UCSF

Neurokinin 1 Receptor, Rat (143 Compounds)

Swissprot:
NK1R_RAT
Stitch:
NK1R_RAT
UniProt:
P14600
ChEMBL:
CHEMBL4027
Reactome:
REACT_263374
REACT_252978
PDB:
Tacr1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 143 7 2 2
Binding ≤ 1μM 104 6 1 1
Functional ≤ 10μM 13 1 0 0

Reactome Network (2)

Reactome ID Description Species
REACT_263374 G alpha (q) signalling events Rattus norvegicus
REACT_252978 Tachykinin receptors bind tachykinins Rattus norvegicus
Uniprot Swissprot Chembl Description Number Shared
NK2R_RAT P16610 CHEMBL4554 Neurokinin 2 Receptor, Rat 9
NK3R_RAT P16177 CHEMBL3154 Neurokinin 3 Receptor, Rat 1

Tachykinin receptors bind tachykinins

Uniprot Swissprot Chembl Description Number Shared
NK2R_RAT P16610 CHEMBL4554 Neurokinin 2 Receptor, Rat 9
NK3R_RAT P16177 CHEMBL3154 Neurokinin 3 Receptor, Rat 1
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
NK1R_CAVPO P30547 CHEMBL3942 Neurokinin 1 Receptor, Guinea Pig 14 0 0 0
NK1R_HUMAN P25103 CHEMBL249 Neurokinin 1 Receptor, Human 2,709 27 6 9
NK1R_MOUSE P30548 CHEMBL2668 Neurokinin 1 Receptor, Mouse 5 2 0 0

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
NK1R-1-E Neurokinin 1 Receptor (cluster #1 Of 2), Eukaryotic 2,607 35 10 12
NK1R-2-E Neurokinin 1 Receptor (cluster #2 Of 2), Eukaryotic 292 3 0 0
Uniprot Swissprot Chembl Description Number Shared
NK1R_HUMAN P25103 CHEMBL249 Neurokinin 1 Receptor, Human 47
NK2R_RAT P16610 CHEMBL4554 Neurokinin 2 Receptor, Rat 9
NK2R_HUMAN P21452 CHEMBL2327 Neurokinin 2 Receptor, Human 7
NK1R_MOUSE P30548 CHEMBL2668 Neurokinin 1 Receptor, Mouse 5
OPRM_RAT P33535 CHEMBL270 Mu Opioid Receptor, Rat 3
CAC1F_HUMAN O60840 CHEMBL5593 Voltage-gated L-type Calcium Channel Alpha-1F Subunit, Human 2
CAC1S_HUMAN Q13698 CHEMBL3805 Voltage-gated L-type Calcium Channel Alpha-1S Subunit, Human 2
OPRM_HUMAN P35372 CHEMBL233 Mu Opioid Receptor, Human 2
Z50594 Z50594 CHEMBL375 Mus Musculus 2
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 2
CAC1C_HUMAN Q13936 CHEMBL1940 Voltage-gated L-type Calcium Channel Alpha-1C Subunit, Human 1
CAC1D_HUMAN Q01668 CHEMBL4138 Voltage-gated L-type Calcium Channel Alpha-1D Subunit, Human 1
CAC1S_RAT Q02485 CHEMBL4108 Voltage-gated L-type Calcium Channel Alpha-1S Subunit, Rat 1
NK2R_BOVIN P05363 CHEMBL4815 Neurokinin 2 Receptor, Bovin 1
NK3R_HUMAN P29371 CHEMBL4429 Neurokinin 3 Receptor, Human 1
NK3R_RAT P16177 CHEMBL3154 Neurokinin 3 Receptor, Rat 1
OPRD_HUMAN P41143 CHEMBL236 Delta Opioid Receptor, Human 1
OPRD_MOUSE P32300 CHEMBL3222 Delta Opioid Receptor, Mouse 1
OPRD_PIG P79291 CHEMBL4103 Delta Opioid Receptor, Pig 1
OPRD_RAT P33533 CHEMBL269 Delta Opioid Receptor, Rat 1
OPRK_HUMAN P41145 CHEMBL237 Kappa Opioid Receptor, Human 1
OPRK_RAT P34975 CHEMBL3614 Kappa Opioid Receptor, Rat 1
OPRM_CAVPO P97266 CHEMBL4354 Mu Opioid Receptor, Guinea Pig 1
OPRM_MOUSE P42866 CHEMBL2858 Mu Opioid Receptor, Mouse 1
Z50425 Z50425 CHEMBL364 Plasmodium Falciparum 1

Most Common Rings