ZINC 12

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Quick Search ZINC ID or SMILES

Names
Compounds (134)
Reactome (2)
Related By:
Pathway (0)
Organism (5)
Gene (0)
Org. Clust. (2)
ChEMBL (135)
Rings (5)

Serotonin 2a (5-HT2a) Receptor, Bovin (134 Compounds)

Swissprot:: 5HT2A_BOVIN
Stitch:: 5HT2A_BOVIN
UniProt:: Q75Z89
ChEMBL:: CHEMBL3446
Reactome:: REACT_209521; REACT_202251
PDB:: HTR2A

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	134	13	9	11
Binding ≤ 1μM	66	9	7	9

Reactome ID	Description	Species
REACT_209521	G alpha (q) signalling events	Bos taurus
REACT_202251	Serotonin receptors	Bos taurus

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
5HT2A_CANFA	O46635	CHEMBL5781	5-hydroxytryptamine Receptor 2A, Canine	1	0	0	0
5HT2A_HUMAN	P28223	CHEMBL224	Serotonin 2a (5-HT2a) Receptor, Human	2,122	202	55	44
5HT2A_MOUSE	P35363	CHEMBL5377	Serotonin 2a (5-HT2a) Receptor, Mouse	169	9	6	6
5HT2A_PIG	P50129	CHEMBL2490	Serotonin 2a (5-HT2a) Receptor, Pig	81	6	1	1
5HT2A_RAT	P14842	CHEMBL322	Serotonin 2a (5-HT2a) Receptor, Rat	2,538	306	92	100

Clustered By Gene (0)

Clustered By Organism (2)

Code	Description	Substances	Purchasable	Natural	In Man
5HT2A-1-E	Serotonin 2a (5-HT2a) Receptor (cluster #1 Of 3), Eukaryotic	4,353	322	100	96
5HT2A-2-E	Serotonin 2a (5-HT2a) Receptor (cluster #2 Of 3), Eukaryotic	530	142	16	25
5HT2A-3-E	Serotonin 2a (5-HT2a) Receptor (cluster #3 Of 3), Eukaryotic	18	2	1	1

Uniprot	Swissprot	Chembl	Description	Number Shared
DRD2_BOVIN	P20288	CHEMBL3998	Dopamine D2 Receptor, Bovin	78
5HT2C_HUMAN	P28335	CHEMBL225	Serotonin 2c (5-HT2c) Receptor, Human	76
5HT1A_RAT	P19327	CHEMBL273	Serotonin 1a (5-HT1a) Receptor, Rat	70
ADA1A_BOVIN	P18130	CHEMBL4892	Alpha-1a Adrenergic Receptor, Bovin	69
5HT1B_RAT	P28564	CHEMBL3459	Serotonin 1b (5-HT1b) Receptor, Rat	65
5HT1A_HUMAN	P08908	CHEMBL214	Serotonin 1a (5-HT1a) Receptor, Human	45
ADA2A_BOVIN	Q28838	CHEMBL4744	Alpha-2a Adrenergic Receptor, Bovin	42
5HT2A_HUMAN	P28223	CHEMBL224	Serotonin 2a (5-HT2a) Receptor, Human	38
5HT2C_RAT	P08909	CHEMBL324	Serotonin 2c (5-HT2c) Receptor, Rat	30
DRD2_HUMAN	P14416	CHEMBL217	Dopamine D2 Receptor, Human	29
DRD2_RAT	P61169	CHEMBL339	Dopamine D2 Receptor, Rat	29
5HT2B_HUMAN	P41595	CHEMBL1833	Serotonin 2b (5-HT2b) Receptor, Human	28
CCR3_HUMAN	P51677	CHEMBL3473	C-C Chemokine Receptor Type 3, Human	21
ADA1B_HUMAN	P35368	CHEMBL232	Alpha-1b Adrenergic Receptor, Human	18
ADA1D_HUMAN	P25100	CHEMBL223	Alpha-1d Adrenergic Receptor, Human	18
5HT1D_PIG	P79400	CHEMBL4105	Serotonin 1d (5-HT1d) Receptor, Pig	17
5HT3A_RAT	P35563	CHEMBL2411	Serotonin 3a (5-HT3a) Receptor, Rat	17
5HT3B_RAT	Q9JJ16	CHEMBL3458	Serotonin 3b (5-HT3b) Receptor, Rat	17
SGMR1_RAT	Q9R0C9	CHEMBL3602	Sigma Opioid Receptor, Rat	12
ADA1A_HUMAN	P35348	CHEMBL229	Alpha-1a Adrenergic Receptor, Human	11
ADA2A_RAT	P22909	CHEMBL327	Alpha-2a Adrenergic Receptor, Rat	11
DRD3_HUMAN	P35462	CHEMBL234	Dopamine D3 Receptor, Human	11
5HT2A_RAT	P14842	CHEMBL322	Serotonin 2a (5-HT2a) Receptor, Rat	10
5HT2B_RAT	P30994	CHEMBL323	Serotonin 2b (5-HT2b) Receptor, Rat	10
5HT1F_RAT	P30940	CHEMBL4646	Serotonin 1f (5-HT1f) Receptor, Rat	9
DRD1_BOVIN	Q95136	CHEMBL2967	Dopamine D1 Receptor, Bovin	9
5HT1D_RAT	P28565	CHEMBL5450	Serotonin 1d (5-HT1d) Receptor, Rat	8
5HT3A_HUMAN	P46098	CHEMBL1899	Serotonin 3a (5-HT3a) Receptor, Human	8
5HT3B_HUMAN	O95264	CHEMBL3895	Serotonin 3b (5-HT3b) Receptor, Human	8
5HT3C_HUMAN	Q8WXA8	CHEMBL4795	Serotonin 3c (5-HT3c) Receptor, Human	8
5HT3D_HUMAN	Q70Z44	CHEMBL4673	Serotonin 3d (5-HT3d) Receptor, Human	8
5HT3E_HUMAN	A5X5Y0	CHEMBL3812	Serotonin 3e (5-HT3e) Receptor, Human	8
ADA2A_HUMAN	P08913	CHEMBL1867	Alpha-2a Adrenergic Receptor, Human	8
ADA2B_RAT	P19328	CHEMBL266	Alpha-2b Adrenergic Receptor, Rat	8
ADA2C_HUMAN	P18825	CHEMBL1916	Alpha-2c Adrenergic Receptor, Human	8
HRH1_RAT	P31390	CHEMBL4701	Histamine H1 Receptor, Rat	8
5HT1A_MOUSE	Q64264	CHEMBL3737	Serotonin 1a (5-HT1a) Receptor, Mouse	7
5HT3B_MOUSE	Q9JHJ5	CHEMBL3781	Serotonin 3b (5-HT3b) Receptor, Mouse	7
ADA1A_RAT	P43140	CHEMBL319	Alpha-1a Adrenergic Receptor, Rat	7
ADA2B_HUMAN	P18089	CHEMBL1942	Alpha-2b Adrenergic Receptor, Human	7
ADA2C_RAT	P22086	CHEMBL314	Alpha-2c Adrenergic Receptor, Rat	7
HRH1_HUMAN	P35367	CHEMBL231	Histamine H1 Receptor, Human	7
KCNH2_HUMAN	Q12809	CHEMBL240	HERG, Human	7
Z104304	Z104304	CHEMBL1907610	Adrenergic Receptor Alpha-1	7
5HT1B_HUMAN	P28222	CHEMBL1898	Serotonin 1b (5-HT1b) Receptor, Human	6
SC6A3_BOVIN	P27922	CHEMBL2986	Dopamine Transporter, Bovin	6
SC6A3_HUMAN	Q01959	CHEMBL238	Dopamine Transporter, Human	6
SC6A4_HUMAN	P31645	CHEMBL228	Serotonin Transporter, Human	6
5HT1D_HUMAN	P28221	CHEMBL1983	Serotonin 1d (5-HT1d) Receptor, Human	5
ADA1D_RAT	P23944	CHEMBL326	Alpha-1d Adrenergic Receptor, Rat	5
DRD1_RAT	P18901	CHEMBL265	Dopamine D1 Receptor, Rat	5
DRD3_RAT	P19020	CHEMBL3138	Dopamine D3 Receptor, Rat	5
DRD4_HUMAN	P21917	CHEMBL219	Dopamine D4 Receptor, Human	5
Q9WTR4_RAT	Q9WTR4	CHEMBL304	Norepinephrine Transporter, Rat	5
SGMR1_HUMAN	Q99720	CHEMBL287	Sigma Opioid Receptor, Human	5
5HT7R_HUMAN	P34969	CHEMBL3155	Serotonin 7 (5-HT7) Receptor, Human	4
5HT7R_RAT	P32305	CHEMBL3223	Serotonin 7 (5-HT7) Receptor, Rat	4
CCR3_MOUSE	P51678	CHEMBL3406	C-C Chemokine Receptor Type 3, Mouse	4
CCR3_RAT	O54814	CHEMBL3928	C-C Chemokine Receptor Type 3, Rat	4
DRD1_HUMAN	P21728	CHEMBL2056	Dopamine D1 Receptor, Human	4
DRD1_PIG	P50130	CHEMBL5067	Dopamine D1 Receptor, Pig	4
HRH1_CAVPO	P31389	CHEMBL3943	Histamine H1 Receptor, Guinea Pig	4
SC6A2_HUMAN	P23975	CHEMBL222	Norepinephrine Transporter, Human	4
SC6A4_MOUSE	Q60857	CHEMBL4642	Serotonin Transporter, Mouse	4
5HT4R_CAVPO	O70528	CHEMBL5017	Serotonin 4 (5-HT4) Receptor, Guinea Pig	3
5HT5A_HUMAN	P47898	CHEMBL3426	Serotonin 5a (5-HT5a) Receptor, Human	3
5HT6R_HUMAN	P50406	CHEMBL3371	Serotonin 6 (5-HT6) Receptor, Human	3
AA3R_HUMAN	P33765	CHEMBL256	Adenosine A3 Receptor, Human	3
DRD4_RAT	P30729	CHEMBL3361	Dopamine D4 Receptor, Rat	3
DRD5_RAT	P25115	CHEMBL2281	Dopamine D5 Receptor, Rat	3
5HT1E_HUMAN	P28566	CHEMBL2182	Serotonin 1e (5-HT1e) Receptor, Human	2
5HT2A_MOUSE	P35363	CHEMBL5377	Serotonin 2a (5-HT2a) Receptor, Mouse	2
5HT2B_MOUSE	Q02152	CHEMBL2583	Serotonin 2b (5-HT2b) Receptor, Mouse	2
5HT2C_MOUSE	P34968	CHEMBL3006	Serotonin 2c (5-HT2c) Receptor, Mouse	2
5HT3A_CAVPO	O70212	CHEMBL3666	Serotonin 3a (5-HT3a) Receptor, Guinea Pig	2
5HT3A_MOUSE	P23979	CHEMBL4972	Serotonin 3a (5-HT3a) Receptor, Mouse	2
5HT4R_HUMAN	Q13639	CHEMBL1875	Serotonin 4 (5-HT4) Receptor, Human	2
AA2BR_RAT	P29276	CHEMBL2592	Adenosine A2b Receptor, Rat	2
ACM1_HUMAN	P11229	CHEMBL216	Muscarinic Acetylcholine Receptor M1, Human	2
ACM1_RAT	P08482	CHEMBL276	Muscarinic Acetylcholine Receptor M1, Rat	2
ACM2_HUMAN	P08172	CHEMBL211	Muscarinic Acetylcholine Receptor M2, Human	2
ACM2_RAT	P10980	CHEMBL309	Muscarinic Acetylcholine Receptor M2, Rat	2
ACM3_HUMAN	P20309	CHEMBL245	Muscarinic Acetylcholine Receptor M3, Human	2
ACM4_HUMAN	P08173	CHEMBL1821	Muscarinic Acetylcholine Receptor M4, Human	2
ACM5_HUMAN	P08912	CHEMBL2035	Muscarinic Acetylcholine Receptor M5, Human	2
ADA1B_RAT	P15823	CHEMBL315	Alpha-1b Adrenergic Receptor, Rat	2
CCKAR_RAT	P30551	CHEMBL2871	Cholecystokinin A Receptor, Rat	2
CCR1_HUMAN	P32246	CHEMBL2413	C-C Chemokine Receptor Type 1, Human	2
CCR2_HUMAN	P41597	CHEMBL4015	C-C Chemokine Receptor Type 2, Human	2
CCR5_HUMAN	P51681	CHEMBL274	C-C Chemokine Receptor Type 5, Human	2
CXCR1_HUMAN	P25024	CHEMBL4029	Interleukin-8 Receptor A, Human	2
CXCR2_HUMAN	P25025	CHEMBL2434	Interleukin-8 Receptor B, Human	2
DRD1_MOUSE	Q61616	CHEMBL3071	Dopamine D1 Receptor, Mouse	2
DRD2_CHLAE	P52702	CHEMBL5456	Dopamine D2 Receptor, Chlae	2
DRD5_HUMAN	P21918	CHEMBL1850	Dopamine D5 Receptor, Human	2
HRH2_HUMAN	P25021	CHEMBL1941	Histamine H2 Receptor, Human	2
MCHR1_HUMAN	Q99705	CHEMBL344	Melanin-concentrating Hormone Receptor 1, Human	2
Q63380_RAT	Q63380	CHEMBL6184	Transporter, Rat	2
Z104303	Z104303	CHEMBL1907609	Muscarinic Acetylcholine Receptor	2
5HT2A_PIG	P50129	CHEMBL2490	Serotonin 2a (5-HT2a) Receptor, Pig	1
ACM3_RAT	P08483	CHEMBL320	Muscarinic Acetylcholine Receptor M3, Rat	1
ACM4_RAT	P08485	CHEMBL317	Muscarinic Acetylcholine Receptor M4, Rat	1
ADRB2_HUMAN	P07550	CHEMBL210	Beta-2 Adrenergic Receptor, Human	1
AP2S1_RAT	P62744	CHEMBL1697667	AP-2 Complex Subunit Sigma, Rat	1
DRD2_MOUSE	P61168	CHEMBL3427	Dopamine D2 Receptor, Mouse	1
EBP_HUMAN	Q15125	CHEMBL4931	3-beta-hydroxysteroid-delta(8),delta(7)-isomerase, Human	1
ERG2_YEAST	P32352	CHEMBL3224	C-8 Sterol Isomerase, Yeast	1
HRH2_RAT	P25102	CHEMBL4654	Histamine H2 Receptor, Rat	1
HRH3_RAT	Q9QYN8	CHEMBL4124	Histamine H3 Receptor, Rat	1
HRH4_HUMAN	Q9H3N8	CHEMBL3759	Histamine H4 Receptor, Human	1
HRH4_RAT	Q91ZY1	CHEMBL4468	Histamine H4 Receptor, Rat	1
MDR1_HUMAN	P08183	CHEMBL4302	P-glycoprotein 1, Human	1
NMD3A_HUMAN	Q8TCU5	CHEMBL4787	Glutamate [NMDA] Receptor Subunit 3A, Human	1
NMD3A_RAT	Q9R1M7	CHEMBL342	Glutamate [NMDA] Receptor Subunit 3A, Rat	1
NMD3B_HUMAN	O60391	CHEMBL2913	Glutamate [NMDA] Receptor Subunit 3B, Human	1
NMD3B_RAT	Q8VHN2	CHEMBL282	Glutamate [NMDA] Receptor Subunit 3B, Rat	1
NMDE1_HUMAN	Q12879	CHEMBL1972	Glutamate [NMDA] Receptor Subunit Epsilon 1, Human	1
NMDE2_HUMAN	Q13224	CHEMBL1904	Glutamate [NMDA] Receptor Subunit Epsilon 2, Human	1
NMDE2_RAT	Q00960	CHEMBL311	Glutamate [NMDA] Receptor Subunit Epsilon 2, Rat	1
NMDE3_HUMAN	Q14957	CHEMBL4109	Glutamate [NMDA] Receptor Subunit Epsilon 3, Human	1
NMDE4_HUMAN	O15399	CHEMBL2591	Glutamate [NMDA] Receptor Subunit Epsilon 4, Human	1
NMDZ1_HUMAN	Q05586	CHEMBL2015	Glutamate (NMDA) Receptor Subunit Zeta 1, Human	1
NMDZ1_RAT	P35439	CHEMBL330	Glutamate (NMDA) Receptor Subunit Zeta 1, Rat	1
OPRD_RAT	P33533	CHEMBL269	Delta Opioid Receptor, Rat	1
OPRK_RAT	P34975	CHEMBL3614	Kappa Opioid Receptor, Rat	1
OPRM_RAT	P33535	CHEMBL270	Mu Opioid Receptor, Rat	1
Q4U254_9ENTO	Q4U254	CHEMBL2857	Human Rhinovirus A Protease, 9ento	1
Q72874_9HIV1	Q72874	CHEMBL243	Human Immunodeficiency Virus Type 1 Protease, 9hiv1	1
SC6A4_RAT	P31652	CHEMBL313	Serotonin Transporter, Rat	1
SCN1A_HUMAN	P35498	CHEMBL1845	Sodium Channel Protein Type I Alpha Subunit, Human	1
SCN2A_HUMAN	Q99250	CHEMBL4187	Sodium Channel Protein Type II Alpha Subunit, Human	1
SCN3A_HUMAN	Q9NY46	CHEMBL5163	Sodium Channel Protein Type III Alpha Subunit, Human	1
SCN8A_HUMAN	Q9UQD0	CHEMBL5202	Sodium Channel Protein Type VIII Alpha Subunit, Human	1
SGMR1_CAVPO	Q60492	CHEMBL4153	Sigma-1 Receptor, Guinea Pig	1
Z100491	Z100491	CHEMBL613288	Sigma 2 Receptor	1