UCSF

Serotonin 1a (5-HT1a) Receptor, Mouse (59 Compounds)

Swissprot:
5HT1A_MOUSE
Stitch:
5HT1A_MOUSE
UniProt:
Q64264
ChEMBL:
CHEMBL3737
Reactome:
REACT_250376
REACT_232980
PDB:
Htr1a

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 59 11 7 7
Binding ≤ 1μM 53 10 6 6

Reactome Network (2)

Reactome ID Description Species
REACT_250376 G alpha (i) signalling events Mus musculus
REACT_232980 Serotonin receptors Mus musculus
Uniprot Swissprot Chembl Description Number Shared
5HT5A_MOUSE P30966 CHEMBL3597 Serotonin 5a (5-HT5a) Receptor, Mouse 1
DRD2_MOUSE P61168 CHEMBL3427 Dopamine D2 Receptor, Mouse 22

Serotonin receptors

Uniprot Swissprot Chembl Description Number Shared
5HT2A_MOUSE P35363 CHEMBL5377 Serotonin 2a (5-HT2a) Receptor, Mouse 21
5HT2B_MOUSE Q02152 CHEMBL2583 Serotonin 2b (5-HT2b) Receptor, Mouse 21
5HT2C_MOUSE P34968 CHEMBL3006 Serotonin 2c (5-HT2c) Receptor, Mouse 21
5HT4R_MOUSE P97288 CHEMBL2183 Serotonin 4 (5-HT4) Receptor, Mouse 1
5HT5A_MOUSE P30966 CHEMBL3597 Serotonin 5a (5-HT5a) Receptor, Mouse 1
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 2,609 146 55 49
5HT1A_RAT P19327 CHEMBL273 Serotonin 1a (5-HT1a) Receptor, Rat 3,911 396 74 82

Clustered By Gene (0)

Clustered By Organism (3)

Code Description Substances Purchasable Natural In Man
5HT1A-1-E Serotonin 1a (5-HT1a) Receptor (cluster #1 Of 4), Eukaryotic 5,580 378 83 90
5HT1A-2-E Serotonin 1a (5-HT1a) Receptor (cluster #2 Of 4), Eukaryotic 23 2 0 0
5HT1A-3-E Serotonin 1a (5-HT1a) Receptor (cluster #3 Of 4), Eukaryotic 315 63 12 11
5HT1A-4-E Serotonin 1a (5-HT1a) Receptor (cluster #4 Of 4), Eukaryotic 686 64 14 14
Uniprot Swissprot Chembl Description Number Shared
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 28
DRD2_MOUSE P61168 CHEMBL3427 Dopamine D2 Receptor, Mouse 22
5HT1A_RAT P19327 CHEMBL273 Serotonin 1a (5-HT1a) Receptor, Rat 21
5HT2A_MOUSE P35363 CHEMBL5377 Serotonin 2a (5-HT2a) Receptor, Mouse 21
5HT2B_MOUSE Q02152 CHEMBL2583 Serotonin 2b (5-HT2b) Receptor, Mouse 21
5HT2C_MOUSE P34968 CHEMBL3006 Serotonin 2c (5-HT2c) Receptor, Mouse 21
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 19
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 15
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 13
5HT1D_HUMAN P28221 CHEMBL1983 Serotonin 1d (5-HT1d) Receptor, Human 13
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 10
ADA2A_RAT P22909 CHEMBL327 Alpha-2a Adrenergic Receptor, Rat 9
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 9
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 8
5HT7R_RAT P32305 CHEMBL3223 Serotonin 7 (5-HT7) Receptor, Rat 8
5HT2A_BOVIN Q75Z89 CHEMBL3446 Serotonin 2a (5-HT2a) Receptor, Bovin 7
5HT1B_HUMAN P28222 CHEMBL1898 Serotonin 1b (5-HT1b) Receptor, Human 6
5HT2A_RAT P14842 CHEMBL322 Serotonin 2a (5-HT2a) Receptor, Rat 6
5HT2B_RAT P30994 CHEMBL323 Serotonin 2b (5-HT2b) Receptor, Rat 6
5HT2C_RAT P08909 CHEMBL324 Serotonin 2c (5-HT2c) Receptor, Rat 6
5HT7R_HUMAN P34969 CHEMBL3155 Serotonin 7 (5-HT7) Receptor, Human 6
5HT1B_RAT P28564 CHEMBL3459 Serotonin 1b (5-HT1b) Receptor, Rat 5
5HT1D_RAT P28565 CHEMBL5450 Serotonin 1d (5-HT1d) Receptor, Rat 5
5HT2B_HUMAN P41595 CHEMBL1833 Serotonin 2b (5-HT2b) Receptor, Human 5
ADA1A_HUMAN P35348 CHEMBL229 Alpha-1a Adrenergic Receptor, Human 5
ADA1B_HUMAN P35368 CHEMBL232 Alpha-1b Adrenergic Receptor, Human 5
ADA1D_HUMAN P25100 CHEMBL223 Alpha-1d Adrenergic Receptor, Human 5
DRD3_RAT P19020 CHEMBL3138 Dopamine D3 Receptor, Rat 5
Z104304 Z104304 CHEMBL1907610 Adrenergic Receptor Alpha-1 5
5HT1F_RAT P30940 CHEMBL4646 Serotonin 1f (5-HT1f) Receptor, Rat 4
5HT5A_HUMAN P47898 CHEMBL3426 Serotonin 5a (5-HT5a) Receptor, Human 4
HRH1_HUMAN P35367 CHEMBL231 Histamine H1 Receptor, Human 4
SGMR1_HUMAN Q99720 CHEMBL287 Sigma Opioid Receptor, Human 4
5HT1E_HUMAN P28566 CHEMBL2182 Serotonin 1e (5-HT1e) Receptor, Human 3
5HT3A_RAT P35563 CHEMBL2411 Serotonin 3a (5-HT3a) Receptor, Rat 3
5HT3B_RAT Q9JJ16 CHEMBL3458 Serotonin 3b (5-HT3b) Receptor, Rat 3
5HT6R_HUMAN P50406 CHEMBL3371 Serotonin 6 (5-HT6) Receptor, Human 3
AA2BR_RAT P29276 CHEMBL2592 Adenosine A2b Receptor, Rat 3
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 3
ADA1A_BOVIN P18130 CHEMBL4892 Alpha-1a Adrenergic Receptor, Bovin 3
ADA1A_RAT P43140 CHEMBL319 Alpha-1a Adrenergic Receptor, Rat 3
ADA2A_HUMAN P08913 CHEMBL1867 Alpha-2a Adrenergic Receptor, Human 3
ADA2B_HUMAN P18089 CHEMBL1942 Alpha-2b Adrenergic Receptor, Human 3
ADA2C_HUMAN P18825 CHEMBL1916 Alpha-2c Adrenergic Receptor, Human 3
DRD1_HUMAN P21728 CHEMBL2056 Dopamine D1 Receptor, Human 3
DRD2_BOVIN P20288 CHEMBL3998 Dopamine D2 Receptor, Bovin 3
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 3
5HT1D_PIG P79400 CHEMBL4105 Serotonin 1d (5-HT1d) Receptor, Pig 2
5HT1F_HUMAN P30939 CHEMBL1805 Serotonin 1f (5-HT1f) Receptor, Human 2
5HT3A_HUMAN P46098 CHEMBL1899 Serotonin 3a (5-HT3a) Receptor, Human 2
5HT3A_MOUSE P23979 CHEMBL4972 Serotonin 3a (5-HT3a) Receptor, Mouse 2
5HT4R_HUMAN Q13639 CHEMBL1875 Serotonin 4 (5-HT4) Receptor, Human 2
ACM1_HUMAN P11229 CHEMBL216 Muscarinic Acetylcholine Receptor M1, Human 2
ACM2_HUMAN P08172 CHEMBL211 Muscarinic Acetylcholine Receptor M2, Human 2
ACM3_HUMAN P20309 CHEMBL245 Muscarinic Acetylcholine Receptor M3, Human 2
ACM4_HUMAN P08173 CHEMBL1821 Muscarinic Acetylcholine Receptor M4, Human 2
ACM5_HUMAN P08912 CHEMBL2035 Muscarinic Acetylcholine Receptor M5, Human 2
ADA1D_RAT P23944 CHEMBL326 Alpha-1d Adrenergic Receptor, Rat 2
ADA2A_BOVIN Q28838 CHEMBL4744 Alpha-2a Adrenergic Receptor, Bovin 2
ADA2B_RAT P19328 CHEMBL266 Alpha-2b Adrenergic Receptor, Rat 2
ADA2C_RAT P22086 CHEMBL314 Alpha-2c Adrenergic Receptor, Rat 2
DRD1_RAT P18901 CHEMBL265 Dopamine D1 Receptor, Rat 2
HRH1_RAT P31390 CHEMBL4701 Histamine H1 Receptor, Rat 2
SC6A4_HUMAN P31645 CHEMBL228 Serotonin Transporter, Human 2
5HT3B_HUMAN O95264 CHEMBL3895 Serotonin 3b (5-HT3b) Receptor, Human 1
5HT3B_MOUSE Q9JHJ5 CHEMBL3781 Serotonin 3b (5-HT3b) Receptor, Mouse 1
5HT3C_HUMAN Q8WXA8 CHEMBL4795 Serotonin 3c (5-HT3c) Receptor, Human 1
5HT3D_HUMAN Q70Z44 CHEMBL4673 Serotonin 3d (5-HT3d) Receptor, Human 1
5HT3E_HUMAN A5X5Y0 CHEMBL3812 Serotonin 3e (5-HT3e) Receptor, Human 1
5HT4R_CAVPO O70528 CHEMBL5017 Serotonin 4 (5-HT4) Receptor, Guinea Pig 1
5HT4R_MOUSE P97288 CHEMBL2183 Serotonin 4 (5-HT4) Receptor, Mouse 1
5HT4R_RAT Q62758 CHEMBL4317 Serotonin 4 (5-HT4) Receptor, Rat 1
5HT5A_MOUSE P30966 CHEMBL3597 Serotonin 5a (5-HT5a) Receptor, Mouse 1
ACM1_RAT P08482 CHEMBL276 Muscarinic Acetylcholine Receptor M1, Rat 1
ACM2_RAT P10980 CHEMBL309 Muscarinic Acetylcholine Receptor M2, Rat 1
ACM3_RAT P08483 CHEMBL320 Muscarinic Acetylcholine Receptor M3, Rat 1
ACM4_RAT P08485 CHEMBL317 Muscarinic Acetylcholine Receptor M4, Rat 1
ADA1B_RAT P15823 CHEMBL315 Alpha-1b Adrenergic Receptor, Rat 1
DRD1_BOVIN Q95136 CHEMBL2967 Dopamine D1 Receptor, Bovin 1
DRD1_MOUSE Q61616 CHEMBL3071 Dopamine D1 Receptor, Mouse 1
DRD1_PIG P50130 CHEMBL5067 Dopamine D1 Receptor, Pig 1
DRD2_CHLAE P52702 CHEMBL5456 Dopamine D2 Receptor, Chlae 1
DRD4_RAT P30729 CHEMBL3361 Dopamine D4 Receptor, Rat 1
DRD5_HUMAN P21918 CHEMBL1850 Dopamine D5 Receptor, Human 1
DRD5_RAT P25115 CHEMBL2281 Dopamine D5 Receptor, Rat 1
HRH1_CAVPO P31389 CHEMBL3943 Histamine H1 Receptor, Guinea Pig 1
HRH2_RAT P25102 CHEMBL4654 Histamine H2 Receptor, Rat 1
HRH3_RAT Q9QYN8 CHEMBL4124 Histamine H3 Receptor, Rat 1
HRH4_HUMAN Q9H3N8 CHEMBL3759 Histamine H4 Receptor, Human 1
HRH4_RAT Q91ZY1 CHEMBL4468 Histamine H4 Receptor, Rat 1
NMD3A_HUMAN Q8TCU5 CHEMBL4787 Glutamate [NMDA] Receptor Subunit 3A, Human 1
NMD3A_RAT Q9R1M7 CHEMBL342 Glutamate [NMDA] Receptor Subunit 3A, Rat 1
NMD3B_HUMAN O60391 CHEMBL2913 Glutamate [NMDA] Receptor Subunit 3B, Human 1
NMD3B_RAT Q8VHN2 CHEMBL282 Glutamate [NMDA] Receptor Subunit 3B, Rat 1
NMDE1_HUMAN Q12879 CHEMBL1972 Glutamate [NMDA] Receptor Subunit Epsilon 1, Human 1
NMDE2_HUMAN Q13224 CHEMBL1904 Glutamate [NMDA] Receptor Subunit Epsilon 2, Human 1
NMDE2_RAT Q00960 CHEMBL311 Glutamate [NMDA] Receptor Subunit Epsilon 2, Rat 1
NMDE3_HUMAN Q14957 CHEMBL4109 Glutamate [NMDA] Receptor Subunit Epsilon 3, Human 1
NMDE4_HUMAN O15399 CHEMBL2591 Glutamate [NMDA] Receptor Subunit Epsilon 4, Human 1
NMDZ1_HUMAN Q05586 CHEMBL2015 Glutamate (NMDA) Receptor Subunit Zeta 1, Human 1
NMDZ1_RAT P35439 CHEMBL330 Glutamate (NMDA) Receptor Subunit Zeta 1, Rat 1
Q63380_RAT Q63380 CHEMBL6184 Transporter, Rat 1
Q9WTR4_RAT Q9WTR4 CHEMBL304 Norepinephrine Transporter, Rat 1
SC6A4_RAT P31652 CHEMBL313 Serotonin Transporter, Rat 1
SGMR1_RAT Q9R0C9 CHEMBL3602 Sigma Opioid Receptor, Rat 1
V1BR_RAT P48974 CHEMBL2659 Vasopressin V1b Receptor, Rat 1
Z104303 Z104303 CHEMBL1907609 Muscarinic Acetylcholine Receptor 1

Most Common Rings