UCSF

Glutamate Receptor Ionotropic, AMPA 4, Rat (657 Compounds)

Swissprot:
GRIA4_RAT
Stitch:
GRIA4_RAT
UniProt:
P19493
ChEMBL:
CHEMBL3505
PDB:
3EN3 (DOCK)
3EPE (DOCK)
3FAS (DOCK)
3FAT (DOCK)
3KEI (DOCK)
3KFM (DOCK)
Gria4

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 657 37 21 25
Binding ≤ 1μM 373 22 15 18
Functional ≤ 10μM 156 20 9 6

Reactome Network (0)

UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
GRIA4_HUMAN P48058 CHEMBL3190 Glutamate Receptor Ionotropic, AMPA 4, Human 122 18 13 13
GRIA4_MOUSE Q9Z2W8 CHEMBL3615 Glutamate Receptor Ionotropic, AMPA 4, Mouse 25 5 4 3
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
GRIA1_RAT P19490 CHEMBL3753 Glutamate Receptor Ionotropic, AMPA 1, Rat 154 22 15 17
GRIA2_RAT P19491 CHEMBL3503 Glutamate Receptor Ionotropic, AMPA 2, Rat 671 39 21 25
GRIA3_RAT P19492 CHEMBL3504 Glutamate Receptor Ionotropic, AMPA 3, Rat 666 37 21 25

Clustered By Gene (0)

Clustered By Organism (4)

Code Description Substances Purchasable Natural In Man
GRIA4-1-E Glutamate Receptor Ionotropic, AMPA 4 (cluster #1 Of 5), Eukaryotic 623 17 7 6
GRIA4-2-E Glutamate Receptor Ionotropic, AMPA 4 (cluster #2 Of 5), Eukaryotic 13 4 1 1
GRIA4-3-E Glutamate Receptor Ionotropic, AMPA 4 (cluster #3 Of 5), Eukaryotic 51 4 5 4
GRIA4-4-E Glutamate Receptor Ionotropic, AMPA 4 (cluster #4 Of 5), Eukaryotic 58 20 10 20
GRIA4-5-E Glutamate Receptor Ionotropic, AMPA 4 (cluster #5 Of 5), Eukaryotic 23 1 3 1
Uniprot Swissprot Chembl Description Number Shared
GRIA3_RAT P19492 CHEMBL3504 Glutamate Receptor Ionotropic, AMPA 3, Rat 767
GRIA2_RAT P19491 CHEMBL3503 Glutamate Receptor Ionotropic, AMPA 2, Rat 766
GRIA1_MOUSE P23818 CHEMBL3502 Glutamate Receptor Ionotropic, AMPA 1, Mouse 589
GRIA1_RAT P19490 CHEMBL3753 Glutamate Receptor Ionotropic, AMPA 1, Rat 222
Z104302 Z104302 CHEMBL1907608 Glutamate NMDA Receptor 168
NMDZ1_RAT P35439 CHEMBL330 Glutamate (NMDA) Receptor Subunit Zeta 1, Rat 152
GRIK1_RAT P22756 CHEMBL2919 Glutamate Receptor Ionotropic Kainate 1, Rat 86
GRIK3_RAT P42264 CHEMBL3744 Glutamate Receptor Ionotropic Kainate 3, Rat 70
GRIK4_RAT Q01812 CHEMBL3044 Glutamate Receptor Ionotropic Kainate 4, Rat 69
GRIK5_RAT Q63273 CHEMBL4041 Glutamate Receptor Ionotropic Kainate 5, Rat 69
GRIK2_RAT P42260 CHEMBL3607 Glutamate Receptor Ionotropic Kainate 2, Rat 68
GRIA1_HUMAN P42261 CHEMBL2009 Glutamate Receptor Ionotropic, AMPA 1, Human 38
NMD3A_RAT Q9R1M7 CHEMBL342 Glutamate [NMDA] Receptor Subunit 3A, Rat 38
NMD3B_RAT Q8VHN2 CHEMBL282 Glutamate [NMDA] Receptor Subunit 3B, Rat 38
NMDE1_RAT Q00959 CHEMBL310 Glutamate [NMDA] Receptor Subunit Epsilon 1, Rat 38
NMDE2_RAT Q00960 CHEMBL311 Glutamate [NMDA] Receptor Subunit Epsilon 2, Rat 38
NMDE4_RAT Q62645 CHEMBL303 Glutamate [NMDA] Receptor Subunit Epsilon 4, Rat 38
GRIA4_HUMAN P48058 CHEMBL3190 Glutamate Receptor Ionotropic, AMPA 4, Human 37
NMDE3_RAT Q00961 CHEMBL401 Glutamate [NMDA] Receptor Subunit Epsilon 3, Rat 36
GRIA2_HUMAN P42262 CHEMBL4016 Glutamate Receptor Ionotropic, AMPA 2, Human 35
GRIA3_HUMAN P42263 CHEMBL3595 Glutamate Receptor Ionotropic, AMPA 3, Human 28
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 20
GRIK5_HUMAN Q16478 CHEMBL2675 Glutamate Receptor Ionotropic Kainate 5, Human 17
GRIK1_HUMAN P39086 CHEMBL1918 Glutamate Receptor Ionotropic Kainate 1, Human 16
GRIK2_HUMAN Q13002 CHEMBL3683 Glutamate Receptor Ionotropic Kainate 2, Human 8
NMDZ1_HUMAN Q05586 CHEMBL2015 Glutamate (NMDA) Receptor Subunit Zeta 1, Human 8
GRIA2_MOUSE P23819 CHEMBL3205 Glutamate Receptor Ionotropic, AMPA 2, Mouse 7
GRIA3_MOUSE Q9Z2W9 CHEMBL3624 Glutamate Receptor Ionotropic, AMPA 3, Mouse 7
GRIA4_MOUSE Q9Z2W8 CHEMBL3615 Glutamate Receptor Ionotropic, AMPA 4, Mouse 7
GRIK3_HUMAN Q13003 CHEMBL3684 Glutamate Receptor Ionotropic Kainate 3, Human 7
GRIK4_HUMAN Q16099 CHEMBL2829 Glutamate Receptor Ionotropic Kainate 4, Human 5
GRM8_MOUSE P47743 CHEMBL4626 Metabotropic Glutamate Receptor 8, Mouse 5
NMD3A_HUMAN Q8TCU5 CHEMBL4787 Glutamate [NMDA] Receptor Subunit 3A, Human 5
NMD3B_HUMAN O60391 CHEMBL2913 Glutamate [NMDA] Receptor Subunit 3B, Human 5
NMDE1_HUMAN Q12879 CHEMBL1972 Glutamate [NMDA] Receptor Subunit Epsilon 1, Human 5
NMDE2_HUMAN Q13224 CHEMBL1904 Glutamate [NMDA] Receptor Subunit Epsilon 2, Human 5
NMDE3_HUMAN Q14957 CHEMBL4109 Glutamate [NMDA] Receptor Subunit Epsilon 3, Human 5
NMDE4_HUMAN O15399 CHEMBL2591 Glutamate [NMDA] Receptor Subunit Epsilon 4, Human 5
GLRA1_RAT P07727 CHEMBL3246 Glycine Receptor Alpha-1 Chain, Rat 4
GLRA2_RAT P22771 CHEMBL2328 Glycine Receptor Alpha-2 Chain, Rat 4
GLRA3_RAT P24524 CHEMBL2677 Glycine Receptor Alpha-3 Chain, Rat 4
GLRB_RAT P20781 CHEMBL4126 Glycine Receptor Beta Chain, Rat 4
GRM1_MOUSE P97772 CHEMBL2892 Metabotropic Glutamate Receptor 1, Mouse 4
GRM3_MOUSE Q9QYS2 CHEMBL3824 Metabotropic Glutamate Receptor 3, Mouse 4
GRM7_MOUSE Q68ED2 CHEMBL3966 Metabotropic Glutamate Receptor 7, Mouse 4
Q80T35_MOUSE Q80T35 CHEMBL3033 Metabotropic Glutamate Receptor 6, Mouse 4
Q80T43_MOUSE Q80T43 CHEMBL3779 Metabotropic Glutamate Receptor 2, Mouse 4
Q80T47_MOUSE Q80T47 CHEMBL2832 Metabotropic Glutamate Receptor 5, Mouse 4
Z50574 Z50574 CHEMBL612667 Xenopus Sp. 4
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 3
GRM1_HUMAN Q13255 CHEMBL3772 Metabotropic Glutamate Receptor 1, Human 3
GRM1_RAT P23385 CHEMBL4477 Metabotropic Glutamate Receptor 1, Rat 3
GRM5_HUMAN P41594 CHEMBL3227 Metabotropic Glutamate Receptor 5, Human 3
GRM5_RAT P31424 CHEMBL2564 Metabotropic Glutamate Receptor 5, Rat 3
GLRA4_MOUSE Q61603 CHEMBL3500 Glycine Receptor Alpha-4 Chain, Mouse 2
GRID1_HUMAN Q9ULK0 CHEMBL2936 Glutamate Receptor Delta-1 Subunit, Human 2
GRIK2_XENLA Q91755 CHEMBL3395 Glutamate Receptor Ionotropic Kainate 2, Xenla 2
GRM2_HUMAN Q14416 CHEMBL5137 Metabotropic Glutamate Receptor 2, Human 2
GRM2_RAT P31421 CHEMBL2851 Metabotropic Glutamate Receptor 2, Rat 2
GRM3_RAT P31422 CHEMBL3067 Metabotropic Glutamate Receptor 3, Rat 2
GRM4_HUMAN Q14833 CHEMBL2736 Metabotropic Glutamate Receptor 4, Human 2
GRM8_RAT P70579 CHEMBL2718 Metabotropic Glutamate Receptor 8, Rat 2
Z50425 Z50425 CHEMBL364 Plasmodium Falciparum 2
EAA3_HUMAN P43005 CHEMBL2721 Excitatory Amino Acid Transporter 3, Human 1
FOLH1_HUMAN Q04609 CHEMBL1892 Glutamate Carboxypeptidase II, Human 1
GRM3_HUMAN Q14832 CHEMBL2888 Metabotropic Glutamate Receptor 3, Human 1
GRM4_RAT P31423 CHEMBL2787 Metabotropic Glutamate Receptor 4, Rat 1
GRM6_HUMAN O15303 CHEMBL4573 Metabotropic Glutamate Receptor 6, Human 1
GRM6_RAT P35349 CHEMBL3842 Metabotropic Glutamate Receptor 6, Rat 1
GRM8_HUMAN O00222 CHEMBL3228 Metabotropic Glutamate Receptor 8, Human 1
MURI_HELPY P56068 CHEMBL6078 Glutamate Racemase, Helpy 1
XCT_HUMAN Q9UPY5 CHEMBL1075149 Cystine/glutamate Transporter, Human 1
Z50501 Z50501 CHEMBL613109 Gallus Gallus 1
Z50594 Z50594 CHEMBL375 Mus Musculus 1
Z81252 Z81252 CHEMBL400 MDA-MB-231 (Breast Adenocarcinoma Cells) 1