ZINC 12

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Quick Search ZINC ID or SMILES

Names
Compounds (142)
Reactome (1)
Related By:
Pathway (10)
Organism (2)
Gene (7)
Org. Clust. (5)
ChEMBL (72)
Rings (18)

Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit, Human (142 Compounds)

Swissprot:: ACHA7_HUMAN
Stitch:: ACHA7_HUMAN
UniProt:: P36544
ChEMBL:: CHEMBL2492
Reactome:: REACT_22303
PDB:: CHRNA7

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	142	31	15	10
Binding ≤ 1μM	91	17	9	8
Functional ≤ 10μM	120	21	4	2

Reactome ID	Description	Species
REACT_22303	Highly calcium permeable postsynaptic nicotinic acetylcholine receptors	Homo sapiens

Uniprot	Swissprot	Chembl	Description	Number Shared
ACHA2_HUMAN	Q15822	CHEMBL1794	Neuronal Acetylcholine Receptor Protein Alpha-2 Subunit, Human	8
ACHA3_HUMAN	P32297	CHEMBL3068	Neuronal Acetylcholine Receptor Protein Alpha-3 Subunit, Human	31
ACHA4_HUMAN	P43681	CHEMBL1882	Neuronal Acetylcholine Receptor Protein Alpha-4 Subunit, Human	32
ACHA5_HUMAN	P30532	CHEMBL2454	Neuronal Acetylcholine Receptor Protein Alpha-5 Subunit, Human	5
ACHA6_HUMAN	Q15825	CHEMBL2356	Neuronal Acetylcholine Receptor Protein Alpha-6 Subunit, Human	5
ACHA9_HUMAN	Q9UGM1	CHEMBL2184	Neuronal Acetylcholine Receptor Protein Alpha-9 Subunit, Human	7
ACHA_HUMAN	P02708	CHEMBL4808	Acetylcholine Receptor Protein Alpha Chain, Human	6
ACHB2_HUMAN	P17787	CHEMBL1883	Neuronal Acetylcholine Receptor Protein Beta-2 Subunit, Human	28
ACHB3_HUMAN	Q05901	CHEMBL2586	Neuronal Acetylcholine Receptor Protein Beta-3 Subunit, Human	24
ACHB4_HUMAN	P30926	CHEMBL3002	Neuronal Acetylcholine Receptor Protein Beta-4 Subunit, Human	27

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
ACHA7_MOUSE	P49582	CHEMBL3365	Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit, Mouse	18	5	2	1
ACHA7_RAT	Q05941	CHEMBL4980	Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit, Rat	828	86	20	12

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
ACHA2_HUMAN	Q15822	CHEMBL1794	Neuronal Acetylcholine Receptor Protein Alpha-2 Subunit, Human	24	6	4	4
ACHA3_HUMAN	P32297	CHEMBL3068	Neuronal Acetylcholine Receptor Protein Alpha-3 Subunit, Human	84	15	7	7
ACHA4_HUMAN	P43681	CHEMBL1882	Neuronal Acetylcholine Receptor Protein Alpha-4 Subunit, Human	140	21	4	4
ACHA5_HUMAN	P30532	CHEMBL2454	Neuronal Acetylcholine Receptor Protein Alpha-5 Subunit, Human	5	3	1	0
ACHA6_HUMAN	Q15825	CHEMBL2356	Neuronal Acetylcholine Receptor Protein Alpha-6 Subunit, Human	5	3	1	0
ACHA9_HUMAN	Q9UGM1	CHEMBL2184	Neuronal Acetylcholine Receptor Protein Alpha-9 Subunit, Human	1	1	0	0
ACHA_HUMAN	P02708	CHEMBL4808	Acetylcholine Receptor Protein Alpha Chain, Human	8	3	1	0

Clustered By Gene (0)

Clustered By Organism (5)

Code	Description	Substances	Purchasable	Natural	In Man
ACHA7-1-E	Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit (cluster #1 Of 6), Eukaryotic	453	57	14	8
ACHA7-2-E	Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit (cluster #2 Of 6), Eukaryotic	298	28	2	6
ACHA7-3-E	Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit (cluster #3 Of 6), Eukaryotic	1	1	1	1
ACHA7-4-E	Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit (cluster #4 Of 6), Eukaryotic	1	1	1	0
ACHA7-5-E	Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit (cluster #5 Of 6), Eukaryotic	126	18	5	1
ACHA7-6-E	Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit (cluster #6 Of 6), Eukaryotic	104	10	10	3

Uniprot	Swissprot	Chembl	Description	Number Shared
Z104283	Z104283	CHEMBL1907589	Neuronal Acetylcholine Receptor; Alpha4/beta2	54
5HT3A_HUMAN	P46098	CHEMBL1899	Serotonin 3a (5-HT3a) Receptor, Human	51
5HT3B_HUMAN	O95264	CHEMBL3895	Serotonin 3b (5-HT3b) Receptor, Human	38
5HT3C_HUMAN	Q8WXA8	CHEMBL4795	Serotonin 3c (5-HT3c) Receptor, Human	38
5HT3D_HUMAN	Q70Z44	CHEMBL4673	Serotonin 3d (5-HT3d) Receptor, Human	38
5HT3E_HUMAN	A5X5Y0	CHEMBL3812	Serotonin 3e (5-HT3e) Receptor, Human	38
ACHA4_HUMAN	P43681	CHEMBL1882	Neuronal Acetylcholine Receptor Protein Alpha-4 Subunit, Human	31
ACHA3_HUMAN	P32297	CHEMBL3068	Neuronal Acetylcholine Receptor Protein Alpha-3 Subunit, Human	28
ACHA7_RAT	Q05941	CHEMBL4980	Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit, Rat	27
ACHB2_HUMAN	P17787	CHEMBL1883	Neuronal Acetylcholine Receptor Protein Beta-2 Subunit, Human	27
ACHB4_HUMAN	P30926	CHEMBL3002	Neuronal Acetylcholine Receptor Protein Beta-4 Subunit, Human	26
ACHB3_HUMAN	Q05901	CHEMBL2586	Neuronal Acetylcholine Receptor Protein Beta-3 Subunit, Human	24
Z104290	Z104290	CHEMBL1907596	Neuronal Acetylcholine Receptor; Alpha4/beta2	24
Z104288	Z104288	CHEMBL1907594	Neuronal Acetylcholine Receptor; Alpha3/beta4	22
ACHP_LYMST	P58154	CHEMBL6084	Acetylcholine-binding Protein, Lymst	21
ACHD_TORCA	P02718	CHEMBL3916	Acetylcholine Receptor Protein Delta Chain, Torca	20
ACHA4_RAT	P09483	CHEMBL307	Neuronal Acetylcholine Receptor Protein Alpha-4 Subunit, Rat	15
ACHA_TORCA	P02710	CHEMBL3097	Acetylcholine Receptor Protein Alpha Chain, Torca	15
ACHA3_RAT	P04757	CHEMBL3818	Neuronal Acetylcholine Receptor Protein Alpha-3 Subunit, Rat	13
ACHB_TORCA	P02712	CHEMBL3803	Acetylcholine Receptor Protein Beta Chain, Torca	13
ACHG_TORCA	P02714	CHEMBL4019	Acetylcholine Receptor Protein Gamma Chain, Torca	13
ACHB2_RAT	P12390	CHEMBL3001	Neuronal Acetylcholine Receptor Protein Beta-2 Subunit, Rat	12
ACH10_HUMAN	Q9GZZ6	CHEMBL2551	Neuronal Acetylcholine Receptor Protein Alpha-10 Subunit, Human	11
ACH10_RAT	Q9JLB5	CHEMBL3461	Neuronal Acetylcholine Receptor Protein Alpha-10 Subunit, Rat	10
ACHA2_RAT	P12389	CHEMBL2584	Neuronal Acetylcholine Receptor Protein Alpha-2 Subunit, Rat	10
ACHA9_RAT	P43144	CHEMBL2585	Neuronal Acetylcholine Receptor Protein Alpha-9 Subunit, Rat	10
ACHB4_RAT	P12392	CHEMBL2658	Neuronal Acetylcholine Receptor Protein Beta-4 Subunit, Rat	10
ACHD_HUMAN	Q07001	CHEMBL3011	Acetylcholine Receptor Protein Delta Chain, Human	10
ACHA4_MOUSE	O70174	CHEMBL4457	Neuronal Acetylcholine Receptor Protein Alpha-4 Subunit, Mouse	9
Q8BGP7_MOUSE	Q8BGP7	CHEMBL2235	Neuronal Acetylcholine Receptor Protein Beta-2 Subunit, Mouse	9
ACHA5_RAT	P20420	CHEMBL4960	Neuronal Acetylcholine Receptor Protein Alpha-5 Subunit, Rat	8
ACHA6_RAT	P43143	CHEMBL4747	Neuronal Acetylcholine Receptor Protein Alpha-6 Subunit, Rat	8
ACHA_RAT	P25108	CHEMBL3599	Acetylcholine Receptor Protein Alpha Chain, Rat	8
ACHB3_RAT	P12391	CHEMBL4568	Neuronal Acetylcholine Receptor Protein Beta-3 Subunit, Rat	8
ACHB_RAT	P25109	CHEMBL2666	Acetylcholine Receptor Protein Beta Chain, Rat	8
Z104287	Z104287	CHEMBL1907593	Neuronal Acetylcholine Receptor; Alpha3/beta4	8
ACHA2_HUMAN	Q15822	CHEMBL1794	Neuronal Acetylcholine Receptor Protein Alpha-2 Subunit, Human	7
ACHA9_HUMAN	Q9UGM1	CHEMBL2184	Neuronal Acetylcholine Receptor Protein Alpha-9 Subunit, Human	7
Z104282	Z104282	CHEMBL1907588	Acetylcholine Receptor; Alpha1/beta1/delta/gamma	7
ACHA_HUMAN	P02708	CHEMBL4808	Acetylcholine Receptor Protein Alpha Chain, Human	6
Z104281	Z104281	CHEMBL1907587	Neuronal Acetylcholine Receptor; Alpha3/beta2	6
ACHA5_HUMAN	P30532	CHEMBL2454	Neuronal Acetylcholine Receptor Protein Alpha-5 Subunit, Human	5
ACHA6_HUMAN	Q15825	CHEMBL2356	Neuronal Acetylcholine Receptor Protein Alpha-6 Subunit, Human	5
Z104286	Z104286	CHEMBL1907592	Neuronal Acetylcholine Receptor; Alpha2/beta2	5
Z104289	Z104289	CHEMBL1907595	Neuronal Acetylcholine Receptor; Alpha4/beta4	5
ACHB_HUMAN	P11230	CHEMBL3355	Acetylcholine Receptor Protein Beta Chain, Human	4
ACHE_HUMAN	Q04844	CHEMBL2484	Acetylcholine Receptor Protein Epsilon Chain, Human	4
ACHG_HUMAN	P07510	CHEMBL2613	Acetylcholine Receptor Protein Gamma Chain, Human	4
Z104284	Z104284	CHEMBL1907590	Neuronal Acetylcholine Receptor; Alpha2/beta4	4
5HT3A_RAT	P35563	CHEMBL2411	Serotonin 3a (5-HT3a) Receptor, Rat	3
KCNH2_HUMAN	Q12809	CHEMBL240	HERG, Human	3
Z104285	Z104285	CHEMBL1907591	Neuronal Acetylcholine Receptor; Alpha4/beta4	3
ACM3_HUMAN	P20309	CHEMBL245	Muscarinic Acetylcholine Receptor M3, Human	2
ACM4_HUMAN	P08173	CHEMBL1821	Muscarinic Acetylcholine Receptor M4, Human	2
ACM5_HUMAN	P08912	CHEMBL2035	Muscarinic Acetylcholine Receptor M5, Human	2
GBRG2_HUMAN	P18507	CHEMBL1788	GABA Receptor Gamma-2 Subunit, Human	2
Z50597	Z50597	CHEMBL376	Rattus Norvegicus	2
5HT3A_MOUSE	P23979	CHEMBL4972	Serotonin 3a (5-HT3a) Receptor, Mouse	1
5HT3B_RAT	Q9JJ16	CHEMBL3458	Serotonin 3b (5-HT3b) Receptor, Rat	1
ACHA4_CHICK	P09482	CHEMBL5569	Neuronal Acetylcholine Receptor Subunit Alpha-4, Chick	1
ACHA7_MOUSE	P49582	CHEMBL3365	Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit, Mouse	1
ACM1_HUMAN	P11229	CHEMBL216	Muscarinic Acetylcholine Receptor M1, Human	1
ACM2_HUMAN	P08172	CHEMBL211	Muscarinic Acetylcholine Receptor M2, Human	1
GBRA1_HUMAN	P14867	CHEMBL1962	GABA Receptor Alpha-1 Subunit, Human	1
GBRA2_HUMAN	P47869	CHEMBL4956	GABA Receptor Alpha-2 Subunit, Human	1
GBRB2_HUMAN	P47870	CHEMBL1920	GABA Receptor Beta-2 Subunit, Human	1
GBRB3_HUMAN	P28472	CHEMBL1847	GABA Receptor Beta-3 Subunit, Human	1
Z102306	Z102306	CHEMBL613606	Aorta	1
Z50425	Z50425	CHEMBL364	Plasmodium Falciparum	1
Z50594	Z50594	CHEMBL375	Mus Musculus	1
Z80175	Z80175	CHEMBL614585	IMR-32 (Neuroblastoma Cells)	1
Z81074	Z81074	CHEMBL614687	K177cell Line	1