UCSF

Dopamine D2 Receptor, Mouse (137 Compounds)

Swissprot:
DRD2_MOUSE
Stitch:
DRD2_MOUSE
UniProt:
P61168
ChEMBL:
CHEMBL3427
Reactome:
REACT_253535
REACT_250376
PDB:
Drd2

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 137 8 4 4
Binding ≤ 1μM 73 4 4 4

Reactome Network (2)

Reactome ID Description Species
REACT_253535 Dopamine receptors Mus musculus
REACT_250376 G alpha (i) signalling events Mus musculus
Uniprot Swissprot Chembl Description Number Shared
DRD1_MOUSE Q61616 CHEMBL3071 Dopamine D1 Receptor, Mouse 1

G alpha (i) signalling events

Uniprot Swissprot Chembl Description Number Shared
5HT1A_MOUSE Q64264 CHEMBL3737 Serotonin 1a (5-HT1a) Receptor, Mouse 22
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
DRD2_BOVIN P20288 CHEMBL3998 Dopamine D2 Receptor, Bovin 425 51 18 25
DRD2_CANFA Q9GJU1 CHEMBL2703 Dopamine D2 Receptor, Canine 2 2 2 2
DRD2_CHLAE P52702 CHEMBL5456 Dopamine D2 Receptor, Chlae 14 2 2 2
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 3,672 241 71 74
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 4,526 318 108 115
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
DRD1_MOUSE Q61616 CHEMBL3071 Dopamine D1 Receptor, Mouse 19 4 2 4
DRD4_MOUSE P51436 CHEMBL2574 Dopamine D4 Receptor, Mouse 18 1 0 0

Clustered By Gene (0)

Clustered By Organism (23)

Code Description Substances Purchasable Natural In Man
DRD2-1-E Dopamine D2 Receptor (cluster #1 Of 24), Eukaryotic 33 2 1 1
DRD2-10-E Dopamine D2 Receptor (cluster #10 Of 24), Eukaryotic 25 2 0 0
DRD2-11-E Dopamine D2 Receptor (cluster #11 Of 24), Eukaryotic 86 16 2 4
DRD2-12-E Dopamine D2 Receptor (cluster #12 Of 24), Eukaryotic 3 0 0 0
DRD2-13-E Dopamine D2 Receptor (cluster #13 Of 24), Eukaryotic 1 0 0 0
DRD2-14-E Dopamine D2 Receptor (cluster #14 Of 24), Eukaryotic 70 19 12 15
DRD2-15-E Dopamine D2 Receptor (cluster #15 Of 24), Eukaryotic 339 16 9 10
DRD2-16-E Dopamine D2 Receptor (cluster #16 Of 24), Eukaryotic 114 17 6 3
DRD2-17-E Dopamine D2 Receptor (cluster #17 Of 24), Eukaryotic 1,119 52 13 21
DRD2-18-E Dopamine D2 Receptor (cluster #18 Of 24), Eukaryotic 103 3 1 3
DRD2-19-E Dopamine D2 Receptor (cluster #19 Of 24), Eukaryotic 62 0 0 0
DRD2-2-E Dopamine D2 Receptor (cluster #2 Of 24), Eukaryotic 2,742 230 57 42
DRD2-20-E Dopamine D2 Receptor (cluster #20 Of 24), Eukaryotic 171 6 2 3
DRD2-21-E Dopamine D2 Receptor (cluster #21 Of 24), Eukaryotic 41 0 0 0
DRD2-22-E Dopamine D2 Receptor (cluster #22 Of 24), Eukaryotic 30 20 4 4
DRD2-23-E Dopamine D2 Receptor (cluster #23 Of 24), Eukaryotic 381 15 7 9
DRD2-24-E Dopamine D2 Receptor (cluster #24 Of 24), Eukaryotic 1 1 1 1
DRD2-3-E Dopamine D2 Receptor (cluster #3 Of 24), Eukaryotic 265 14 7 7
DRD2-4-E Dopamine D2 Receptor (cluster #4 Of 24), Eukaryotic 1,893 45 14 24
DRD2-5-E Dopamine D2 Receptor (cluster #5 Of 24), Eukaryotic 28 1 0 0
DRD2-6-E Dopamine D2 Receptor (cluster #6 Of 24), Eukaryotic 454 25 4 5
DRD2-7-E Dopamine D2 Receptor (cluster #7 Of 24), Eukaryotic 81 8 4 4
DRD2-8-E Dopamine D2 Receptor (cluster #8 Of 24), Eukaryotic 184 8 1 2
DRD2-9-E Dopamine D2 Receptor (cluster #9 Of 24), Eukaryotic 327 17 2 2
Uniprot Swissprot Chembl Description Number Shared
SGMR1_MOUSE O55242 CHEMBL3465 Sigma Opioid Receptor, Mouse 102
5HT2C_MOUSE P34968 CHEMBL3006 Serotonin 2c (5-HT2c) Receptor, Mouse 98
5HT2A_MOUSE P35363 CHEMBL5377 Serotonin 2a (5-HT2a) Receptor, Mouse 96
5HT2B_MOUSE Q02152 CHEMBL2583 Serotonin 2b (5-HT2b) Receptor, Mouse 96
5HT1A_MOUSE Q64264 CHEMBL3737 Serotonin 1a (5-HT1a) Receptor, Mouse 22
5HT2A_RAT P14842 CHEMBL322 Serotonin 2a (5-HT2a) Receptor, Rat 12
5HT2C_RAT P08909 CHEMBL324 Serotonin 2c (5-HT2c) Receptor, Rat 11
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 10
DRD1_RAT P18901 CHEMBL265 Dopamine D1 Receptor, Rat 9
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 8
5HT1A_RAT P19327 CHEMBL273 Serotonin 1a (5-HT1a) Receptor, Rat 7
5HT2B_RAT P30994 CHEMBL323 Serotonin 2b (5-HT2b) Receptor, Rat 7
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 6
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 6
DRD5_RAT P25115 CHEMBL2281 Dopamine D5 Receptor, Rat 6
SGMR1_HUMAN Q99720 CHEMBL287 Sigma Opioid Receptor, Human 6
Z104304 Z104304 CHEMBL1907610 Adrenergic Receptor Alpha-1 6
SC6A4_HUMAN P31645 CHEMBL228 Serotonin Transporter, Human 5
ADA2A_RAT P22909 CHEMBL327 Alpha-2a Adrenergic Receptor, Rat 4
DRD3_RAT P19020 CHEMBL3138 Dopamine D3 Receptor, Rat 4
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 4
DRD5_HUMAN P21918 CHEMBL1850 Dopamine D5 Receptor, Human 4
5HT1B_RAT P28564 CHEMBL3459 Serotonin 1b (5-HT1b) Receptor, Rat 3
5HT1D_RAT P28565 CHEMBL5450 Serotonin 1d (5-HT1d) Receptor, Rat 3
5HT1F_RAT P30940 CHEMBL4646 Serotonin 1f (5-HT1f) Receptor, Rat 3
5HT2B_HUMAN P41595 CHEMBL1833 Serotonin 2b (5-HT2b) Receptor, Human 3
5HT7R_RAT P32305 CHEMBL3223 Serotonin 7 (5-HT7) Receptor, Rat 3
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 3
ADA1A_RAT P43140 CHEMBL319 Alpha-1a Adrenergic Receptor, Rat 3
ADA2A_HUMAN P08913 CHEMBL1867 Alpha-2a Adrenergic Receptor, Human 3
DRD1_HUMAN P21728 CHEMBL2056 Dopamine D1 Receptor, Human 3
DRD4_RAT P30729 CHEMBL3361 Dopamine D4 Receptor, Rat 3
HRH1_HUMAN P35367 CHEMBL231 Histamine H1 Receptor, Human 3
HRH1_RAT P31390 CHEMBL4701 Histamine H1 Receptor, Rat 3
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 3
SC6A4_MOUSE Q60857 CHEMBL4642 Serotonin Transporter, Mouse 3
SGMR1_RAT Q9R0C9 CHEMBL3602 Sigma Opioid Receptor, Rat 3
Z100491 Z100491 CHEMBL613288 Sigma 2 Receptor 3
Z104303 Z104303 CHEMBL1907609 Muscarinic Acetylcholine Receptor 3
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 2
5HT6R_HUMAN P50406 CHEMBL3371 Serotonin 6 (5-HT6) Receptor, Human 2
5HT7R_HUMAN P34969 CHEMBL3155 Serotonin 7 (5-HT7) Receptor, Human 2
ACM1_HUMAN P11229 CHEMBL216 Muscarinic Acetylcholine Receptor M1, Human 2
ACM2_HUMAN P08172 CHEMBL211 Muscarinic Acetylcholine Receptor M2, Human 2
ACM3_HUMAN P20309 CHEMBL245 Muscarinic Acetylcholine Receptor M3, Human 2
ACM4_HUMAN P08173 CHEMBL1821 Muscarinic Acetylcholine Receptor M4, Human 2
ACM5_HUMAN P08912 CHEMBL2035 Muscarinic Acetylcholine Receptor M5, Human 2
ADA1A_HUMAN P35348 CHEMBL229 Alpha-1a Adrenergic Receptor, Human 2
ADA1B_HUMAN P35368 CHEMBL232 Alpha-1b Adrenergic Receptor, Human 2
ADA1B_RAT P15823 CHEMBL315 Alpha-1b Adrenergic Receptor, Rat 2
ADA1D_HUMAN P25100 CHEMBL223 Alpha-1d Adrenergic Receptor, Human 2
ADA1D_RAT P23944 CHEMBL326 Alpha-1d Adrenergic Receptor, Rat 2
ADA2B_HUMAN P18089 CHEMBL1942 Alpha-2b Adrenergic Receptor, Human 2
ADA2B_RAT P19328 CHEMBL266 Alpha-2b Adrenergic Receptor, Rat 2
ADA2C_HUMAN P18825 CHEMBL1916 Alpha-2c Adrenergic Receptor, Human 2
ADA2C_RAT P22086 CHEMBL314 Alpha-2c Adrenergic Receptor, Rat 2
DRD1_BOVIN Q95136 CHEMBL2967 Dopamine D1 Receptor, Bovin 2
DRD1_PIG P50130 CHEMBL5067 Dopamine D1 Receptor, Pig 2
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 2
HRH2_RAT P25102 CHEMBL4654 Histamine H2 Receptor, Rat 2
HRH3_RAT Q9QYN8 CHEMBL4124 Histamine H3 Receptor, Rat 2
HRH4_RAT Q91ZY1 CHEMBL4468 Histamine H4 Receptor, Rat 2
Q9WTR4_RAT Q9WTR4 CHEMBL304 Norepinephrine Transporter, Rat 2
SC6A2_HUMAN P23975 CHEMBL222 Norepinephrine Transporter, Human 2
SC6A2_MOUSE O55192 CHEMBL2370 Norepinephrine Transporter, Mouse 2
SCN1A_HUMAN P35498 CHEMBL1845 Sodium Channel Protein Type I Alpha Subunit, Human 2
SCN2A_HUMAN Q99250 CHEMBL4187 Sodium Channel Protein Type II Alpha Subunit, Human 2
SCN3A_HUMAN Q9NY46 CHEMBL5163 Sodium Channel Protein Type III Alpha Subunit, Human 2
SCN8A_HUMAN Q9UQD0 CHEMBL5202 Sodium Channel Protein Type VIII Alpha Subunit, Human 2
SGMR1_CAVPO Q60492 CHEMBL4153 Sigma-1 Receptor, Guinea Pig 2
5HT1E_HUMAN P28566 CHEMBL2182 Serotonin 1e (5-HT1e) Receptor, Human 1
5HT2A_BOVIN Q75Z89 CHEMBL3446 Serotonin 2a (5-HT2a) Receptor, Bovin 1
5HT3A_HUMAN P46098 CHEMBL1899 Serotonin 3a (5-HT3a) Receptor, Human 1
5HT3A_MOUSE P23979 CHEMBL4972 Serotonin 3a (5-HT3a) Receptor, Mouse 1
5HT3A_RAT P35563 CHEMBL2411 Serotonin 3a (5-HT3a) Receptor, Rat 1
5HT3B_RAT Q9JJ16 CHEMBL3458 Serotonin 3b (5-HT3b) Receptor, Rat 1
5HT4R_RAT Q62758 CHEMBL4317 Serotonin 4 (5-HT4) Receptor, Rat 1
5HT5A_HUMAN P47898 CHEMBL3426 Serotonin 5a (5-HT5a) Receptor, Human 1
5HT5A_RAT P35364 CHEMBL4655 Serotonin 5a (5-HT5a) Receptor, Rat 1
5HT5B_RAT P35365 CHEMBL2619 Serotonin 5b (5-HT5b) Receptor, Rat 1
5HT6R_RAT P31388 CHEMBL3372 Serotonin 6 (5-HT6) Receptor, Rat 1
ACM1_RAT P08482 CHEMBL276 Muscarinic Acetylcholine Receptor M1, Rat 1
ACM2_RAT P10980 CHEMBL309 Muscarinic Acetylcholine Receptor M2, Rat 1
ACM3_RAT P08483 CHEMBL320 Muscarinic Acetylcholine Receptor M3, Rat 1
ACM4_RAT P08485 CHEMBL317 Muscarinic Acetylcholine Receptor M4, Rat 1
ACM5_RAT P08911 CHEMBL277 Muscarinic Acetylcholine Receptor M5, Rat 1
ADA1A_BOVIN P18130 CHEMBL4892 Alpha-1a Adrenergic Receptor, Bovin 1
ADCY1_HUMAN Q08828 CHEMBL2899 Brain Adenylate Cyclase 1, Human 1
ADCY2_HUMAN Q08462 CHEMBL3760 Adenylate Cyclase Type II, Human 1
ADCY2_RAT P26769 CHEMBL2958 Adenylate Cyclase Type II, Rat 1
ADCY3_RAT P21932 CHEMBL4864 Adenylate Cyclase Type III, Rat 1
ADCY4_RAT P26770 CHEMBL2879 Adenylate Cyclase Type IV, Rat 1
ADCY5_HUMAN O95622 CHEMBL3189 Adenylate Cyclase Type V, Human 1
ADCY5_RAT Q04400 CHEMBL2880 Adenylate Cyclase Type V, Rat 1
ADCY6_RAT Q03343 CHEMBL2975 Adenylate Cyclase Type VI, Rat 1
ADCY8_HUMAN P40145 CHEMBL2960 Adenylate Cyclase Type VIII, Human 1
ADCY8_RAT P40146 CHEMBL3082 Adenylate Cyclase Type VIII, Rat 1
ADRB1_RAT P18090 CHEMBL3252 Beta-1 Adrenergic Receptor, Rat 1
ADRB2_RAT P10608 CHEMBL3754 Beta-2 Adrenergic Receptor, Rat 1
ADRB3_RAT P26255 CHEMBL4031 Beta-3 Adrenergic Receptor, Rat 1
DRD1_MOUSE Q61616 CHEMBL3071 Dopamine D1 Receptor, Mouse 1
DRD2_BOVIN P20288 CHEMBL3998 Dopamine D2 Receptor, Bovin 1
DRD2_CHLAE P52702 CHEMBL5456 Dopamine D2 Receptor, Chlae 1
HRH4_HUMAN Q9H3N8 CHEMBL3759 Histamine H4 Receptor, Human 1
PRIO_HUMAN P04156 CHEMBL4869 Prion Protein, Human 1
Q63380_RAT Q63380 CHEMBL6184 Transporter, Rat 1
Q8CFM9_RAT Q8CFM9 CHEMBL3940 Adenylate Cyclase Type VII, Rat 1
SC6A3_MOUSE Q61327 CHEMBL2799 Dopamine Transporter, Mouse 1
SC6A4_RAT P31652 CHEMBL313 Serotonin Transporter, Rat 1
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 1