UCSF

Serotonin 5a (5-HT5a) Receptor, Human (175 Compounds)

Swissprot:
5HT5A_HUMAN
Stitch:
5HT5A_HUMAN
UniProt:
P47898
ChEMBL:
CHEMBL3426
Reactome:
REACT_19231
REACT_17064
PDB:
HTR5A

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 175 23 9 5
Binding ≤ 1μM 143 17 6 5

Reactome Network (2)

Reactome ID Description Species
REACT_19231 G alpha (i) signalling events Homo sapiens
REACT_17064 Serotonin receptors Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 74
5HT1B_HUMAN P28222 CHEMBL1898 Serotonin 1b (5-HT1b) Receptor, Human 19
5HT1D_HUMAN P28221 CHEMBL1983 Serotonin 1d (5-HT1d) Receptor, Human 62
5HT1E_HUMAN P28566 CHEMBL2182 Serotonin 1e (5-HT1e) Receptor, Human 20
5HT1F_HUMAN P30939 CHEMBL1805 Serotonin 1f (5-HT1f) Receptor, Human 7
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 6
ACM2_HUMAN P08172 CHEMBL211 Muscarinic Acetylcholine Receptor M2, Human 4
ACM4_HUMAN P08173 CHEMBL1821 Muscarinic Acetylcholine Receptor M4, Human 4
ADA2A_HUMAN P08913 CHEMBL1867 Alpha-2a Adrenergic Receptor, Human 9
ADA2B_HUMAN P18089 CHEMBL1942 Alpha-2b Adrenergic Receptor, Human 8
ADA2C_HUMAN P18825 CHEMBL1916 Alpha-2c Adrenergic Receptor, Human 11
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 26
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 22
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 22
HRH3_HUMAN Q9Y5N1 CHEMBL264 Histamine H3 Receptor, Human 4
HRH4_HUMAN Q9H3N8 CHEMBL3759 Histamine H4 Receptor, Human 3
OPRD_HUMAN P41143 CHEMBL236 Delta Opioid Receptor, Human 3
OPRK_HUMAN P41145 CHEMBL237 Kappa Opioid Receptor, Human 3
OPRM_HUMAN P35372 CHEMBL233 Mu Opioid Receptor, Human 7

Serotonin receptors

Uniprot Swissprot Chembl Description Number Shared
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 74
5HT1B_HUMAN P28222 CHEMBL1898 Serotonin 1b (5-HT1b) Receptor, Human 19
5HT1D_HUMAN P28221 CHEMBL1983 Serotonin 1d (5-HT1d) Receptor, Human 62
5HT1E_HUMAN P28566 CHEMBL2182 Serotonin 1e (5-HT1e) Receptor, Human 20
5HT1F_HUMAN P30939 CHEMBL1805 Serotonin 1f (5-HT1f) Receptor, Human 7
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 26
5HT2B_HUMAN P41595 CHEMBL1833 Serotonin 2b (5-HT2b) Receptor, Human 27
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 62
5HT4R_HUMAN Q13639 CHEMBL1875 Serotonin 4 (5-HT4) Receptor, Human 10
5HT6R_HUMAN P50406 CHEMBL3371 Serotonin 6 (5-HT6) Receptor, Human 39
5HT7R_HUMAN P34969 CHEMBL3155 Serotonin 7 (5-HT7) Receptor, Human 81
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
5HT5A_MOUSE P30966 CHEMBL3597 Serotonin 5a (5-HT5a) Receptor, Mouse 38 7 3 1
5HT5A_RAT P35364 CHEMBL4655 Serotonin 5a (5-HT5a) Receptor, Rat 34 9 8 8

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
5HT7R_HUMAN P34969 CHEMBL3155 Serotonin 7 (5-HT7) Receptor, Human 81
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 74
5HT1D_HUMAN P28221 CHEMBL1983 Serotonin 1d (5-HT1d) Receptor, Human 62
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 62
5HT2A_RAT P14842 CHEMBL322 Serotonin 2a (5-HT2a) Receptor, Rat 40
5HT6R_HUMAN P50406 CHEMBL3371 Serotonin 6 (5-HT6) Receptor, Human 39
5HT2C_RAT P08909 CHEMBL324 Serotonin 2c (5-HT2c) Receptor, Rat 32
5HT2B_HUMAN P41595 CHEMBL1833 Serotonin 2b (5-HT2b) Receptor, Human 27
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 26
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 25
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 22
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 22
HRH1_HUMAN P35367 CHEMBL231 Histamine H1 Receptor, Human 22
5HT1E_HUMAN P28566 CHEMBL2182 Serotonin 1e (5-HT1e) Receptor, Human 20
5HT5A_MOUSE P30966 CHEMBL3597 Serotonin 5a (5-HT5a) Receptor, Mouse 20
5HT1B_HUMAN P28222 CHEMBL1898 Serotonin 1b (5-HT1b) Receptor, Human 19
DRD5_HUMAN P21918 CHEMBL1850 Dopamine D5 Receptor, Human 17
5HT3A_HUMAN P46098 CHEMBL1899 Serotonin 3a (5-HT3a) Receptor, Human 15
ADA1B_HUMAN P35368 CHEMBL232 Alpha-1b Adrenergic Receptor, Human 15
ADA1A_HUMAN P35348 CHEMBL229 Alpha-1a Adrenergic Receptor, Human 14
SC6A4_HUMAN P31645 CHEMBL228 Serotonin Transporter, Human 13
5HT7R_RAT P32305 CHEMBL3223 Serotonin 7 (5-HT7) Receptor, Rat 12
ADA1D_HUMAN P25100 CHEMBL223 Alpha-1d Adrenergic Receptor, Human 12
DRD1_HUMAN P21728 CHEMBL2056 Dopamine D1 Receptor, Human 12
ADA2C_HUMAN P18825 CHEMBL1916 Alpha-2c Adrenergic Receptor, Human 11
5HT1A_RAT P19327 CHEMBL273 Serotonin 1a (5-HT1a) Receptor, Rat 10
5HT4R_HUMAN Q13639 CHEMBL1875 Serotonin 4 (5-HT4) Receptor, Human 10
ADRB1_HUMAN P08588 CHEMBL213 Beta-1 Adrenergic Receptor, Human 10
ADRB2_HUMAN P07550 CHEMBL210 Beta-2 Adrenergic Receptor, Human 10
HRH2_HUMAN P25021 CHEMBL1941 Histamine H2 Receptor, Human 10
ADA2A_HUMAN P08913 CHEMBL1867 Alpha-2a Adrenergic Receptor, Human 9
5HT1B_RAT P28564 CHEMBL3459 Serotonin 1b (5-HT1b) Receptor, Rat 8
5HT2B_RAT P30994 CHEMBL323 Serotonin 2b (5-HT2b) Receptor, Rat 8
5HT3B_HUMAN O95264 CHEMBL3895 Serotonin 3b (5-HT3b) Receptor, Human 8
5HT3C_HUMAN Q8WXA8 CHEMBL4795 Serotonin 3c (5-HT3c) Receptor, Human 8
5HT3D_HUMAN Q70Z44 CHEMBL4673 Serotonin 3d (5-HT3d) Receptor, Human 8
5HT3E_HUMAN A5X5Y0 CHEMBL3812 Serotonin 3e (5-HT3e) Receptor, Human 8
ADA2B_HUMAN P18089 CHEMBL1942 Alpha-2b Adrenergic Receptor, Human 8
5HT1D_RAT P28565 CHEMBL5450 Serotonin 1d (5-HT1d) Receptor, Rat 7
DRD1_MOUSE Q61616 CHEMBL3071 Dopamine D1 Receptor, Mouse 7
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 7
OPRM_HUMAN P35372 CHEMBL233 Mu Opioid Receptor, Human 7
SGMR1_HUMAN Q99720 CHEMBL287 Sigma Opioid Receptor, Human 7
5HT1F_HUMAN P30939 CHEMBL1805 Serotonin 1f (5-HT1f) Receptor, Human 6
5HT1F_RAT P30940 CHEMBL4646 Serotonin 1f (5-HT1f) Receptor, Rat 6
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 6
SC6A3_HUMAN Q01959 CHEMBL238 Dopamine Transporter, Human 6
ADA2A_RAT P22909 CHEMBL327 Alpha-2a Adrenergic Receptor, Rat 5
ADA2B_RAT P19328 CHEMBL266 Alpha-2b Adrenergic Receptor, Rat 5
ADA2C_RAT P22086 CHEMBL314 Alpha-2c Adrenergic Receptor, Rat 5
DRD2_BOVIN P20288 CHEMBL3998 Dopamine D2 Receptor, Bovin 5
DRD3_RAT P19020 CHEMBL3138 Dopamine D3 Receptor, Rat 5
5HT1A_MOUSE Q64264 CHEMBL3737 Serotonin 1a (5-HT1a) Receptor, Mouse 4
5HT3A_RAT P35563 CHEMBL2411 Serotonin 3a (5-HT3a) Receptor, Rat 4
5HT3B_RAT Q9JJ16 CHEMBL3458 Serotonin 3b (5-HT3b) Receptor, Rat 4
5HT4R_CAVPO O70528 CHEMBL5017 Serotonin 4 (5-HT4) Receptor, Guinea Pig 4
ACM2_HUMAN P08172 CHEMBL211 Muscarinic Acetylcholine Receptor M2, Human 4
ACM3_HUMAN P20309 CHEMBL245 Muscarinic Acetylcholine Receptor M3, Human 4
ACM4_HUMAN P08173 CHEMBL1821 Muscarinic Acetylcholine Receptor M4, Human 4
ACM5_HUMAN P08912 CHEMBL2035 Muscarinic Acetylcholine Receptor M5, Human 4
5HT2A_BOVIN Q75Z89 CHEMBL3446 Serotonin 2a (5-HT2a) Receptor, Bovin 3
ACM1_HUMAN P11229 CHEMBL216 Muscarinic Acetylcholine Receptor M1, Human 3
ADA1A_BOVIN P18130 CHEMBL4892 Alpha-1a Adrenergic Receptor, Bovin 3
ADA1A_RAT P43140 CHEMBL319 Alpha-1a Adrenergic Receptor, Rat 3
ADA1D_RAT P23944 CHEMBL326 Alpha-1d Adrenergic Receptor, Rat 3
DRD1_RAT P18901 CHEMBL265 Dopamine D1 Receptor, Rat 3
HRH3_HUMAN Q9Y5N1 CHEMBL264 Histamine H3 Receptor, Human 3
HRH4_HUMAN Q9H3N8 CHEMBL3759 Histamine H4 Receptor, Human 3
OPRD_HUMAN P41143 CHEMBL236 Delta Opioid Receptor, Human 3
OPRK_HUMAN P41145 CHEMBL237 Kappa Opioid Receptor, Human 3
SC6A4_RAT P31652 CHEMBL313 Serotonin Transporter, Rat 3
SGMR1_RAT Q9R0C9 CHEMBL3602 Sigma Opioid Receptor, Rat 3
5HT2A_MOUSE P35363 CHEMBL5377 Serotonin 2a (5-HT2a) Receptor, Mouse 2
5HT2B_MOUSE Q02152 CHEMBL2583 Serotonin 2b (5-HT2b) Receptor, Mouse 2
5HT2C_MOUSE P34968 CHEMBL3006 Serotonin 2c (5-HT2c) Receptor, Mouse 2
5HT3A_MOUSE P23979 CHEMBL4972 Serotonin 3a (5-HT3a) Receptor, Mouse 2
5HT5A_RAT P35364 CHEMBL4655 Serotonin 5a (5-HT5a) Receptor, Rat 2
ADA2A_BOVIN Q28838 CHEMBL4744 Alpha-2a Adrenergic Receptor, Bovin 2
ADRB3_HUMAN P13945 CHEMBL246 Beta-3 Adrenergic Receptor, Human 2
CAC1C_HUMAN Q13936 CHEMBL1940 Voltage-gated L-type Calcium Channel Alpha-1C Subunit, Human 2
CAC1D_HUMAN Q01668 CHEMBL4138 Voltage-gated L-type Calcium Channel Alpha-1D Subunit, Human 2
CAC1F_HUMAN O60840 CHEMBL5593 Voltage-gated L-type Calcium Channel Alpha-1F Subunit, Human 2
CAC1S_HUMAN Q13698 CHEMBL3805 Voltage-gated L-type Calcium Channel Alpha-1S Subunit, Human 2
DRD4_RAT P30729 CHEMBL3361 Dopamine D4 Receptor, Rat 2
NISCH_HUMAN Q9Y2I1 CHEMBL3923 Nischarin, Human 2
SC6A2_HUMAN P23975 CHEMBL222 Norepinephrine Transporter, Human 2
Z104304 Z104304 CHEMBL1907610 Adrenergic Receptor Alpha-1 2
5HT3B_MOUSE Q9JHJ5 CHEMBL3781 Serotonin 3b (5-HT3b) Receptor, Mouse 1
5HT4R_RAT Q62758 CHEMBL4317 Serotonin 4 (5-HT4) Receptor, Rat 1
ACM1_RAT P08482 CHEMBL276 Muscarinic Acetylcholine Receptor M1, Rat 1
ACM2_RAT P10980 CHEMBL309 Muscarinic Acetylcholine Receptor M2, Rat 1
ACM3_RAT P08483 CHEMBL320 Muscarinic Acetylcholine Receptor M3, Rat 1
ACM4_RAT P08485 CHEMBL317 Muscarinic Acetylcholine Receptor M4, Rat 1
ADA1B_RAT P15823 CHEMBL315 Alpha-1b Adrenergic Receptor, Rat 1
AOFA_RAT P21396 CHEMBL3358 Monoamine Oxidase A, Rat 1
AOFB_RAT P19643 CHEMBL2993 Monoamine Oxidase B, Rat 1
CCKAR_HUMAN P32238 CHEMBL1901 Cholecystokinin A Receptor, Human 1
CNR2_MOUSE P47936 CHEMBL5373 Cannabinoid CB2 Receptor, Mouse 1
DRD1_BOVIN Q95136 CHEMBL2967 Dopamine D1 Receptor, Bovin 1
DRD1_PIG P50130 CHEMBL5067 Dopamine D1 Receptor, Pig 1
DRD2_CHLAE P52702 CHEMBL5456 Dopamine D2 Receptor, Chlae 1
DRD2_MOUSE P61168 CHEMBL3427 Dopamine D2 Receptor, Mouse 1
DRD5_RAT P25115 CHEMBL2281 Dopamine D5 Receptor, Rat 1
FAAH1_MOUSE O08914 CHEMBL3455 Anandamide Amidohydrolase, Mouse 1
HRH1_CAVPO P31389 CHEMBL3943 Histamine H1 Receptor, Guinea Pig 1
HRH1_RAT P31390 CHEMBL4701 Histamine H1 Receptor, Rat 1
HRH2_RAT P25102 CHEMBL4654 Histamine H2 Receptor, Rat 1
HRH3_RAT Q9QYN8 CHEMBL4124 Histamine H3 Receptor, Rat 1
HRH4_RAT Q91ZY1 CHEMBL4468 Histamine H4 Receptor, Rat 1
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 1
Q63380_RAT Q63380 CHEMBL6184 Transporter, Rat 1
Q9WTR4_RAT Q9WTR4 CHEMBL304 Norepinephrine Transporter, Rat 1
Z104303 Z104303 CHEMBL1907609 Muscarinic Acetylcholine Receptor 1