UCSF

Estradiol 17-beta-dehydrogenase 3, Human (179 Compounds)

Swissprot:
DHB3_HUMAN
Stitch:
DHB3_HUMAN
UniProt:
P37058
ChEMBL:
CHEMBL4234
Reactome:
REACT_11059
REACT_380
PDB:
HSD17B3

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 179 23 12 3
Binding ≤ 1μM 158 19 10 3

Reactome Network (2)

Reactome ID Description Species
REACT_11059 Androgen biosynthesis Homo sapiens
REACT_380 Synthesis of very long-chain fatty acyl-CoAs Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
S5A1_HUMAN P18405 CHEMBL1787 Steroid 5-alpha-reductase 1, Human 1
S5A2_HUMAN P31213 CHEMBL1856 Steroid 5-alpha-reductase 2, Human 1
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
DHB3_RAT O54939 CHEMBL1075158 Testosterone 17-beta-dehydrogenase 3, Rat 9 5 1 1
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
DHB1_HUMAN P14061 CHEMBL3181 Estradiol 17-beta-dehydrogenase 1, Human 217 12 8 5
DHB2_HUMAN P37059 CHEMBL2789 Estradiol 17-beta-dehydrogenase 2, Human 183 4 4 3
DHB7_HUMAN P56937 CHEMBL5999 3-keto-steroid Reductase, Human 4 0 0 0

Clustered By Gene (0)

Clustered By Organism (3)

Code Description Substances Purchasable Natural In Man
DHB3-1-E Estradiol 17-beta-dehydrogenase 3 (cluster #1 Of 4), Eukaryotic 16 8 2 1
DHB3-2-E Estradiol 17-beta-dehydrogenase 3 (cluster #2 Of 4), Eukaryotic 37 17 9 1
DHB3-3-E Estradiol 17-beta-dehydrogenase 3 (cluster #3 Of 4), Eukaryotic 89 2 2 2
DHB3-4-E Estradiol 17-beta-dehydrogenase 3 (cluster #4 Of 4), Eukaryotic 44 0 0 0
Uniprot Swissprot Chembl Description Number Shared
DHB3_RAT O54939 CHEMBL1075158 Testosterone 17-beta-dehydrogenase 3, Rat 2
ALDH2_HUMAN P05091 CHEMBL1935 Aldehyde Dehydrogenase, Human 1
ALDR_HUMAN P15121 CHEMBL1900 Aldose Reductase, Human 1
AOFA_HUMAN P21397 CHEMBL1951 Monoamine Oxidase A, Human 1
AOFA_RAT P21396 CHEMBL3358 Monoamine Oxidase A, Rat 1
AOFB_HUMAN P27338 CHEMBL2039 Monoamine Oxidase B, Human 1
CP19A_HUMAN P11511 CHEMBL1978 Cytochrome P450 19A1, Human 1
GBRA2_RAT P23576 CHEMBL341 GABA Receptor Alpha-2 Subunit, Rat 1
GBRA3_RAT P20236 CHEMBL328 GABA Receptor Alpha-3 Subunit, Rat 1
GBRA4_RAT P28471 CHEMBL292 GABA Receptor Alpha-4 Subunit, Rat 1
GBRA5_RAT P19969 CHEMBL300 GABA Receptor Alpha-5 Subunit, Rat 1
GBRA6_RAT P30191 CHEMBL293 GABA Receptor Alpha-6 Subunit, Rat 1
GBRB1_RAT P15431 CHEMBL334 GABA Receptor Beta-1 Subunit, Rat 1
GBRB3_RAT P63079 CHEMBL316 GABA Receptor Beta-3 Subunit, Rat 1
GBRD_RAT P18506 CHEMBL337 GABA Receptor Delta Subunit, Rat 1
GBRE_RAT Q9ES14 CHEMBL306 GABA Receptor Epsilon Subunit, Rat 1
GBRG1_RAT P23574 CHEMBL296 GABA Receptor Gamma-1 Subunit, Rat 1
GBRG3_RAT P28473 CHEMBL336 GABA Receptor Gamma-3 Subunit, Rat 1
GBRP_RAT O09028 CHEMBL294 GABA Receptor Pi Subunit, Rat 1
Q91ZM7_RAT Q91ZM7 CHEMBL305 GABA Receptor Theta Subunit, Rat 1
S5A1_HUMAN P18405 CHEMBL1787 Steroid 5-alpha-reductase 1, Human 1
S5A2_HUMAN P31213 CHEMBL1856 Steroid 5-alpha-reductase 2, Human 1

Most Common Rings