ZINC 12

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Quick Search ZINC ID or SMILES

Names
Compounds (93)
Reactome (0)
Related By:
Pathway (0)
Organism (2)
Gene (2)
Org. Clust. (1)
ChEMBL (88)
Rings (8)

Histamine H1 Receptor, Guinea Pig (93 Compounds)

Swissprot:: HRH1_CAVPO
Stitch:: HRH1_CAVPO
UniProt:: P31389
ChEMBL:: CHEMBL3943
PDB:: HRH1

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	93	7	6	6
Binding ≤ 1μM	92	7	6	6
Functional ≤ 10μM	71	8	6	6

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
HRH1_HUMAN	P35367	CHEMBL231	Histamine H1 Receptor, Human	529	66	50	47
HRH1_RAT	P31390	CHEMBL4701	Histamine H1 Receptor, Rat	166	23	21	22

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
HRH2_CAVPO	P47747	CHEMBL2882	Histamine H2 Receptor, Guinea Pig	16	4	4	4
HRH3_CAVPO	Q9JI35	CHEMBL5076	Histamine H3 Receptor, Guinea Pig	125	5	8	0

Clustered By Gene (0)

Clustered By Organism (1)

Code	Description	Substances	Purchasable	Natural	In Man
HRH1-1-E	Histamine H1 Receptor (cluster #1 Of 2), Eukaryotic	635	47	34	36
HRH1-2-E	Histamine H1 Receptor (cluster #2 Of 2), Eukaryotic	138	34	28	25

Uniprot	Swissprot	Chembl	Description	Number Shared
HRH2_HUMAN	P25021	CHEMBL1941	Histamine H2 Receptor, Human	46
Z104304	Z104304	CHEMBL1907610	Adrenergic Receptor Alpha-1	24
5HT2A_HUMAN	P28223	CHEMBL224	Serotonin 2a (5-HT2a) Receptor, Human	18
5HT2C_HUMAN	P28335	CHEMBL225	Serotonin 2c (5-HT2c) Receptor, Human	17
5HT2B_HUMAN	P41595	CHEMBL1833	Serotonin 2b (5-HT2b) Receptor, Human	12
5HT1A_RAT	P19327	CHEMBL273	Serotonin 1a (5-HT1a) Receptor, Rat	9
HRH1_HUMAN	P35367	CHEMBL231	Histamine H1 Receptor, Human	9
DRD2_RAT	P61169	CHEMBL339	Dopamine D2 Receptor, Rat	8
5HT2C_RAT	P08909	CHEMBL324	Serotonin 2c (5-HT2c) Receptor, Rat	7
ADA1D_HUMAN	P25100	CHEMBL223	Alpha-1d Adrenergic Receptor, Human	7
ADA2A_HUMAN	P08913	CHEMBL1867	Alpha-2a Adrenergic Receptor, Human	7
ADA2C_HUMAN	P18825	CHEMBL1916	Alpha-2c Adrenergic Receptor, Human	7
5HT2A_RAT	P14842	CHEMBL322	Serotonin 2a (5-HT2a) Receptor, Rat	6
ADA1A_HUMAN	P35348	CHEMBL229	Alpha-1a Adrenergic Receptor, Human	6
ADA1B_HUMAN	P35368	CHEMBL232	Alpha-1b Adrenergic Receptor, Human	6
ADA2B_HUMAN	P18089	CHEMBL1942	Alpha-2b Adrenergic Receptor, Human	6
5HT1D_HUMAN	P28221	CHEMBL1983	Serotonin 1d (5-HT1d) Receptor, Human	5
DRD2_HUMAN	P14416	CHEMBL217	Dopamine D2 Receptor, Human	5
5HT2A_BOVIN	Q75Z89	CHEMBL3446	Serotonin 2a (5-HT2a) Receptor, Bovin	4
5HT2B_RAT	P30994	CHEMBL323	Serotonin 2b (5-HT2b) Receptor, Rat	4
KCNH2_HUMAN	Q12809	CHEMBL240	HERG, Human	4
5HT1A_HUMAN	P08908	CHEMBL214	Serotonin 1a (5-HT1a) Receptor, Human	3
5HT1D_PIG	P79400	CHEMBL4105	Serotonin 1d (5-HT1d) Receptor, Pig	3
DRD1_RAT	P18901	CHEMBL265	Dopamine D1 Receptor, Rat	3
DRD3_HUMAN	P35462	CHEMBL234	Dopamine D3 Receptor, Human	3
DRD3_RAT	P19020	CHEMBL3138	Dopamine D3 Receptor, Rat	3
DRD4_HUMAN	P21917	CHEMBL219	Dopamine D4 Receptor, Human	3
HRH2_CAVPO	P47747	CHEMBL2882	Histamine H2 Receptor, Guinea Pig	3
Z50425	Z50425	CHEMBL364	Plasmodium Falciparum	3
5HT1B_HUMAN	P28222	CHEMBL1898	Serotonin 1b (5-HT1b) Receptor, Human	2
5HT1B_RAT	P28564	CHEMBL3459	Serotonin 1b (5-HT1b) Receptor, Rat	2
5HT1D_RAT	P28565	CHEMBL5450	Serotonin 1d (5-HT1d) Receptor, Rat	2
5HT1E_HUMAN	P28566	CHEMBL2182	Serotonin 1e (5-HT1e) Receptor, Human	2
5HT3A_RAT	P35563	CHEMBL2411	Serotonin 3a (5-HT3a) Receptor, Rat	2
5HT3B_RAT	Q9JJ16	CHEMBL3458	Serotonin 3b (5-HT3b) Receptor, Rat	2
5HT6R_HUMAN	P50406	CHEMBL3371	Serotonin 6 (5-HT6) Receptor, Human	2
5HT7R_HUMAN	P34969	CHEMBL3155	Serotonin 7 (5-HT7) Receptor, Human	2
5HT7R_RAT	P32305	CHEMBL3223	Serotonin 7 (5-HT7) Receptor, Rat	2
ADA1A_BOVIN	P18130	CHEMBL4892	Alpha-1a Adrenergic Receptor, Bovin	2
ADA2A_BOVIN	Q28838	CHEMBL4744	Alpha-2a Adrenergic Receptor, Bovin	2
DRD4_RAT	P30729	CHEMBL3361	Dopamine D4 Receptor, Rat	2
SC6A4_RAT	P31652	CHEMBL313	Serotonin Transporter, Rat	2
Z50597	Z50597	CHEMBL376	Rattus Norvegicus	2
5HT1A_MOUSE	Q64264	CHEMBL3737	Serotonin 1a (5-HT1a) Receptor, Mouse	1
5HT1F_HUMAN	P30939	CHEMBL1805	Serotonin 1f (5-HT1f) Receptor, Human	1
5HT1F_RAT	P30940	CHEMBL4646	Serotonin 1f (5-HT1f) Receptor, Rat	1
5HT3A_HUMAN	P46098	CHEMBL1899	Serotonin 3a (5-HT3a) Receptor, Human	1
5HT3A_MOUSE	P23979	CHEMBL4972	Serotonin 3a (5-HT3a) Receptor, Mouse	1
5HT3B_MOUSE	Q9JHJ5	CHEMBL3781	Serotonin 3b (5-HT3b) Receptor, Mouse	1
5HT4R_CAVPO	O70528	CHEMBL5017	Serotonin 4 (5-HT4) Receptor, Guinea Pig	1
5HT4R_HUMAN	Q13639	CHEMBL1875	Serotonin 4 (5-HT4) Receptor, Human	1
5HT4R_RAT	Q62758	CHEMBL4317	Serotonin 4 (5-HT4) Receptor, Rat	1
5HT5A_HUMAN	P47898	CHEMBL3426	Serotonin 5a (5-HT5a) Receptor, Human	1
5HT6R_RAT	P31388	CHEMBL3372	Serotonin 6 (5-HT6) Receptor, Rat	1
AA3R_HUMAN	P33765	CHEMBL256	Adenosine A3 Receptor, Human	1
ACM2_HUMAN	P08172	CHEMBL211	Muscarinic Acetylcholine Receptor M2, Human	1
ACM3_HUMAN	P20309	CHEMBL245	Muscarinic Acetylcholine Receptor M3, Human	1
ACM4_HUMAN	P08173	CHEMBL1821	Muscarinic Acetylcholine Receptor M4, Human	1
ACM5_HUMAN	P08912	CHEMBL2035	Muscarinic Acetylcholine Receptor M5, Human	1
ACM5_RAT	P08911	CHEMBL277	Muscarinic Acetylcholine Receptor M5, Rat	1
ADA1A_RAT	P43140	CHEMBL319	Alpha-1a Adrenergic Receptor, Rat	1
ADA1B_RAT	P15823	CHEMBL315	Alpha-1b Adrenergic Receptor, Rat	1
ADA1D_RAT	P23944	CHEMBL326	Alpha-1d Adrenergic Receptor, Rat	1
ADA2A_RAT	P22909	CHEMBL327	Alpha-2a Adrenergic Receptor, Rat	1
ADA2B_BOVIN	O77700	CHEMBL3523	Alpha-2b Adrenergic Receptor, Bovin	1
ADA2B_RAT	P19328	CHEMBL266	Alpha-2b Adrenergic Receptor, Rat	1
ADA2C_RAT	P22086	CHEMBL314	Alpha-2c Adrenergic Receptor, Rat	1
ADCY1_HUMAN	Q08828	CHEMBL2899	Brain Adenylate Cyclase 1, Human	1
ADCY2_HUMAN	Q08462	CHEMBL3760	Adenylate Cyclase Type II, Human	1
ADCY8_HUMAN	P40145	CHEMBL2960	Adenylate Cyclase Type VIII, Human	1
DRD5_HUMAN	P21918	CHEMBL1850	Dopamine D5 Receptor, Human	1
HRH1_RAT	P31390	CHEMBL4701	Histamine H1 Receptor, Rat	1
HRH2_RAT	P25102	CHEMBL4654	Histamine H2 Receptor, Rat	1
HRH3_CAVPO	Q9JI35	CHEMBL5076	Histamine H3 Receptor, Guinea Pig	1
HRH3_HUMAN	Q9Y5N1	CHEMBL264	Histamine H3 Receptor, Human	1
HRH3_RAT	Q9QYN8	CHEMBL4124	Histamine H3 Receptor, Rat	1
HRH4_RAT	Q91ZY1	CHEMBL4468	Histamine H4 Receptor, Rat	1
Q9WTR4_RAT	Q9WTR4	CHEMBL304	Norepinephrine Transporter, Rat	1
SC6A2_HUMAN	P23975	CHEMBL222	Norepinephrine Transporter, Human	1
SC6A3_HUMAN	Q01959	CHEMBL238	Dopamine Transporter, Human	1
SC6A4_HUMAN	P31645	CHEMBL228	Serotonin Transporter, Human	1
SCN1A_HUMAN	P35498	CHEMBL1845	Sodium Channel Protein Type I Alpha Subunit, Human	1
SCN2A_HUMAN	Q99250	CHEMBL4187	Sodium Channel Protein Type II Alpha Subunit, Human	1
SCN3A_HUMAN	Q9NY46	CHEMBL5163	Sodium Channel Protein Type III Alpha Subunit, Human	1
SCN8A_HUMAN	Q9UQD0	CHEMBL5202	Sodium Channel Protein Type VIII Alpha Subunit, Human	1
SGMR1_RAT	Q9R0C9	CHEMBL3602	Sigma Opioid Receptor, Rat	1
Z50512	Z50512	CHEMBL369	Cavia Porcellus	1
Z80362	Z80362	CHEMBL389	P388 (Lymphoma Cells)	1