UCSF

Serotonin 6 (5-HT6) Receptor, Rat (14 Compounds)

Swissprot:
5HT6R_RAT
Stitch:
5HT6R_RAT
UniProt:
P31388
ChEMBL:
CHEMBL3372
Reactome:
REACT_246814
REACT_246144
PDB:
Htr6

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 14 11 9 10
Binding ≤ 1μM 11 8 6 7

Reactome Network (2)

Reactome ID Description Species
REACT_246814 G alpha (s) signalling events Rattus norvegicus
REACT_246144 Serotonin receptors Rattus norvegicus
Uniprot Swissprot Chembl Description Number Shared
5HT7R_RAT P32305 CHEMBL3223 Serotonin 7 (5-HT7) Receptor, Rat 13
ADRB1_RAT P18090 CHEMBL3252 Beta-1 Adrenergic Receptor, Rat 5
ADRB3_RAT P26255 CHEMBL4031 Beta-3 Adrenergic Receptor, Rat 5

Serotonin receptors

Uniprot Swissprot Chembl Description Number Shared
5HT1B_RAT P28564 CHEMBL3459 Serotonin 1b (5-HT1b) Receptor, Rat 13
5HT1D_RAT P28565 CHEMBL5450 Serotonin 1d (5-HT1d) Receptor, Rat 13
5HT2A_RAT P14842 CHEMBL322 Serotonin 2a (5-HT2a) Receptor, Rat 13
5HT5A_RAT P35364 CHEMBL4655 Serotonin 5a (5-HT5a) Receptor, Rat 12
5HT7R_RAT P32305 CHEMBL3223 Serotonin 7 (5-HT7) Receptor, Rat 13
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
5HT6R_HUMAN P50406 CHEMBL3371 Serotonin 6 (5-HT6) Receptor, Human 1,538 114 33 26

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
5HT6R-1-E Serotonin 6 (5-HT6) Receptor (cluster #1 Of 2), Eukaryotic 283 71 26 20
5HT6R-2-E Serotonin 6 (5-HT6) Receptor (cluster #2 Of 2), Eukaryotic 1,274 53 16 15
Uniprot Swissprot Chembl Description Number Shared
5HT1A_RAT P19327 CHEMBL273 Serotonin 1a (5-HT1a) Receptor, Rat 13
5HT1B_RAT P28564 CHEMBL3459 Serotonin 1b (5-HT1b) Receptor, Rat 13
5HT1D_RAT P28565 CHEMBL5450 Serotonin 1d (5-HT1d) Receptor, Rat 13
5HT2A_RAT P14842 CHEMBL322 Serotonin 2a (5-HT2a) Receptor, Rat 13
5HT2C_RAT P08909 CHEMBL324 Serotonin 2c (5-HT2c) Receptor, Rat 13
5HT4R_RAT Q62758 CHEMBL4317 Serotonin 4 (5-HT4) Receptor, Rat 13
5HT7R_RAT P32305 CHEMBL3223 Serotonin 7 (5-HT7) Receptor, Rat 13
5HT1F_RAT P30940 CHEMBL4646 Serotonin 1f (5-HT1f) Receptor, Rat 12
5HT2B_RAT P30994 CHEMBL323 Serotonin 2b (5-HT2b) Receptor, Rat 12
5HT5A_RAT P35364 CHEMBL4655 Serotonin 5a (5-HT5a) Receptor, Rat 12
5HT5B_RAT P35365 CHEMBL2619 Serotonin 5b (5-HT5b) Receptor, Rat 12
ADA2A_RAT P22909 CHEMBL327 Alpha-2a Adrenergic Receptor, Rat 10
ADA2B_RAT P19328 CHEMBL266 Alpha-2b Adrenergic Receptor, Rat 10
ADA2C_RAT P22086 CHEMBL314 Alpha-2c Adrenergic Receptor, Rat 10
Z104304 Z104304 CHEMBL1907610 Adrenergic Receptor Alpha-1 7
ADA1A_RAT P43140 CHEMBL319 Alpha-1a Adrenergic Receptor, Rat 5
ADA1B_RAT P15823 CHEMBL315 Alpha-1b Adrenergic Receptor, Rat 5
ADA1D_RAT P23944 CHEMBL326 Alpha-1d Adrenergic Receptor, Rat 5
ADCY1_HUMAN Q08828 CHEMBL2899 Brain Adenylate Cyclase 1, Human 5
ADCY2_HUMAN Q08462 CHEMBL3760 Adenylate Cyclase Type II, Human 5
ADCY8_HUMAN P40145 CHEMBL2960 Adenylate Cyclase Type VIII, Human 5
ADRB1_RAT P18090 CHEMBL3252 Beta-1 Adrenergic Receptor, Rat 5
ADRB2_RAT P10608 CHEMBL3754 Beta-2 Adrenergic Receptor, Rat 5
ADRB3_RAT P26255 CHEMBL4031 Beta-3 Adrenergic Receptor, Rat 5
DRD1_BOVIN Q95136 CHEMBL2967 Dopamine D1 Receptor, Bovin 5
DRD2_BOVIN P20288 CHEMBL3998 Dopamine D2 Receptor, Bovin 5
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 5
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 5
HRH1_RAT P31390 CHEMBL4701 Histamine H1 Receptor, Rat 5
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 5
SCN1A_HUMAN P35498 CHEMBL1845 Sodium Channel Protein Type I Alpha Subunit, Human 5
SCN2A_HUMAN Q99250 CHEMBL4187 Sodium Channel Protein Type II Alpha Subunit, Human 5
SCN3A_HUMAN Q9NY46 CHEMBL5163 Sodium Channel Protein Type III Alpha Subunit, Human 5
SCN8A_HUMAN Q9UQD0 CHEMBL5202 Sodium Channel Protein Type VIII Alpha Subunit, Human 5
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 4
DRD3_RAT P19020 CHEMBL3138 Dopamine D3 Receptor, Rat 4
DRD4_RAT P30729 CHEMBL3361 Dopamine D4 Receptor, Rat 4
SC6A4_RAT P31652 CHEMBL313 Serotonin Transporter, Rat 4
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 3
5HT3A_RAT P35563 CHEMBL2411 Serotonin 3a (5-HT3a) Receptor, Rat 3
5HT3B_RAT Q9JJ16 CHEMBL3458 Serotonin 3b (5-HT3b) Receptor, Rat 3
DRD1_HUMAN P21728 CHEMBL2056 Dopamine D1 Receptor, Human 3
DRD1_RAT P18901 CHEMBL265 Dopamine D1 Receptor, Rat 3
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 3
DRD5_RAT P25115 CHEMBL2281 Dopamine D5 Receptor, Rat 3
Q9WTR4_RAT Q9WTR4 CHEMBL304 Norepinephrine Transporter, Rat 3
SC6A2_HUMAN P23975 CHEMBL222 Norepinephrine Transporter, Human 3
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 3
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 2
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 2
ACM5_RAT P08911 CHEMBL277 Muscarinic Acetylcholine Receptor M5, Rat 2
ADA1A_HUMAN P35348 CHEMBL229 Alpha-1a Adrenergic Receptor, Human 2
ADA2A_HUMAN P08913 CHEMBL1867 Alpha-2a Adrenergic Receptor, Human 2
DRD5_HUMAN P21918 CHEMBL1850 Dopamine D5 Receptor, Human 2
HRH1_HUMAN P35367 CHEMBL231 Histamine H1 Receptor, Human 2
SC6A4_HUMAN P31645 CHEMBL228 Serotonin Transporter, Human 2
Z104303 Z104303 CHEMBL1907609 Muscarinic Acetylcholine Receptor 2
5HT2C_MOUSE P34968 CHEMBL3006 Serotonin 2c (5-HT2c) Receptor, Mouse 1
5HT6R_HUMAN P50406 CHEMBL3371 Serotonin 6 (5-HT6) Receptor, Human 1
5HT7R_HUMAN P34969 CHEMBL3155 Serotonin 7 (5-HT7) Receptor, Human 1
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 1
ACM1_RAT P08482 CHEMBL276 Muscarinic Acetylcholine Receptor M1, Rat 1
ACM2_RAT P10980 CHEMBL309 Muscarinic Acetylcholine Receptor M2, Rat 1
ACM3_RAT P08483 CHEMBL320 Muscarinic Acetylcholine Receptor M3, Rat 1
ADA1A_BOVIN P18130 CHEMBL4892 Alpha-1a Adrenergic Receptor, Bovin 1
ADA1B_HUMAN P35368 CHEMBL232 Alpha-1b Adrenergic Receptor, Human 1
ADA1D_HUMAN P25100 CHEMBL223 Alpha-1d Adrenergic Receptor, Human 1
ADA2A_BOVIN Q28838 CHEMBL4744 Alpha-2a Adrenergic Receptor, Bovin 1
ADA2B_HUMAN P18089 CHEMBL1942 Alpha-2b Adrenergic Receptor, Human 1
ADA2C_HUMAN P18825 CHEMBL1916 Alpha-2c Adrenergic Receptor, Human 1
CHLE_HUMAN P06276 CHEMBL1914 Butyrylcholinesterase, Human 1
DRD1_MOUSE Q61616 CHEMBL3071 Dopamine D1 Receptor, Mouse 1
DRD2_MOUSE P61168 CHEMBL3427 Dopamine D2 Receptor, Mouse 1
HRH1_CAVPO P31389 CHEMBL3943 Histamine H1 Receptor, Guinea Pig 1
HRH2_RAT P25102 CHEMBL4654 Histamine H2 Receptor, Rat 1
HRH3_RAT Q9QYN8 CHEMBL4124 Histamine H3 Receptor, Rat 1
HRH4_RAT Q91ZY1 CHEMBL4468 Histamine H4 Receptor, Rat 1
OPRD_RAT P33533 CHEMBL269 Delta Opioid Receptor, Rat 1
OPRK_RAT P34975 CHEMBL3614 Kappa Opioid Receptor, Rat 1
OPRM_RAT P33535 CHEMBL270 Mu Opioid Receptor, Rat 1
PRIO_HUMAN P04156 CHEMBL4869 Prion Protein, Human 1
Q63380_RAT Q63380 CHEMBL6184 Transporter, Rat 1
SC6A2_MOUSE O55192 CHEMBL2370 Norepinephrine Transporter, Mouse 1
SC6A3_HUMAN Q01959 CHEMBL238 Dopamine Transporter, Human 1
SC6A3_MOUSE Q61327 CHEMBL2799 Dopamine Transporter, Mouse 1
SC6A3_RAT P23977 CHEMBL338 Dopamine Transporter, Rat 1
SC6A4_MOUSE Q60857 CHEMBL4642 Serotonin Transporter, Mouse 1
SGMR1_RAT Q9R0C9 CHEMBL3602 Sigma Opioid Receptor, Rat 1
TYTR_TRYCR P28593 CHEMBL5131 Trypanothione Reductase, Trycr 1