UCSF

GABA Receptor Alpha-5 Subunit, Rat (189 Compounds)

Swissprot:
GBRA5_RAT
Stitch:
GBRA5_RAT
UniProt:
P19969
ChEMBL:
CHEMBL300
Reactome:
REACT_199021
REACT_199029
PDB:
Gabra5

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 189 15 11 7
Binding ≤ 1μM 162 12 10 6

Reactome Network (2)

Reactome ID Description Species
REACT_199021 GABA A receptor activation Rattus norvegicus
REACT_199029 Ligand-gated ion channel transport Rattus norvegicus
Uniprot Swissprot Chembl Description Number Shared
GBRA1_RAT P62813 CHEMBL343 GABA Receptor Alpha-1 Subunit, Rat 162
GBRA4_RAT P28471 CHEMBL292 GABA Receptor Alpha-4 Subunit, Rat 147
GBRB2_RAT P63138 CHEMBL295 GABA Receptor Beta-2 Subunit, Rat 120
GBRG2_RAT P18508 CHEMBL297 GABA Receptor Gamma-2 Subunit, Rat 122
GBRG3_RAT P28473 CHEMBL336 GABA Receptor Gamma-3 Subunit, Rat 99

Ligand-gated ion channel transport

Uniprot Swissprot Chembl Description Number Shared
GBRA1_RAT P62813 CHEMBL343 GABA Receptor Alpha-1 Subunit, Rat 162
GBRA4_RAT P28471 CHEMBL292 GABA Receptor Alpha-4 Subunit, Rat 147
GBRB2_RAT P63138 CHEMBL295 GABA Receptor Beta-2 Subunit, Rat 120
GBRG2_RAT P18508 CHEMBL297 GABA Receptor Gamma-2 Subunit, Rat 122
GBRG3_RAT P28473 CHEMBL336 GABA Receptor Gamma-3 Subunit, Rat 99
GBRR2_RAT P47742 CHEMBL2953 GABA Receptor Rho-2 Subunit, Rat 8
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
GBRA5_HUMAN P31644 CHEMBL5112 GABA Receptor Alpha-5 Subunit, Human 957 69 31 18
GBRA5_MOUSE Q8BHJ7 CHEMBL2304 GABA Receptor Alpha-5 Subunit, Mouse 37 3 2 2
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
GBRA1_RAT P62813 CHEMBL343 GABA Receptor Alpha-1 Subunit, Rat 207 16 9 6
GBRA2_RAT P23576 CHEMBL341 GABA Receptor Alpha-2 Subunit, Rat 250 27 18 11
GBRA3_RAT P20236 CHEMBL328 GABA Receptor Alpha-3 Subunit, Rat 159 12 11 7
GBRA4_RAT P28471 CHEMBL292 GABA Receptor Alpha-4 Subunit, Rat 147 11 11 7
GBRA6_RAT P30191 CHEMBL293 GABA Receptor Alpha-6 Subunit, Rat 146 12 11 7

Clustered By Gene (0)

Clustered By Organism (7)

Code Description Substances Purchasable Natural In Man
GBRA5-1-E GABA Receptor Alpha-5 Subunit (cluster #1 Of 8), Eukaryotic 830 25 13 8
GBRA5-2-E GABA Receptor Alpha-5 Subunit (cluster #2 Of 8), Eukaryotic 24 4 4 3
GBRA5-3-E GABA Receptor Alpha-5 Subunit (cluster #3 Of 8), Eukaryotic 154 16 7 2
GBRA5-4-E GABA Receptor Alpha-5 Subunit (cluster #4 Of 8), Eukaryotic 3 0 0 0
GBRA5-5-E GABA Receptor Alpha-5 Subunit (cluster #5 Of 8), Eukaryotic 4 4 1 1
GBRA5-6-E GABA Receptor Alpha-5 Subunit (cluster #6 Of 8), Eukaryotic 134 30 16 10
GBRA5-7-E GABA Receptor Alpha-5 Subunit (cluster #7 Of 8), Eukaryotic 30 0 0 0
GBRA5-8-E GABA Receptor Alpha-5 Subunit (cluster #8 Of 8), Eukaryotic 4 4 1 1
Uniprot Swissprot Chembl Description Number Shared
GBRA2_RAT P23576 CHEMBL341 GABA Receptor Alpha-2 Subunit, Rat 177
GBRA1_RAT P62813 CHEMBL343 GABA Receptor Alpha-1 Subunit, Rat 162
GBRA3_RAT P20236 CHEMBL328 GABA Receptor Alpha-3 Subunit, Rat 157
GBRA4_RAT P28471 CHEMBL292 GABA Receptor Alpha-4 Subunit, Rat 147
GBRA6_RAT P30191 CHEMBL293 GABA Receptor Alpha-6 Subunit, Rat 141
GBRB3_RAT P63079 CHEMBL316 GABA Receptor Beta-3 Subunit, Rat 134
GBRG2_RAT P18508 CHEMBL297 GABA Receptor Gamma-2 Subunit, Rat 122
GBRB2_RAT P63138 CHEMBL295 GABA Receptor Beta-2 Subunit, Rat 120
GBRG1_RAT P23574 CHEMBL296 GABA Receptor Gamma-1 Subunit, Rat 106
GBRB1_RAT P15431 CHEMBL334 GABA Receptor Beta-1 Subunit, Rat 104
Q91ZM7_RAT Q91ZM7 CHEMBL305 GABA Receptor Theta Subunit, Rat 104
GBRD_RAT P18506 CHEMBL337 GABA Receptor Delta Subunit, Rat 101
GBRE_RAT Q9ES14 CHEMBL306 GABA Receptor Epsilon Subunit, Rat 101
GBRG3_RAT P28473 CHEMBL336 GABA Receptor Gamma-3 Subunit, Rat 99
GBRR1_RAT P50572 CHEMBL3588 GABA Receptor Rho-1 Subunit, Rat 75
GBRP_RAT O09028 CHEMBL294 GABA Receptor Pi Subunit, Rat 37
GBRA1_BOVIN P08219 CHEMBL3627 GABA Receptor Alpha-1 Subunit, Bovin 26
GBRA2_BOVIN P10063 CHEMBL2321 GABA Receptor Alpha-2 Subunit, Bovin 26
GBRA3_BOVIN P10064 CHEMBL3628 GABA Receptor Alpha-3 Subunit, Bovin 26
GBRA4_BOVIN P20237 CHEMBL3140 GABA Receptor Alpha-4 Subunit, Bovin 26
GBRB1_BOVIN P08220 CHEMBL2848 GABA Receptor Beta-1 Subunit, Bovin 26
GBRG2_BOVIN P22300 CHEMBL5138 GABA Receptor Gamma-2 Subunit, Bovin 26
Z104301 Z104301 CHEMBL1907607 GABA-A Receptor; Anion Channel 18
GBRA1_HUMAN P14867 CHEMBL1962 GABA Receptor Alpha-1 Subunit, Human 13
GBRA2_HUMAN P47869 CHEMBL4956 GABA Receptor Alpha-2 Subunit, Human 12
GBRA3_HUMAN P34903 CHEMBL3026 GABA Receptor Alpha-3 Subunit, Human 12
GBRA5_HUMAN P31644 CHEMBL5112 GABA Receptor Alpha-5 Subunit, Human 12
GBRG2_HUMAN P18507 CHEMBL1788 GABA Receptor Gamma-2 Subunit, Human 12
GBRB3_HUMAN P28472 CHEMBL1847 GABA Receptor Beta-3 Subunit, Human 11
GBRA6_HUMAN Q16445 CHEMBL2579 GABA Receptor Alpha-6 Subunit, Human 10
GBRB2_HUMAN P47870 CHEMBL1920 GABA Receptor Beta-2 Subunit, Human 10
GBRA1_MOUSE P62812 CHEMBL3139 GABA Receptor Alpha-1 Subunit, Mouse 9
GBRR2_RAT P47742 CHEMBL2953 GABA Receptor Rho-2 Subunit, Rat 8
GBRA4_HUMAN P48169 CHEMBL2472 GABA Receptor Alpha-4 Subunit, Human 7
GBRB1_HUMAN P18505 CHEMBL4558 GABA Receptor Beta-1 Subunit, Human 7
GBRD_HUMAN O14764 CHEMBL3591 GABA Receptor Delta Subunit, Human 7
GBRE_HUMAN P78334 CHEMBL4635 GABA Receptor Epsilon Subunit, Human 7
GBRG1_HUMAN Q8N1C3 CHEMBL4044 GABA Receptor Gamma-1 Subunit, Human 7
GBRG3_HUMAN Q99928 CHEMBL2739 GABA Receptor Gamma-3 Subunit, Human 7
GBRP_HUMAN O00591 CHEMBL3506 GABA Receptor Pi Subunit, Human 7
GBRT_HUMAN Q9UN88 CHEMBL2843 GABA Receptor Theta Subunit, Human 7
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 4
AA1R_HUMAN P30542 CHEMBL226 Adenosine A1 Receptor, Human 3
TSPO_RAT P16257 CHEMBL4552 Peripheral-type Benzodiazepine Receptor, Rat 2
A2AMW3_MOUSE A2AMW3 CHEMBL3121 GABA Receptor Epsilon Subunit, Mouse 1
DHB3_HUMAN P37058 CHEMBL4234 Estradiol 17-beta-dehydrogenase 3, Human 1
FABPL_RAT P02692 CHEMBL5738 Fatty Acid-binding Protein, Liver, Rat 1
GBRA2_MOUSE P26048 CHEMBL2705 GABA Receptor Alpha-2 Subunit, Mouse 1
GBRA3_MOUSE P26049 CHEMBL3387 GABA Receptor Alpha-3 Subunit, Mouse 1
GBRA4_MOUSE Q9D6F4 CHEMBL4182 GABA Receptor Alpha-4 Subunit, Mouse 1
GBRA5_MOUSE Q8BHJ7 CHEMBL2304 GABA Receptor Alpha-5 Subunit, Mouse 1
GBRA6_MOUSE P16305 CHEMBL4710 GABA Receptor Alpha-6 Subunit, Mouse 1
GBRB1_MOUSE P50571 CHEMBL2839 GABA Receptor Beta-1 Subunit, Mouse 1
GBRB3_MOUSE P63080 CHEMBL4231 GABA Receptor Beta-3 Subunit, Mouse 1
GBRD_MOUSE P22933 CHEMBL3907 GABA Receptor Delta Subunit, Mouse 1
GBRG1_MOUSE Q9R0Y8 CHEMBL2891 GABA Receptor Gamma-1 Subunit, Mouse 1
GBRG2_MOUSE P22723 CHEMBL2941 GABA Receptor Gamma-2 Subunit, Mouse 1
GBRG3_MOUSE P27681 CHEMBL4236 GABA Receptor Gamma-3 Subunit, Mouse 1
GBRP_MOUSE Q8QZW7 CHEMBL2746 GABA Receptor Pi Subunit, Mouse 1
GBRT_MOUSE Q9JLF1 CHEMBL3249 GABA Receptor Theta Subunit, Mouse 1
PDE5A_BOVIN Q28156 CHEMBL3478 Phosphodiesterase 5A, Bovin 1