ZINC 12

User Information

Not Authenticated — sign in

Active cart: Temporary Cart (0 items)

Navigation

About
- ZINC
- BCIRC
- Irwin Lab
- Shoichet Lab
- UCSF
- Acknowledgements
- Facts
- Usage
Search
- By:
- Text
- Structure
- Properties
- Catalogs
- ZINC
- Targets
- Rings
- Combination
Subsets
- By:
- Catalog
- Property
- Target
- Ring
- Cart
Help
- Introduction
- FAQ
- Scripting/API
- Quick Search
- Problems
- Filtering
- History
Social
- ZINC Fans
- Decoy Club
- DOCK Fans
- Facebook
- Twitter
- Blog
- Linkedin
Quick Search ZINC ID or SMILES

Names
Compounds (17)
Reactome (0)
Related By:
Pathway (0)
Organism (0)
Gene (49)
Org. Clust. (0)
ChEMBL (70)
Rings (5)

Sodium Channel Protein Type VI Alpha Subunit, Rat (17 Compounds)

Swissprot:: P97706_RAT
Stitch:: P97706_RAT
UniProt:: P97706
ChEMBL:: CHEMBL4957

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	17	8	7	7
Binding ≤ 1μM	8	5	3	3
Functional ≤ 10μM	20	8	6	7

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
P2RX1_RAT	P47824	CHEMBL2530	P2X Purinoceptor 1, Rat	3	3	0	0
P2RX4_RAT	P51577	CHEMBL2818	P2X Purinoceptor 4, Rat	1	0	0	0
P2RX7_RAT	Q64663	CHEMBL2496	P2X Purinoceptor 7, Rat	19	8	0	0
P4HA1_RAT	P54001	CHEMBL3301	Prolyl 4-hydroxylase Alpha-1 Subunit, Rat	2	2	0	0
PA21B_RAT	P04055	CHEMBL5016	Phospholipase A2 Group 1B, Rat	8	0	0	0
PA2GA_RAT	P14423	CHEMBL3686	Phospholipase A2 Group IIA, Rat	7	0	0	0
PAI1_RAT	P20961	CHEMBL2155	Plasminogen Activator Inhibitor-1, Rat	1	1	1	1
PARP1_RAT	P27008	CHEMBL4664	Poly [ADP-ribose] Polymerase 1, Rat	32	0	0	0
PCKGC_RAT	P07379	CHEMBL1075234	Phosphoenolpyruvate Carboxykinase, Cytosolic [GTP], Rat	9	1	0	1
PCSK6_RAT	Q63415	CHEMBL5507	Proprotein Convertase Subtilisin/kexin Type 6, Rat	0	0	0	0
PDE10_RAT	Q9QYJ6	CHEMBL6140	CAMP And CAMP-inhibited CGMP 3',5'-cyclic Phosphodiesterase 10A, Rat	40	2	1	4
PDE1B_RAT	Q01066	CHEMBL3665	Phosphodiesterase 1B, Rat	35	7	3	3
PDE1C_RAT	Q63421	CHEMBL2651	Phosphodiesterase 1C, Rat	20	6	2	2
PDE2A_RAT	Q01062	CHEMBL4650	Phosphodiesterase 2A, Rat	2	0	0	0
PDE3A_RAT	Q62865	CHEMBL2711	Phosphodiesterase 3A, Rat	4	1	4	1
PDE3B_RAT	Q63085	CHEMBL3580	Phosphodiesterase 3B, Rat	4	1	4	1
PDE4A_RAT	P54748	CHEMBL4964	Phosphodiesterase 4A, Rat	232	12	14	11
PDE4B_RAT	P14646	CHEMBL3382	Phosphodiesterase 4B, Rat	250	12	14	11
PDE4C_RAT	P14644	CHEMBL4562	Phosphodiesterase 4C, Rat	196	12	12	10
PDE4D_RAT	P14270	CHEMBL2712	Phosphodiesterase 4D, Rat	233	12	14	11
PDE5A_RAT	O54735	CHEMBL4567	Phosphodiesterase 5A, Rat	45	2	7	2
PDE7A_RAT	O08593	CHEMBL3450	Phosphodiesterase 7A, Rat	16	0	0	0
PDK1_RAT	Q63065	CHEMBL2416	Pyruvate Dehydrogenase Kinase Isoform 1, Rat	48	2	0	1
PDK2_RAT	Q64536	CHEMBL3601	Pyruvate Dehydrogenase Kinase Isoform 2, Rat	48	2	0	1
PE2R1_RAT	P70597	CHEMBL5068	Prostanoid EP1 Receptor, Rat	2	0	0	0
PE2R2_RAT	Q62928	CHEMBL4909	Prostanoid EP2 Receptor, Rat	46	2	2	2
PE2R3_RAT	P34980	CHEMBL5674	Prostaglandin E2 Receptor EP3 Subtype, Rat	3	0	0	0
PE2R4_RAT	P43114	CHEMBL4086	Prostanoid EP4 Receptor, Rat	79	1	1	1
PEPC_RAT	P04073	CHEMBL2152	Pepsinogen C, Rat	5	0	0	0
PGFRA_RAT	P20786	CHEMBL2513	Platelet-derived Growth Factor Receptor Alpha, Rat	47	6	0	1
PGFRB_RAT	Q05030	CHEMBL4125	Platelet-derived Growth Factor Receptor Beta, Rat	18	5	0	0
PGH1_RAT	Q63921	CHEMBL4042	Cyclooxygenase-1, Rat	252	34	20	18
PGH2_RAT	P35355	CHEMBL2977	Cyclooxygenase-2, Rat	279	32	18	16
PGTB1_RAT	P53610	CHEMBL3989	Geranylgeranyl Transferase Type I Beta Subunit, Rat	5	0	0	0
PH4H_RAT	P04176	CHEMBL3077	Phenylalanine-4-hydroxylase, Rat	7	2	0	0
PLCG1_RAT	P10686	CHEMBL5188	1-phosphatidylinositol-4,5-bisphosphate Phosphodiesterase Gamma-1, Rat	1	0	0	0
PLCL1_RAT	Q62688	CHEMBL3364	Inositol 1,4,5-trisphosphate Binding Protein, Rat	8	4	4	4
PLMN_RAT	Q01177	CHEMBL3204	Plasminogen, Rat	47	1	0	1
PNPH_RAT	P85973	CHEMBL2395	Purine-nucleoside Phosphorylase, Rat	28	3	2	2
PPARA_RAT	P37230	CHEMBL2129	Peroxisome Proliferator-activated Receptor Alpha, Rat	4	1	1	1
PPARG_RAT	O88275	CHEMBL4797	Peroxisome Proliferator-activated Receptor Gamma, Rat	91	6	5	5
PPBT_RAT	P08289	CHEMBL2729	Alkaline Phosphatase Tissue-nonspecific, Rat	2	1	2	2
PPCE_RAT	O70196	CHEMBL4035	Prolyl Endopeptidase, Rat	68	4	0	3
PPIA_RAT	P10111	CHEMBL2780	Cyclophilin A, Rat	34	1	0	0
PRGR_RAT	Q63449	CHEMBL2596	Progesterone Receptor, Rat	16	4	2	3
PTAFR_RAT	P46002	CHEMBL4127	Platelet Activating Factor Receptor, Rat	4	1	0	0
PTN1_RAT	P20417	CHEMBL2371	Protein-tyrosine Phosphatase 1B, Rat	11	0	0	0
PYGL_RAT	P09811	CHEMBL3239	Liver Glycogen Phosphorylase, Rat	12	2	1	7
PYRD_RAT	Q63707	CHEMBL2383	Dihydroorotate Dehydrogenase, Rat	65	4	1	4

Clustered By Gene (0)

Uniprot	Swissprot	Chembl	Description	Number Shared
SCN5A_RAT	P15389	CHEMBL3866	Sodium Channel Protein Type V Alpha Subunit, Rat	27
SCN2A_RAT	P04775	CHEMBL3399	Sodium Channel Protein Type II Alpha Subunit, Rat	16
SCN8A_RAT	O88420	CHEMBL2752	Sodium Channel Protein Type VIII Alpha Subunit, Rat	13
Z50597	Z50597	CHEMBL376	Rattus Norvegicus	10
SCN1A_RAT	P04774	CHEMBL4906	Sodium Channel Protein Type I Alpha Subunit, Rat	9
SCN3A_RAT	P08104	CHEMBL4966	Sodium Channel Protein Type III Alpha Subunit, Rat	9
CAC1B_RAT	Q02294	CHEMBL5107	Voltage-gated N-type Calcium Channel Alpha-1B Subunit, Rat	7
CAC1A_RAT	P54282	CHEMBL4417	Voltage-gated P/Q-type Calcium Channel Alpha-1A Subunit, Rat	5
CAC1E_RAT	Q07652	CHEMBL4115	Voltage-gated R-type Calcium Channel Alpha-1E Subunit, Rat	5
SCN2A_HUMAN	Q99250	CHEMBL4187	Sodium Channel Protein Type II Alpha Subunit, Human	5
CAC1D_RAT	P27732	CHEMBL4132	Voltage-gated L-type Calcium Channel Alpha-1D Subunit, Rat	3
CAC1G_RAT	O54898	CHEMBL4257	Voltage-gated T-type Calcium Channel Alpha-1G Subunit, Rat	3
CAC1H_RAT	Q9EQ60	CHEMBL5134	Voltage-gated T-type Calcium Channel Alpha-1H Subunit, Rat	3
CAC1I_RAT	Q9Z0Y8	CHEMBL5459	Voltage-gated T-type Calcium Channel Alpha-1I Subunit, Rat	3
CCR5_HUMAN	P51681	CHEMBL274	C-C Chemokine Receptor Type 5, Human	3
KCNH2_HUMAN	Q12809	CHEMBL240	HERG, Human	3
SCN4A_RAT	P15390	CHEMBL3509	Sodium Channel Protein Type IV Alpha Subunit, Rat	3
SCN9A_RAT	O08562	CHEMBL3312	Sodium Channel Protein Type IX Alpha Subunit, Rat	3
SCNAA_RAT	Q62968	CHEMBL4017	Sodium Channel Protein Type X Alpha Subunit, Rat	3
SCNBA_RAT	O88457	CHEMBL2629	Sodium Channel Protein Type XI Alpha Subunit, Rat	3
Z50425	Z50425	CHEMBL364	Plasmodium Falciparum	3
ADRB1_RAT	P18090	CHEMBL3252	Beta-1 Adrenergic Receptor, Rat	2
CA2D1_RAT	P54290	CHEMBL3420	Voltage-gated Calcium Channel Alpha2/delta Subunit 1, Rat	2
CAC1B_HUMAN	Q00975	CHEMBL4478	Voltage-gated N-type Calcium Channel Alpha-1B Subunit, Human	2
CACB1_RAT	P54283	CHEMBL1075136	Voltage-dependent L-type Calcium Channel Subunit Beta-1, Rat	2
SCN1A_HUMAN	P35498	CHEMBL1845	Sodium Channel Protein Type I Alpha Subunit, Human	2
SCN3A_HUMAN	Q9NY46	CHEMBL5163	Sodium Channel Protein Type III Alpha Subunit, Human	2
SCN8A_HUMAN	Q9UQD0	CHEMBL5202	Sodium Channel Protein Type VIII Alpha Subunit, Human	2
Z50466	Z50466	CHEMBL368	Trypanosoma Cruzi	2
ACM1_RAT	P08482	CHEMBL276	Muscarinic Acetylcholine Receptor M1, Rat	1
ACM2_RAT	P10980	CHEMBL309	Muscarinic Acetylcholine Receptor M2, Rat	1
ADA2A_RAT	P22909	CHEMBL327	Alpha-2a Adrenergic Receptor, Rat	1
ADA2B_RAT	P19328	CHEMBL266	Alpha-2b Adrenergic Receptor, Rat	1
ADA2C_RAT	P22086	CHEMBL314	Alpha-2c Adrenergic Receptor, Rat	1
CAC1C_HUMAN	Q13936	CHEMBL1940	Voltage-gated L-type Calcium Channel Alpha-1C Subunit, Human	1
CAC1C_RABIT	P15381	CHEMBL2830	Voltage-gated L-type Calcium Channel Alpha-1C Subunit, Rabit	1
CAC1C_RAT	P22002	CHEMBL3762	Voltage-gated L-type Calcium Channel Alpha-1C Subunit, Rat	1
CAC1D_HUMAN	Q01668	CHEMBL4138	Voltage-gated L-type Calcium Channel Alpha-1D Subunit, Human	1
CAC1G_HUMAN	O43497	CHEMBL4641	Voltage-gated T-type Calcium Channel Alpha-1G Subunit, Human	1
CAC1H_HUMAN	O95180	CHEMBL1859	Voltage-gated T-type Calcium Channel Alpha-1H Subunit, Human	1
CAC1I_HUMAN	Q9P0X4	CHEMBL5558	Voltage-gated T-type Calcium Channel Alpha-1I Subunit, Human	1
CAC1S_RAT	Q02485	CHEMBL4108	Voltage-gated L-type Calcium Channel Alpha-1S Subunit, Rat	1
DRD2_RAT	P61169	CHEMBL339	Dopamine D2 Receptor, Rat	1
DRD3_HUMAN	P35462	CHEMBL234	Dopamine D3 Receptor, Human	1
MDR1_HUMAN	P08183	CHEMBL4302	P-glycoprotein 1, Human	1
MDR1_MOUSE	P06795	CHEMBL3467	P-glycoprotein 1, Mouse	1
MDR3_MOUSE	P21447	CHEMBL2573	P-glycoprotein 3, Mouse	1
MRP1_HUMAN	P33527	CHEMBL3004	Multidrug Resistance-associated Protein 1, Human	1
OPRD_HUMAN	P41143	CHEMBL236	Delta Opioid Receptor, Human	1
OPRK_HUMAN	P41145	CHEMBL237	Kappa Opioid Receptor, Human	1
OPRM_HUMAN	P35372	CHEMBL233	Mu Opioid Receptor, Human	1
S22A1_HUMAN	O15245	CHEMBL5685	Solute Carrier Family 22 Member 1, Human	1
SC6A3_HUMAN	Q01959	CHEMBL238	Dopamine Transporter, Human	1
TSPO_RAT	P16257	CHEMBL4552	Peripheral-type Benzodiazepine Receptor, Rat	1
Z104303	Z104303	CHEMBL1907609	Muscarinic Acetylcholine Receptor	1
Z104304	Z104304	CHEMBL1907610	Adrenergic Receptor Alpha-1	1
Z50512	Z50512	CHEMBL369	Cavia Porcellus	1
Z50592	Z50592	CHEMBL374	Oryctolagus Cuniculus	1
Z80133	Z80133	CHEMBL614294	EMT6 (Mammary Carcinoma Cells)	1
Z80224	Z80224	CHEMBL387	MCF7 (Breast Carcinoma Cells)	1
Z80232	Z80232	CHEMBL614128	MCF7-VP	1
Z80362	Z80362	CHEMBL389	P388 (Lymphoma Cells)	1
Z80364	Z80364	CHEMBL614218	P388/ADR (Lymphoma Cells)	1
Z80532	Z80532	CHEMBL614774	T-24 (Bladder Carcinoma Cells)	1
Z80711	Z80711	CHEMBL613829	NCI/ADR-RES (Breast Carcinoma Cells)	1
Z80773	Z80773	CHEMBL614456	CHRC/5 Cell Line	1
Z80774	Z80774	CHEMBL614457	CHRC5 Cell Line	1
Z80928	Z80928	CHEMBL394	HCT-116 (Colon Carcinoma Cells)	1
Z81008	Z81008	CHEMBL614788	Human Breast Cancer Cell Lines	1
Z81245	Z81245	CHEMBL614697	MDA-MB-435 (Breast Carcinoma Cells)	1