UCSF

Neuronal Acetylcholine Receptor Protein Beta-2 Subunit, Rat (331 Compounds)

Swissprot:
ACHB2_RAT
Stitch:
ACHB2_RAT
UniProt:
P12390
ChEMBL:
CHEMBL3001
Reactome:
REACT_196479
REACT_196490
PDB:
1OLE (DOCK)
1OLF (DOCK)
Chrnb2

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 331 54 17 6
Binding ≤ 1μM 269 45 13 6

Reactome Network (2)

Reactome ID Description Species
REACT_196479 Highly calcium permeable nicotinic acetylcholine receptors Rattus norvegicus
REACT_196490 Highly sodium permeable acetylcholine nicotinic receptors Rattus norvegicus
Uniprot Swissprot Chembl Description Number Shared
ACHA2_RAT P12389 CHEMBL2584 Neuronal Acetylcholine Receptor Protein Alpha-2 Subunit, Rat 300
ACHA_RAT P25108 CHEMBL3599 Acetylcholine Receptor Protein Alpha Chain, Rat 296
ACHB3_RAT P12391 CHEMBL4568 Neuronal Acetylcholine Receptor Protein Beta-3 Subunit, Rat 296
ACHB4_RAT P12392 CHEMBL2658 Neuronal Acetylcholine Receptor Protein Beta-4 Subunit, Rat 327

Highly sodium permeable acetylcholine nicotinic receptors

Uniprot Swissprot Chembl Description Number Shared
ACHB4_RAT P12392 CHEMBL2658 Neuronal Acetylcholine Receptor Protein Beta-4 Subunit, Rat 327
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
ACHB2_HUMAN P17787 CHEMBL1883 Neuronal Acetylcholine Receptor Protein Beta-2 Subunit, Human 64 13 8 7
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
ACHB3_RAT P12391 CHEMBL4568 Neuronal Acetylcholine Receptor Protein Beta-3 Subunit, Rat 296 50 13 2
ACHB4_RAT P12392 CHEMBL2658 Neuronal Acetylcholine Receptor Protein Beta-4 Subunit, Rat 370 59 16 5
ACHB_RAT P25109 CHEMBL2666 Acetylcholine Receptor Protein Beta Chain, Rat 296 50 13 2

Clustered By Gene (0)

Clustered By Organism (6)

Code Description Substances Purchasable Natural In Man
ACHB2-1-E Neuronal Acetylcholine Receptor Protein Beta-2 Subunit (cluster #1 Of 7), Eukaryotic 80 14 1 0
ACHB2-2-E Neuronal Acetylcholine Receptor Protein Beta-2 Subunit (cluster #2 Of 7), Eukaryotic 84 6 0 1
ACHB2-3-E Neuronal Acetylcholine Receptor Protein Beta-2 Subunit (cluster #3 Of 7), Eukaryotic 2 2 2 2
ACHB2-4-E Neuronal Acetylcholine Receptor Protein Beta-2 Subunit (cluster #4 Of 7), Eukaryotic 141 29 8 5
ACHB2-5-E Neuronal Acetylcholine Receptor Protein Beta-2 Subunit (cluster #5 Of 7), Eukaryotic 53 7 7 2
ACHB2-6-E Neuronal Acetylcholine Receptor Protein Beta-2 Subunit (cluster #6 Of 7), Eukaryotic 8 3 3 0
ACHB2-7-E Neuronal Acetylcholine Receptor Protein Beta-2 Subunit (cluster #7 Of 7), Eukaryotic 1 0 0 0
Uniprot Swissprot Chembl Description Number Shared
ACHB4_RAT P12392 CHEMBL2658 Neuronal Acetylcholine Receptor Protein Beta-4 Subunit, Rat 327
ACHA4_RAT P09483 CHEMBL307 Neuronal Acetylcholine Receptor Protein Alpha-4 Subunit, Rat 317
ACHA3_RAT P04757 CHEMBL3818 Neuronal Acetylcholine Receptor Protein Alpha-3 Subunit, Rat 313
ACHA7_RAT Q05941 CHEMBL4980 Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit, Rat 302
ACHA2_RAT P12389 CHEMBL2584 Neuronal Acetylcholine Receptor Protein Alpha-2 Subunit, Rat 300
ACHA9_RAT P43144 CHEMBL2585 Neuronal Acetylcholine Receptor Protein Alpha-9 Subunit, Rat 300
ACH10_RAT Q9JLB5 CHEMBL3461 Neuronal Acetylcholine Receptor Protein Alpha-10 Subunit, Rat 296
ACHA5_RAT P20420 CHEMBL4960 Neuronal Acetylcholine Receptor Protein Alpha-5 Subunit, Rat 296
ACHA6_RAT P43143 CHEMBL4747 Neuronal Acetylcholine Receptor Protein Alpha-6 Subunit, Rat 296
ACHA_RAT P25108 CHEMBL3599 Acetylcholine Receptor Protein Alpha Chain, Rat 296
ACHB3_RAT P12391 CHEMBL4568 Neuronal Acetylcholine Receptor Protein Beta-3 Subunit, Rat 296
ACHB_RAT P25109 CHEMBL2666 Acetylcholine Receptor Protein Beta Chain, Rat 296
Z104290 Z104290 CHEMBL1907596 Neuronal Acetylcholine Receptor; Alpha4/beta2 56
ACHD_TORCA P02718 CHEMBL3916 Acetylcholine Receptor Protein Delta Chain, Torca 33
ACHB2_HUMAN P17787 CHEMBL1883 Neuronal Acetylcholine Receptor Protein Beta-2 Subunit, Human 26
Z104303 Z104303 CHEMBL1907609 Muscarinic Acetylcholine Receptor 26
ACHA3_HUMAN P32297 CHEMBL3068 Neuronal Acetylcholine Receptor Protein Alpha-3 Subunit, Human 25
Z104286 Z104286 CHEMBL1907592 Neuronal Acetylcholine Receptor; Alpha2/beta2 21
Z104287 Z104287 CHEMBL1907593 Neuronal Acetylcholine Receptor; Alpha3/beta4 21
Z104289 Z104289 CHEMBL1907595 Neuronal Acetylcholine Receptor; Alpha4/beta4 19
ACHA4_HUMAN P43681 CHEMBL1882 Neuronal Acetylcholine Receptor Protein Alpha-4 Subunit, Human 18
Z104281 Z104281 CHEMBL1907587 Neuronal Acetylcholine Receptor; Alpha3/beta2 18
Z104283 Z104283 CHEMBL1907589 Neuronal Acetylcholine Receptor; Alpha4/beta2 18
ACHB4_HUMAN P30926 CHEMBL3002 Neuronal Acetylcholine Receptor Protein Beta-4 Subunit, Human 17
ACHA2_HUMAN Q15822 CHEMBL1794 Neuronal Acetylcholine Receptor Protein Alpha-2 Subunit, Human 14
Z104284 Z104284 CHEMBL1907590 Neuronal Acetylcholine Receptor; Alpha2/beta4 14
ACHA7_HUMAN P36544 CHEMBL2492 Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit, Human 12
ACHA_TORCA P02710 CHEMBL3097 Acetylcholine Receptor Protein Alpha Chain, Torca 9
ACHB_TORCA P02712 CHEMBL3803 Acetylcholine Receptor Protein Beta Chain, Torca 8
ACHG_TORCA P02714 CHEMBL4019 Acetylcholine Receptor Protein Gamma Chain, Torca 8
ACHA4_MOUSE O70174 CHEMBL4457 Neuronal Acetylcholine Receptor Protein Alpha-4 Subunit, Mouse 5
ACHB3_HUMAN Q05901 CHEMBL2586 Neuronal Acetylcholine Receptor Protein Beta-3 Subunit, Human 5
Q8BGP7_MOUSE Q8BGP7 CHEMBL2235 Neuronal Acetylcholine Receptor Protein Beta-2 Subunit, Mouse 5
ACHD_HUMAN Q07001 CHEMBL3011 Acetylcholine Receptor Protein Delta Chain, Human 4
VMAT2_RAT Q01827 CHEMBL4828 Synaptic Vesicular Amine Transporter, Rat 4
Z104288 Z104288 CHEMBL1907594 Neuronal Acetylcholine Receptor; Alpha3/beta4 4
ACHP_LYMST P58154 CHEMBL6084 Acetylcholine-binding Protein, Lymst 3
ACM1_HUMAN P11229 CHEMBL216 Muscarinic Acetylcholine Receptor M1, Human 3
SC6A3_RAT P23977 CHEMBL338 Dopamine Transporter, Rat 3
Z104285 Z104285 CHEMBL1907591 Neuronal Acetylcholine Receptor; Alpha4/beta4 3
ACH10_HUMAN Q9GZZ6 CHEMBL2551 Neuronal Acetylcholine Receptor Protein Alpha-10 Subunit, Human 2
ACHA5_HUMAN P30532 CHEMBL2454 Neuronal Acetylcholine Receptor Protein Alpha-5 Subunit, Human 2
ACHA6_HUMAN Q15825 CHEMBL2356 Neuronal Acetylcholine Receptor Protein Alpha-6 Subunit, Human 2
ACHA_HUMAN P02708 CHEMBL4808 Acetylcholine Receptor Protein Alpha Chain, Human 2
ACHB_HUMAN P11230 CHEMBL3355 Acetylcholine Receptor Protein Beta Chain, Human 2
ACHE_HUMAN Q04844 CHEMBL2484 Acetylcholine Receptor Protein Epsilon Chain, Human 2
ACHG_HUMAN P07510 CHEMBL2613 Acetylcholine Receptor Protein Gamma Chain, Human 2
ACM3_HUMAN P20309 CHEMBL245 Muscarinic Acetylcholine Receptor M3, Human 2
ACM5_HUMAN P08912 CHEMBL2035 Muscarinic Acetylcholine Receptor M5, Human 2
SC6A4_RAT P31652 CHEMBL313 Serotonin Transporter, Rat 2
VMAT2_HUMAN Q05940 CHEMBL1893 Synaptic Vesicular Amine Transporter, Human 2
Z104282 Z104282 CHEMBL1907588 Acetylcholine Receptor; Alpha1/beta1/delta/gamma 2
ACES_MOUSE P21836 CHEMBL3198 Acetylcholinesterase, Mouse 1
ACHA4_CHICK P09482 CHEMBL5569 Neuronal Acetylcholine Receptor Subunit Alpha-4, Chick 1
ACHA7_MOUSE P49582 CHEMBL3365 Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit, Mouse 1
ACM1_MOUSE P12657 CHEMBL3733 Muscarinic Acetylcholine Receptor M1, Mouse 1
ACM1_RAT P08482 CHEMBL276 Muscarinic Acetylcholine Receptor M1, Rat 1
ACM2_HUMAN P08172 CHEMBL211 Muscarinic Acetylcholine Receptor M2, Human 1
ACM2_MOUSE Q9ERZ4 CHEMBL3197 Muscarinic Acetylcholine Receptor M2, Mouse 1
ACM2_RAT P10980 CHEMBL309 Muscarinic Acetylcholine Receptor M2, Rat 1
ACM3_RAT P08483 CHEMBL320 Muscarinic Acetylcholine Receptor M3, Rat 1
ACM4_HUMAN P08173 CHEMBL1821 Muscarinic Acetylcholine Receptor M4, Human 1
ACM4_RAT P08485 CHEMBL317 Muscarinic Acetylcholine Receptor M4, Rat 1
AKT1_HUMAN P31749 CHEMBL4282 Serine/threonine-protein Kinase AKT, Human 1
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 1
Z50594 Z50594 CHEMBL375 Mus Musculus 1

Most Common Rings