UCSF

C-C Chemokine Receptor Type 3, Human (908 Compounds)

Swissprot:
CCR3_HUMAN
Stitch:
CCR3_HUMAN
UniProt:
P51677
ChEMBL:
CHEMBL3473
Reactome:
REACT_15344
REACT_19231
PDB:
CCR3

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 908 15 2 1
Binding ≤ 1μM 730 9 2 0
Functional ≤ 10μM 169 3 0 0

Reactome Network (2)

Reactome ID Description Species
REACT_15344 Chemokine receptors bind chemokines Homo sapiens
REACT_19231 G alpha (i) signalling events Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
CCR1_HUMAN P32246 CHEMBL2413 C-C Chemokine Receptor Type 1, Human 31
CCR2_HUMAN P41597 CHEMBL4015 C-C Chemokine Receptor Type 2, Human 21
CCR4_HUMAN P51679 CHEMBL2414 C-C Chemokine Receptor Type 4, Human 5
CCR5_HUMAN P51681 CHEMBL274 C-C Chemokine Receptor Type 5, Human 5
CXCR1_HUMAN P25024 CHEMBL4029 Interleukin-8 Receptor A, Human 2
CXCR2_HUMAN P25025 CHEMBL2434 Interleukin-8 Receptor B, Human 2

G alpha (i) signalling events

Uniprot Swissprot Chembl Description Number Shared
CCR1_HUMAN P32246 CHEMBL2413 C-C Chemokine Receptor Type 1, Human 31
CCR2_HUMAN P41597 CHEMBL4015 C-C Chemokine Receptor Type 2, Human 21
CCR4_HUMAN P51679 CHEMBL2414 C-C Chemokine Receptor Type 4, Human 5
CCR5_HUMAN P51681 CHEMBL274 C-C Chemokine Receptor Type 5, Human 5
CXCR1_HUMAN P25024 CHEMBL4029 Interleukin-8 Receptor A, Human 2
CXCR2_HUMAN P25025 CHEMBL2434 Interleukin-8 Receptor B, Human 2
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 18
MCHR1_HUMAN Q99705 CHEMBL344 Melanin-concentrating Hormone Receptor 1, Human 1
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
CCR3_MACMU P56483 CHEMBL5176 C-C Chemokine Receptor Type 3, Macmu 1 0 0 0
CCR3_MOUSE P51678 CHEMBL3406 C-C Chemokine Receptor Type 3, Mouse 10 2 0 0
CCR3_RAT O54814 CHEMBL3928 C-C Chemokine Receptor Type 3, Rat 7 0 0 0
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
CCR1_HUMAN P32246 CHEMBL2413 C-C Chemokine Receptor Type 1, Human 383 10 0 0
CCR2_HUMAN P41597 CHEMBL4015 C-C Chemokine Receptor Type 2, Human 1,214 6 1 2
CCR4_HUMAN P51679 CHEMBL2414 C-C Chemokine Receptor Type 4, Human 238 6 1 1
CCR5_HUMAN P51681 CHEMBL274 C-C Chemokine Receptor Type 5, Human 1,843 7 2 4
CCR7_HUMAN P32248 CHEMBL4594 C-C Chemokine Receptor Type 7, Human 1 0 0 0
CCR8_HUMAN P51685 CHEMBL4596 C-C Chemokine Receptor Type 8, Human 68 3 0 0
CCR9_HUMAN P51686 CHEMBL5815 C-C Chemokine Receptor Type 9, Human 1 0 0 0

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 39
CCR1_HUMAN P32246 CHEMBL2413 C-C Chemokine Receptor Type 1, Human 31
SC6A2_HUMAN P23975 CHEMBL222 Norepinephrine Transporter, Human 26
SC6A3_HUMAN Q01959 CHEMBL238 Dopamine Transporter, Human 26
SC6A4_HUMAN P31645 CHEMBL228 Serotonin Transporter, Human 25
5HT2A_BOVIN Q75Z89 CHEMBL3446 Serotonin 2a (5-HT2a) Receptor, Bovin 21
CCR2_HUMAN P41597 CHEMBL4015 C-C Chemokine Receptor Type 2, Human 21
5HT2C_RAT P08909 CHEMBL324 Serotonin 2c (5-HT2c) Receptor, Rat 18
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 18
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 17
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 16
CCR3_MOUSE P51678 CHEMBL3406 C-C Chemokine Receptor Type 3, Mouse 9
CCR3_RAT O54814 CHEMBL3928 C-C Chemokine Receptor Type 3, Rat 7
CCR4_HUMAN P51679 CHEMBL2414 C-C Chemokine Receptor Type 4, Human 5
CCR5_HUMAN P51681 CHEMBL274 C-C Chemokine Receptor Type 5, Human 5
Q9WTR4_RAT Q9WTR4 CHEMBL304 Norepinephrine Transporter, Rat 4
SC6A3_BOVIN P27922 CHEMBL2986 Dopamine Transporter, Bovin 4
SC6A4_MOUSE Q60857 CHEMBL4642 Serotonin Transporter, Mouse 4
5HT2A_RAT P14842 CHEMBL322 Serotonin 2a (5-HT2a) Receptor, Rat 3
CCR1_MOUSE P51675 CHEMBL3872 C-C Chemokine Receptor Type 1, Mouse 3
Z50587 Z50587 CHEMBL372 Homo Sapiens 3
CXCR1_HUMAN P25024 CHEMBL4029 Interleukin-8 Receptor A, Human 2
CXCR2_HUMAN P25025 CHEMBL2434 Interleukin-8 Receptor B, Human 2
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 2
CCR3_MACFA Q9BDS8 CHEMBL1075262 C-C Chemokine Receptor Type 3, Macfa 1
CCR3_MACMU P56483 CHEMBL5176 C-C Chemokine Receptor Type 3, Macmu 1
MCHR1_HUMAN Q99705 CHEMBL344 Melanin-concentrating Hormone Receptor 1, Human 1
US28_HCMVA P69332 CHEMBL4259 Human Herpesvirus 5 Chemokine Receptor, Hcmva 1
Z104304 Z104304 CHEMBL1907610 Adrenergic Receptor Alpha-1 1