UCSF

Adenosine A2b Receptor, Rat (1,327 Compounds)

Swissprot:
AA2BR_RAT
Stitch:
AA2BR_RAT
UniProt:
P29276
ChEMBL:
CHEMBL2592
PDB:
Adora2b

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 1,327 64 16 11
Binding ≤ 1μM 909 42 9 7
Functional ≤ 10μM 108 10 5 2

Reactome Network (0)

UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
AA2BR_HUMAN P29275 CHEMBL255 Adenosine A2b Receptor, Human 1,141 51 14 12
AA2BR_MOUSE Q60614 CHEMBL2237 Adenosine A2b Receptor, Mouse 2 1 0 0

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
AA2AR_RAT P30543 CHEMBL302 Adenosine A2a Receptor, Rat 1341
AA1R_RAT P25099 CHEMBL318 Adenosine A1 Receptor, Rat 1189
AA1R_HUMAN P30542 CHEMBL226 Adenosine A1 Receptor, Human 160
AA2BR_HUMAN P29275 CHEMBL255 Adenosine A2b Receptor, Human 147
AA2AR_HUMAN P29274 CHEMBL251 Adenosine A2a Receptor, Human 140
AA3R_RAT P28647 CHEMBL3360 Adenosine A3 Receptor, Rat 122
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 57
AA1R_BOVIN P28190 CHEMBL4975 Adenosine A1 Receptor, Bovin 44
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 34
AA1R_CHICK P49892 CHEMBL2114 Adenosine A1 Receptor, Chick 18
AA2AR_CAVPO P46616 CHEMBL2605 Adenosine A2a Receptor, Guinea Pig 16
ADCY2_RAT P26769 CHEMBL2958 Adenylate Cyclase Type II, Rat 9
ADCY3_RAT P21932 CHEMBL4864 Adenylate Cyclase Type III, Rat 9
ADCY4_RAT P26770 CHEMBL2879 Adenylate Cyclase Type IV, Rat 9
ADCY5_RAT Q04400 CHEMBL2880 Adenylate Cyclase Type V, Rat 9
ADCY6_RAT Q03343 CHEMBL2975 Adenylate Cyclase Type VI, Rat 9
ADCY8_RAT P40146 CHEMBL3082 Adenylate Cyclase Type VIII, Rat 9
OXGR1_RAT Q6Y1R5 CHEMBL2325 G Protein-coupled Receptor 80, Rat 7
Z100273 Z100273 CHEMBL612413 P3 Purinoceptor 5
SAHH_HUMAN P23526 CHEMBL2664 Adenosylhomocysteinase, Human 4
5HT1A_MOUSE Q64264 CHEMBL3737 Serotonin 1a (5-HT1a) Receptor, Mouse 3
ADA2A_RAT P22909 CHEMBL327 Alpha-2a Adrenergic Receptor, Rat 3
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 3
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 3
S29A1_HUMAN Q99808 CHEMBL1997 Equilibrative Nucleoside Transporter 1, Human 3
Z50512 Z50512 CHEMBL369 Cavia Porcellus 3
5HT2A_BOVIN Q75Z89 CHEMBL3446 Serotonin 2a (5-HT2a) Receptor, Bovin 2
AA1R_MOUSE Q60612 CHEMBL3688 Adenosine A1 Receptor, Mouse 2
ADA_BOVIN P56658 CHEMBL2966 Adenosine Deaminase, Bovin 2
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 2
Q4VQ11_PIG Q4VQ11 CHEMBL1075029 A1 Adenosine Receptor, Pig 2
Z50588 Z50588 CHEMBL373 Canis Familiaris 2
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 1
AA2AR_MOUSE Q60613 CHEMBL2115 Adenosine A2a Receptor, Mouse 1
AA2BR_MOUSE Q60614 CHEMBL2237 Adenosine A2b Receptor, Mouse 1
AA3R_MOUSE Q61618 CHEMBL1075269 Adenosine Receptor A3, Mouse 1
ADA_HUMAN P00813 CHEMBL1910 Adenosine Deaminase, Human 1
ADCY1_HUMAN Q08828 CHEMBL2899 Brain Adenylate Cyclase 1, Human 1
ADCY2_HUMAN Q08462 CHEMBL3760 Adenylate Cyclase Type II, Human 1
ADCY3_HUMAN O60266 CHEMBL3164 Adenylate Cyclase Type III, Human 1
ADCY5_HUMAN O95622 CHEMBL3189 Adenylate Cyclase Type V, Human 1
ADCY6_HUMAN O43306 CHEMBL3221 Adenylate Cyclase Type VI, Human 1
ADCY7_HUMAN P51828 CHEMBL4922 Adenylate Cyclase Type VII, Human 1
ADCY8_HUMAN P40145 CHEMBL2960 Adenylate Cyclase Type VIII, Human 1
ADCY9_HUMAN O60503 CHEMBL2655 Adenylate Cyclase Type IX, Human 1
ADK_TOXGO Q9TVW2 CHEMBL2982 Adenosine Kinase, Toxgo 1
ANDR_HUMAN P10275 CHEMBL1871 Androgen Receptor, Human 1
AOFB_HUMAN P27338 CHEMBL2039 Monoamine Oxidase B, Human 1
AOFB_MOUSE Q8BW75 CHEMBL3050 Monoamine Oxidase B, Mouse 1
CHLE_HUMAN P06276 CHEMBL1914 Butyrylcholinesterase, Human 1
CP19A_HUMAN P11511 CHEMBL1978 Cytochrome P450 19A1, Human 1
CP1B1_HUMAN Q16678 CHEMBL4878 Cytochrome P450 1B1, Human 1
DRD2_BOVIN P20288 CHEMBL3998 Dopamine D2 Receptor, Bovin 1
GBRA1_HUMAN P14867 CHEMBL1962 GABA Receptor Alpha-1 Subunit, Human 1
GBRA2_HUMAN P47869 CHEMBL4956 GABA Receptor Alpha-2 Subunit, Human 1
GBRA3_HUMAN P34903 CHEMBL3026 GABA Receptor Alpha-3 Subunit, Human 1
GBRA4_HUMAN P48169 CHEMBL2472 GABA Receptor Alpha-4 Subunit, Human 1
GBRA5_HUMAN P31644 CHEMBL5112 GABA Receptor Alpha-5 Subunit, Human 1
GBRA6_HUMAN Q16445 CHEMBL2579 GABA Receptor Alpha-6 Subunit, Human 1
GBRB1_HUMAN P18505 CHEMBL4558 GABA Receptor Beta-1 Subunit, Human 1
GBRB2_HUMAN P47870 CHEMBL1920 GABA Receptor Beta-2 Subunit, Human 1
GBRB3_HUMAN P28472 CHEMBL1847 GABA Receptor Beta-3 Subunit, Human 1
GBRD_HUMAN O14764 CHEMBL3591 GABA Receptor Delta Subunit, Human 1
GBRE_HUMAN P78334 CHEMBL4635 GABA Receptor Epsilon Subunit, Human 1
GBRG1_HUMAN Q8N1C3 CHEMBL4044 GABA Receptor Gamma-1 Subunit, Human 1
GBRG2_HUMAN P18507 CHEMBL1788 GABA Receptor Gamma-2 Subunit, Human 1
GBRG3_HUMAN Q99928 CHEMBL2739 GABA Receptor Gamma-3 Subunit, Human 1
GBRP_HUMAN O00591 CHEMBL3506 GABA Receptor Pi Subunit, Human 1
GBRT_HUMAN Q9UN88 CHEMBL2843 GABA Receptor Theta Subunit, Human 1
GRP78_HUMAN P11021 CHEMBL1781865 78 KDa Glucose-regulated Protein, Human 1
MDR3_MOUSE P21447 CHEMBL2573 P-glycoprotein 3, Mouse 1
P4K2A_HUMAN Q9BTU6 CHEMBL2251 PI4-kinase Type II, Human 1
P4K2B_HUMAN Q8TCG2 CHEMBL3220 PI4-kinase Type II Beta, Human 1
PDE1A_BOVIN P14100 CHEMBL3774 Phosphodiesterase 1A, Bovin 1
PDE1A_HUMAN P54750 CHEMBL3421 Phosphodiesterase 1A, Human 1
PDE1B_BOVIN Q01061 CHEMBL2650 Phosphodiesterase 1B, Bovin 1
PDE1B_HUMAN Q01064 CHEMBL4425 Phosphodiesterase 1B, Human 1
PDE1B_RAT Q01066 CHEMBL3665 Phosphodiesterase 1B, Rat 1
PDE1C_HUMAN Q14123 CHEMBL4619 Phosphodiesterase 1C, Human 1
PDE1C_RAT Q63421 CHEMBL2651 Phosphodiesterase 1C, Rat 1
PDE3A_HUMAN Q14432 CHEMBL241 Phosphodiesterase 3A, Human 1
PDE3B_HUMAN Q13370 CHEMBL290 Phosphodiesterase 3B, Human 1
PDE4A_HUMAN P27815 CHEMBL254 Phosphodiesterase 4A, Human 1
PDE4B_HUMAN Q07343 CHEMBL275 Phosphodiesterase 4B, Human 1
PDE4C_HUMAN Q08493 CHEMBL291 Phosphodiesterase 4C, Human 1
PDE4D_HUMAN Q08499 CHEMBL288 Phosphodiesterase 4D, Human 1
PDE5A_HUMAN O76074 CHEMBL1827 Phosphodiesterase 5A, Human 1
PDE7A_HUMAN Q13946 CHEMBL3012 Phosphodiesterase 7A, Human 1
PDE7B_HUMAN Q9NP56 CHEMBL4716 Phosphodiesterase 7B, Human 1
PI4KA_HUMAN P42356 CHEMBL3667 PI4-kinase Alpha Subunit, Human 1
PI4KB_HUMAN Q9UBF8 CHEMBL3268 PI4-kinase Beta Subunit, Human 1
Q9EPR9_RAT Q9EPR9 CHEMBL2740 Phosphodiesterase 1A, Rat 1
S29A1_RAT O54698 CHEMBL4604 Equilibrative Nucleoside Transporter 1, Rat 1
SCN1A_HUMAN P35498 CHEMBL1845 Sodium Channel Protein Type I Alpha Subunit, Human 1
SCN2A_HUMAN Q99250 CHEMBL4187 Sodium Channel Protein Type II Alpha Subunit, Human 1
SCN3A_HUMAN Q9NY46 CHEMBL5163 Sodium Channel Protein Type III Alpha Subunit, Human 1
SCN8A_HUMAN Q9UQD0 CHEMBL5202 Sodium Channel Protein Type VIII Alpha Subunit, Human 1
XDH_HUMAN P47989 CHEMBL1929 Xanthine Dehydrogenase, Human 1
Z100081 Z100081 CHEMBL613107 PBMC (Peripheral Blood Mononuclear Cells) 1
Z104301 Z104301 CHEMBL1907607 GABA-A Receptor; Anion Channel 1
Z50587 Z50587 CHEMBL372 Homo Sapiens 1

Most Common Rings