UCSF

Peroxisome Proliferator-activated Receptor Gamma, Rat (91 Compounds)

Swissprot:
PPARG_RAT
Stitch:
PPARG_RAT
UniProt:
O88275
ChEMBL:
CHEMBL4797
Reactome:
REACT_242509
REACT_196408
REACT_260360
PDB:
Pparg

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 91 6 5 5
Binding ≤ 1μM 79 6 5 5
Functional ≤ 10μM 1 0 0 0

Reactome Network (3)

Reactome ID Description Species
REACT_242509 Nuclear Receptor transcription pathway Rattus norvegicus
REACT_196408 PPARA activates gene expression Rattus norvegicus
REACT_260360 Transcriptional regulation of white adipocyte differentiation Rattus norvegicus
Uniprot Swissprot Chembl Description Number Shared
D3ZWV0_RAT D3ZWV0 CHEMBL2630 Retinoic Acid Receptor Gamma, Rat 3
Q499N1_RAT Q499N1 CHEMBL2269 Retinoic Acid Receptor Alpha, Rat 12
RXRG_RAT Q5BJR8 CHEMBL4277 Retinoid X Receptor Gamma, Rat 16
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
PPARG_HUMAN P37231 CHEMBL235 Peroxisome Proliferator-activated Receptor Gamma, Human 1,767 48 20 29
PPARG_MOUSE P37238 CHEMBL2459 Peroxisome Proliferator-activated Receptor Gamma, Mouse 12 8 3 3

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
PPARG-1-E Peroxisome Proliferator-activated Receptor Gamma (cluster #1 Of 2), Eukaryotic 1,820 53 22 33
PPARG-2-E Peroxisome Proliferator-activated Receptor Gamma (cluster #2 Of 2), Eukaryotic 17 3 2 0
Uniprot Swissprot Chembl Description Number Shared
PPARG_HUMAN P37231 CHEMBL235 Peroxisome Proliferator-activated Receptor Gamma, Human 73
PPARA_HUMAN Q07869 CHEMBL239 Peroxisome Proliferator-activated Receptor Alpha, Human 56
PPARD_HUMAN Q03181 CHEMBL3979 Peroxisome Proliferator-activated Receptor Delta, Human 56
RXRA_RAT Q05343 CHEMBL4431 Retinoid X Receptor Alpha, Rat 18
RXRB_RAT P49743 CHEMBL2805 Retinoid X Receptor Beta, Rat 16
RXRG_RAT Q5BJR8 CHEMBL4277 Retinoid X Receptor Gamma, Rat 16
Q499N1_RAT Q499N1 CHEMBL2269 Retinoic Acid Receptor Alpha, Rat 12
RARB_HUMAN P10826 CHEMBL2008 Retinoic Acid Receptor Beta, Human 9
AOFB_HUMAN P27338 CHEMBL2039 Monoamine Oxidase B, Human 4
RARG_HUMAN P13631 CHEMBL2003 Retinoic Acid Receptor Gamma, Human 4
D3ZWV0_RAT D3ZWV0 CHEMBL2630 Retinoic Acid Receptor Gamma, Rat 3
PPARG_MOUSE P37238 CHEMBL2459 Peroxisome Proliferator-activated Receptor Gamma, Mouse 3
RARA_HUMAN P10276 CHEMBL2055 Retinoic Acid Receptor Alpha, Human 2
RXRA_HUMAN P19793 CHEMBL2061 Retinoid X Receptor Alpha, Human 2
RXRB_HUMAN P28702 CHEMBL1870 Retinoid X Receptor Beta, Human 2
RXRG_HUMAN P48443 CHEMBL2004 Retinoid X Receptor Gamma, Human 2
RXRB_MOUSE P28704 CHEMBL4047 Retinoid X Receptor Beta, Mouse 1
RXRG_MOUSE P28705 CHEMBL4402 Retinoid X Receptor Gamma, Mouse 1