ZINC 12

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Quick Search ZINC ID or SMILES

Names
Compounds (339)
Reactome (4)
Related By:
Pathway (3)
Organism (5)
Gene (0)
Org. Clust. (3)
ChEMBL (50)
Rings (23)

Mu Opioid Receptor, Mouse (339 Compounds)

Swissprot:: OPRM_MOUSE
Stitch:: OPRM_MOUSE
UniProt:: P42866
ChEMBL:: CHEMBL2858
Reactome:: REACT_250376; REACT_205726; REACT_242845; REACT_235286
PDB:: Oprm1

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	339	22	14	17
Binding ≤ 1μM	291	16	11	14
Functional ≤ 10μM	43	5	5	2

Reactome ID	Description	Species
REACT_250376	G alpha (i) signalling events	Mus musculus
REACT_205726	G-protein activation	Mus musculus
REACT_242845	Opioid Signalling	Mus musculus
REACT_235286	Peptide ligand-binding receptors	Mus musculus

Uniprot	Swissprot	Chembl	Description	Number Shared
OPRD_MOUSE	P32300	CHEMBL3222	Delta Opioid Receptor, Mouse	186
OPRK_MOUSE	P33534	CHEMBL4329	Kappa Opioid Receptor, Mouse	103

Peptide ligand-binding receptors

Uniprot	Swissprot	Chembl	Description	Number Shared
OPRD_MOUSE	P32300	CHEMBL3222	Delta Opioid Receptor, Mouse	186
OPRK_MOUSE	P33534	CHEMBL4329	Kappa Opioid Receptor, Mouse	103

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
OPRM_BOVIN	P79350	CHEMBL3041	Mu Opioid Receptor, Bovin	76	5	4	4
OPRM_CAVPO	P97266	CHEMBL4354	Mu Opioid Receptor, Guinea Pig	210	18	14	17
OPRM_HUMAN	P35372	CHEMBL233	Mu Opioid Receptor, Human	3,374	106	57	62
OPRM_MACMU	Q9MYW9	CHEMBL5799	Mu-type Opioid Receptor, Macmu	1	1	0	1
OPRM_RAT	P33535	CHEMBL270	Mu Opioid Receptor, Rat	2,468	93	54	72

Clustered By Gene (0)

Clustered By Organism (3)

Code	Description	Substances	Purchasable	Natural	In Man
OPRM-1-E	Mu-type Opioid Receptor (cluster #1 Of 4), Eukaryotic	5,942	174	92	117
OPRM-2-E	Mu-type Opioid Receptor (cluster #2 Of 4), Eukaryotic	1	0	1	1
OPRM-3-E	Mu-type Opioid Receptor (cluster #3 Of 4), Eukaryotic	40	0	0	0
OPRM-4-E	Mu-type Opioid Receptor (cluster #4 Of 4), Eukaryotic	184	7	2	3

Uniprot	Swissprot	Chembl	Description	Number Shared
OPRD_PIG	P79291	CHEMBL4103	Delta Opioid Receptor, Pig	182
OPRD_MOUSE	P32300	CHEMBL3222	Delta Opioid Receptor, Mouse	179
OPRM_RAT	P33535	CHEMBL270	Mu Opioid Receptor, Rat	118
OPRD_RAT	P33533	CHEMBL269	Delta Opioid Receptor, Rat	107
OPRK_MOUSE	P33534	CHEMBL4329	Kappa Opioid Receptor, Mouse	103
OPRM_HUMAN	P35372	CHEMBL233	Mu Opioid Receptor, Human	90
OPRD_HUMAN	P41143	CHEMBL236	Delta Opioid Receptor, Human	83
SGMR1_MOUSE	O55242	CHEMBL3465	Sigma Opioid Receptor, Mouse	68
OPRK_HUMAN	P41145	CHEMBL237	Kappa Opioid Receptor, Human	63
OPRK_CAVPO	P41144	CHEMBL3952	Kappa Opioid Receptor, Guinea Pig	53
OPRK_RAT	P34975	CHEMBL3614	Kappa Opioid Receptor, Rat	20
Z100491	Z100491	CHEMBL613288	Sigma 2 Receptor	20
SGMR1_RAT	Q9R0C9	CHEMBL3602	Sigma Opioid Receptor, Rat	19
OPRM_CAVPO	P97266	CHEMBL4354	Mu Opioid Receptor, Guinea Pig	13
SGMR1_HUMAN	Q99720	CHEMBL287	Sigma Opioid Receptor, Human	7
OPRM_BOVIN	P79350	CHEMBL3041	Mu Opioid Receptor, Bovin	6
Z50512	Z50512	CHEMBL369	Cavia Porcellus	6
Z50594	Z50594	CHEMBL375	Mus Musculus	6
Z50597	Z50597	CHEMBL376	Rattus Norvegicus	5
NMD3B_RAT	Q8VHN2	CHEMBL282	Glutamate [NMDA] Receptor Subunit 3B, Rat	3
NMDE2_RAT	Q00960	CHEMBL311	Glutamate [NMDA] Receptor Subunit Epsilon 2, Rat	3
NMDE3_RAT	Q00961	CHEMBL401	Glutamate [NMDA] Receptor Subunit Epsilon 3, Rat	3
NMDE4_RAT	Q62645	CHEMBL303	Glutamate [NMDA] Receptor Subunit Epsilon 4, Rat	3
OPRX_HUMAN	P41146	CHEMBL2014	Nociceptin Receptor, Human	3
NMD3A_HUMAN	Q8TCU5	CHEMBL4787	Glutamate [NMDA] Receptor Subunit 3A, Human	2
NMD3B_HUMAN	O60391	CHEMBL2913	Glutamate [NMDA] Receptor Subunit 3B, Human	2
NMDE1_HUMAN	Q12879	CHEMBL1972	Glutamate [NMDA] Receptor Subunit Epsilon 1, Human	2
NMDE2_HUMAN	Q13224	CHEMBL1904	Glutamate [NMDA] Receptor Subunit Epsilon 2, Human	2
NMDE3_HUMAN	Q14957	CHEMBL4109	Glutamate [NMDA] Receptor Subunit Epsilon 3, Human	2
NMDE4_HUMAN	O15399	CHEMBL2591	Glutamate [NMDA] Receptor Subunit Epsilon 4, Human	2
NMDZ1_HUMAN	Q05586	CHEMBL2015	Glutamate (NMDA) Receptor Subunit Zeta 1, Human	2
SC6A4_RAT	P31652	CHEMBL313	Serotonin Transporter, Rat	2
Z104302	Z104302	CHEMBL1907608	Glutamate NMDA Receptor	2
ADA2A_HUMAN	P08913	CHEMBL1867	Alpha-2a Adrenergic Receptor, Human	1
KCNH2_HUMAN	Q12809	CHEMBL240	HERG, Human	1
NK1R_RAT	P14600	CHEMBL4027	Neurokinin 1 Receptor, Rat	1
PDYN_HUMAN	P01213	CHEMBL2227	Proenkephalin B, Human	1
Q63380_RAT	Q63380	CHEMBL6184	Transporter, Rat	1
Q8CGM4_CAVPO	Q8CGM4	CHEMBL5430	Mu-opioid Receptor, Guinea Pig	1
Q9WTR4_RAT	Q9WTR4	CHEMBL304	Norepinephrine Transporter, Rat	1
SC6A2_HUMAN	P23975	CHEMBL222	Norepinephrine Transporter, Human	1
SC6A3_HUMAN	Q01959	CHEMBL238	Dopamine Transporter, Human	1
SC6A3_RAT	P23977	CHEMBL338	Dopamine Transporter, Rat	1
SC6A4_HUMAN	P31645	CHEMBL228	Serotonin Transporter, Human	1
SCN1A_RAT	P04774	CHEMBL4906	Sodium Channel Protein Type I Alpha Subunit, Rat	1
SCN2A_RAT	P04775	CHEMBL3399	Sodium Channel Protein Type II Alpha Subunit, Rat	1
SCN3A_RAT	P08104	CHEMBL4966	Sodium Channel Protein Type III Alpha Subunit, Rat	1
SCN8A_RAT	O88420	CHEMBL2752	Sodium Channel Protein Type VIII Alpha Subunit, Rat	1
SGMR1_CAVPO	Q60492	CHEMBL4153	Sigma-1 Receptor, Guinea Pig	1
Z100254	Z100254	CHEMBL613295	Monoclonal Antibody (mAb) 3E7	1