ZINC 12

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Quick Search ZINC ID or SMILES

Names
Compounds (96)
Reactome (0)
Related By:
Pathway (0)
Organism (1)
Gene (0)
Org. Clust. (1)
ChEMBL (77)
Rings (5)

Sodium Channel Protein Type VIII Alpha Subunit, Rat (96 Compounds)

Swissprot:: SCN8A_RAT
Stitch:: SCN8A_RAT
UniProt:: O88420
ChEMBL:: CHEMBL2752
PDB:: Scn8a

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	96	10	5	6
Binding ≤ 1μM	54	5	2	2
Functional ≤ 10μM	70	7	7	8

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
SCN8A_HUMAN	Q9UQD0	CHEMBL5202	Sodium Channel Protein Type VIII Alpha Subunit, Human	98	73	66	73

Clustered By Gene (0)

Clustered By Organism (1)

Code	Description	Substances	Purchasable	Natural	In Man
SCN8A-1-E	Sodium Channel Protein Type VIII Alpha Subunit (cluster #1 Of 2), Eukaryotic	156	63	52	58
SCN8A-2-E	Sodium Channel Protein Type VIII Alpha Subunit (cluster #2 Of 2), Eukaryotic	37	19	18	20

Uniprot	Swissprot	Chembl	Description	Number Shared
SCN1A_RAT	P04774	CHEMBL4906	Sodium Channel Protein Type I Alpha Subunit, Rat	120
SCN2A_RAT	P04775	CHEMBL3399	Sodium Channel Protein Type II Alpha Subunit, Rat	120
SCN3A_RAT	P08104	CHEMBL4966	Sodium Channel Protein Type III Alpha Subunit, Rat	120
SCN5A_HUMAN	Q14524	CHEMBL1980	Sodium Channel Protein Type V Alpha Subunit, Human	41
Z50597	Z50597	CHEMBL376	Rattus Norvegicus	27
P97706_RAT	P97706	CHEMBL4957	Sodium Channel Protein Type VI Alpha Subunit, Rat	13
SCN5A_RAT	P15389	CHEMBL3866	Sodium Channel Protein Type V Alpha Subunit, Rat	13
CAC1G_RAT	O54898	CHEMBL4257	Voltage-gated T-type Calcium Channel Alpha-1G Subunit, Rat	9
CAC1H_RAT	Q9EQ60	CHEMBL5134	Voltage-gated T-type Calcium Channel Alpha-1H Subunit, Rat	9
CAC1I_RAT	Q9Z0Y8	CHEMBL5459	Voltage-gated T-type Calcium Channel Alpha-1I Subunit, Rat	9
5HT2A_RAT	P14842	CHEMBL322	Serotonin 2a (5-HT2a) Receptor, Rat	6
5HT2B_RAT	P30994	CHEMBL323	Serotonin 2b (5-HT2b) Receptor, Rat	6
5HT2C_RAT	P08909	CHEMBL324	Serotonin 2c (5-HT2c) Receptor, Rat	6
ADA2A_RAT	P22909	CHEMBL327	Alpha-2a Adrenergic Receptor, Rat	6
ADA2B_RAT	P19328	CHEMBL266	Alpha-2b Adrenergic Receptor, Rat	6
ADA2C_RAT	P22086	CHEMBL314	Alpha-2c Adrenergic Receptor, Rat	6
SGMR1_HUMAN	Q99720	CHEMBL287	Sigma Opioid Receptor, Human	6
Z104304	Z104304	CHEMBL1907610	Adrenergic Receptor Alpha-1	6
SGMR1_RAT	Q9R0C9	CHEMBL3602	Sigma Opioid Receptor, Rat	5
5HT1A_RAT	P19327	CHEMBL273	Serotonin 1a (5-HT1a) Receptor, Rat	4
5HT1B_RAT	P28564	CHEMBL3459	Serotonin 1b (5-HT1b) Receptor, Rat	3
5HT1D_RAT	P28565	CHEMBL5450	Serotonin 1d (5-HT1d) Receptor, Rat	3
5HT1F_RAT	P30940	CHEMBL4646	Serotonin 1f (5-HT1f) Receptor, Rat	3
ADA1A_RAT	P43140	CHEMBL319	Alpha-1a Adrenergic Receptor, Rat	3
ADA1B_RAT	P15823	CHEMBL315	Alpha-1b Adrenergic Receptor, Rat	3
CCR5_HUMAN	P51681	CHEMBL274	C-C Chemokine Receptor Type 5, Human	3
DRD2_HUMAN	P14416	CHEMBL217	Dopamine D2 Receptor, Human	3
DRD3_HUMAN	P35462	CHEMBL234	Dopamine D3 Receptor, Human	3
SCN4A_RAT	P15390	CHEMBL3509	Sodium Channel Protein Type IV Alpha Subunit, Rat	3
SCN9A_RAT	O08562	CHEMBL3312	Sodium Channel Protein Type IX Alpha Subunit, Rat	3
SCNAA_RAT	Q62968	CHEMBL4017	Sodium Channel Protein Type X Alpha Subunit, Rat	3
SCNBA_RAT	O88457	CHEMBL2629	Sodium Channel Protein Type XI Alpha Subunit, Rat	3
ADA2A_HUMAN	P08913	CHEMBL1867	Alpha-2a Adrenergic Receptor, Human	2
ADA2B_HUMAN	P18089	CHEMBL1942	Alpha-2b Adrenergic Receptor, Human	2
AOFB_RAT	P19643	CHEMBL2993	Monoamine Oxidase B, Rat	2
SCN1A_HUMAN	P35498	CHEMBL1845	Sodium Channel Protein Type I Alpha Subunit, Human	2
SCN2A_HUMAN	Q99250	CHEMBL4187	Sodium Channel Protein Type II Alpha Subunit, Human	2
SCN3A_HUMAN	Q9NY46	CHEMBL5163	Sodium Channel Protein Type III Alpha Subunit, Human	2
SCN8A_HUMAN	Q9UQD0	CHEMBL5202	Sodium Channel Protein Type VIII Alpha Subunit, Human	2
Z100491	Z100491	CHEMBL613288	Sigma 2 Receptor	2
Z50466	Z50466	CHEMBL368	Trypanosoma Cruzi	2
AOFB_HUMAN	P27338	CHEMBL2039	Monoamine Oxidase B, Human	1
CA2D1_RAT	P54290	CHEMBL3420	Voltage-gated Calcium Channel Alpha2/delta Subunit 1, Rat	1
CAC1B_HUMAN	Q00975	CHEMBL4478	Voltage-gated N-type Calcium Channel Alpha-1B Subunit, Human	1
CAC1B_RAT	Q02294	CHEMBL5107	Voltage-gated N-type Calcium Channel Alpha-1B Subunit, Rat	1
CAC1C_RAT	P22002	CHEMBL3762	Voltage-gated L-type Calcium Channel Alpha-1C Subunit, Rat	1
CAC1F_HUMAN	O60840	CHEMBL5593	Voltage-gated L-type Calcium Channel Alpha-1F Subunit, Human	1
CAC1G_HUMAN	O43497	CHEMBL4641	Voltage-gated T-type Calcium Channel Alpha-1G Subunit, Human	1
CAC1H_HUMAN	O95180	CHEMBL1859	Voltage-gated T-type Calcium Channel Alpha-1H Subunit, Human	1
CAC1I_HUMAN	Q9P0X4	CHEMBL5558	Voltage-gated T-type Calcium Channel Alpha-1I Subunit, Human	1
CAC1S_HUMAN	Q13698	CHEMBL3805	Voltage-gated L-type Calcium Channel Alpha-1S Subunit, Human	1
CACB1_RAT	P54283	CHEMBL1075136	Voltage-dependent L-type Calcium Channel Subunit Beta-1, Rat	1
CNGA1_BOVIN	Q00194	CHEMBL4907	CGMP-gated Cation Channel Alpha 1, Bovin	1
DRD2_RAT	P61169	CHEMBL339	Dopamine D2 Receptor, Rat	1
DRD4_HUMAN	P21917	CHEMBL219	Dopamine D4 Receptor, Human	1
HRH1_HUMAN	P35367	CHEMBL231	Histamine H1 Receptor, Human	1
KCNH2_HUMAN	Q12809	CHEMBL240	HERG, Human	1
NMD3A_HUMAN	Q8TCU5	CHEMBL4787	Glutamate [NMDA] Receptor Subunit 3A, Human	1
NMD3B_HUMAN	O60391	CHEMBL2913	Glutamate [NMDA] Receptor Subunit 3B, Human	1
NMDE1_HUMAN	Q12879	CHEMBL1972	Glutamate [NMDA] Receptor Subunit Epsilon 1, Human	1
NMDE2_HUMAN	Q13224	CHEMBL1904	Glutamate [NMDA] Receptor Subunit Epsilon 2, Human	1
NMDE3_HUMAN	Q14957	CHEMBL4109	Glutamate [NMDA] Receptor Subunit Epsilon 3, Human	1
NMDE4_HUMAN	O15399	CHEMBL2591	Glutamate [NMDA] Receptor Subunit Epsilon 4, Human	1
NMDZ1_HUMAN	Q05586	CHEMBL2015	Glutamate (NMDA) Receptor Subunit Zeta 1, Human	1
OPRD_HUMAN	P41143	CHEMBL236	Delta Opioid Receptor, Human	1
OPRD_MOUSE	P32300	CHEMBL3222	Delta Opioid Receptor, Mouse	1
OPRK_HUMAN	P41145	CHEMBL237	Kappa Opioid Receptor, Human	1
OPRK_MOUSE	P33534	CHEMBL4329	Kappa Opioid Receptor, Mouse	1
OPRM_HUMAN	P35372	CHEMBL233	Mu Opioid Receptor, Human	1
OPRM_MOUSE	P42866	CHEMBL2858	Mu Opioid Receptor, Mouse	1
S29A1_HUMAN	Q99808	CHEMBL1997	Equilibrative Nucleoside Transporter 1, Human	1
SC6A3_HUMAN	Q01959	CHEMBL238	Dopamine Transporter, Human	1
SCN9A_HUMAN	Q15858	CHEMBL4296	Sodium Channel Protein Type IX Alpha Subunit, Human	1
SGMR1_CAVPO	Q60492	CHEMBL4153	Sigma-1 Receptor, Guinea Pig	1
SGMR1_MOUSE	O55242	CHEMBL3465	Sigma Opioid Receptor, Mouse	1
Z104302	Z104302	CHEMBL1907608	Glutamate NMDA Receptor	1
Z50425	Z50425	CHEMBL364	Plasmodium Falciparum	1