ZINC 12

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Quick Search ZINC ID or SMILES

Names
Compounds (250)
Reactome (0)
Related By:
Pathway (0)
Organism (1)
Gene (0)
Org. Clust. (1)
ChEMBL (90)
Rings (5)

Sodium Channel Protein Type II Alpha Subunit, Rat (250 Compounds)

Swissprot:: SCN2A_RAT
Stitch:: SCN2A_RAT
UniProt:: P04775
ChEMBL:: CHEMBL3399
PDB:: 1BYY (DOCK); 2KXW (DOCK)

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	250	20	7	8
Binding ≤ 1μM	181	7	4	4
Functional ≤ 10μM	92	10	6	6

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
SCN2A_HUMAN	Q99250	CHEMBL4187	Sodium Channel Protein Type II Alpha Subunit, Human	180	80	69	76

Clustered By Gene (0)

Clustered By Organism (1)

Code	Description	Substances	Purchasable	Natural	In Man
SCN2A-1-E	Sodium Channel Protein Type II Alpha Subunit (cluster #1 Of 2), Eukaryotic	241	70	51	54
SCN2A-2-E	Sodium Channel Protein Type II Alpha Subunit (cluster #2 Of 2), Eukaryotic	188	29	24	29

Uniprot	Swissprot	Chembl	Description	Number Shared
SCN3A_RAT	P08104	CHEMBL4966	Sodium Channel Protein Type III Alpha Subunit, Rat	237
SCN1A_RAT	P04774	CHEMBL4906	Sodium Channel Protein Type I Alpha Subunit, Rat	236
SCN8A_RAT	O88420	CHEMBL2752	Sodium Channel Protein Type VIII Alpha Subunit, Rat	120
Z50597	Z50597	CHEMBL376	Rattus Norvegicus	34
P97706_RAT	P97706	CHEMBL4957	Sodium Channel Protein Type VI Alpha Subunit, Rat	16
SCN5A_RAT	P15389	CHEMBL3866	Sodium Channel Protein Type V Alpha Subunit, Rat	16
CAC1B_RAT	Q02294	CHEMBL5107	Voltage-gated N-type Calcium Channel Alpha-1B Subunit, Rat	11
CAC1A_RAT	P54282	CHEMBL4417	Voltage-gated P/Q-type Calcium Channel Alpha-1A Subunit, Rat	10
CAC1E_RAT	Q07652	CHEMBL4115	Voltage-gated R-type Calcium Channel Alpha-1E Subunit, Rat	10
Z104302	Z104302	CHEMBL1907608	Glutamate NMDA Receptor	10
CAC1G_RAT	O54898	CHEMBL4257	Voltage-gated T-type Calcium Channel Alpha-1G Subunit, Rat	9
CAC1H_RAT	Q9EQ60	CHEMBL5134	Voltage-gated T-type Calcium Channel Alpha-1H Subunit, Rat	9
CAC1I_RAT	Q9Z0Y8	CHEMBL5459	Voltage-gated T-type Calcium Channel Alpha-1I Subunit, Rat	9
5HT2A_RAT	P14842	CHEMBL322	Serotonin 2a (5-HT2a) Receptor, Rat	6
5HT2B_RAT	P30994	CHEMBL323	Serotonin 2b (5-HT2b) Receptor, Rat	6
5HT2C_RAT	P08909	CHEMBL324	Serotonin 2c (5-HT2c) Receptor, Rat	6
ADA2A_RAT	P22909	CHEMBL327	Alpha-2a Adrenergic Receptor, Rat	6
ADA2B_RAT	P19328	CHEMBL266	Alpha-2b Adrenergic Receptor, Rat	6
ADA2C_RAT	P22086	CHEMBL314	Alpha-2c Adrenergic Receptor, Rat	6
SGMR1_HUMAN	Q99720	CHEMBL287	Sigma Opioid Receptor, Human	6
Z104304	Z104304	CHEMBL1907610	Adrenergic Receptor Alpha-1	6
SCN2A_HUMAN	Q99250	CHEMBL4187	Sodium Channel Protein Type II Alpha Subunit, Human	5
SGMR1_RAT	Q9R0C9	CHEMBL3602	Sigma Opioid Receptor, Rat	5
5HT1A_RAT	P19327	CHEMBL273	Serotonin 1a (5-HT1a) Receptor, Rat	4
DRD2_HUMAN	P14416	CHEMBL217	Dopamine D2 Receptor, Human	4
5HT1B_RAT	P28564	CHEMBL3459	Serotonin 1b (5-HT1b) Receptor, Rat	3
5HT1D_RAT	P28565	CHEMBL5450	Serotonin 1d (5-HT1d) Receptor, Rat	3
5HT1F_RAT	P30940	CHEMBL4646	Serotonin 1f (5-HT1f) Receptor, Rat	3
ADA1A_RAT	P43140	CHEMBL319	Alpha-1a Adrenergic Receptor, Rat	3
ADA1B_RAT	P15823	CHEMBL315	Alpha-1b Adrenergic Receptor, Rat	3
CCR5_HUMAN	P51681	CHEMBL274	C-C Chemokine Receptor Type 5, Human	3
DRD3_HUMAN	P35462	CHEMBL234	Dopamine D3 Receptor, Human	3
SCN4A_RAT	P15390	CHEMBL3509	Sodium Channel Protein Type IV Alpha Subunit, Rat	3
SCN9A_RAT	O08562	CHEMBL3312	Sodium Channel Protein Type IX Alpha Subunit, Rat	3
SCNAA_RAT	Q62968	CHEMBL4017	Sodium Channel Protein Type X Alpha Subunit, Rat	3
SCNBA_RAT	O88457	CHEMBL2629	Sodium Channel Protein Type XI Alpha Subunit, Rat	3
ADA2A_HUMAN	P08913	CHEMBL1867	Alpha-2a Adrenergic Receptor, Human	2
ADA2B_HUMAN	P18089	CHEMBL1942	Alpha-2b Adrenergic Receptor, Human	2
AOFB_RAT	P19643	CHEMBL2993	Monoamine Oxidase B, Rat	2
CAC1D_RAT	P27732	CHEMBL4132	Voltage-gated L-type Calcium Channel Alpha-1D Subunit, Rat	2
CAC1G_HUMAN	O43497	CHEMBL4641	Voltage-gated T-type Calcium Channel Alpha-1G Subunit, Human	2
DRD2_RAT	P61169	CHEMBL339	Dopamine D2 Receptor, Rat	2
KCNH2_HUMAN	Q12809	CHEMBL240	HERG, Human	2
OPRD_HUMAN	P41143	CHEMBL236	Delta Opioid Receptor, Human	2
OPRK_HUMAN	P41145	CHEMBL237	Kappa Opioid Receptor, Human	2
OPRM_HUMAN	P35372	CHEMBL233	Mu Opioid Receptor, Human	2
SCN1A_HUMAN	P35498	CHEMBL1845	Sodium Channel Protein Type I Alpha Subunit, Human	2
SCN3A_HUMAN	Q9NY46	CHEMBL5163	Sodium Channel Protein Type III Alpha Subunit, Human	2
SCN8A_HUMAN	Q9UQD0	CHEMBL5202	Sodium Channel Protein Type VIII Alpha Subunit, Human	2
SCN9A_HUMAN	Q15858	CHEMBL4296	Sodium Channel Protein Type IX Alpha Subunit, Human	2
Z100491	Z100491	CHEMBL613288	Sigma 2 Receptor	2
Z50425	Z50425	CHEMBL364	Plasmodium Falciparum	2
5HT6R_HUMAN	P50406	CHEMBL3371	Serotonin 6 (5-HT6) Receptor, Human	1
5HT7R_RAT	P32305	CHEMBL3223	Serotonin 7 (5-HT7) Receptor, Rat	1
ACM1_RAT	P08482	CHEMBL276	Muscarinic Acetylcholine Receptor M1, Rat	1
ACM2_RAT	P10980	CHEMBL309	Muscarinic Acetylcholine Receptor M2, Rat	1
ACM3_RAT	P08483	CHEMBL320	Muscarinic Acetylcholine Receptor M3, Rat	1
AOFB_HUMAN	P27338	CHEMBL2039	Monoamine Oxidase B, Human	1
CA2D1_RAT	P54290	CHEMBL3420	Voltage-gated Calcium Channel Alpha2/delta Subunit 1, Rat	1
CAC1B_HUMAN	Q00975	CHEMBL4478	Voltage-gated N-type Calcium Channel Alpha-1B Subunit, Human	1
CAC1C_RAT	P22002	CHEMBL3762	Voltage-gated L-type Calcium Channel Alpha-1C Subunit, Rat	1
CAC1F_HUMAN	O60840	CHEMBL5593	Voltage-gated L-type Calcium Channel Alpha-1F Subunit, Human	1
CAC1H_HUMAN	O95180	CHEMBL1859	Voltage-gated T-type Calcium Channel Alpha-1H Subunit, Human	1
CAC1I_HUMAN	Q9P0X4	CHEMBL5558	Voltage-gated T-type Calcium Channel Alpha-1I Subunit, Human	1
CAC1S_HUMAN	Q13698	CHEMBL3805	Voltage-gated L-type Calcium Channel Alpha-1S Subunit, Human	1
CACB1_RAT	P54283	CHEMBL1075136	Voltage-dependent L-type Calcium Channel Subunit Beta-1, Rat	1
CNGA1_BOVIN	Q00194	CHEMBL4907	CGMP-gated Cation Channel Alpha 1, Bovin	1
DRD1_RAT	P18901	CHEMBL265	Dopamine D1 Receptor, Rat	1
DRD2_BOVIN	P20288	CHEMBL3998	Dopamine D2 Receptor, Bovin	1
DRD3_RAT	P19020	CHEMBL3138	Dopamine D3 Receptor, Rat	1
DRD4_HUMAN	P21917	CHEMBL219	Dopamine D4 Receptor, Human	1
DRD4_RAT	P30729	CHEMBL3361	Dopamine D4 Receptor, Rat	1
DRD5_RAT	P25115	CHEMBL2281	Dopamine D5 Receptor, Rat	1
HRH1_HUMAN	P35367	CHEMBL231	Histamine H1 Receptor, Human	1
NK1R_HUMAN	P25103	CHEMBL249	Neurokinin 1 Receptor, Human	1
NMD3A_HUMAN	Q8TCU5	CHEMBL4787	Glutamate [NMDA] Receptor Subunit 3A, Human	1
NMD3B_HUMAN	O60391	CHEMBL2913	Glutamate [NMDA] Receptor Subunit 3B, Human	1
NMDE1_HUMAN	Q12879	CHEMBL1972	Glutamate [NMDA] Receptor Subunit Epsilon 1, Human	1
NMDE2_HUMAN	Q13224	CHEMBL1904	Glutamate [NMDA] Receptor Subunit Epsilon 2, Human	1
NMDE3_HUMAN	Q14957	CHEMBL4109	Glutamate [NMDA] Receptor Subunit Epsilon 3, Human	1
NMDE4_HUMAN	O15399	CHEMBL2591	Glutamate [NMDA] Receptor Subunit Epsilon 4, Human	1
NMDZ1_HUMAN	Q05586	CHEMBL2015	Glutamate (NMDA) Receptor Subunit Zeta 1, Human	1
OPRD_MOUSE	P32300	CHEMBL3222	Delta Opioid Receptor, Mouse	1
OPRK_MOUSE	P33534	CHEMBL4329	Kappa Opioid Receptor, Mouse	1
OPRM_MOUSE	P42866	CHEMBL2858	Mu Opioid Receptor, Mouse	1
S29A1_HUMAN	Q99808	CHEMBL1997	Equilibrative Nucleoside Transporter 1, Human	1
SC6A3_HUMAN	Q01959	CHEMBL238	Dopamine Transporter, Human	1
SGMR1_CAVPO	Q60492	CHEMBL4153	Sigma-1 Receptor, Guinea Pig	1
SGMR1_MOUSE	O55242	CHEMBL3465	Sigma Opioid Receptor, Mouse	1
Z50512	Z50512	CHEMBL369	Cavia Porcellus	1