UCSF

Sigma Opioid Receptor, Mouse (205 Compounds)

Swissprot:
SGMR1_MOUSE
Stitch:
SGMR1_MOUSE
UniProt:
O55242
ChEMBL:
CHEMBL3465

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 205 11 8 7
Binding ≤ 1μM 187 9 6 5
Functional ≤ 10μM 11 0 0 0

Reactome Network (0)

UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
SGMR1_CAVPO Q60492 CHEMBL4153 Sigma-1 Receptor, Guinea Pig 823 43 14 13
SGMR1_HUMAN Q99720 CHEMBL287 Sigma Opioid Receptor, Human 1,873 230 56 56
SGMR1_RAT Q9R0C9 CHEMBL3602 Sigma Opioid Receptor, Rat 1,157 146 42 57

Clustered By Gene (0)

Clustered By Organism (5)

Code Description Substances Purchasable Natural In Man
SGMR1-1-E Sigma Opioid Receptor (cluster #1 Of 6), Eukaryotic 3,485 332 79 95
SGMR1-2-E Sigma Opioid Receptor (cluster #2 Of 6), Eukaryotic 15 6 3 3
SGMR1-3-E Sigma Opioid Receptor (cluster #3 Of 6), Eukaryotic 135 9 7 4
SGMR1-4-E Sigma Opioid Receptor (cluster #4 Of 6), Eukaryotic 193 26 3 3
SGMR1-5-E Sigma Opioid Receptor (cluster #5 Of 6), Eukaryotic 1 1 1 0
SGMR1-6-E Sigma Opioid Receptor (cluster #6 Of 6), Eukaryotic 42 5 1 1
Uniprot Swissprot Chembl Description Number Shared
DRD2_MOUSE P61168 CHEMBL3427 Dopamine D2 Receptor, Mouse 102
5HT2A_MOUSE P35363 CHEMBL5377 Serotonin 2a (5-HT2a) Receptor, Mouse 99
5HT2B_MOUSE Q02152 CHEMBL2583 Serotonin 2b (5-HT2b) Receptor, Mouse 99
5HT2C_MOUSE P34968 CHEMBL3006 Serotonin 2c (5-HT2c) Receptor, Mouse 99
OPRK_MOUSE P33534 CHEMBL4329 Kappa Opioid Receptor, Mouse 68
OPRM_MOUSE P42866 CHEMBL2858 Mu Opioid Receptor, Mouse 68
OPRD_MOUSE P32300 CHEMBL3222 Delta Opioid Receptor, Mouse 57
Z100491 Z100491 CHEMBL613288 Sigma 2 Receptor 23
SGMR1_RAT Q9R0C9 CHEMBL3602 Sigma Opioid Receptor, Rat 18
SGMR1_HUMAN Q99720 CHEMBL287 Sigma Opioid Receptor, Human 15
OPRD_HUMAN P41143 CHEMBL236 Delta Opioid Receptor, Human 13
OPRM_HUMAN P35372 CHEMBL233 Mu Opioid Receptor, Human 13
OPRK_HUMAN P41145 CHEMBL237 Kappa Opioid Receptor, Human 12
OPRM_RAT P33535 CHEMBL270 Mu Opioid Receptor, Rat 10
OPRD_RAT P33533 CHEMBL269 Delta Opioid Receptor, Rat 9
OPRK_RAT P34975 CHEMBL3614 Kappa Opioid Receptor, Rat 8
OPRM_BOVIN P79350 CHEMBL3041 Mu Opioid Receptor, Bovin 5
SGMR1_CAVPO Q60492 CHEMBL4153 Sigma-1 Receptor, Guinea Pig 5
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 3
5HT2A_RAT P14842 CHEMBL322 Serotonin 2a (5-HT2a) Receptor, Rat 3
5HT2B_HUMAN P41595 CHEMBL1833 Serotonin 2b (5-HT2b) Receptor, Human 3
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 3
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 3
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 3
OPRK_CAVPO P41144 CHEMBL3952 Kappa Opioid Receptor, Guinea Pig 3
Z104304 Z104304 CHEMBL1907610 Adrenergic Receptor Alpha-1 3
5HT1A_RAT P19327 CHEMBL273 Serotonin 1a (5-HT1a) Receptor, Rat 2
5HT2B_RAT P30994 CHEMBL323 Serotonin 2b (5-HT2b) Receptor, Rat 2
5HT2C_RAT P08909 CHEMBL324 Serotonin 2c (5-HT2c) Receptor, Rat 2
NMD3A_HUMAN Q8TCU5 CHEMBL4787 Glutamate [NMDA] Receptor Subunit 3A, Human 2
NMD3B_HUMAN O60391 CHEMBL2913 Glutamate [NMDA] Receptor Subunit 3B, Human 2
NMDE1_HUMAN Q12879 CHEMBL1972 Glutamate [NMDA] Receptor Subunit Epsilon 1, Human 2
NMDE2_HUMAN Q13224 CHEMBL1904 Glutamate [NMDA] Receptor Subunit Epsilon 2, Human 2
NMDE3_HUMAN Q14957 CHEMBL4109 Glutamate [NMDA] Receptor Subunit Epsilon 3, Human 2
NMDE4_HUMAN O15399 CHEMBL2591 Glutamate [NMDA] Receptor Subunit Epsilon 4, Human 2
NMDZ1_HUMAN Q05586 CHEMBL2015 Glutamate (NMDA) Receptor Subunit Zeta 1, Human 2
OPRM_CAVPO P97266 CHEMBL4354 Mu Opioid Receptor, Guinea Pig 2
SC6A4_RAT P31652 CHEMBL313 Serotonin Transporter, Rat 2
Z104302 Z104302 CHEMBL1907608 Glutamate NMDA Receptor 2
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 2
5HT3A_HUMAN P46098 CHEMBL1899 Serotonin 3a (5-HT3a) Receptor, Human 1
ADA2A_HUMAN P08913 CHEMBL1867 Alpha-2a Adrenergic Receptor, Human 1
EBP_CAVPO Q60490 CHEMBL5525 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase, Guinea Pig 1
NMD3B_RAT Q8VHN2 CHEMBL282 Glutamate [NMDA] Receptor Subunit 3B, Rat 1
NMDE2_RAT Q00960 CHEMBL311 Glutamate [NMDA] Receptor Subunit Epsilon 2, Rat 1
NMDE3_RAT Q00961 CHEMBL401 Glutamate [NMDA] Receptor Subunit Epsilon 3, Rat 1
NMDE4_RAT Q62645 CHEMBL303 Glutamate [NMDA] Receptor Subunit Epsilon 4, Rat 1
OPRD_PIG P79291 CHEMBL4103 Delta Opioid Receptor, Pig 1
OPRX_HUMAN P41146 CHEMBL2014 Nociceptin Receptor, Human 1
PDYN_HUMAN P01213 CHEMBL2227 Proenkephalin B, Human 1
Q9WTR4_RAT Q9WTR4 CHEMBL304 Norepinephrine Transporter, Rat 1
SC6A3_RAT P23977 CHEMBL338 Dopamine Transporter, Rat 1
SCN1A_RAT P04774 CHEMBL4906 Sodium Channel Protein Type I Alpha Subunit, Rat 1
SCN2A_RAT P04775 CHEMBL3399 Sodium Channel Protein Type II Alpha Subunit, Rat 1
SCN3A_RAT P08104 CHEMBL4966 Sodium Channel Protein Type III Alpha Subunit, Rat 1
SCN8A_RAT O88420 CHEMBL2752 Sodium Channel Protein Type VIII Alpha Subunit, Rat 1
Z100254 Z100254 CHEMBL613295 Monoclonal Antibody (mAb) 3E7 1
Z50594 Z50594 CHEMBL375 Mus Musculus 1