UCSF

GABA Receptor Beta-2 Subunit, Rat (169 Compounds)

Swissprot:
GBRB2_RAT
Stitch:
GBRB2_RAT
UniProt:
P63138
ChEMBL:
CHEMBL295
Reactome:
REACT_199021
REACT_199029
PDB:
Gabrb2

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 169 20 8 5
Binding ≤ 1μM 143 15 8 5

Reactome Network (2)

Reactome ID Description Species
REACT_199021 GABA A receptor activation Rattus norvegicus
REACT_199029 Ligand-gated ion channel transport Rattus norvegicus
Uniprot Swissprot Chembl Description Number Shared
GBRA1_RAT P62813 CHEMBL343 GABA Receptor Alpha-1 Subunit, Rat 138
GBRA4_RAT P28471 CHEMBL292 GABA Receptor Alpha-4 Subunit, Rat 88
GBRA5_RAT P19969 CHEMBL300 GABA Receptor Alpha-5 Subunit, Rat 120
GBRG2_RAT P18508 CHEMBL297 GABA Receptor Gamma-2 Subunit, Rat 147
GBRG3_RAT P28473 CHEMBL336 GABA Receptor Gamma-3 Subunit, Rat 78

Ligand-gated ion channel transport

Uniprot Swissprot Chembl Description Number Shared
GBRA1_RAT P62813 CHEMBL343 GABA Receptor Alpha-1 Subunit, Rat 138
GBRA4_RAT P28471 CHEMBL292 GABA Receptor Alpha-4 Subunit, Rat 88
GBRA5_RAT P19969 CHEMBL300 GABA Receptor Alpha-5 Subunit, Rat 120
GBRG2_RAT P18508 CHEMBL297 GABA Receptor Gamma-2 Subunit, Rat 147
GBRG3_RAT P28473 CHEMBL336 GABA Receptor Gamma-3 Subunit, Rat 78
GBRR2_RAT P47742 CHEMBL2953 GABA Receptor Rho-2 Subunit, Rat 8
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
GBRB2_HUMAN P47870 CHEMBL1920 GABA Receptor Beta-2 Subunit, Human 333 30 17 16
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
GBRB1_RAT P15431 CHEMBL334 GABA Receptor Beta-1 Subunit, Rat 124 15 10 6
GBRB3_RAT P63079 CHEMBL316 GABA Receptor Beta-3 Subunit, Rat 166 20 12 7

Clustered By Gene (0)

Clustered By Organism (6)

Code Description Substances Purchasable Natural In Man
GBRB2-1-E GABA Receptor Beta-2 Subunit (cluster #1 Of 7), Eukaryotic 349 19 14 13
GBRB2-2-E GABA Receptor Beta-2 Subunit (cluster #2 Of 7), Eukaryotic 20 5 1 1
GBRB2-3-E GABA Receptor Beta-2 Subunit (cluster #3 Of 7), Eukaryotic 3 3 1 1
GBRB2-4-E GABA Receptor Beta-2 Subunit (cluster #4 Of 7), Eukaryotic 21 2 1 1
GBRB2-5-E GABA Receptor Beta-2 Subunit (cluster #5 Of 7), Eukaryotic 4 4 1 1
GBRB2-6-E GABA Receptor Beta-2 Subunit (cluster #6 Of 7), Eukaryotic 90 13 3 0
GBRB2-7-E GABA Receptor Beta-2 Subunit (cluster #7 Of 7), Eukaryotic 4 0 0 0
Uniprot Swissprot Chembl Description Number Shared
GBRG2_RAT P18508 CHEMBL297 GABA Receptor Gamma-2 Subunit, Rat 147
GBRA1_RAT P62813 CHEMBL343 GABA Receptor Alpha-1 Subunit, Rat 138
GBRB3_RAT P63079 CHEMBL316 GABA Receptor Beta-3 Subunit, Rat 135
GBRA5_RAT P19969 CHEMBL300 GABA Receptor Alpha-5 Subunit, Rat 120
GBRA2_RAT P23576 CHEMBL341 GABA Receptor Alpha-2 Subunit, Rat 113
GBRB1_RAT P15431 CHEMBL334 GABA Receptor Beta-1 Subunit, Rat 104
GBRA3_RAT P20236 CHEMBL328 GABA Receptor Alpha-3 Subunit, Rat 97
GBRA4_RAT P28471 CHEMBL292 GABA Receptor Alpha-4 Subunit, Rat 88
GBRA6_RAT P30191 CHEMBL293 GABA Receptor Alpha-6 Subunit, Rat 85
GBRG1_RAT P23574 CHEMBL296 GABA Receptor Gamma-1 Subunit, Rat 84
Q91ZM7_RAT Q91ZM7 CHEMBL305 GABA Receptor Theta Subunit, Rat 84
GBRD_RAT P18506 CHEMBL337 GABA Receptor Delta Subunit, Rat 81
GBRE_RAT Q9ES14 CHEMBL306 GABA Receptor Epsilon Subunit, Rat 81
GBRG3_RAT P28473 CHEMBL336 GABA Receptor Gamma-3 Subunit, Rat 78
GBRR1_RAT P50572 CHEMBL3588 GABA Receptor Rho-1 Subunit, Rat 75
GBRA1_BOVIN P08219 CHEMBL3627 GABA Receptor Alpha-1 Subunit, Bovin 30
GBRA2_BOVIN P10063 CHEMBL2321 GABA Receptor Alpha-2 Subunit, Bovin 30
GBRA3_BOVIN P10064 CHEMBL3628 GABA Receptor Alpha-3 Subunit, Bovin 30
GBRA4_BOVIN P20237 CHEMBL3140 GABA Receptor Alpha-4 Subunit, Bovin 30
GBRB1_BOVIN P08220 CHEMBL2848 GABA Receptor Beta-1 Subunit, Bovin 30
GBRG2_BOVIN P22300 CHEMBL5138 GABA Receptor Gamma-2 Subunit, Bovin 30
GBRP_RAT O09028 CHEMBL294 GABA Receptor Pi Subunit, Rat 17
Z104301 Z104301 CHEMBL1907607 GABA-A Receptor; Anion Channel 17
GBRA1_HUMAN P14867 CHEMBL1962 GABA Receptor Alpha-1 Subunit, Human 16
GBRG2_HUMAN P18507 CHEMBL1788 GABA Receptor Gamma-2 Subunit, Human 15
GBRA3_HUMAN P34903 CHEMBL3026 GABA Receptor Alpha-3 Subunit, Human 14
GBRA2_HUMAN P47869 CHEMBL4956 GABA Receptor Alpha-2 Subunit, Human 13
GBRB2_HUMAN P47870 CHEMBL1920 GABA Receptor Beta-2 Subunit, Human 13
GBRA5_HUMAN P31644 CHEMBL5112 GABA Receptor Alpha-5 Subunit, Human 12
GBRB3_HUMAN P28472 CHEMBL1847 GABA Receptor Beta-3 Subunit, Human 12
GBRA1_MOUSE P62812 CHEMBL3139 GABA Receptor Alpha-1 Subunit, Mouse 10
GBRA6_HUMAN Q16445 CHEMBL2579 GABA Receptor Alpha-6 Subunit, Human 10
GBRA4_HUMAN P48169 CHEMBL2472 GABA Receptor Alpha-4 Subunit, Human 8
GBRB1_HUMAN P18505 CHEMBL4558 GABA Receptor Beta-1 Subunit, Human 8
GBRD_HUMAN O14764 CHEMBL3591 GABA Receptor Delta Subunit, Human 8
GBRE_HUMAN P78334 CHEMBL4635 GABA Receptor Epsilon Subunit, Human 8
GBRG1_HUMAN Q8N1C3 CHEMBL4044 GABA Receptor Gamma-1 Subunit, Human 8
GBRG3_HUMAN Q99928 CHEMBL2739 GABA Receptor Gamma-3 Subunit, Human 8
GBRP_HUMAN O00591 CHEMBL3506 GABA Receptor Pi Subunit, Human 8
GBRR2_RAT P47742 CHEMBL2953 GABA Receptor Rho-2 Subunit, Rat 8
GBRT_HUMAN Q9UN88 CHEMBL2843 GABA Receptor Theta Subunit, Human 8
GABR1_RAT Q9Z0U4 CHEMBL2753 GABA-B Receptor 1, Rat 6
GABR2_RAT O88871 CHEMBL4686 GABA-B Receptor 2, Rat 6
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 5
AA1R_HUMAN P30542 CHEMBL226 Adenosine A1 Receptor, Human 3
A2AMW3_MOUSE A2AMW3 CHEMBL3121 GABA Receptor Epsilon Subunit, Mouse 2
GBRA2_MOUSE P26048 CHEMBL2705 GABA Receptor Alpha-2 Subunit, Mouse 2
GBRA3_MOUSE P26049 CHEMBL3387 GABA Receptor Alpha-3 Subunit, Mouse 2
GBRA4_MOUSE Q9D6F4 CHEMBL4182 GABA Receptor Alpha-4 Subunit, Mouse 2
GBRA5_MOUSE Q8BHJ7 CHEMBL2304 GABA Receptor Alpha-5 Subunit, Mouse 2
GBRA6_MOUSE P16305 CHEMBL4710 GABA Receptor Alpha-6 Subunit, Mouse 2
GBRB1_MOUSE P50571 CHEMBL2839 GABA Receptor Beta-1 Subunit, Mouse 2
GBRB3_MOUSE P63080 CHEMBL4231 GABA Receptor Beta-3 Subunit, Mouse 2
GBRD_MOUSE P22933 CHEMBL3907 GABA Receptor Delta Subunit, Mouse 2
GBRG1_MOUSE Q9R0Y8 CHEMBL2891 GABA Receptor Gamma-1 Subunit, Mouse 2
GBRG2_MOUSE P22723 CHEMBL2941 GABA Receptor Gamma-2 Subunit, Mouse 2
GBRG3_MOUSE P27681 CHEMBL4236 GABA Receptor Gamma-3 Subunit, Mouse 2
GBRP_MOUSE Q8QZW7 CHEMBL2746 GABA Receptor Pi Subunit, Mouse 2
GBRT_MOUSE Q9JLF1 CHEMBL3249 GABA Receptor Theta Subunit, Mouse 2
TSPO_RAT P16257 CHEMBL4552 Peripheral-type Benzodiazepine Receptor, Rat 2
FABPL_RAT P02692 CHEMBL5738 Fatty Acid-binding Protein, Liver, Rat 1
GABR1_HUMAN Q9UBS5 CHEMBL2064 GABA-B Receptor 1, Human 1
GABR2_HUMAN O75899 CHEMBL5034 GABA-B Receptor 2, Human 1
GBRR1_HUMAN P24046 CHEMBL3561 GABA Receptor Rho-1 Subunit, Human 1
GBRR2_HUMAN P28476 CHEMBL2375 GABA Receptor Rho-2 Subunit, Human 1
GBRR3_HUMAN A8MPY1 CHEMBL2394 GABA Receptor Rho-3 Subunit, Human 1
PDE5A_BOVIN Q28156 CHEMBL3478 Phosphodiesterase 5A, Bovin 1

Most Common Rings