UCSF

Muscarinic Acetylcholine Receptor (1,182 Compounds)

Swissprot:
Z104303
Stitch:
Z104303
UniProt:
Z104303
ChEMBL:
CHEMBL1907609

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 1,182 63 33 34
Binding ≤ 1μM 919 57 30 31
Functional ≤ 10μM 0 0 0 0

Reactome Network (0)

Clustered By Gene (0)

Clustered By Organism (6)

Code Description Substances Purchasable Natural In Man
Z104303-1-O Muscarinic Acetylcholine Receptor (cluster #1 Of 7), Other 541 38 18 23
Z104303-2-O Muscarinic Acetylcholine Receptor (cluster #2 Of 7), Other 346 20 11 7
Z104303-3-O Muscarinic Acetylcholine Receptor (cluster #3 Of 7), Other 199 2 2 2
Z104303-4-O Muscarinic Acetylcholine Receptor (cluster #4 Of 7), Other 43 1 2 2
Z104303-5-O Muscarinic Acetylcholine Receptor (cluster #5 Of 7), Other 7 1 1 1
Z104303-6-O Muscarinic Acetylcholine Receptor (cluster #6 Of 7), Other 50 0 0 0
Z104303-7-O Muscarinic Acetylcholine Receptor (cluster #7 Of 7), Other 1 1 1 0
Uniprot Swissprot Chembl Description Number Shared
ACM1_RAT P08482 CHEMBL276 Muscarinic Acetylcholine Receptor M1, Rat 226
ACM2_RAT P10980 CHEMBL309 Muscarinic Acetylcholine Receptor M2, Rat 135
ACM1_HUMAN P11229 CHEMBL216 Muscarinic Acetylcholine Receptor M1, Human 133
ACM2_HUMAN P08172 CHEMBL211 Muscarinic Acetylcholine Receptor M2, Human 108
ACM3_HUMAN P20309 CHEMBL245 Muscarinic Acetylcholine Receptor M3, Human 96
ACM4_HUMAN P08173 CHEMBL1821 Muscarinic Acetylcholine Receptor M4, Human 80
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 80
DRD1_RAT P18901 CHEMBL265 Dopamine D1 Receptor, Rat 76
ACM3_RAT P08483 CHEMBL320 Muscarinic Acetylcholine Receptor M3, Rat 64
ACM5_HUMAN P08912 CHEMBL2035 Muscarinic Acetylcholine Receptor M5, Human 59
5HT2A_RAT P14842 CHEMBL322 Serotonin 2a (5-HT2a) Receptor, Rat 57
5HT2C_RAT P08909 CHEMBL324 Serotonin 2c (5-HT2c) Receptor, Rat 57
ACM4_RAT P08485 CHEMBL317 Muscarinic Acetylcholine Receptor M4, Rat 46
DRD4_RAT P30729 CHEMBL3361 Dopamine D4 Receptor, Rat 46
5HT2B_RAT P30994 CHEMBL323 Serotonin 2b (5-HT2b) Receptor, Rat 45
DRD3_RAT P19020 CHEMBL3138 Dopamine D3 Receptor, Rat 45
DRD5_RAT P25115 CHEMBL2281 Dopamine D5 Receptor, Rat 45
ACH10_RAT Q9JLB5 CHEMBL3461 Neuronal Acetylcholine Receptor Protein Alpha-10 Subunit, Rat 38
ACHA3_RAT P04757 CHEMBL3818 Neuronal Acetylcholine Receptor Protein Alpha-3 Subunit, Rat 38
ACHA4_RAT P09483 CHEMBL307 Neuronal Acetylcholine Receptor Protein Alpha-4 Subunit, Rat 38
ACHA2_RAT P12389 CHEMBL2584 Neuronal Acetylcholine Receptor Protein Alpha-2 Subunit, Rat 26
ACHB2_RAT P12390 CHEMBL3001 Neuronal Acetylcholine Receptor Protein Beta-2 Subunit, Rat 26
ACHB4_RAT P12392 CHEMBL2658 Neuronal Acetylcholine Receptor Protein Beta-4 Subunit, Rat 26
ACHA7_RAT Q05941 CHEMBL4980 Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit, Rat 25
ACHA5_RAT P20420 CHEMBL4960 Neuronal Acetylcholine Receptor Protein Alpha-5 Subunit, Rat 24
ACHA6_RAT P43143 CHEMBL4747 Neuronal Acetylcholine Receptor Protein Alpha-6 Subunit, Rat 24
ACHA9_RAT P43144 CHEMBL2585 Neuronal Acetylcholine Receptor Protein Alpha-9 Subunit, Rat 24
ACHA_RAT P25108 CHEMBL3599 Acetylcholine Receptor Protein Alpha Chain, Rat 24
ACHB3_RAT P12391 CHEMBL4568 Neuronal Acetylcholine Receptor Protein Beta-3 Subunit, Rat 24
ACHB_RAT P25109 CHEMBL2666 Acetylcholine Receptor Protein Beta Chain, Rat 24
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 24
5HT1A_RAT P19327 CHEMBL273 Serotonin 1a (5-HT1a) Receptor, Rat 19
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 19
5HT1B_RAT P28564 CHEMBL3459 Serotonin 1b (5-HT1b) Receptor, Rat 18
5HT1D_RAT P28565 CHEMBL5450 Serotonin 1d (5-HT1d) Receptor, Rat 18
5HT1F_RAT P30940 CHEMBL4646 Serotonin 1f (5-HT1f) Receptor, Rat 18
ACM1_MOUSE P12657 CHEMBL3733 Muscarinic Acetylcholine Receptor M1, Mouse 17
ADA2A_RAT P22909 CHEMBL327 Alpha-2a Adrenergic Receptor, Rat 17
ADA2B_RAT P19328 CHEMBL266 Alpha-2b Adrenergic Receptor, Rat 17
ADA2C_RAT P22086 CHEMBL314 Alpha-2c Adrenergic Receptor, Rat 17
Z104304 Z104304 CHEMBL1907610 Adrenergic Receptor Alpha-1 17
ACHD_TORCA P02718 CHEMBL3916 Acetylcholine Receptor Protein Delta Chain, Torca 16
5HT3A_RAT P35563 CHEMBL2411 Serotonin 3a (5-HT3a) Receptor, Rat 14
5HT3B_RAT Q9JJ16 CHEMBL3458 Serotonin 3b (5-HT3b) Receptor, Rat 14
ADA1A_BOVIN P18130 CHEMBL4892 Alpha-1a Adrenergic Receptor, Bovin 13
ADA2A_BOVIN Q28838 CHEMBL4744 Alpha-2a Adrenergic Receptor, Bovin 10
ACHA3_HUMAN P32297 CHEMBL3068 Neuronal Acetylcholine Receptor Protein Alpha-3 Subunit, Human 9
ACHB2_HUMAN P17787 CHEMBL1883 Neuronal Acetylcholine Receptor Protein Beta-2 Subunit, Human 9
Z104290 Z104290 CHEMBL1907596 Neuronal Acetylcholine Receptor; Alpha4/beta2 9
SGMR1_HUMAN Q99720 CHEMBL287 Sigma Opioid Receptor, Human 8
ACM5_RAT P08911 CHEMBL277 Muscarinic Acetylcholine Receptor M5, Rat 7
DRD2_BOVIN P20288 CHEMBL3998 Dopamine D2 Receptor, Bovin 7
HRH1_RAT P31390 CHEMBL4701 Histamine H1 Receptor, Rat 7
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 7
SCN1A_HUMAN P35498 CHEMBL1845 Sodium Channel Protein Type I Alpha Subunit, Human 7
SCN2A_HUMAN Q99250 CHEMBL4187 Sodium Channel Protein Type II Alpha Subunit, Human 7
SCN3A_HUMAN Q9NY46 CHEMBL5163 Sodium Channel Protein Type III Alpha Subunit, Human 7
SCN8A_HUMAN Q9UQD0 CHEMBL5202 Sodium Channel Protein Type VIII Alpha Subunit, Human 7
ACM2_MOUSE Q9ERZ4 CHEMBL3197 Muscarinic Acetylcholine Receptor M2, Mouse 6
CXCR3_HUMAN P49682 CHEMBL4441 C-X-C Chemokine Receptor Type 3, Human 6
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 6
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 5
5HT7R_RAT P32305 CHEMBL3223 Serotonin 7 (5-HT7) Receptor, Rat 5
ADRB1_RAT P18090 CHEMBL3252 Beta-1 Adrenergic Receptor, Rat 5
ADRB3_RAT P26255 CHEMBL4031 Beta-3 Adrenergic Receptor, Rat 5
DRD1_HUMAN P21728 CHEMBL2056 Dopamine D1 Receptor, Human 5
DRD5_HUMAN P21918 CHEMBL1850 Dopamine D5 Receptor, Human 5
HRH1_HUMAN P35367 CHEMBL231 Histamine H1 Receptor, Human 5
Z104301 Z104301 CHEMBL1907607 GABA-A Receptor; Anion Channel 5
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 4
5HT2C_MOUSE P34968 CHEMBL3006 Serotonin 2c (5-HT2c) Receptor, Mouse 4
5HT7R_HUMAN P34969 CHEMBL3155 Serotonin 7 (5-HT7) Receptor, Human 4
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 4
ADA1A_RAT P43140 CHEMBL319 Alpha-1a Adrenergic Receptor, Rat 4
ADA1B_RAT P15823 CHEMBL315 Alpha-1b Adrenergic Receptor, Rat 4
ADA1D_RAT P23944 CHEMBL326 Alpha-1d Adrenergic Receptor, Rat 4
OPRD_RAT P33533 CHEMBL269 Delta Opioid Receptor, Rat 4
OPRM_RAT P33535 CHEMBL270 Mu Opioid Receptor, Rat 4
Q9WTR4_RAT Q9WTR4 CHEMBL304 Norepinephrine Transporter, Rat 4
SC6A4_HUMAN P31645 CHEMBL228 Serotonin Transporter, Human 4
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 3
5HT2B_HUMAN P41595 CHEMBL1833 Serotonin 2b (5-HT2b) Receptor, Human 3
5HT6R_HUMAN P50406 CHEMBL3371 Serotonin 6 (5-HT6) Receptor, Human 3
ACES_MOUSE P21836 CHEMBL3198 Acetylcholinesterase, Mouse 3
ACM3_MOUSE Q9ERZ3 CHEMBL5105 Muscarinic Acetylcholine Receptor M3, Mouse 3
ACM4_MOUSE P32211 CHEMBL4572 Muscarinic Acetylcholine Receptor M4, Mouse 3
ACM5_MOUSE Q920H4 CHEMBL2324 Muscarinic Acetylcholine Receptor M5, Mouse 3
ADRB2_CANFA P54833 CHEMBL2289 Beta-2 Adrenergic Receptor, Canine 3
DRD1_BOVIN Q95136 CHEMBL2967 Dopamine D1 Receptor, Bovin 3
DRD2_MOUSE P61168 CHEMBL3427 Dopamine D2 Receptor, Mouse 3
PDR5_YEAST P33302 CHEMBL1697658 Pleiotropic ABC Efflux Transporter Of Multiple Drugs, Yeast 3
Q8WMX0_BOVIN Q8WMX0 CHEMBL2672 Muscarinic Acetylcholine Receptor M1, Bovin 3
SC6A4_RAT P31652 CHEMBL313 Serotonin Transporter, Rat 3
5HT2A_BOVIN Q75Z89 CHEMBL3446 Serotonin 2a (5-HT2a) Receptor, Bovin 2
5HT2A_MOUSE P35363 CHEMBL5377 Serotonin 2a (5-HT2a) Receptor, Mouse 2
5HT2B_MOUSE Q02152 CHEMBL2583 Serotonin 2b (5-HT2b) Receptor, Mouse 2
5HT4R_RAT Q62758 CHEMBL4317 Serotonin 4 (5-HT4) Receptor, Rat 2
5HT5A_RAT P35364 CHEMBL4655 Serotonin 5a (5-HT5a) Receptor, Rat 2
5HT5B_RAT P35365 CHEMBL2619 Serotonin 5b (5-HT5b) Receptor, Rat 2
5HT6R_RAT P31388 CHEMBL3372 Serotonin 6 (5-HT6) Receptor, Rat 2
ACES_RAT P37136 CHEMBL3199 Acetylcholinesterase, Rat 2
ADA1A_HUMAN P35348 CHEMBL229 Alpha-1a Adrenergic Receptor, Human 2
ADA1B_HUMAN P35368 CHEMBL232 Alpha-1b Adrenergic Receptor, Human 2
ADA1D_HUMAN P25100 CHEMBL223 Alpha-1d Adrenergic Receptor, Human 2
ADCY1_HUMAN Q08828 CHEMBL2899 Brain Adenylate Cyclase 1, Human 2
ADCY2_HUMAN Q08462 CHEMBL3760 Adenylate Cyclase Type II, Human 2
ADCY8_HUMAN P40145 CHEMBL2960 Adenylate Cyclase Type VIII, Human 2
ADRB2_RAT P10608 CHEMBL3754 Beta-2 Adrenergic Receptor, Rat 2
BKRB2_HUMAN P30411 CHEMBL3157 Bradykinin B2 Receptor, Human 2
DRD1_PIG P50130 CHEMBL5067 Dopamine D1 Receptor, Pig 2
DRD2_CHLAE P52702 CHEMBL5456 Dopamine D2 Receptor, Chlae 2
HRH2_RAT P25102 CHEMBL4654 Histamine H2 Receptor, Rat 2
HRH3_RAT Q9QYN8 CHEMBL4124 Histamine H3 Receptor, Rat 2
HRH4_RAT Q91ZY1 CHEMBL4468 Histamine H4 Receptor, Rat 2
MDR1_HUMAN P08183 CHEMBL4302 P-glycoprotein 1, Human 2
OPRK_HUMAN P41145 CHEMBL237 Kappa Opioid Receptor, Human 2
OPRK_RAT P34975 CHEMBL3614 Kappa Opioid Receptor, Rat 2
PRIO_HUMAN P04156 CHEMBL4869 Prion Protein, Human 2
Q63380_RAT Q63380 CHEMBL6184 Transporter, Rat 2
SC6A2_HUMAN P23975 CHEMBL222 Norepinephrine Transporter, Human 2
SC6A2_MOUSE O55192 CHEMBL2370 Norepinephrine Transporter, Mouse 2
SC6A4_MOUSE Q60857 CHEMBL4642 Serotonin Transporter, Mouse 2
Z100491 Z100491 CHEMBL613288 Sigma 2 Receptor 2
Z104281 Z104281 CHEMBL1907587 Neuronal Acetylcholine Receptor; Alpha3/beta2 2
Z104283 Z104283 CHEMBL1907589 Neuronal Acetylcholine Receptor; Alpha4/beta2 2
Z104286 Z104286 CHEMBL1907592 Neuronal Acetylcholine Receptor; Alpha2/beta2 2
Z104287 Z104287 CHEMBL1907593 Neuronal Acetylcholine Receptor; Alpha3/beta4 2
Z104289 Z104289 CHEMBL1907595 Neuronal Acetylcholine Receptor; Alpha4/beta4 2
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 2
5HT1A_MOUSE Q64264 CHEMBL3737 Serotonin 1a (5-HT1a) Receptor, Mouse 1
5HT1E_HUMAN P28566 CHEMBL2182 Serotonin 1e (5-HT1e) Receptor, Human 1
5HT2A_PIG P50129 CHEMBL2490 Serotonin 2a (5-HT2a) Receptor, Pig 1
5HT3A_MOUSE P23979 CHEMBL4972 Serotonin 3a (5-HT3a) Receptor, Mouse 1
5HT5A_HUMAN P47898 CHEMBL3426 Serotonin 5a (5-HT5a) Receptor, Human 1
ACES_BOVIN P23795 CHEMBL4768 Acetylcholinesterase, Bovin 1
ACES_ELEEL O42275 CHEMBL4078 Acetylcholinesterase, Eleel 1
ACES_HUMAN P22303 CHEMBL220 Acetylcholinesterase, Human 1
ACES_TORCA P04058 CHEMBL4780 Acetylcholinesterase, Torca 1
ACHA2_HUMAN Q15822 CHEMBL1794 Neuronal Acetylcholine Receptor Protein Alpha-2 Subunit, Human 1
ACHB4_HUMAN P30926 CHEMBL3002 Neuronal Acetylcholine Receptor Protein Beta-4 Subunit, Human 1
ACHE_HUMAN Q04844 CHEMBL2484 Acetylcholine Receptor Protein Epsilon Chain, Human 1
ACHP_LYMST P58154 CHEMBL6084 Acetylcholine-binding Protein, Lymst 1
ACM2_PIG P06199 CHEMBL4781 Muscarinic Acetylcholine Receptor M2, Pig 1
ADA2A_HUMAN P08913 CHEMBL1867 Alpha-2a Adrenergic Receptor, Human 1
ADA2B_HUMAN P18089 CHEMBL1942 Alpha-2b Adrenergic Receptor, Human 1
ADA2C_HUMAN P18825 CHEMBL1916 Alpha-2c Adrenergic Receptor, Human 1
ADCY2_RAT P26769 CHEMBL2958 Adenylate Cyclase Type II, Rat 1
ADCY3_RAT P21932 CHEMBL4864 Adenylate Cyclase Type III, Rat 1
ADCY4_RAT P26770 CHEMBL2879 Adenylate Cyclase Type IV, Rat 1
ADCY5_RAT Q04400 CHEMBL2880 Adenylate Cyclase Type V, Rat 1
ADCY6_RAT Q03343 CHEMBL2975 Adenylate Cyclase Type VI, Rat 1
ADCY8_RAT P40146 CHEMBL3082 Adenylate Cyclase Type VIII, Rat 1
AP2S1_RAT P62744 CHEMBL1697667 AP-2 Complex Subunit Sigma, Rat 1
CALM_HUMAN P62158 CHEMBL6093 Calmodulin, Human 1
CHLE_HORSE P81908 CHEMBL5763 Cholinesterase, Horse 1
CHLE_HUMAN P06276 CHEMBL1914 Butyrylcholinesterase, Human 1
CLAT_RAT P32738 CHEMBL3945 Choline Acetylase, Rat 1
D4A3N4_RAT D4A3N4 CHEMBL2679 Brain Adenylate Cyclase 1, Rat 1
EBP_HUMAN Q15125 CHEMBL4931 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase, Human 1
ERG2_YEAST P32352 CHEMBL3224 C-8 Sterol Isomerase, Yeast 1
HNMT_RAT Q01984 CHEMBL3241 Histamine N-methyltransferase, Rat 1
HRH4_HUMAN Q9H3N8 CHEMBL3759 Histamine H4 Receptor, Human 1
NMD3A_HUMAN Q8TCU5 CHEMBL4787 Glutamate [NMDA] Receptor Subunit 3A, Human 1
NMD3B_HUMAN O60391 CHEMBL2913 Glutamate [NMDA] Receptor Subunit 3B, Human 1
NMDE1_HUMAN Q12879 CHEMBL1972 Glutamate [NMDA] Receptor Subunit Epsilon 1, Human 1
NMDE2_HUMAN Q13224 CHEMBL1904 Glutamate [NMDA] Receptor Subunit Epsilon 2, Human 1
NMDE3_HUMAN Q14957 CHEMBL4109 Glutamate [NMDA] Receptor Subunit Epsilon 3, Human 1
NMDE4_HUMAN O15399 CHEMBL2591 Glutamate [NMDA] Receptor Subunit Epsilon 4, Human 1
NMDZ1_HUMAN Q05586 CHEMBL2015 Glutamate (NMDA) Receptor Subunit Zeta 1, Human 1
P97706_RAT P97706 CHEMBL4957 Sodium Channel Protein Type VI Alpha Subunit, Rat 1
Q4U254_9ENTO Q4U254 CHEMBL2857 Human Rhinovirus A Protease, 9ento 1
Q72874_9HIV1 Q72874 CHEMBL243 Human Immunodeficiency Virus Type 1 Protease, 9hiv1 1
Q8CFM9_RAT Q8CFM9 CHEMBL3940 Adenylate Cyclase Type VII, Rat 1
Q9JKC1_RAT Q9JKC1 CHEMBL3403 Butyrylcholinesterase, Rat 1
Q9N1N9_HORSE Q9N1N9 CHEMBL5077 Butyrylcholinesterase, Horse 1
SC6A3_MOUSE Q61327 CHEMBL2799 Dopamine Transporter, Mouse 1
SC6A3_RAT P23977 CHEMBL338 Dopamine Transporter, Rat 1
SCN5A_RAT P15389 CHEMBL3866 Sodium Channel Protein Type V Alpha Subunit, Rat 1
SGMR1_CAVPO Q60492 CHEMBL4153 Sigma-1 Receptor, Guinea Pig 1
SGMR1_RAT Q9R0C9 CHEMBL3602 Sigma Opioid Receptor, Rat 1
TRPV1_RAT O35433 CHEMBL5102 Vanilloid Receptor, Rat 1
TYTR_TRYCR P28593 CHEMBL5131 Trypanothione Reductase, Trycr 1
Z104285 Z104285 CHEMBL1907591 Neuronal Acetylcholine Receptor; Alpha4/beta4 1
Z104288 Z104288 CHEMBL1907594 Neuronal Acetylcholine Receptor; Alpha3/beta4 1
Z104298 Z104298 CHEMBL1907604 Glutamate NMDA Receptor; GRIN1/GRIN2A 1
Z104302 Z104302 CHEMBL1907608 Glutamate NMDA Receptor 1

Most Common Rings