UCSF

Neurokinin 3 Receptor, Human (579 Compounds)

Swissprot:
NK3R_HUMAN
Stitch:
NK3R_HUMAN
UniProt:
P29371
ChEMBL:
CHEMBL4429
Reactome:
REACT_18283
REACT_16963
PDB:
TACR3

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 579 25 2 5
Binding ≤ 1μM 475 14 2 5
Functional ≤ 10μM 110 12 1 1

Reactome Network (2)

Reactome ID Description Species
REACT_18283 G alpha (q) signalling events Homo sapiens
REACT_16963 Tachykinin receptors bind tachykinins Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
HRH1_HUMAN P35367 CHEMBL231 Histamine H1 Receptor, Human 1
NK1R_HUMAN P25103 CHEMBL249 Neurokinin 1 Receptor, Human 119
NK2R_HUMAN P21452 CHEMBL2327 Neurokinin 2 Receptor, Human 110

Tachykinin receptors bind tachykinins

Uniprot Swissprot Chembl Description Number Shared
NK1R_HUMAN P25103 CHEMBL249 Neurokinin 1 Receptor, Human 119
NK2R_HUMAN P21452 CHEMBL2327 Neurokinin 2 Receptor, Human 110
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
NK3R_CAVPO P30098 CHEMBL3799 Neurokinin 3 Receptor, Guinea Pig 8 0 1 2
NK3R_RAT P16177 CHEMBL3154 Neurokinin 3 Receptor, Rat 13 2 1 2

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
NK1R_HUMAN P25103 CHEMBL249 Neurokinin 1 Receptor, Human 119
NK2R_HUMAN P21452 CHEMBL2327 Neurokinin 2 Receptor, Human 110
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 16
OPRM_HUMAN P35372 CHEMBL233 Mu Opioid Receptor, Human 12
NK3R_RAT P16177 CHEMBL3154 Neurokinin 3 Receptor, Rat 11
NK3R_CAVPO P30098 CHEMBL3799 Neurokinin 3 Receptor, Guinea Pig 8
NK2R_BOVIN P05363 CHEMBL4815 Neurokinin 2 Receptor, Bovin 3
Z50512 Z50512 CHEMBL369 Cavia Porcellus 3
CCR5_HUMAN P51681 CHEMBL274 C-C Chemokine Receptor Type 5, Human 2
NK2R_RAT P16610 CHEMBL4554 Neurokinin 2 Receptor, Rat 2
HRH1_HUMAN P35367 CHEMBL231 Histamine H1 Receptor, Human 1
NK1R_CAVPO P30547 CHEMBL3942 Neurokinin 1 Receptor, Guinea Pig 1
NK1R_RAT P14600 CHEMBL4027 Neurokinin 1 Receptor, Rat 1
NK2R_CAVPO Q64077 CHEMBL2647 Neurokinin 2 Receptor, Guinea Pig 1
NK2R_MOUSE P30549 CHEMBL2813 Neurokinin 2 Receptor, Mouse 1
Z50593 Z50593 CHEMBL612671 Gerbillinae 1
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 1

Most Common Rings