UCSF

Glutamate [NMDA] Receptor Subunit Epsilon 2, Rat (473 Compounds)

Swissprot:
NMDE2_RAT
Stitch:
NMDE2_RAT
UniProt:
Q00960
ChEMBL:
CHEMBL311
PDB:
3JPW (DOCK)
3JPY (DOCK)
3QEL (DOCK)
3QEM (DOCK)
Grin2b

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 473 39 15 17
Binding ≤ 1μM 417 36 13 14
Functional ≤ 10μM 150 22 7 9

Reactome Network (0)

UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
NMDE2_HUMAN Q13224 CHEMBL1904 Glutamate [NMDA] Receptor Subunit Epsilon 2, Human 437 60 22 20
NMDE2_MOUSE Q01097 CHEMBL3442 Glutamate [NMDA] Receptor Subunit Epsilon 2, Mouse 16 7 4 3
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
NMDE1_RAT Q00959 CHEMBL310 Glutamate [NMDA] Receptor Subunit Epsilon 1, Rat 139 16 6 5
NMDE3_RAT Q00961 CHEMBL401 Glutamate [NMDA] Receptor Subunit Epsilon 3, Rat 245 35 12 13
NMDE4_RAT Q62645 CHEMBL303 Glutamate [NMDA] Receptor Subunit Epsilon 4, Rat 163 25 10 12

Clustered By Gene (0)

Clustered By Organism (4)

Code Description Substances Purchasable Natural In Man
NMDE2-1-E Glutamate [NMDA] Receptor Subunit Epsilon 2 (cluster #1 Of 5), Eukaryotic 622 48 20 25
NMDE2-2-E Glutamate [NMDA] Receptor Subunit Epsilon 2 (cluster #2 Of 5), Eukaryotic 33 6 1 2
NMDE2-3-E Glutamate [NMDA] Receptor Subunit Epsilon 2 (cluster #3 Of 5), Eukaryotic 89 10 2 1
NMDE2-4-E Glutamate [NMDA] Receptor Subunit Epsilon 2 (cluster #4 Of 5), Eukaryotic 44 17 7 3
NMDE2-5-E Glutamate [NMDA] Receptor Subunit Epsilon 2 (cluster #5 Of 5), Eukaryotic 83 8 2 1
Uniprot Swissprot Chembl Description Number Shared
NMDZ1_RAT P35439 CHEMBL330 Glutamate (NMDA) Receptor Subunit Zeta 1, Rat 307
NMD3B_RAT Q8VHN2 CHEMBL282 Glutamate [NMDA] Receptor Subunit 3B, Rat 177
NMDE4_RAT Q62645 CHEMBL303 Glutamate [NMDA] Receptor Subunit Epsilon 4, Rat 170
NMDE3_RAT Q00961 CHEMBL401 Glutamate [NMDA] Receptor Subunit Epsilon 3, Rat 169
NMDE1_RAT Q00959 CHEMBL310 Glutamate [NMDA] Receptor Subunit Epsilon 1, Rat 136
NMD3A_RAT Q9R1M7 CHEMBL342 Glutamate [NMDA] Receptor Subunit 3A, Rat 121
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 60
NMDZ1_HUMAN Q05586 CHEMBL2015 Glutamate (NMDA) Receptor Subunit Zeta 1, Human 57
NMDE2_HUMAN Q13224 CHEMBL1904 Glutamate [NMDA] Receptor Subunit Epsilon 2, Human 56
NMD3A_HUMAN Q8TCU5 CHEMBL4787 Glutamate [NMDA] Receptor Subunit 3A, Human 55
NMD3B_HUMAN O60391 CHEMBL2913 Glutamate [NMDA] Receptor Subunit 3B, Human 55
NMDE1_HUMAN Q12879 CHEMBL1972 Glutamate [NMDA] Receptor Subunit Epsilon 1, Human 55
NMDE3_HUMAN Q14957 CHEMBL4109 Glutamate [NMDA] Receptor Subunit Epsilon 3, Human 55
NMDE4_HUMAN O15399 CHEMBL2591 Glutamate [NMDA] Receptor Subunit Epsilon 4, Human 55
GRINA_HUMAN Q7Z429 CHEMBL4704 Glutamate [NMDA] Receptor Associated Protein 1, Human 40
GRIA1_MOUSE P23818 CHEMBL3502 Glutamate Receptor Ionotropic, AMPA 1, Mouse 38
GRIA2_RAT P19491 CHEMBL3503 Glutamate Receptor Ionotropic, AMPA 2, Rat 38
GRIA3_RAT P19492 CHEMBL3504 Glutamate Receptor Ionotropic, AMPA 3, Rat 38
GRIA4_RAT P19493 CHEMBL3505 Glutamate Receptor Ionotropic, AMPA 4, Rat 38
Z104302 Z104302 CHEMBL1907608 Glutamate NMDA Receptor 33
OPRM_RAT P33535 CHEMBL270 Mu Opioid Receptor, Rat 29
Z104304 Z104304 CHEMBL1907610 Adrenergic Receptor Alpha-1 27
Z104297 Z104297 CHEMBL1907603 Glutamate NMDA Receptor; GRIN1/GRIN2B 18
GRL1A_RAT Q91XQ4 CHEMBL3059 Glutamate [NMDA] Receptor-like 1A, Rat 13
ACM1_RAT P08482 CHEMBL276 Muscarinic Acetylcholine Receptor M1, Rat 12
SGMR1_HUMAN Q99720 CHEMBL287 Sigma Opioid Receptor, Human 9
SGMR1_RAT Q9R0C9 CHEMBL3602 Sigma Opioid Receptor, Rat 8
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 7
A2AIR5_MOUSE A2AIR5 CHEMBL2562 Glutamate [NMDA] Receptor Subunit 3A, Mouse 6
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 6
NMD3B_MOUSE Q91ZU9 CHEMBL2557 Glutamate [NMDA] Receptor Subunit 3B, Mouse 6
NMDE1_MOUSE P35436 CHEMBL2521 Glutamate [NMDA] Receptor Subunit Epsilon 1, Mouse 6
NMDE2_MOUSE Q01097 CHEMBL3442 Glutamate [NMDA] Receptor Subunit Epsilon 2, Mouse 6
NMDE3_MOUSE Q01098 CHEMBL3555 Glutamate [NMDA] Receptor Subunit Epsilon 3, Mouse 6
NMDE4_MOUSE Q03391 CHEMBL2893 Glutamate [NMDA] Receptor Subunit Epsilon 4, Mouse 6
NMDZ1_MOUSE P35438 CHEMBL2895 Glutamate (NMDA) Receptor Subunit Zeta 1, Mouse 6
Z100491 Z100491 CHEMBL613288 Sigma 2 Receptor 6
Z50425 Z50425 CHEMBL364 Plasmodium Falciparum 6
OPRK_HUMAN P41145 CHEMBL237 Kappa Opioid Receptor, Human 5
OPRD_HUMAN P41143 CHEMBL236 Delta Opioid Receptor, Human 4
OPRD_RAT P33533 CHEMBL269 Delta Opioid Receptor, Rat 4
OPRK_RAT P34975 CHEMBL3614 Kappa Opioid Receptor, Rat 4
OPRM_HUMAN P35372 CHEMBL233 Mu Opioid Receptor, Human 4
ADA1A_HUMAN P35348 CHEMBL229 Alpha-1a Adrenergic Receptor, Human 3
GRIA1_HUMAN P42261 CHEMBL2009 Glutamate Receptor Ionotropic, AMPA 1, Human 3
GRIA2_HUMAN P42262 CHEMBL4016 Glutamate Receptor Ionotropic, AMPA 2, Human 3
GRIA4_HUMAN P48058 CHEMBL3190 Glutamate Receptor Ionotropic, AMPA 4, Human 3
OPRK_CAVPO P41144 CHEMBL3952 Kappa Opioid Receptor, Guinea Pig 3
OPRM_CAVPO P97266 CHEMBL4354 Mu Opioid Receptor, Guinea Pig 3
OPRM_MOUSE P42866 CHEMBL2858 Mu Opioid Receptor, Mouse 3
SGMR1_CAVPO Q60492 CHEMBL4153 Sigma-1 Receptor, Guinea Pig 3
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 2
ADA1B_HUMAN P35368 CHEMBL232 Alpha-1b Adrenergic Receptor, Human 2
ADA1D_HUMAN P25100 CHEMBL223 Alpha-1d Adrenergic Receptor, Human 2
ADA2A_RAT P22909 CHEMBL327 Alpha-2a Adrenergic Receptor, Rat 2
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 2
GRIA1_RAT P19490 CHEMBL3753 Glutamate Receptor Ionotropic, AMPA 1, Rat 2
GRIA3_HUMAN P42263 CHEMBL3595 Glutamate Receptor Ionotropic, AMPA 3, Human 2
GRIK1_HUMAN P39086 CHEMBL1918 Glutamate Receptor Ionotropic Kainate 1, Human 2
GRIK1_RAT P22756 CHEMBL2919 Glutamate Receptor Ionotropic Kainate 1, Rat 2
GRIK2_HUMAN Q13002 CHEMBL3683 Glutamate Receptor Ionotropic Kainate 2, Human 2
GRIK2_RAT P42260 CHEMBL3607 Glutamate Receptor Ionotropic Kainate 2, Rat 2
GRIK3_HUMAN Q13003 CHEMBL3684 Glutamate Receptor Ionotropic Kainate 3, Human 2
GRIK3_RAT P42264 CHEMBL3744 Glutamate Receptor Ionotropic Kainate 3, Rat 2
GRIK4_RAT Q01812 CHEMBL3044 Glutamate Receptor Ionotropic Kainate 4, Rat 2
GRIK5_HUMAN Q16478 CHEMBL2675 Glutamate Receptor Ionotropic Kainate 5, Human 2
GRIK5_RAT Q63273 CHEMBL4041 Glutamate Receptor Ionotropic Kainate 5, Rat 2
OPRD_MOUSE P32300 CHEMBL3222 Delta Opioid Receptor, Mouse 2
OPRK_MOUSE P33534 CHEMBL4329 Kappa Opioid Receptor, Mouse 2
Z104298 Z104298 CHEMBL1907604 Glutamate NMDA Receptor; GRIN1/GRIN2A 2
Z50594 Z50594 CHEMBL375 Mus Musculus 2
Z80951 Z80951 CHEMBL614822 NIH3T3 (Fibroblasts) 2
5HT1A_MOUSE Q64264 CHEMBL3737 Serotonin 1a (5-HT1a) Receptor, Mouse 1
5HT2A_BOVIN Q75Z89 CHEMBL3446 Serotonin 2a (5-HT2a) Receptor, Bovin 1
ACM1_HUMAN P11229 CHEMBL216 Muscarinic Acetylcholine Receptor M1, Human 1
ACM2_RAT P10980 CHEMBL309 Muscarinic Acetylcholine Receptor M2, Rat 1
ADA2B_RAT P19328 CHEMBL266 Alpha-2b Adrenergic Receptor, Rat 1
ADA2C_RAT P22086 CHEMBL314 Alpha-2c Adrenergic Receptor, Rat 1
DRD2_BOVIN P20288 CHEMBL3998 Dopamine D2 Receptor, Bovin 1
EBP_CAVPO Q60490 CHEMBL5525 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase, Guinea Pig 1
EBP_HUMAN Q15125 CHEMBL4931 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase, Human 1
ERG2_YEAST P32352 CHEMBL3224 C-8 Sterol Isomerase, Yeast 1
GRIK4_HUMAN Q16099 CHEMBL2829 Glutamate Receptor Ionotropic Kainate 4, Human 1
GRM1_HUMAN Q13255 CHEMBL3772 Metabotropic Glutamate Receptor 1, Human 1
GRM1_RAT P23385 CHEMBL4477 Metabotropic Glutamate Receptor 1, Rat 1
GRM2_HUMAN Q14416 CHEMBL5137 Metabotropic Glutamate Receptor 2, Human 1
GRM2_RAT P31421 CHEMBL2851 Metabotropic Glutamate Receptor 2, Rat 1
GRM3_HUMAN Q14832 CHEMBL2888 Metabotropic Glutamate Receptor 3, Human 1
GRM3_RAT P31422 CHEMBL3067 Metabotropic Glutamate Receptor 3, Rat 1
GRM4_HUMAN Q14833 CHEMBL2736 Metabotropic Glutamate Receptor 4, Human 1
GRM5_HUMAN P41594 CHEMBL3227 Metabotropic Glutamate Receptor 5, Human 1
GRM5_RAT P31424 CHEMBL2564 Metabotropic Glutamate Receptor 5, Rat 1
GRM6_HUMAN O15303 CHEMBL4573 Metabotropic Glutamate Receptor 6, Human 1
HRH1_HUMAN P35367 CHEMBL231 Histamine H1 Receptor, Human 1
MURI_HELPY P56068 CHEMBL6078 Glutamate Racemase, Helpy 1
PCP_HUMAN P42785 CHEMBL2335 Lysosomal Pro-X Carboxypeptidase, Human 1
SGMR1_MOUSE O55242 CHEMBL3465 Sigma Opioid Receptor, Mouse 1
Z50587 Z50587 CHEMBL372 Homo Sapiens 1
Z80390 Z80390 CHEMBL390 PC-3 (Prostate Carcinoma Cells) 1

Most Common Rings