UCSF

GABA Transporter 1, Rat (105 Compounds)

Swissprot:
SC6A1_RAT
Stitch:
SC6A1_RAT
UniProt:
P23978
ChEMBL:
CHEMBL4054
Reactome:
REACT_244063
REACT_236779
PDB:
Slc6a1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 105 11 7 3
Binding ≤ 1μM 79 5 1 1
Functional ≤ 10μM 33 5 3 1

Reactome Network (2)

Reactome ID Description Species
REACT_244063 Na+/Cl- dependent neurotransmitter transporters Rattus norvegicus
REACT_236779 Reuptake of GABA Rattus norvegicus
Uniprot Swissprot Chembl Description Number Shared
S6A11_RAT P31647 CHEMBL3598 GABA Transporter 3, Rat 37
S6A12_RAT P48056 CHEMBL5248 Betaine Transporter, Rat 36

Reuptake of GABA

Uniprot Swissprot Chembl Description Number Shared
S6A11_RAT P31647 CHEMBL3598 GABA Transporter 3, Rat 37
S6A12_RAT P48056 CHEMBL5248 Betaine Transporter, Rat 36
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
SC6A1_HUMAN P30531 CHEMBL1903 GABA Transporter 1, Human 84 7 4 2
SC6A1_MOUSE P31648 CHEMBL5445 GABA Transporter 1, Mouse 23 5 2 1
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
SC6A3_RAT P23977 CHEMBL338 Dopamine Transporter, Rat 2,890 133 48 52
SC6A4_RAT P31652 CHEMBL313 Serotonin Transporter, Rat 3,586 155 40 53
SC6A5_RAT P58295 CHEMBL3195 Glycine Transporter 2, Rat 12 2 0 0
SC6A8_RAT P28570 CHEMBL3814 Creatine Transporter, Rat 2 0 0 0
SC6A9_RAT P28572 CHEMBL4556 Glycine Transporter 1, Rat 27 2 0 0

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
SC6A1-1-E GABA Transporter 1 (cluster #1 Of 2), Eukaryotic 196 7 2 1
SC6A1-2-E GABA Transporter 1 (cluster #2 Of 2), Eukaryotic 7 7 7 2
Uniprot Swissprot Chembl Description Number Shared
S6A11_RAT P31647 CHEMBL3598 GABA Transporter 3, Rat 36
S6A12_RAT P48056 CHEMBL5248 Betaine Transporter, Rat 36
S6A13_RAT P31646 CHEMBL4889 GABA Transporter 2, Rat 36
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 11
SC6A1_HUMAN P30531 CHEMBL1903 GABA Transporter 1, Human 7
SC6A1_MOUSE P31648 CHEMBL5445 GABA Transporter 1, Mouse 5
Z104301 Z104301 CHEMBL1907607 GABA-A Receptor; Anion Channel 3
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 2
EAA1_RAT P24942 CHEMBL4190 Excitatory Amino Acid Transporter 1, Rat 2
EAA2_RAT P31596 CHEMBL2900 Excitatory Amino Acid Transporter 2, Rat 2
EAA3_RAT P51907 CHEMBL3113 Excitatory Amino Acid Transporter 3, Rat 2
EAA4_RAT O35921 CHEMBL3700 Excitatory Amino Acid Transporter 4, Rat 2
GABR1_HUMAN Q9UBS5 CHEMBL2064 GABA-B Receptor 1, Human 1
GABR1_RAT Q9Z0U4 CHEMBL2753 GABA-B Receptor 1, Rat 1
GABR2_HUMAN O75899 CHEMBL5034 GABA-B Receptor 2, Human 1
GABR2_RAT O88871 CHEMBL4686 GABA-B Receptor 2, Rat 1
GBRA1_HUMAN P14867 CHEMBL1962 GABA Receptor Alpha-1 Subunit, Human 1
GBRA1_RAT P62813 CHEMBL343 GABA Receptor Alpha-1 Subunit, Rat 1
GBRA2_HUMAN P47869 CHEMBL4956 GABA Receptor Alpha-2 Subunit, Human 1
GBRA2_RAT P23576 CHEMBL341 GABA Receptor Alpha-2 Subunit, Rat 1
GBRA3_HUMAN P34903 CHEMBL3026 GABA Receptor Alpha-3 Subunit, Human 1
GBRA4_HUMAN P48169 CHEMBL2472 GABA Receptor Alpha-4 Subunit, Human 1
GBRA5_HUMAN P31644 CHEMBL5112 GABA Receptor Alpha-5 Subunit, Human 1
GBRA6_HUMAN Q16445 CHEMBL2579 GABA Receptor Alpha-6 Subunit, Human 1
GBRB1_HUMAN P18505 CHEMBL4558 GABA Receptor Beta-1 Subunit, Human 1
GBRB2_HUMAN P47870 CHEMBL1920 GABA Receptor Beta-2 Subunit, Human 1
GBRB3_HUMAN P28472 CHEMBL1847 GABA Receptor Beta-3 Subunit, Human 1
GBRD_HUMAN O14764 CHEMBL3591 GABA Receptor Delta Subunit, Human 1
GBRE_HUMAN P78334 CHEMBL4635 GABA Receptor Epsilon Subunit, Human 1
GBRG1_HUMAN Q8N1C3 CHEMBL4044 GABA Receptor Gamma-1 Subunit, Human 1
GBRG1_RAT P23574 CHEMBL296 GABA Receptor Gamma-1 Subunit, Rat 1
GBRG2_HUMAN P18507 CHEMBL1788 GABA Receptor Gamma-2 Subunit, Human 1
GBRG3_HUMAN Q99928 CHEMBL2739 GABA Receptor Gamma-3 Subunit, Human 1
GBRP_HUMAN O00591 CHEMBL3506 GABA Receptor Pi Subunit, Human 1
GBRR1_HUMAN P24046 CHEMBL3561 GABA Receptor Rho-1 Subunit, Human 1
GBRR2_HUMAN P28476 CHEMBL2375 GABA Receptor Rho-2 Subunit, Human 1
GBRR3_HUMAN A8MPY1 CHEMBL2394 GABA Receptor Rho-3 Subunit, Human 1
GBRT_HUMAN Q9UN88 CHEMBL2843 GABA Receptor Theta Subunit, Human 1
S6A11_HUMAN P48066 CHEMBL5208 GABA Transporter 3, Human 1