UCSF

Phosphodiesterase 5A, Bovin (180 Compounds)

Swissprot:
PDE5A_BOVIN
Stitch:
PDE5A_BOVIN
UniProt:
Q28156
ChEMBL:
CHEMBL3478
Reactome:
REACT_205403
PDB:
1FL4 (DOCK)
PDE5A

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 180 27 7 7
Binding ≤ 1μM 155 23 6 4

Reactome Network (1)

Reactome ID Description Species
REACT_205403 cGMP effects Bos taurus
Uniprot Swissprot Chembl Description Number Shared
E1BN64_BOVIN E1BN64 CHEMBL5129 Phosphodiesterase 3B, Bovin 9
PDE1A_BOVIN P14100 CHEMBL3774 Phosphodiesterase 1A, Bovin 70
PDE1B_BOVIN Q01061 CHEMBL2650 Phosphodiesterase 1B, Bovin 56
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
PDE5A_HUMAN O76074 CHEMBL1827 Phosphodiesterase 5A, Human 1,222 69 13 7
PDE5A_RAT O54735 CHEMBL4567 Phosphodiesterase 5A, Rat 45 2 7 2

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
PDE5A-1-E Phosphodiesterase 5A (cluster #1 Of 2), Eukaryotic 1,340 89 16 9
PDE5A-2-E Phosphodiesterase 5A (cluster #2 Of 2), Eukaryotic 94 8 6 2
Uniprot Swissprot Chembl Description Number Shared
PDE1A_BOVIN P14100 CHEMBL3774 Phosphodiesterase 1A, Bovin 70
PDE1B_BOVIN Q01061 CHEMBL2650 Phosphodiesterase 1B, Bovin 56
PDE5A_HUMAN O76074 CHEMBL1827 Phosphodiesterase 5A, Human 22
PDE4D_HUMAN Q08499 CHEMBL288 Phosphodiesterase 4D, Human 15
PDE4A_HUMAN P27815 CHEMBL254 Phosphodiesterase 4A, Human 14
PDE4B_HUMAN Q07343 CHEMBL275 Phosphodiesterase 4B, Human 14
PDE4C_HUMAN Q08493 CHEMBL291 Phosphodiesterase 4C, Human 14
PDE6A_BOVIN P11541 CHEMBL3741 Phosphodiesterase 6A, Bovin 10
E1BN64_BOVIN E1BN64 CHEMBL5129 Phosphodiesterase 3B, Bovin 9
PDE11_HUMAN Q9HCR9 CHEMBL2717 Phosphodiesterase 11A, Human 7
PDE3A_HUMAN Q14432 CHEMBL241 Phosphodiesterase 3A, Human 6
PDE3B_HUMAN Q13370 CHEMBL290 Phosphodiesterase 3B, Human 6
PDE1A_HUMAN P54750 CHEMBL3421 Phosphodiesterase 1A, Human 4
PDE2A_BOVIN P14099 CHEMBL3477 Phosphodiesterase 2A, Bovin 4
Q864F1_PIG Q864F1 CHEMBL3634 Phosphodiesterase 5, Pig 4
CNCG_HUMAN Q13956 CHEMBL2341 Phosphodiesterase 6H, Human 3
CNRG_HUMAN P18545 CHEMBL2415 Phosphodiesterase 6G, Human 3
PDE1B_HUMAN Q01064 CHEMBL4425 Phosphodiesterase 1B, Human 3
PDE1C_HUMAN Q14123 CHEMBL4619 Phosphodiesterase 1C, Human 3
PDE6A_HUMAN P16499 CHEMBL3878 Phosphodiesterase 6A, Human 3
PDE6B_HUMAN P35913 CHEMBL3659 Phosphodiesterase 6B, Human 3
PDE6C_HUMAN P51160 CHEMBL3977 Phosphodiesterase 6C, Human 3
PDE6D_HUMAN O43924 CHEMBL3860 Phosphodiesterase 6D, Human 3
CNCG_BOVIN P22571 CHEMBL4606 Phosphodiesterase 6H, Bovin 2
CNRG_BOVIN P04972 CHEMBL5111 Phosphodiesterase 6G, Bovin 2
O77823_PIG O77823 CHEMBL3333 Phosphodiesterase 4A, Pig 2
PDE1B_RAT Q01066 CHEMBL3665 Phosphodiesterase 1B, Rat 2
PDE1C_RAT Q63421 CHEMBL2651 Phosphodiesterase 1C, Rat 2
PDE5A_RAT O54735 CHEMBL4567 Phosphodiesterase 5A, Rat 2
PDE6B_BOVIN P23439 CHEMBL2713 Phosphodiesterase 6B, Bovin 2
PDE6C_BOVIN P16586 CHEMBL3479 Phosphodiesterase 6C, Bovin 2
PDE6D_BOVIN Q95142 CHEMBL5110 Phosphodiesterase 6D, Bovin 2
Q9EPR9_RAT Q9EPR9 CHEMBL2740 Phosphodiesterase 1A, Rat 2
GBRA1_BOVIN P08219 CHEMBL3627 GABA Receptor Alpha-1 Subunit, Bovin 1
GBRA1_HUMAN P14867 CHEMBL1962 GABA Receptor Alpha-1 Subunit, Human 1
GBRA1_MOUSE P62812 CHEMBL3139 GABA Receptor Alpha-1 Subunit, Mouse 1
GBRA2_BOVIN P10063 CHEMBL2321 GABA Receptor Alpha-2 Subunit, Bovin 1
GBRA2_HUMAN P47869 CHEMBL4956 GABA Receptor Alpha-2 Subunit, Human 1
GBRA2_RAT P23576 CHEMBL341 GABA Receptor Alpha-2 Subunit, Rat 1
GBRA3_BOVIN P10064 CHEMBL3628 GABA Receptor Alpha-3 Subunit, Bovin 1
GBRA3_HUMAN P34903 CHEMBL3026 GABA Receptor Alpha-3 Subunit, Human 1
GBRA3_RAT P20236 CHEMBL328 GABA Receptor Alpha-3 Subunit, Rat 1
GBRA4_BOVIN P20237 CHEMBL3140 GABA Receptor Alpha-4 Subunit, Bovin 1
GBRA4_RAT P28471 CHEMBL292 GABA Receptor Alpha-4 Subunit, Rat 1
GBRA5_HUMAN P31644 CHEMBL5112 GABA Receptor Alpha-5 Subunit, Human 1
GBRA5_RAT P19969 CHEMBL300 GABA Receptor Alpha-5 Subunit, Rat 1
GBRA6_HUMAN Q16445 CHEMBL2579 GABA Receptor Alpha-6 Subunit, Human 1
GBRA6_RAT P30191 CHEMBL293 GABA Receptor Alpha-6 Subunit, Rat 1
GBRB1_BOVIN P08220 CHEMBL2848 GABA Receptor Beta-1 Subunit, Bovin 1
GBRB1_RAT P15431 CHEMBL334 GABA Receptor Beta-1 Subunit, Rat 1
GBRB2_RAT P63138 CHEMBL295 GABA Receptor Beta-2 Subunit, Rat 1
GBRB3_HUMAN P28472 CHEMBL1847 GABA Receptor Beta-3 Subunit, Human 1
GBRB3_RAT P63079 CHEMBL316 GABA Receptor Beta-3 Subunit, Rat 1
GBRD_RAT P18506 CHEMBL337 GABA Receptor Delta Subunit, Rat 1
GBRE_RAT Q9ES14 CHEMBL306 GABA Receptor Epsilon Subunit, Rat 1
GBRG1_RAT P23574 CHEMBL296 GABA Receptor Gamma-1 Subunit, Rat 1
GBRG2_BOVIN P22300 CHEMBL5138 GABA Receptor Gamma-2 Subunit, Bovin 1
GBRG2_HUMAN P18507 CHEMBL1788 GABA Receptor Gamma-2 Subunit, Human 1
GBRG2_RAT P18508 CHEMBL297 GABA Receptor Gamma-2 Subunit, Rat 1
GBRP_RAT O09028 CHEMBL294 GABA Receptor Pi Subunit, Rat 1
GBRR1_RAT P50572 CHEMBL3588 GABA Receptor Rho-1 Subunit, Rat 1
GBRR2_RAT P47742 CHEMBL2953 GABA Receptor Rho-2 Subunit, Rat 1
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 1
PDE10_HUMAN Q9Y233 CHEMBL4409 Phosphodiesterase 10A, Human 1
PDE3A_RAT Q62865 CHEMBL2711 Phosphodiesterase 3A, Rat 1
PDE3B_RAT Q63085 CHEMBL3580 Phosphodiesterase 3B, Rat 1
PDE4A_RAT P54748 CHEMBL4964 Phosphodiesterase 4A, Rat 1
PDE4B_RAT P14646 CHEMBL3382 Phosphodiesterase 4B, Rat 1
PDE4C_RAT P14644 CHEMBL4562 Phosphodiesterase 4C, Rat 1
PDE4D_RAT P14270 CHEMBL2712 Phosphodiesterase 4D, Rat 1
PDE9A_HUMAN O76083 CHEMBL3535 Phosphodiesterase 9A, Human 1
Q91ZM7_RAT Q91ZM7 CHEMBL305 GABA Receptor Theta Subunit, Rat 1
Q9XSW7_PIG Q9XSW7 CHEMBL3061 Phosphodiesterase 3A, Pig 1
Z104301 Z104301 CHEMBL1907607 GABA-A Receptor; Anion Channel 1
Z50590 Z50590 CHEMBL613488 Sus Scrofa 1