ZINC 12

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Quick Search ZINC ID or SMILES

Names
Compounds (1,067)
Reactome (2)
Related By:
Pathway (20)
Organism (3)
Gene (2)
Org. Clust. (6)
ChEMBL (98)
Rings (38)

GABA Receptor Gamma-2 Subunit, Human (1,067 Compounds)

Swissprot:: GBRG2_HUMAN
Stitch:: GBRG2_HUMAN
UniProt:: P18507
ChEMBL:: CHEMBL1788
Reactome:: REACT_24987; REACT_25387
PDB:: GABRG2

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	1,067	54	23	21
Binding ≤ 1μM	1,005	44	19	17
Functional ≤ 10μM	84	9	5	7

Reactome ID	Description	Species
REACT_24987	GABA A receptor activation	Homo sapiens
REACT_25387	Ligand-gated ion channel transport	Homo sapiens

Uniprot	Swissprot	Chembl	Description	Number Shared
GBRA1_HUMAN	P14867	CHEMBL1962	GABA Receptor Alpha-1 Subunit, Human	907
GBRA2_HUMAN	P47869	CHEMBL4956	GABA Receptor Alpha-2 Subunit, Human	726
GBRA3_HUMAN	P34903	CHEMBL3026	GABA Receptor Alpha-3 Subunit, Human	871
GBRA4_HUMAN	P48169	CHEMBL2472	GABA Receptor Alpha-4 Subunit, Human	273
GBRA5_HUMAN	P31644	CHEMBL5112	GABA Receptor Alpha-5 Subunit, Human	848
GBRA6_HUMAN	Q16445	CHEMBL2579	GABA Receptor Alpha-6 Subunit, Human	331
GBRB1_HUMAN	P18505	CHEMBL4558	GABA Receptor Beta-1 Subunit, Human	250
GBRB2_HUMAN	P47870	CHEMBL1920	GABA Receptor Beta-2 Subunit, Human	381
GBRB3_HUMAN	P28472	CHEMBL1847	GABA Receptor Beta-3 Subunit, Human	1040
GBRG3_HUMAN	Q99928	CHEMBL2739	GABA Receptor Gamma-3 Subunit, Human	241
GBRT_HUMAN	Q9UN88	CHEMBL2843	GABA Receptor Theta Subunit, Human	166

Ligand-gated ion channel transport

Uniprot	Swissprot	Chembl	Description	Number Shared
GBRA1_HUMAN	P14867	CHEMBL1962	GABA Receptor Alpha-1 Subunit, Human	907
GBRA2_HUMAN	P47869	CHEMBL4956	GABA Receptor Alpha-2 Subunit, Human	726
GBRA3_HUMAN	P34903	CHEMBL3026	GABA Receptor Alpha-3 Subunit, Human	871
GBRA4_HUMAN	P48169	CHEMBL2472	GABA Receptor Alpha-4 Subunit, Human	273
GBRA5_HUMAN	P31644	CHEMBL5112	GABA Receptor Alpha-5 Subunit, Human	848
GBRA6_HUMAN	Q16445	CHEMBL2579	GABA Receptor Alpha-6 Subunit, Human	331
GBRB1_HUMAN	P18505	CHEMBL4558	GABA Receptor Beta-1 Subunit, Human	250
GBRB2_HUMAN	P47870	CHEMBL1920	GABA Receptor Beta-2 Subunit, Human	381
GBRB3_HUMAN	P28472	CHEMBL1847	GABA Receptor Beta-3 Subunit, Human	1040
GBRG3_HUMAN	Q99928	CHEMBL2739	GABA Receptor Gamma-3 Subunit, Human	241
GBRR1_HUMAN	P24046	CHEMBL3561	GABA Receptor Rho-1 Subunit, Human	3
GBRR2_HUMAN	P28476	CHEMBL2375	GABA Receptor Rho-2 Subunit, Human	3
GBRR3_HUMAN	A8MPY1	CHEMBL2394	GABA Receptor Rho-3 Subunit, Human	2
GBRT_HUMAN	Q9UN88	CHEMBL2843	GABA Receptor Theta Subunit, Human	166

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
GBRG2_BOVIN	P22300	CHEMBL5138	GABA Receptor Gamma-2 Subunit, Bovin	283	42	17	5
GBRG2_MOUSE	P22723	CHEMBL2941	GABA Receptor Gamma-2 Subunit, Mouse	37	3	2	2
GBRG2_RAT	P18508	CHEMBL297	GABA Receptor Gamma-2 Subunit, Rat	169	14	8	4

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
GBRG1_HUMAN	Q8N1C3	CHEMBL4044	GABA Receptor Gamma-1 Subunit, Human	240	19	11	9
GBRG3_HUMAN	Q99928	CHEMBL2739	GABA Receptor Gamma-3 Subunit, Human	240	19	11	9

Clustered By Gene (0)

Clustered By Organism (6)

Code	Description	Substances	Purchasable	Natural	In Man
GBRG2-1-E	GABA Receptor Gamma-2 Subunit (cluster #1 Of 7), Eukaryotic	1,318	56	27	20
GBRG2-2-E	GABA Receptor Gamma-2 Subunit (cluster #2 Of 7), Eukaryotic	160	33	9	0
GBRG2-3-E	GABA Receptor Gamma-2 Subunit (cluster #3 Of 7), Eukaryotic	3	1	1	1
GBRG2-4-E	GABA Receptor Gamma-2 Subunit (cluster #4 Of 7), Eukaryotic	5	3	1	1
GBRG2-5-E	GABA Receptor Gamma-2 Subunit (cluster #5 Of 7), Eukaryotic	22	0	0	0
GBRG2-6-E	GABA Receptor Gamma-2 Subunit (cluster #6 Of 7), Eukaryotic	4	4	1	1
GBRG2-7-E	GABA Receptor Gamma-2 Subunit (cluster #7 Of 7), Eukaryotic	3	0	0	0

Uniprot	Swissprot	Chembl	Description	Number Shared
GBRB3_HUMAN	P28472	CHEMBL1847	GABA Receptor Beta-3 Subunit, Human	1040
GBRA1_HUMAN	P14867	CHEMBL1962	GABA Receptor Alpha-1 Subunit, Human	907
GBRA3_HUMAN	P34903	CHEMBL3026	GABA Receptor Alpha-3 Subunit, Human	871
GBRA5_HUMAN	P31644	CHEMBL5112	GABA Receptor Alpha-5 Subunit, Human	848
GBRA2_HUMAN	P47869	CHEMBL4956	GABA Receptor Alpha-2 Subunit, Human	726
GBRB2_HUMAN	P47870	CHEMBL1920	GABA Receptor Beta-2 Subunit, Human	381
GBRA6_HUMAN	Q16445	CHEMBL2579	GABA Receptor Alpha-6 Subunit, Human	331
GBRA4_HUMAN	P48169	CHEMBL2472	GABA Receptor Alpha-4 Subunit, Human	273
GBRB1_HUMAN	P18505	CHEMBL4558	GABA Receptor Beta-1 Subunit, Human	250
GBRD_HUMAN	O14764	CHEMBL3591	GABA Receptor Delta Subunit, Human	243
GBRE_HUMAN	P78334	CHEMBL4635	GABA Receptor Epsilon Subunit, Human	241
GBRG1_HUMAN	Q8N1C3	CHEMBL4044	GABA Receptor Gamma-1 Subunit, Human	241
GBRG3_HUMAN	Q99928	CHEMBL2739	GABA Receptor Gamma-3 Subunit, Human	241
GBRP_HUMAN	O00591	CHEMBL3506	GABA Receptor Pi Subunit, Human	241
GBRT_HUMAN	Q9UN88	CHEMBL2843	GABA Receptor Theta Subunit, Human	166
Z104301	Z104301	CHEMBL1907607	GABA-A Receptor; Anion Channel	104
GBRA2_RAT	P23576	CHEMBL341	GABA Receptor Alpha-2 Subunit, Rat	53
GBRG2_RAT	P18508	CHEMBL297	GABA Receptor Gamma-2 Subunit, Rat	24
GBRB2_RAT	P63138	CHEMBL295	GABA Receptor Beta-2 Subunit, Rat	15
GBRA1_RAT	P62813	CHEMBL343	GABA Receptor Alpha-1 Subunit, Rat	14
GBRA5_RAT	P19969	CHEMBL300	GABA Receptor Alpha-5 Subunit, Rat	12
AA3R_HUMAN	P33765	CHEMBL256	Adenosine A3 Receptor, Human	10
GBRA3_RAT	P20236	CHEMBL328	GABA Receptor Alpha-3 Subunit, Rat	9
GBRB3_RAT	P63079	CHEMBL316	GABA Receptor Beta-3 Subunit, Rat	9
GBRA6_RAT	P30191	CHEMBL293	GABA Receptor Alpha-6 Subunit, Rat	8
AA1R_HUMAN	P30542	CHEMBL226	Adenosine A1 Receptor, Human	7
GBRA1_BOVIN	P08219	CHEMBL3627	GABA Receptor Alpha-1 Subunit, Bovin	7
GBRA2_BOVIN	P10063	CHEMBL2321	GABA Receptor Alpha-2 Subunit, Bovin	7
GBRA3_BOVIN	P10064	CHEMBL3628	GABA Receptor Alpha-3 Subunit, Bovin	7
GBRA4_BOVIN	P20237	CHEMBL3140	GABA Receptor Alpha-4 Subunit, Bovin	7
GBRA4_RAT	P28471	CHEMBL292	GABA Receptor Alpha-4 Subunit, Rat	7
GBRB1_BOVIN	P08220	CHEMBL2848	GABA Receptor Beta-1 Subunit, Bovin	7
GBRG2_BOVIN	P22300	CHEMBL5138	GABA Receptor Gamma-2 Subunit, Bovin	7
Z50597	Z50597	CHEMBL376	Rattus Norvegicus	7
GBRG1_RAT	P23574	CHEMBL296	GABA Receptor Gamma-1 Subunit, Rat	6
GBRG3_RAT	P28473	CHEMBL336	GABA Receptor Gamma-3 Subunit, Rat	4
5HT1A_RAT	P19327	CHEMBL273	Serotonin 1a (5-HT1a) Receptor, Rat	3
GBRA1_MOUSE	P62812	CHEMBL3139	GABA Receptor Alpha-1 Subunit, Mouse	3
GBRB1_RAT	P15431	CHEMBL334	GABA Receptor Beta-1 Subunit, Rat	3
GBRD_RAT	P18506	CHEMBL337	GABA Receptor Delta Subunit, Rat	3
GBRE_RAT	Q9ES14	CHEMBL306	GABA Receptor Epsilon Subunit, Rat	3
GBRR1_RAT	P50572	CHEMBL3588	GABA Receptor Rho-1 Subunit, Rat	3
Q91ZM7_RAT	Q91ZM7	CHEMBL305	GABA Receptor Theta Subunit, Rat	3
TSPO_RAT	P16257	CHEMBL4552	Peripheral-type Benzodiazepine Receptor, Rat	3
Z50594	Z50594	CHEMBL375	Mus Musculus	3
5HT1A_HUMAN	P08908	CHEMBL214	Serotonin 1a (5-HT1a) Receptor, Human	2
5HT1D_HUMAN	P28221	CHEMBL1983	Serotonin 1d (5-HT1d) Receptor, Human	2
A2AMW3_MOUSE	A2AMW3	CHEMBL3121	GABA Receptor Epsilon Subunit, Mouse	2
ACHA7_HUMAN	P36544	CHEMBL2492	Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit, Human	2
GBRA2_MOUSE	P26048	CHEMBL2705	GABA Receptor Alpha-2 Subunit, Mouse	2
GBRA3_MOUSE	P26049	CHEMBL3387	GABA Receptor Alpha-3 Subunit, Mouse	2
GBRA4_MOUSE	Q9D6F4	CHEMBL4182	GABA Receptor Alpha-4 Subunit, Mouse	2
GBRA5_MOUSE	Q8BHJ7	CHEMBL2304	GABA Receptor Alpha-5 Subunit, Mouse	2
GBRA6_MOUSE	P16305	CHEMBL4710	GABA Receptor Alpha-6 Subunit, Mouse	2
GBRB1_MOUSE	P50571	CHEMBL2839	GABA Receptor Beta-1 Subunit, Mouse	2
GBRB3_MOUSE	P63080	CHEMBL4231	GABA Receptor Beta-3 Subunit, Mouse	2
GBRD_MOUSE	P22933	CHEMBL3907	GABA Receptor Delta Subunit, Mouse	2
GBRG1_MOUSE	Q9R0Y8	CHEMBL2891	GABA Receptor Gamma-1 Subunit, Mouse	2
GBRG2_MOUSE	P22723	CHEMBL2941	GABA Receptor Gamma-2 Subunit, Mouse	2
GBRG3_MOUSE	P27681	CHEMBL4236	GABA Receptor Gamma-3 Subunit, Mouse	2
GBRP_MOUSE	Q8QZW7	CHEMBL2746	GABA Receptor Pi Subunit, Mouse	2
GBRR1_HUMAN	P24046	CHEMBL3561	GABA Receptor Rho-1 Subunit, Human	2
GBRR2_HUMAN	P28476	CHEMBL2375	GABA Receptor Rho-2 Subunit, Human	2
GBRR3_HUMAN	A8MPY1	CHEMBL2394	GABA Receptor Rho-3 Subunit, Human	2
GBRT_MOUSE	Q9JLF1	CHEMBL3249	GABA Receptor Theta Subunit, Mouse	2
Z50573	Z50573	CHEMBL613478	Xenopus Laevis	2
Z50574	Z50574	CHEMBL612667	Xenopus Sp.	2
5HT1D_PIG	P79400	CHEMBL4105	Serotonin 1d (5-HT1d) Receptor, Pig	1
5HT1D_RAT	P28565	CHEMBL5450	Serotonin 1d (5-HT1d) Receptor, Rat	1
5HT2C_HUMAN	P28335	CHEMBL225	Serotonin 2c (5-HT2c) Receptor, Human	1
AA1R_RAT	P25099	CHEMBL318	Adenosine A1 Receptor, Rat	1
AA2AR_RAT	P30543	CHEMBL302	Adenosine A2a Receptor, Rat	1
AA2BR_RAT	P29276	CHEMBL2592	Adenosine A2b Receptor, Rat	1
ACHA7_RAT	Q05941	CHEMBL4980	Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit, Rat	1
BACE1_HUMAN	P56817	CHEMBL4822	Beta-secretase 1, Human	1
C11B1_HUMAN	P15538	CHEMBL1908	Cytochrome P450 11B1, Human	1
C11B2_HUMAN	P19099	CHEMBL2722	Cytochrome P450 11B2, Human	1
CCKAR_RAT	P30551	CHEMBL2871	Cholecystokinin A Receptor, Rat	1
CP19A_HUMAN	P11511	CHEMBL1978	Cytochrome P450 19A1, Human	1
DRD3_HUMAN	P35462	CHEMBL234	Dopamine D3 Receptor, Human	1
FABPL_RAT	P02692	CHEMBL5738	Fatty Acid-binding Protein, Liver, Rat	1
GABR1_HUMAN	Q9UBS5	CHEMBL2064	GABA-B Receptor 1, Human	1
GABR1_RAT	Q9Z0U4	CHEMBL2753	GABA-B Receptor 1, Rat	1
GABR2_HUMAN	O75899	CHEMBL5034	GABA-B Receptor 2, Human	1
GABR2_RAT	O88871	CHEMBL4686	GABA-B Receptor 2, Rat	1
GASR_RAT	P30553	CHEMBL3508	Cholecystokinin B Receptor, Rat	1
GBRP_RAT	O09028	CHEMBL294	GABA Receptor Pi Subunit, Rat	1
GBRR2_RAT	P47742	CHEMBL2953	GABA Receptor Rho-2 Subunit, Rat	1
OPRD_HUMAN	P41143	CHEMBL236	Delta Opioid Receptor, Human	1
OPRD_PIG	P79291	CHEMBL4103	Delta Opioid Receptor, Pig	1
PDE5A_BOVIN	Q28156	CHEMBL3478	Phosphodiesterase 5A, Bovin	1
S6A11_HUMAN	P48066	CHEMBL5208	GABA Transporter 3, Human	1
S6A11_RAT	P31647	CHEMBL3598	GABA Transporter 3, Rat	1
S6A12_RAT	P48056	CHEMBL5248	Betaine Transporter, Rat	1
S6A13_RAT	P31646	CHEMBL4889	GABA Transporter 2, Rat	1
SC6A1_HUMAN	P30531	CHEMBL1903	GABA Transporter 1, Human	1
SC6A1_RAT	P23978	CHEMBL4054	GABA Transporter 1, Rat	1
Z50425	Z50425	CHEMBL364	Plasmodium Falciparum	1