UCSF

Sodium Channel Protein Type II Alpha Subunit, Rat (250 Compounds)

Swissprot:
SCN2A_RAT
Stitch:
SCN2A_RAT
UniProt:
P04775
ChEMBL:
CHEMBL3399
PDB:
1BYY (DOCK)
2KXW (DOCK)

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 250 20 7 8
Binding ≤ 1μM 181 7 4 4
Functional ≤ 10μM 92 10 6 6

Reactome Network (0)

UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
SCN2A_HUMAN Q99250 CHEMBL4187 Sodium Channel Protein Type II Alpha Subunit, Human 180 80 69 76

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
SCN2A-1-E Sodium Channel Protein Type II Alpha Subunit (cluster #1 Of 2), Eukaryotic 241 70 51 54
SCN2A-2-E Sodium Channel Protein Type II Alpha Subunit (cluster #2 Of 2), Eukaryotic 188 29 24 29
Uniprot Swissprot Chembl Description Number Shared
SCN3A_RAT P08104 CHEMBL4966 Sodium Channel Protein Type III Alpha Subunit, Rat 237
SCN1A_RAT P04774 CHEMBL4906 Sodium Channel Protein Type I Alpha Subunit, Rat 236
SCN8A_RAT O88420 CHEMBL2752 Sodium Channel Protein Type VIII Alpha Subunit, Rat 120
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 34
P97706_RAT P97706 CHEMBL4957 Sodium Channel Protein Type VI Alpha Subunit, Rat 16
SCN5A_RAT P15389 CHEMBL3866 Sodium Channel Protein Type V Alpha Subunit, Rat 16
CAC1B_RAT Q02294 CHEMBL5107 Voltage-gated N-type Calcium Channel Alpha-1B Subunit, Rat 11
CAC1A_RAT P54282 CHEMBL4417 Voltage-gated P/Q-type Calcium Channel Alpha-1A Subunit, Rat 10
CAC1E_RAT Q07652 CHEMBL4115 Voltage-gated R-type Calcium Channel Alpha-1E Subunit, Rat 10
Z104302 Z104302 CHEMBL1907608 Glutamate NMDA Receptor 10
CAC1G_RAT O54898 CHEMBL4257 Voltage-gated T-type Calcium Channel Alpha-1G Subunit, Rat 9
CAC1H_RAT Q9EQ60 CHEMBL5134 Voltage-gated T-type Calcium Channel Alpha-1H Subunit, Rat 9
CAC1I_RAT Q9Z0Y8 CHEMBL5459 Voltage-gated T-type Calcium Channel Alpha-1I Subunit, Rat 9
5HT2A_RAT P14842 CHEMBL322 Serotonin 2a (5-HT2a) Receptor, Rat 6
5HT2B_RAT P30994 CHEMBL323 Serotonin 2b (5-HT2b) Receptor, Rat 6
5HT2C_RAT P08909 CHEMBL324 Serotonin 2c (5-HT2c) Receptor, Rat 6
ADA2A_RAT P22909 CHEMBL327 Alpha-2a Adrenergic Receptor, Rat 6
ADA2B_RAT P19328 CHEMBL266 Alpha-2b Adrenergic Receptor, Rat 6
ADA2C_RAT P22086 CHEMBL314 Alpha-2c Adrenergic Receptor, Rat 6
SGMR1_HUMAN Q99720 CHEMBL287 Sigma Opioid Receptor, Human 6
Z104304 Z104304 CHEMBL1907610 Adrenergic Receptor Alpha-1 6
SCN2A_HUMAN Q99250 CHEMBL4187 Sodium Channel Protein Type II Alpha Subunit, Human 5
SGMR1_RAT Q9R0C9 CHEMBL3602 Sigma Opioid Receptor, Rat 5
5HT1A_RAT P19327 CHEMBL273 Serotonin 1a (5-HT1a) Receptor, Rat 4
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 4
5HT1B_RAT P28564 CHEMBL3459 Serotonin 1b (5-HT1b) Receptor, Rat 3
5HT1D_RAT P28565 CHEMBL5450 Serotonin 1d (5-HT1d) Receptor, Rat 3
5HT1F_RAT P30940 CHEMBL4646 Serotonin 1f (5-HT1f) Receptor, Rat 3
ADA1A_RAT P43140 CHEMBL319 Alpha-1a Adrenergic Receptor, Rat 3
ADA1B_RAT P15823 CHEMBL315 Alpha-1b Adrenergic Receptor, Rat 3
CCR5_HUMAN P51681 CHEMBL274 C-C Chemokine Receptor Type 5, Human 3
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 3
SCN4A_RAT P15390 CHEMBL3509 Sodium Channel Protein Type IV Alpha Subunit, Rat 3
SCN9A_RAT O08562 CHEMBL3312 Sodium Channel Protein Type IX Alpha Subunit, Rat 3
SCNAA_RAT Q62968 CHEMBL4017 Sodium Channel Protein Type X Alpha Subunit, Rat 3
SCNBA_RAT O88457 CHEMBL2629 Sodium Channel Protein Type XI Alpha Subunit, Rat 3
ADA2A_HUMAN P08913 CHEMBL1867 Alpha-2a Adrenergic Receptor, Human 2
ADA2B_HUMAN P18089 CHEMBL1942 Alpha-2b Adrenergic Receptor, Human 2
AOFB_RAT P19643 CHEMBL2993 Monoamine Oxidase B, Rat 2
CAC1D_RAT P27732 CHEMBL4132 Voltage-gated L-type Calcium Channel Alpha-1D Subunit, Rat 2
CAC1G_HUMAN O43497 CHEMBL4641 Voltage-gated T-type Calcium Channel Alpha-1G Subunit, Human 2
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 2
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 2
OPRD_HUMAN P41143 CHEMBL236 Delta Opioid Receptor, Human 2
OPRK_HUMAN P41145 CHEMBL237 Kappa Opioid Receptor, Human 2
OPRM_HUMAN P35372 CHEMBL233 Mu Opioid Receptor, Human 2
SCN1A_HUMAN P35498 CHEMBL1845 Sodium Channel Protein Type I Alpha Subunit, Human 2
SCN3A_HUMAN Q9NY46 CHEMBL5163 Sodium Channel Protein Type III Alpha Subunit, Human 2
SCN8A_HUMAN Q9UQD0 CHEMBL5202 Sodium Channel Protein Type VIII Alpha Subunit, Human 2
SCN9A_HUMAN Q15858 CHEMBL4296 Sodium Channel Protein Type IX Alpha Subunit, Human 2
Z100491 Z100491 CHEMBL613288 Sigma 2 Receptor 2
Z50425 Z50425 CHEMBL364 Plasmodium Falciparum 2
5HT6R_HUMAN P50406 CHEMBL3371 Serotonin 6 (5-HT6) Receptor, Human 1
5HT7R_RAT P32305 CHEMBL3223 Serotonin 7 (5-HT7) Receptor, Rat 1
ACM1_RAT P08482 CHEMBL276 Muscarinic Acetylcholine Receptor M1, Rat 1
ACM2_RAT P10980 CHEMBL309 Muscarinic Acetylcholine Receptor M2, Rat 1
ACM3_RAT P08483 CHEMBL320 Muscarinic Acetylcholine Receptor M3, Rat 1
AOFB_HUMAN P27338 CHEMBL2039 Monoamine Oxidase B, Human 1
CA2D1_RAT P54290 CHEMBL3420 Voltage-gated Calcium Channel Alpha2/delta Subunit 1, Rat 1
CAC1B_HUMAN Q00975 CHEMBL4478 Voltage-gated N-type Calcium Channel Alpha-1B Subunit, Human 1
CAC1C_RAT P22002 CHEMBL3762 Voltage-gated L-type Calcium Channel Alpha-1C Subunit, Rat 1
CAC1F_HUMAN O60840 CHEMBL5593 Voltage-gated L-type Calcium Channel Alpha-1F Subunit, Human 1
CAC1H_HUMAN O95180 CHEMBL1859 Voltage-gated T-type Calcium Channel Alpha-1H Subunit, Human 1
CAC1I_HUMAN Q9P0X4 CHEMBL5558 Voltage-gated T-type Calcium Channel Alpha-1I Subunit, Human 1
CAC1S_HUMAN Q13698 CHEMBL3805 Voltage-gated L-type Calcium Channel Alpha-1S Subunit, Human 1
CACB1_RAT P54283 CHEMBL1075136 Voltage-dependent L-type Calcium Channel Subunit Beta-1, Rat 1
CNGA1_BOVIN Q00194 CHEMBL4907 CGMP-gated Cation Channel Alpha 1, Bovin 1
DRD1_RAT P18901 CHEMBL265 Dopamine D1 Receptor, Rat 1
DRD2_BOVIN P20288 CHEMBL3998 Dopamine D2 Receptor, Bovin 1
DRD3_RAT P19020 CHEMBL3138 Dopamine D3 Receptor, Rat 1
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 1
DRD4_RAT P30729 CHEMBL3361 Dopamine D4 Receptor, Rat 1
DRD5_RAT P25115 CHEMBL2281 Dopamine D5 Receptor, Rat 1
HRH1_HUMAN P35367 CHEMBL231 Histamine H1 Receptor, Human 1
NK1R_HUMAN P25103 CHEMBL249 Neurokinin 1 Receptor, Human 1
NMD3A_HUMAN Q8TCU5 CHEMBL4787 Glutamate [NMDA] Receptor Subunit 3A, Human 1
NMD3B_HUMAN O60391 CHEMBL2913 Glutamate [NMDA] Receptor Subunit 3B, Human 1
NMDE1_HUMAN Q12879 CHEMBL1972 Glutamate [NMDA] Receptor Subunit Epsilon 1, Human 1
NMDE2_HUMAN Q13224 CHEMBL1904 Glutamate [NMDA] Receptor Subunit Epsilon 2, Human 1
NMDE3_HUMAN Q14957 CHEMBL4109 Glutamate [NMDA] Receptor Subunit Epsilon 3, Human 1
NMDE4_HUMAN O15399 CHEMBL2591 Glutamate [NMDA] Receptor Subunit Epsilon 4, Human 1
NMDZ1_HUMAN Q05586 CHEMBL2015 Glutamate (NMDA) Receptor Subunit Zeta 1, Human 1
OPRD_MOUSE P32300 CHEMBL3222 Delta Opioid Receptor, Mouse 1
OPRK_MOUSE P33534 CHEMBL4329 Kappa Opioid Receptor, Mouse 1
OPRM_MOUSE P42866 CHEMBL2858 Mu Opioid Receptor, Mouse 1
S29A1_HUMAN Q99808 CHEMBL1997 Equilibrative Nucleoside Transporter 1, Human 1
SC6A3_HUMAN Q01959 CHEMBL238 Dopamine Transporter, Human 1
SGMR1_CAVPO Q60492 CHEMBL4153 Sigma-1 Receptor, Guinea Pig 1
SGMR1_MOUSE O55242 CHEMBL3465 Sigma Opioid Receptor, Mouse 1
Z50512 Z50512 CHEMBL369 Cavia Porcellus 1