ZINC 12

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Quick Search ZINC ID or SMILES

Names
Compounds (105)
Reactome (2)
Related By:
Pathway (3)
Organism (2)
Gene (5)
Org. Clust. (1)
ChEMBL (39)
Rings (6)

GABA Transporter 1, Rat (105 Compounds)

Swissprot:: SC6A1_RAT
Stitch:: SC6A1_RAT
UniProt:: P23978
ChEMBL:: CHEMBL4054
Reactome:: REACT_244063; REACT_236779
PDB:: Slc6a1

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	105	11	7	3
Binding ≤ 1μM	79	5	1	1
Functional ≤ 10μM	33	5	3	1

Reactome ID	Description	Species
REACT_244063	Na+/Cl- dependent neurotransmitter transporters	Rattus norvegicus
REACT_236779	Reuptake of GABA	Rattus norvegicus

Uniprot	Swissprot	Chembl	Description	Number Shared
S6A11_RAT	P31647	CHEMBL3598	GABA Transporter 3, Rat	37
S6A12_RAT	P48056	CHEMBL5248	Betaine Transporter, Rat	36

Reuptake of GABA

Uniprot	Swissprot	Chembl	Description	Number Shared
S6A11_RAT	P31647	CHEMBL3598	GABA Transporter 3, Rat	37
S6A12_RAT	P48056	CHEMBL5248	Betaine Transporter, Rat	36

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
SC6A1_HUMAN	P30531	CHEMBL1903	GABA Transporter 1, Human	84	7	4	2
SC6A1_MOUSE	P31648	CHEMBL5445	GABA Transporter 1, Mouse	23	5	2	1

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
SC6A3_RAT	P23977	CHEMBL338	Dopamine Transporter, Rat	2,890	133	48	52
SC6A4_RAT	P31652	CHEMBL313	Serotonin Transporter, Rat	3,586	155	40	53
SC6A5_RAT	P58295	CHEMBL3195	Glycine Transporter 2, Rat	12	2	0	0
SC6A8_RAT	P28570	CHEMBL3814	Creatine Transporter, Rat	2	0	0	0
SC6A9_RAT	P28572	CHEMBL4556	Glycine Transporter 1, Rat	27	2	0	0

Clustered By Gene (0)

Clustered By Organism (1)

Code	Description	Substances	Purchasable	Natural	In Man
SC6A1-1-E	GABA Transporter 1 (cluster #1 Of 2), Eukaryotic	196	7	2	1
SC6A1-2-E	GABA Transporter 1 (cluster #2 Of 2), Eukaryotic	7	7	7	2

Uniprot	Swissprot	Chembl	Description	Number Shared
S6A11_RAT	P31647	CHEMBL3598	GABA Transporter 3, Rat	36
S6A12_RAT	P48056	CHEMBL5248	Betaine Transporter, Rat	36
S6A13_RAT	P31646	CHEMBL4889	GABA Transporter 2, Rat	36
Z50597	Z50597	CHEMBL376	Rattus Norvegicus	11
SC6A1_HUMAN	P30531	CHEMBL1903	GABA Transporter 1, Human	7
SC6A1_MOUSE	P31648	CHEMBL5445	GABA Transporter 1, Mouse	5
Z104301	Z104301	CHEMBL1907607	GABA-A Receptor; Anion Channel	3
AA3R_HUMAN	P33765	CHEMBL256	Adenosine A3 Receptor, Human	2
EAA1_RAT	P24942	CHEMBL4190	Excitatory Amino Acid Transporter 1, Rat	2
EAA2_RAT	P31596	CHEMBL2900	Excitatory Amino Acid Transporter 2, Rat	2
EAA3_RAT	P51907	CHEMBL3113	Excitatory Amino Acid Transporter 3, Rat	2
EAA4_RAT	O35921	CHEMBL3700	Excitatory Amino Acid Transporter 4, Rat	2
GABR1_HUMAN	Q9UBS5	CHEMBL2064	GABA-B Receptor 1, Human	1
GABR1_RAT	Q9Z0U4	CHEMBL2753	GABA-B Receptor 1, Rat	1
GABR2_HUMAN	O75899	CHEMBL5034	GABA-B Receptor 2, Human	1
GABR2_RAT	O88871	CHEMBL4686	GABA-B Receptor 2, Rat	1
GBRA1_HUMAN	P14867	CHEMBL1962	GABA Receptor Alpha-1 Subunit, Human	1
GBRA1_RAT	P62813	CHEMBL343	GABA Receptor Alpha-1 Subunit, Rat	1
GBRA2_HUMAN	P47869	CHEMBL4956	GABA Receptor Alpha-2 Subunit, Human	1
GBRA2_RAT	P23576	CHEMBL341	GABA Receptor Alpha-2 Subunit, Rat	1
GBRA3_HUMAN	P34903	CHEMBL3026	GABA Receptor Alpha-3 Subunit, Human	1
GBRA4_HUMAN	P48169	CHEMBL2472	GABA Receptor Alpha-4 Subunit, Human	1
GBRA5_HUMAN	P31644	CHEMBL5112	GABA Receptor Alpha-5 Subunit, Human	1
GBRA6_HUMAN	Q16445	CHEMBL2579	GABA Receptor Alpha-6 Subunit, Human	1
GBRB1_HUMAN	P18505	CHEMBL4558	GABA Receptor Beta-1 Subunit, Human	1
GBRB2_HUMAN	P47870	CHEMBL1920	GABA Receptor Beta-2 Subunit, Human	1
GBRB3_HUMAN	P28472	CHEMBL1847	GABA Receptor Beta-3 Subunit, Human	1
GBRD_HUMAN	O14764	CHEMBL3591	GABA Receptor Delta Subunit, Human	1
GBRE_HUMAN	P78334	CHEMBL4635	GABA Receptor Epsilon Subunit, Human	1
GBRG1_HUMAN	Q8N1C3	CHEMBL4044	GABA Receptor Gamma-1 Subunit, Human	1
GBRG1_RAT	P23574	CHEMBL296	GABA Receptor Gamma-1 Subunit, Rat	1
GBRG2_HUMAN	P18507	CHEMBL1788	GABA Receptor Gamma-2 Subunit, Human	1
GBRG3_HUMAN	Q99928	CHEMBL2739	GABA Receptor Gamma-3 Subunit, Human	1
GBRP_HUMAN	O00591	CHEMBL3506	GABA Receptor Pi Subunit, Human	1
GBRR1_HUMAN	P24046	CHEMBL3561	GABA Receptor Rho-1 Subunit, Human	1
GBRR2_HUMAN	P28476	CHEMBL2375	GABA Receptor Rho-2 Subunit, Human	1
GBRR3_HUMAN	A8MPY1	CHEMBL2394	GABA Receptor Rho-3 Subunit, Human	1
GBRT_HUMAN	Q9UN88	CHEMBL2843	GABA Receptor Theta Subunit, Human	1
S6A11_HUMAN	P48066	CHEMBL5208	GABA Transporter 3, Human	1