ZINC 12

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Quick Search ZINC ID or SMILES

Names
Compounds (482)
Reactome (0)
Related By:
Pathway (0)
Organism (3)
Gene (0)
Org. Clust. (5)
ChEMBL (54)
Rings (37)

Kappa Opioid Receptor, Guinea Pig (482 Compounds)

Swissprot:: OPRK_CAVPO
Stitch:: OPRK_CAVPO
UniProt:: P41144
ChEMBL:: CHEMBL3952
PDB:: OPRK1

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	482	25	19	19
Binding ≤ 1μM	403	23	14	17
Functional ≤ 10μM	38	1	1	0

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
OPRK_HUMAN	P41145	CHEMBL237	Kappa Opioid Receptor, Human	3,585	110	54	58
OPRK_MOUSE	P33534	CHEMBL4329	Kappa Opioid Receptor, Mouse	125	13	9	8
OPRK_RAT	P34975	CHEMBL3614	Kappa Opioid Receptor, Rat	568	51	34	45

Clustered By Gene (0)

Clustered By Organism (5)

Code	Description	Substances	Purchasable	Natural	In Man
OPRK-1-E	Kappa Opioid Receptor (cluster #1 Of 6), Eukaryotic	4,070	135	65	88
OPRK-2-E	Kappa Opioid Receptor (cluster #2 Of 6), Eukaryotic	3	3	1	1
OPRK-3-E	Kappa Opioid Receptor (cluster #3 Of 6), Eukaryotic	269	8	8	5
OPRK-4-E	Kappa Opioid Receptor (cluster #4 Of 6), Eukaryotic	265	14	5	9
OPRK-5-E	Kappa Opioid Receptor (cluster #5 Of 6), Eukaryotic	10	1	4	0
OPRK-6-E	Kappa Opioid Receptor (cluster #6 Of 6), Eukaryotic	1	0	1	1

Uniprot	Swissprot	Chembl	Description	Number Shared
OPRM_RAT	P33535	CHEMBL270	Mu Opioid Receptor, Rat	195
OPRD_HUMAN	P41143	CHEMBL236	Delta Opioid Receptor, Human	182
OPRM_CAVPO	P97266	CHEMBL4354	Mu Opioid Receptor, Guinea Pig	180
OPRK_HUMAN	P41145	CHEMBL237	Kappa Opioid Receptor, Human	162
OPRM_HUMAN	P35372	CHEMBL233	Mu Opioid Receptor, Human	146
OPRD_RAT	P33533	CHEMBL269	Delta Opioid Receptor, Rat	139
OPRM_MOUSE	P42866	CHEMBL2858	Mu Opioid Receptor, Mouse	53
OPRX_HUMAN	P41146	CHEMBL2014	Nociceptin Receptor, Human	48
OPRK_RAT	P34975	CHEMBL3614	Kappa Opioid Receptor, Rat	44
OPRD_PIG	P79291	CHEMBL4103	Delta Opioid Receptor, Pig	37
OPRD_MOUSE	P32300	CHEMBL3222	Delta Opioid Receptor, Mouse	34
Z50597	Z50597	CHEMBL376	Rattus Norvegicus	34
Z50512	Z50512	CHEMBL369	Cavia Porcellus	32
SGMR1_HUMAN	Q99720	CHEMBL287	Sigma Opioid Receptor, Human	22
SGMR1_CAVPO	Q60492	CHEMBL4153	Sigma-1 Receptor, Guinea Pig	16
SGMR1_RAT	Q9R0C9	CHEMBL3602	Sigma Opioid Receptor, Rat	12
Z100491	Z100491	CHEMBL613288	Sigma 2 Receptor	11
OPRK_MOUSE	P33534	CHEMBL4329	Kappa Opioid Receptor, Mouse	9
KCNH2_HUMAN	Q12809	CHEMBL240	HERG, Human	4
NMD3B_RAT	Q8VHN2	CHEMBL282	Glutamate [NMDA] Receptor Subunit 3B, Rat	3
NMDE2_RAT	Q00960	CHEMBL311	Glutamate [NMDA] Receptor Subunit Epsilon 2, Rat	3
NMDE3_RAT	Q00961	CHEMBL401	Glutamate [NMDA] Receptor Subunit Epsilon 3, Rat	3
NMDE4_RAT	Q62645	CHEMBL303	Glutamate [NMDA] Receptor Subunit Epsilon 4, Rat	3
OPRM_BOVIN	P79350	CHEMBL3041	Mu Opioid Receptor, Bovin	3
SGMR1_MOUSE	O55242	CHEMBL3465	Sigma Opioid Receptor, Mouse	3
Z104302	Z104302	CHEMBL1907608	Glutamate NMDA Receptor	2
AA3R_HUMAN	P33765	CHEMBL256	Adenosine A3 Receptor, Human	1
ACES_ELEEL	O42275	CHEMBL4078	Acetylcholinesterase, Eleel	1
ACM1_RAT	P08482	CHEMBL276	Muscarinic Acetylcholine Receptor M1, Rat	1
ACM2_RAT	P10980	CHEMBL309	Muscarinic Acetylcholine Receptor M2, Rat	1
ADA2A_HUMAN	P08913	CHEMBL1867	Alpha-2a Adrenergic Receptor, Human	1
AOFA_HUMAN	P21397	CHEMBL1951	Monoamine Oxidase A, Human	1
AOFB_HUMAN	P27338	CHEMBL2039	Monoamine Oxidase B, Human	1
CCR5_MOUSE	P51682	CHEMBL3676	C-C Chemokine Receptor Type 5, Mouse	1
GASR_HUMAN	P32239	CHEMBL298	Cholecystokinin B Receptor, Human	1
NMD3A_HUMAN	Q8TCU5	CHEMBL4787	Glutamate [NMDA] Receptor Subunit 3A, Human	1
NMD3B_HUMAN	O60391	CHEMBL2913	Glutamate [NMDA] Receptor Subunit 3B, Human	1
NMDE1_HUMAN	Q12879	CHEMBL1972	Glutamate [NMDA] Receptor Subunit Epsilon 1, Human	1
NMDE2_HUMAN	Q13224	CHEMBL1904	Glutamate [NMDA] Receptor Subunit Epsilon 2, Human	1
NMDE3_HUMAN	Q14957	CHEMBL4109	Glutamate [NMDA] Receptor Subunit Epsilon 3, Human	1
NMDE4_HUMAN	O15399	CHEMBL2591	Glutamate [NMDA] Receptor Subunit Epsilon 4, Human	1
NMDZ1_HUMAN	Q05586	CHEMBL2015	Glutamate (NMDA) Receptor Subunit Zeta 1, Human	1
PDYN_HUMAN	P01213	CHEMBL2227	Proenkephalin B, Human	1
Q63380_RAT	Q63380	CHEMBL6184	Transporter, Rat	1
Q9WTR4_RAT	Q9WTR4	CHEMBL304	Norepinephrine Transporter, Rat	1
SC6A2_HUMAN	P23975	CHEMBL222	Norepinephrine Transporter, Human	1
SC6A3_HUMAN	Q01959	CHEMBL238	Dopamine Transporter, Human	1
SC6A3_RAT	P23977	CHEMBL338	Dopamine Transporter, Rat	1
SC6A4_HUMAN	P31645	CHEMBL228	Serotonin Transporter, Human	1
SC6A4_RAT	P31652	CHEMBL313	Serotonin Transporter, Rat	1
UR2R_HUMAN	Q9UKP6	CHEMBL3764	Urotensin II Receptor, Human	1
Z100254	Z100254	CHEMBL613295	Monoclonal Antibody (mAb) 3E7	1
Z50425	Z50425	CHEMBL364	Plasmodium Falciparum	1
Z50594	Z50594	CHEMBL375	Mus Musculus	1