UCSF

Dopamine Transporter, Mouse (55 Compounds)

Swissprot:
SC6A3_MOUSE
Stitch:
SC6A3_MOUSE
UniProt:
Q61327
ChEMBL:
CHEMBL2799
Reactome:
REACT_231512
REACT_253228
PDB:
Slc6a3

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 55 10 6 7
Binding ≤ 1μM 55 10 6 7

Reactome Network (2)

Reactome ID Description Species
REACT_231512 Dopamine clearance from the synaptic cleft Mus musculus
REACT_253228 Na+/Cl- dependent neurotransmitter transporters Mus musculus
Uniprot Swissprot Chembl Description Number Shared
SC6A2_MOUSE O55192 CHEMBL2370 Norepinephrine Transporter, Mouse 51
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
SC6A3_BOVIN P27922 CHEMBL2986 Dopamine Transporter, Bovin 51 1 1 1
SC6A3_HUMAN Q01959 CHEMBL238 Dopamine Transporter, Human 2,208 143 41 50
SC6A3_MACFA Q9GJT6 CHEMBL5032 Dopamine Transporter, Macfa 25 0 0 0
SC6A3_RAT P23977 CHEMBL338 Dopamine Transporter, Rat 2,890 133 48 52
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
SC6A1_MOUSE P31648 CHEMBL5445 GABA Transporter 1, Mouse 23 5 2 1
SC6A2_MOUSE O55192 CHEMBL2370 Norepinephrine Transporter, Mouse 52 9 5 6
SC6A4_MOUSE Q60857 CHEMBL4642 Serotonin Transporter, Mouse 63 5 4 4
SC6A9_MOUSE P28571 CHEMBL1075303 Sodium- And Chloride-dependent Glycine Transporter 1, Mouse 6 0 0 0

Clustered By Gene (0)

Clustered By Organism (2)

Code Description Substances Purchasable Natural In Man
SC6A3-1-E Dopamine Transporter (cluster #1 Of 3), Eukaryotic 4,670 193 44 54
SC6A3-2-E Dopamine Transporter (cluster #2 Of 3), Eukaryotic 280 40 20 13
SC6A3-3-E Dopamine Transporter (cluster #3 Of 3), Eukaryotic 241 38 15 21
Uniprot Swissprot Chembl Description Number Shared
SC6A2_MOUSE O55192 CHEMBL2370 Norepinephrine Transporter, Mouse 51
Q9WTR4_RAT Q9WTR4 CHEMBL304 Norepinephrine Transporter, Rat 18
SC6A4_RAT P31652 CHEMBL313 Serotonin Transporter, Rat 18
SC6A3_RAT P23977 CHEMBL338 Dopamine Transporter, Rat 17
SC6A2_HUMAN P23975 CHEMBL222 Norepinephrine Transporter, Human 9
SC6A4_HUMAN P31645 CHEMBL228 Serotonin Transporter, Human 9
Z104304 Z104304 CHEMBL1907610 Adrenergic Receptor Alpha-1 7
SC6A3_HUMAN Q01959 CHEMBL238 Dopamine Transporter, Human 6
5HT1A_RAT P19327 CHEMBL273 Serotonin 1a (5-HT1a) Receptor, Rat 5
5HT1B_RAT P28564 CHEMBL3459 Serotonin 1b (5-HT1b) Receptor, Rat 5
5HT1D_RAT P28565 CHEMBL5450 Serotonin 1d (5-HT1d) Receptor, Rat 5
5HT1F_RAT P30940 CHEMBL4646 Serotonin 1f (5-HT1f) Receptor, Rat 5
ADA2A_RAT P22909 CHEMBL327 Alpha-2a Adrenergic Receptor, Rat 5
ADA2B_RAT P19328 CHEMBL266 Alpha-2b Adrenergic Receptor, Rat 5
ADA2C_RAT P22086 CHEMBL314 Alpha-2c Adrenergic Receptor, Rat 5
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 5
Q63380_RAT Q63380 CHEMBL6184 Transporter, Rat 5
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 4
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 4
5HT2A_RAT P14842 CHEMBL322 Serotonin 2a (5-HT2a) Receptor, Rat 3
5HT2B_RAT P30994 CHEMBL323 Serotonin 2b (5-HT2b) Receptor, Rat 3
5HT2C_RAT P08909 CHEMBL324 Serotonin 2c (5-HT2c) Receptor, Rat 3
ACES_HUMAN P22303 CHEMBL220 Acetylcholinesterase, Human 2
HRH3_HUMAN Q9Y5N1 CHEMBL264 Histamine H3 Receptor, Human 2
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 1
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 1
5HT2C_MOUSE P34968 CHEMBL3006 Serotonin 2c (5-HT2c) Receptor, Mouse 1
5HT4R_RAT Q62758 CHEMBL4317 Serotonin 4 (5-HT4) Receptor, Rat 1
5HT5A_RAT P35364 CHEMBL4655 Serotonin 5a (5-HT5a) Receptor, Rat 1
5HT5B_RAT P35365 CHEMBL2619 Serotonin 5b (5-HT5b) Receptor, Rat 1
5HT6R_RAT P31388 CHEMBL3372 Serotonin 6 (5-HT6) Receptor, Rat 1
5HT7R_RAT P32305 CHEMBL3223 Serotonin 7 (5-HT7) Receptor, Rat 1
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 1
ACM5_RAT P08911 CHEMBL277 Muscarinic Acetylcholine Receptor M5, Rat 1
ADA1A_RAT P43140 CHEMBL319 Alpha-1a Adrenergic Receptor, Rat 1
ADA1B_RAT P15823 CHEMBL315 Alpha-1b Adrenergic Receptor, Rat 1
ADA1D_RAT P23944 CHEMBL326 Alpha-1d Adrenergic Receptor, Rat 1
ADCY1_HUMAN Q08828 CHEMBL2899 Brain Adenylate Cyclase 1, Human 1
ADCY2_HUMAN Q08462 CHEMBL3760 Adenylate Cyclase Type II, Human 1
ADCY8_HUMAN P40145 CHEMBL2960 Adenylate Cyclase Type VIII, Human 1
ADRB1_RAT P18090 CHEMBL3252 Beta-1 Adrenergic Receptor, Rat 1
ADRB2_RAT P10608 CHEMBL3754 Beta-2 Adrenergic Receptor, Rat 1
ADRB3_RAT P26255 CHEMBL4031 Beta-3 Adrenergic Receptor, Rat 1
DRD1_RAT P18901 CHEMBL265 Dopamine D1 Receptor, Rat 1
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 1
DRD2_MOUSE P61168 CHEMBL3427 Dopamine D2 Receptor, Mouse 1
DRD3_RAT P19020 CHEMBL3138 Dopamine D3 Receptor, Rat 1
DRD4_RAT P30729 CHEMBL3361 Dopamine D4 Receptor, Rat 1
DRD5_RAT P25115 CHEMBL2281 Dopamine D5 Receptor, Rat 1
HRH1_RAT P31390 CHEMBL4701 Histamine H1 Receptor, Rat 1
HRH2_RAT P25102 CHEMBL4654 Histamine H2 Receptor, Rat 1
HRH3_RAT Q9QYN8 CHEMBL4124 Histamine H3 Receptor, Rat 1
HRH4_RAT Q91ZY1 CHEMBL4468 Histamine H4 Receptor, Rat 1
NORA_STAAU P0A0J7 CHEMBL5114 Quinolone Resistance Protein NorA, Staau 1
PRIO_HUMAN P04156 CHEMBL4869 Prion Protein, Human 1
SC6A4_MOUSE Q60857 CHEMBL4642 Serotonin Transporter, Mouse 1
SCN1A_HUMAN P35498 CHEMBL1845 Sodium Channel Protein Type I Alpha Subunit, Human 1
SCN2A_HUMAN Q99250 CHEMBL4187 Sodium Channel Protein Type II Alpha Subunit, Human 1
SCN3A_HUMAN Q9NY46 CHEMBL5163 Sodium Channel Protein Type III Alpha Subunit, Human 1
SCN8A_HUMAN Q9UQD0 CHEMBL5202 Sodium Channel Protein Type VIII Alpha Subunit, Human 1
Z104303 Z104303 CHEMBL1907609 Muscarinic Acetylcholine Receptor 1