1_HUMAN P32246 CHEMBL2413 C-C Chemokine Receptor Type 1, Human 383 10 0 0
CCR2_HUMAN P41597 CHEMBL4015 C-C Chemokine Receptor Type 2, Human 1,214 6 1 2
CCR3_HUMAN P51677 CHEMBL3473 C-C Chemokine Receptor Type 3, Human 908 15 2 1
CCR5_HUMAN P51681 CHEMBL274 C-C Chemokine Receptor Type 5, Human 1,843 7 2 4
CCR7_HUMAN P32248 CHEMBL4594 C-C Chemokine Receptor Type 7, Human 1 0 0 0
CCR8_HUMAN P51685 CHEMBL4596 C-C Chemokine Receptor Type 8, Human 68 3 0 0
CCR9_HUMAN P51686 CHEMBL5815 C-C Chemokine Receptor Type 9, Human 1 0 0 0

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
CCR4_MOUSE P51680 CHEMBL5410 C-C Chemokine Receptor Type 4, Mouse 17
CCR5_HUMAN P51681 CHEMBL274 C-C Chemokine Receptor Type 5, Human 16
CCR1_HUMAN P32246 CHEMBL2413 C-C Chemokine Receptor Type 1, Human 12
CCR3_HUMAN P51677 CHEMBL3473 C-C Chemokine Receptor Type 3, Human 5
CCR2_HUMAN P41597 CHEMBL4015 C-C Chemokine Receptor Type 2, Human 3
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 3
CCR3_RAT O54814 CHEMBL3928 C-C Chemokine Receptor Type 3, Rat 2
Z80874 Z80874 CHEMBL393 CEM (T-cell Leukemia) 2
CCR1_MOUSE P51675 CHEMBL3872 C-C Chemokine Receptor Type 1, Mouse 1
CCR7_HUMAN P32248 CHEMBL4594 C-C Chemokine Receptor Type 7, Human 1
CCR9_HUMAN P51686 CHEMBL5815 C-C Chemokine Receptor Type 9, Human 1
CXCR2_HUMAN P25025 CHEMBL2434 Interleukin-8 Receptor B, Human 1
CXCR4_HUMAN P61073 CHEMBL2107 C-X-C Chemokine Receptor Type 4, Human 1
CXCR4_RAT O08565 CHEMBL5556 C-X-C Chemokine Receptor Type 4, Rat 1

Most Common Rings