UCSF

Retinoid X Receptor Gamma, Human (110 Compounds)

Swissprot:
RXRG_HUMAN
Stitch:
RXRG_HUMAN
UniProt:
P48443
ChEMBL:
CHEMBL2004
Reactome:
REACT_15525
PDB:
2GL8 (DOCK)
RXRG

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 110 8 4 4
Binding ≤ 1μM 98 8 4 4
Functional ≤ 10μM 55 5 3 3

Reactome Network (1)

Reactome ID Description Species
REACT_15525 Nuclear Receptor transcription pathway Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
PPARG_HUMAN P37231 CHEMBL235 Peroxisome Proliferator-activated Receptor Gamma, Human 17
RARA_HUMAN P10276 CHEMBL2055 Retinoic Acid Receptor Alpha, Human 41
RARB_HUMAN P10826 CHEMBL2008 Retinoic Acid Receptor Beta, Human 46
RARG_HUMAN P13631 CHEMBL2003 Retinoic Acid Receptor Gamma, Human 33
RXRA_HUMAN P19793 CHEMBL2061 Retinoid X Receptor Alpha, Human 125
RXRB_HUMAN P28702 CHEMBL1870 Retinoid X Receptor Beta, Human 120
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
RXRG_MOUSE P28705 CHEMBL4402 Retinoid X Receptor Gamma, Mouse 65 5 4 4
RXRG_RAT Q5BJR8 CHEMBL4277 Retinoid X Receptor Gamma, Rat 17 2 1 1

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
RXRA_HUMAN P19793 CHEMBL2061 Retinoid X Receptor Alpha, Human 125
RXRB_HUMAN P28702 CHEMBL1870 Retinoid X Receptor Beta, Human 120
RARB_HUMAN P10826 CHEMBL2008 Retinoic Acid Receptor Beta, Human 46
RARA_HUMAN P10276 CHEMBL2055 Retinoic Acid Receptor Alpha, Human 41
RARG_HUMAN P13631 CHEMBL2003 Retinoic Acid Receptor Gamma, Human 33
RXRB_MOUSE P28704 CHEMBL4047 Retinoid X Receptor Beta, Mouse 21
RXRG_MOUSE P28705 CHEMBL4402 Retinoid X Receptor Gamma, Mouse 20
RXRA_MOUSE P28700 CHEMBL3084 Retinoid X Receptor Alpha, Mouse 10
RARA_MOUSE P11416 CHEMBL2792 Retinoic Acid Receptor Alpha, Mouse 8
RARB_MOUSE P22605 CHEMBL3266 Retinoic Acid Receptor Beta, Mouse 8
RARG_MOUSE P18911 CHEMBL4177 Retinoic Acid Receptor Gamma, Mouse 7
Z80156 Z80156 CHEMBL383 HL-60 (Promyeloblast Leukemia Cells) 6
Z50594 Z50594 CHEMBL375 Mus Musculus 5
RXRA_RAT Q05343 CHEMBL4431 Retinoid X Receptor Alpha, Rat 3
PPARG_RAT O88275 CHEMBL4797 Peroxisome Proliferator-activated Receptor Gamma, Rat 2
RXRB_RAT P49743 CHEMBL2805 Retinoid X Receptor Beta, Rat 2
RXRG_RAT Q5BJR8 CHEMBL4277 Retinoid X Receptor Gamma, Rat 2
NR1H4_HUMAN Q96RI1 CHEMBL2047 Bile Acid Receptor FXR, Human 1
PPARG_HUMAN P37231 CHEMBL235 Peroxisome Proliferator-activated Receptor Gamma, Human 1
Q499N1_RAT Q499N1 CHEMBL2269 Retinoic Acid Receptor Alpha, Rat 1
RABP1_CHICK P40220 CHEMBL4945 Cellular Retinoic Acid-binding Protein I, Chick 1
RABP1_MOUSE P62965 CHEMBL3208 Cellular Retinoic Acid-binding Protein I, Mouse 1
RABP2_MOUSE P22935 CHEMBL4172 Cellular Retinoic Acid-binding Protein II, Mouse 1
Z50518 Z50518 CHEMBL613124 Human Herpesvirus 4 1
Z80135 Z80135 CHEMBL614296 F9 1
Z80166 Z80166 CHEMBL384 HT-29 (Colon Adenocarcinoma Cells) 1
Z80224 Z80224 CHEMBL387 MCF7 (Breast Carcinoma Cells) 1
Z80377 Z80377 CHEMBL614228 PaCa2 1
Z80390 Z80390 CHEMBL390 PC-3 (Prostate Carcinoma Cells) 1
Z80475 Z80475 CHEMBL613834 SK-BR-3 (Breast Adenocarcinoma) 1
Z80712 Z80712 CHEMBL614361 T47D (Breast Carcinoma Cells) 1
Z81170 Z81170 CHEMBL612518 LNCaP (Prostate Carcinoma) 1

Most Common Rings