ZINC 12

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Quick Search ZINC ID or SMILES

Names
Compounds (175)
Reactome (2)
Related By:
Pathway (27)
Organism (2)
Gene (0)
Org. Clust. (0)
ChEMBL (113)
Rings (14)

Serotonin 5a (5-HT5a) Receptor, Human (175 Compounds)

Swissprot:: 5HT5A_HUMAN
Stitch:: 5HT5A_HUMAN
UniProt:: P47898
ChEMBL:: CHEMBL3426
Reactome:: REACT_19231; REACT_17064
PDB:: HTR5A

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	175	23	9	5
Binding ≤ 1μM	143	17	6	5

Reactome ID	Description	Species
REACT_19231	G alpha (i) signalling events	Homo sapiens
REACT_17064	Serotonin receptors	Homo sapiens

Uniprot	Swissprot	Chembl	Description	Number Shared
5HT1A_HUMAN	P08908	CHEMBL214	Serotonin 1a (5-HT1a) Receptor, Human	74
5HT1B_HUMAN	P28222	CHEMBL1898	Serotonin 1b (5-HT1b) Receptor, Human	19
5HT1D_HUMAN	P28221	CHEMBL1983	Serotonin 1d (5-HT1d) Receptor, Human	62
5HT1E_HUMAN	P28566	CHEMBL2182	Serotonin 1e (5-HT1e) Receptor, Human	20
5HT1F_HUMAN	P30939	CHEMBL1805	Serotonin 1f (5-HT1f) Receptor, Human	7
AA3R_HUMAN	P33765	CHEMBL256	Adenosine A3 Receptor, Human	6
ACM2_HUMAN	P08172	CHEMBL211	Muscarinic Acetylcholine Receptor M2, Human	4
ACM4_HUMAN	P08173	CHEMBL1821	Muscarinic Acetylcholine Receptor M4, Human	4
ADA2A_HUMAN	P08913	CHEMBL1867	Alpha-2a Adrenergic Receptor, Human	9
ADA2B_HUMAN	P18089	CHEMBL1942	Alpha-2b Adrenergic Receptor, Human	8
ADA2C_HUMAN	P18825	CHEMBL1916	Alpha-2c Adrenergic Receptor, Human	11
DRD2_HUMAN	P14416	CHEMBL217	Dopamine D2 Receptor, Human	26
DRD3_HUMAN	P35462	CHEMBL234	Dopamine D3 Receptor, Human	22
DRD4_HUMAN	P21917	CHEMBL219	Dopamine D4 Receptor, Human	22
HRH3_HUMAN	Q9Y5N1	CHEMBL264	Histamine H3 Receptor, Human	4
HRH4_HUMAN	Q9H3N8	CHEMBL3759	Histamine H4 Receptor, Human	3
OPRD_HUMAN	P41143	CHEMBL236	Delta Opioid Receptor, Human	3
OPRK_HUMAN	P41145	CHEMBL237	Kappa Opioid Receptor, Human	3
OPRM_HUMAN	P35372	CHEMBL233	Mu Opioid Receptor, Human	7

Serotonin receptors

Uniprot	Swissprot	Chembl	Description	Number Shared
5HT1A_HUMAN	P08908	CHEMBL214	Serotonin 1a (5-HT1a) Receptor, Human	74
5HT1B_HUMAN	P28222	CHEMBL1898	Serotonin 1b (5-HT1b) Receptor, Human	19
5HT1D_HUMAN	P28221	CHEMBL1983	Serotonin 1d (5-HT1d) Receptor, Human	62
5HT1E_HUMAN	P28566	CHEMBL2182	Serotonin 1e (5-HT1e) Receptor, Human	20
5HT1F_HUMAN	P30939	CHEMBL1805	Serotonin 1f (5-HT1f) Receptor, Human	7
5HT2A_HUMAN	P28223	CHEMBL224	Serotonin 2a (5-HT2a) Receptor, Human	26
5HT2B_HUMAN	P41595	CHEMBL1833	Serotonin 2b (5-HT2b) Receptor, Human	27
5HT2C_HUMAN	P28335	CHEMBL225	Serotonin 2c (5-HT2c) Receptor, Human	62
5HT4R_HUMAN	Q13639	CHEMBL1875	Serotonin 4 (5-HT4) Receptor, Human	10
5HT6R_HUMAN	P50406	CHEMBL3371	Serotonin 6 (5-HT6) Receptor, Human	39
5HT7R_HUMAN	P34969	CHEMBL3155	Serotonin 7 (5-HT7) Receptor, Human	81

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
5HT5A_MOUSE	P30966	CHEMBL3597	Serotonin 5a (5-HT5a) Receptor, Mouse	38	7	3	1
5HT5A_RAT	P35364	CHEMBL4655	Serotonin 5a (5-HT5a) Receptor, Rat	34	9	8	8

Clustered By Gene (0)

Uniprot	Swissprot	Chembl	Description	Number Shared
5HT7R_HUMAN	P34969	CHEMBL3155	Serotonin 7 (5-HT7) Receptor, Human	81
5HT1A_HUMAN	P08908	CHEMBL214	Serotonin 1a (5-HT1a) Receptor, Human	74
5HT1D_HUMAN	P28221	CHEMBL1983	Serotonin 1d (5-HT1d) Receptor, Human	62
5HT2C_HUMAN	P28335	CHEMBL225	Serotonin 2c (5-HT2c) Receptor, Human	62
5HT2A_RAT	P14842	CHEMBL322	Serotonin 2a (5-HT2a) Receptor, Rat	40
5HT6R_HUMAN	P50406	CHEMBL3371	Serotonin 6 (5-HT6) Receptor, Human	39
5HT2C_RAT	P08909	CHEMBL324	Serotonin 2c (5-HT2c) Receptor, Rat	32
5HT2B_HUMAN	P41595	CHEMBL1833	Serotonin 2b (5-HT2b) Receptor, Human	27
5HT2A_HUMAN	P28223	CHEMBL224	Serotonin 2a (5-HT2a) Receptor, Human	26
DRD2_HUMAN	P14416	CHEMBL217	Dopamine D2 Receptor, Human	25
DRD3_HUMAN	P35462	CHEMBL234	Dopamine D3 Receptor, Human	22
DRD4_HUMAN	P21917	CHEMBL219	Dopamine D4 Receptor, Human	22
HRH1_HUMAN	P35367	CHEMBL231	Histamine H1 Receptor, Human	22
5HT1E_HUMAN	P28566	CHEMBL2182	Serotonin 1e (5-HT1e) Receptor, Human	20
5HT5A_MOUSE	P30966	CHEMBL3597	Serotonin 5a (5-HT5a) Receptor, Mouse	20
5HT1B_HUMAN	P28222	CHEMBL1898	Serotonin 1b (5-HT1b) Receptor, Human	19
DRD5_HUMAN	P21918	CHEMBL1850	Dopamine D5 Receptor, Human	17
5HT3A_HUMAN	P46098	CHEMBL1899	Serotonin 3a (5-HT3a) Receptor, Human	15
ADA1B_HUMAN	P35368	CHEMBL232	Alpha-1b Adrenergic Receptor, Human	15
ADA1A_HUMAN	P35348	CHEMBL229	Alpha-1a Adrenergic Receptor, Human	14
SC6A4_HUMAN	P31645	CHEMBL228	Serotonin Transporter, Human	13
5HT7R_RAT	P32305	CHEMBL3223	Serotonin 7 (5-HT7) Receptor, Rat	12
ADA1D_HUMAN	P25100	CHEMBL223	Alpha-1d Adrenergic Receptor, Human	12
DRD1_HUMAN	P21728	CHEMBL2056	Dopamine D1 Receptor, Human	12
ADA2C_HUMAN	P18825	CHEMBL1916	Alpha-2c Adrenergic Receptor, Human	11
5HT1A_RAT	P19327	CHEMBL273	Serotonin 1a (5-HT1a) Receptor, Rat	10
5HT4R_HUMAN	Q13639	CHEMBL1875	Serotonin 4 (5-HT4) Receptor, Human	10
ADRB1_HUMAN	P08588	CHEMBL213	Beta-1 Adrenergic Receptor, Human	10
ADRB2_HUMAN	P07550	CHEMBL210	Beta-2 Adrenergic Receptor, Human	10
HRH2_HUMAN	P25021	CHEMBL1941	Histamine H2 Receptor, Human	10
ADA2A_HUMAN	P08913	CHEMBL1867	Alpha-2a Adrenergic Receptor, Human	9
5HT1B_RAT	P28564	CHEMBL3459	Serotonin 1b (5-HT1b) Receptor, Rat	8
5HT2B_RAT	P30994	CHEMBL323	Serotonin 2b (5-HT2b) Receptor, Rat	8
5HT3B_HUMAN	O95264	CHEMBL3895	Serotonin 3b (5-HT3b) Receptor, Human	8
5HT3C_HUMAN	Q8WXA8	CHEMBL4795	Serotonin 3c (5-HT3c) Receptor, Human	8
5HT3D_HUMAN	Q70Z44	CHEMBL4673	Serotonin 3d (5-HT3d) Receptor, Human	8
5HT3E_HUMAN	A5X5Y0	CHEMBL3812	Serotonin 3e (5-HT3e) Receptor, Human	8
ADA2B_HUMAN	P18089	CHEMBL1942	Alpha-2b Adrenergic Receptor, Human	8
5HT1D_RAT	P28565	CHEMBL5450	Serotonin 1d (5-HT1d) Receptor, Rat	7
DRD1_MOUSE	Q61616	CHEMBL3071	Dopamine D1 Receptor, Mouse	7
DRD2_RAT	P61169	CHEMBL339	Dopamine D2 Receptor, Rat	7
OPRM_HUMAN	P35372	CHEMBL233	Mu Opioid Receptor, Human	7
SGMR1_HUMAN	Q99720	CHEMBL287	Sigma Opioid Receptor, Human	7
5HT1F_HUMAN	P30939	CHEMBL1805	Serotonin 1f (5-HT1f) Receptor, Human	6
5HT1F_RAT	P30940	CHEMBL4646	Serotonin 1f (5-HT1f) Receptor, Rat	6
AA3R_HUMAN	P33765	CHEMBL256	Adenosine A3 Receptor, Human	6
SC6A3_HUMAN	Q01959	CHEMBL238	Dopamine Transporter, Human	6
ADA2A_RAT	P22909	CHEMBL327	Alpha-2a Adrenergic Receptor, Rat	5
ADA2B_RAT	P19328	CHEMBL266	Alpha-2b Adrenergic Receptor, Rat	5
ADA2C_RAT	P22086	CHEMBL314	Alpha-2c Adrenergic Receptor, Rat	5
DRD2_BOVIN	P20288	CHEMBL3998	Dopamine D2 Receptor, Bovin	5
DRD3_RAT	P19020	CHEMBL3138	Dopamine D3 Receptor, Rat	5
5HT1A_MOUSE	Q64264	CHEMBL3737	Serotonin 1a (5-HT1a) Receptor, Mouse	4
5HT3A_RAT	P35563	CHEMBL2411	Serotonin 3a (5-HT3a) Receptor, Rat	4
5HT3B_RAT	Q9JJ16	CHEMBL3458	Serotonin 3b (5-HT3b) Receptor, Rat	4
5HT4R_CAVPO	O70528	CHEMBL5017	Serotonin 4 (5-HT4) Receptor, Guinea Pig	4
ACM2_HUMAN	P08172	CHEMBL211	Muscarinic Acetylcholine Receptor M2, Human	4
ACM3_HUMAN	P20309	CHEMBL245	Muscarinic Acetylcholine Receptor M3, Human	4
ACM4_HUMAN	P08173	CHEMBL1821	Muscarinic Acetylcholine Receptor M4, Human	4
ACM5_HUMAN	P08912	CHEMBL2035	Muscarinic Acetylcholine Receptor M5, Human	4
5HT2A_BOVIN	Q75Z89	CHEMBL3446	Serotonin 2a (5-HT2a) Receptor, Bovin	3
ACM1_HUMAN	P11229	CHEMBL216	Muscarinic Acetylcholine Receptor M1, Human	3
ADA1A_BOVIN	P18130	CHEMBL4892	Alpha-1a Adrenergic Receptor, Bovin	3
ADA1A_RAT	P43140	CHEMBL319	Alpha-1a Adrenergic Receptor, Rat	3
ADA1D_RAT	P23944	CHEMBL326	Alpha-1d Adrenergic Receptor, Rat	3
DRD1_RAT	P18901	CHEMBL265	Dopamine D1 Receptor, Rat	3
HRH3_HUMAN	Q9Y5N1	CHEMBL264	Histamine H3 Receptor, Human	3
HRH4_HUMAN	Q9H3N8	CHEMBL3759	Histamine H4 Receptor, Human	3
OPRD_HUMAN	P41143	CHEMBL236	Delta Opioid Receptor, Human	3
OPRK_HUMAN	P41145	CHEMBL237	Kappa Opioid Receptor, Human	3
SC6A4_RAT	P31652	CHEMBL313	Serotonin Transporter, Rat	3
SGMR1_RAT	Q9R0C9	CHEMBL3602	Sigma Opioid Receptor, Rat	3
5HT2A_MOUSE	P35363	CHEMBL5377	Serotonin 2a (5-HT2a) Receptor, Mouse	2
5HT2B_MOUSE	Q02152	CHEMBL2583	Serotonin 2b (5-HT2b) Receptor, Mouse	2
5HT2C_MOUSE	P34968	CHEMBL3006	Serotonin 2c (5-HT2c) Receptor, Mouse	2
5HT3A_MOUSE	P23979	CHEMBL4972	Serotonin 3a (5-HT3a) Receptor, Mouse	2
5HT5A_RAT	P35364	CHEMBL4655	Serotonin 5a (5-HT5a) Receptor, Rat	2
ADA2A_BOVIN	Q28838	CHEMBL4744	Alpha-2a Adrenergic Receptor, Bovin	2
ADRB3_HUMAN	P13945	CHEMBL246	Beta-3 Adrenergic Receptor, Human	2
CAC1C_HUMAN	Q13936	CHEMBL1940	Voltage-gated L-type Calcium Channel Alpha-1C Subunit, Human	2
CAC1D_HUMAN	Q01668	CHEMBL4138	Voltage-gated L-type Calcium Channel Alpha-1D Subunit, Human	2
CAC1F_HUMAN	O60840	CHEMBL5593	Voltage-gated L-type Calcium Channel Alpha-1F Subunit, Human	2
CAC1S_HUMAN	Q13698	CHEMBL3805	Voltage-gated L-type Calcium Channel Alpha-1S Subunit, Human	2
DRD4_RAT	P30729	CHEMBL3361	Dopamine D4 Receptor, Rat	2
NISCH_HUMAN	Q9Y2I1	CHEMBL3923	Nischarin, Human	2
SC6A2_HUMAN	P23975	CHEMBL222	Norepinephrine Transporter, Human	2
Z104304	Z104304	CHEMBL1907610	Adrenergic Receptor Alpha-1	2
5HT3B_MOUSE	Q9JHJ5	CHEMBL3781	Serotonin 3b (5-HT3b) Receptor, Mouse	1
5HT4R_RAT	Q62758	CHEMBL4317	Serotonin 4 (5-HT4) Receptor, Rat	1
ACM1_RAT	P08482	CHEMBL276	Muscarinic Acetylcholine Receptor M1, Rat	1
ACM2_RAT	P10980	CHEMBL309	Muscarinic Acetylcholine Receptor M2, Rat	1
ACM3_RAT	P08483	CHEMBL320	Muscarinic Acetylcholine Receptor M3, Rat	1
ACM4_RAT	P08485	CHEMBL317	Muscarinic Acetylcholine Receptor M4, Rat	1
ADA1B_RAT	P15823	CHEMBL315	Alpha-1b Adrenergic Receptor, Rat	1
AOFA_RAT	P21396	CHEMBL3358	Monoamine Oxidase A, Rat	1
AOFB_RAT	P19643	CHEMBL2993	Monoamine Oxidase B, Rat	1
CCKAR_HUMAN	P32238	CHEMBL1901	Cholecystokinin A Receptor, Human	1
CNR2_MOUSE	P47936	CHEMBL5373	Cannabinoid CB2 Receptor, Mouse	1
DRD1_BOVIN	Q95136	CHEMBL2967	Dopamine D1 Receptor, Bovin	1
DRD1_PIG	P50130	CHEMBL5067	Dopamine D1 Receptor, Pig	1
DRD2_CHLAE	P52702	CHEMBL5456	Dopamine D2 Receptor, Chlae	1
DRD2_MOUSE	P61168	CHEMBL3427	Dopamine D2 Receptor, Mouse	1
DRD5_RAT	P25115	CHEMBL2281	Dopamine D5 Receptor, Rat	1
FAAH1_MOUSE	O08914	CHEMBL3455	Anandamide Amidohydrolase, Mouse	1
HRH1_CAVPO	P31389	CHEMBL3943	Histamine H1 Receptor, Guinea Pig	1
HRH1_RAT	P31390	CHEMBL4701	Histamine H1 Receptor, Rat	1
HRH2_RAT	P25102	CHEMBL4654	Histamine H2 Receptor, Rat	1
HRH3_RAT	Q9QYN8	CHEMBL4124	Histamine H3 Receptor, Rat	1
HRH4_RAT	Q91ZY1	CHEMBL4468	Histamine H4 Receptor, Rat	1
KCNH2_HUMAN	Q12809	CHEMBL240	HERG, Human	1
Q63380_RAT	Q63380	CHEMBL6184	Transporter, Rat	1
Q9WTR4_RAT	Q9WTR4	CHEMBL304	Norepinephrine Transporter, Rat	1
Z104303	Z104303	CHEMBL1907609	Muscarinic Acetylcholine Receptor	1